Aliases for CARD17 Gene
External Ids for CARD17 Gene
GeneCards Summary for CARD17 Gene
CARD17 (Caspase Recruitment Domain Family, Member 17) is a Protein Coding gene. Diseases associated with CARD17 include shigellosis. Among its related pathways are Interferon Signaling and Signaling by Interleukins. GO annotations related to this gene include cysteine-type endopeptidase activity and cysteine-type endopeptidase inhibitor activity. An important paralog of this gene is CARD18.
UniProtKB/Swiss-Prot for CARD17 Gene
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.