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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CARD14 Gene

protein-coding   GIFtS: 53
GCID: GC17P078152

caspase recruitment domain family, member 14

 Explore 5 diseases affiliated with
CARD14 via our new
 Human Malady Compendium 
Biological research products
for CARD14
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Caspase Recruitment Domain Family, Member 141 2     PSORS22
CARMA21 2 3     PSS12
BIMP21 2     Bcl10-Interacting Maguk Protein 22
Carma 22 3     Card-Maguk Protein 22
CARD-Containing MAGUK Protein 22 3     Caspase Recruitment Domain-Containing Protein 142
PRP2     

External Ids:    HGNC: 164461   Entrez Gene: 790922   Ensembl: ENSG000001415277   OMIM: 6072115   UniProtKB: Q9BXL63   

Export aliases for CARD14 gene to outside databases

Previous GC identifers: GC17M077760 GC17P081455 GC17P078714 GC17P078852 GC17P078843 GC17P075766 GC17P073593


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CARD14:
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate
kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse
array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein
has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell
apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. (provided by RefSeq,
Apr 2012)

UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6
Function: Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10

Gene Wiki entry for CARD14


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CARD14 gene promoter:
         Lmo2   NF-kappaB1   NF-kappaB   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): CARD14 promoter sequence
   Search SABiosciences Chromatin IP Primers for CARD14

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CARD14


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25

CARD14 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CARD14 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P078152:  view genomic region     (about GC identifiers)

Start:
78,143,791 bp from pter      End:
78,183,130 bp from pter
Size:
39,340 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6 (See protein sequence)
Recommended Name: Caspase recruitment domain-containing protein 14  
Size: 1004 amino acids; 113270 Da
Subunit: CARD14 and BCL10 bind to each other by CARD-CARD interaction
Subcellular location: Cytoplasm
Caution: Supposed to contain a SH3 domain which is not detected by PROSITE, Pfam or SMART
Sequence caution: Sequence=AAH01326.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q9BVB5

Explore the universe of human proteins at neXtProt for CARD14: NX_Q9BXL6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BXL6

  • CARD14 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001244899.1  NP_077015.2  NP_438170.1  

    ENSEMBL proteins: 
     ENSP00000461447   ENSP00000458715   ENSP00000459244   ENSP00000460883   ENSP00000461806  
     ENSP00000460405   ENSP00000344549   ENSP00000376229  

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    Novus Biologicals CARD14 Proteins
    Novus Biologicals CARD14 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CARD14

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane NAS11278692
    GO:0016235aggresome IDA--


    CARD14 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CARD14 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR008144 Guanylate_kin
     IPR008145 Guanylate_kin/L-typ_Ca_channel
     IPR011029 DEATH-like_dom
     IPR001478 PDZ
     IPR001315 CARD

    Graphical View of Domain Structure for InterPro Entry Q9BXL6

    ProtoNet protein and cluster: Q9BXL6

    2 Blocks protein families:
    IPB001315 CARD interaction domain
    IPB001478 PDZ/DHR/GLGF domain


    UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6
    Similarity: Contains 1 CARD domain
    Similarity: Contains 1 guanylate kinase-like domain
    Similarity: Contains 1 PDZ (DHR) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6
    Function: Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10

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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CARD14

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050700CARD domain binding IPI11278692


    CARD14 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Card14tm1Lex for CARD14
         1 MGI phenotypic allele for Card14 (no phenotypes)

    CARD14 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NF-KappaB Family Pathway
    NF-KappaB Family Pathway1.00
    2PKC-Theta Pathway
    PKC-Theta Pathway1.00

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CARD14
        PKC-Theta Pathway
    NF-KappaB Family Pathway


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CARD14

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for CARD14 (Q9BXL62, 3 ENSP000003445494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIP13Q156452, 3, ENSP000001663454MINT-66683 I2D: score=4 STRING: ENSP00000166345
    BCL10O959993, ENSP000002710154I2D: score=2 STRING: ENSP00000271015
    ZNF471Q9BX823I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001934positive regulation of protein phosphorylation IDA11278692
    GO:0007250activation of NF-kappaB-inducing kinase activity NAS11278692
    GO:0042981regulation of apoptotic process IEA--


    CARD14 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CARD14
    Search CenterWatch for drugs/clinical trials and news about CARD14 / CAR14 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CARD14 gene (3 alternative transcripts): 
    NM_001257970.1  NM_024110.4  NM_052819.2  

    Unigene Clusters for CARD14:

    Caspase recruitment domain family, member 14
    Hs.675480 , Hs.696253  [show with all ESTs]
    Unigene Representative Sequences: AK002138, NR_047566
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000576785 ENST00000573489 ENST00000573882(uc002jxt.1) ENST00000575465
    ENST00000575500 ENST00000571427(uc002jxu.1) ENST00000570421(uc002jxv.3)
    ENST00000572838 ENST00000571450 ENST00000573754(uc002jxx.3) ENST00000571861
    ENST00000574148 ENST00000575666(uc010dhu.1) ENST00000344227(uc002jxw.1 uc010wud.1)
    ENST00000392434

    miRNA
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CARD14
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CARD14

    Additional cDNA sequence: 

    AF322642.1 AK054723.1 AK091123.1 AK095416.1 AK296762.1 AK309299.1 AY032927.1 BC001326.1 
    BC018142.1 EU652409.1 NR_047566.1 

    10 DOTS entries:

    DT.75139610  DT.91818001  DT.75152696  DT.91876590  DT.99999323  DT.101979121  DT.95131152  DT.95207040 
    DT.65288757  DT.111991 

    24/33 AceView cDNA sequences (see all 33):

    BU956261 BC001326 BC018142 BI040409 NM_052819 AK095416 BE891229 AI291007 
    BX477520 AW341258 AK002138 NM_024110 AK054723 BE543447 AK091123 AW150635 
    AI950942 AW573094 AF322642 AX746790 AY032927 AI559852 BU617627 AI188883 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CARD14 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b ^ 15 ^ 16a ·
    SP1:                    -     -                                   -     -           -                                   -                       -               
    SP2:                    -     -                                   -     -           -           -                       -                       -               
    SP3:                    -     -                                   -     -           -                                   -                       -               
    SP4:                                                                    -           -                                   -                       -               
    SP5:                                                                                                                                                            

    ExUns: 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24a · 24b
    SP1:  -                 -                 -                                 
    SP2:  -                 -                                                   
    SP3:  -                                                                     
    SP4:                                                                        
    SP5:                                                                        


    ECgene alternative splicing isoforms for CARD14

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CARD14 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGCCCCTTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CARD14 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CARD14

    SOURCE GeneReport for Unigene clusters: Hs.675480 Hs.696253

    UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6
    Tissue specificity: Expressed in placenta. Also detected in HeLaS3 cell line, but not in the other cancer cell lines
    tested. Expressed in epidermal keratinocytes

        SABiosciences Expression via Pathway-Focused PCR Array including CARD14: 
              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CARD14

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CARD14 gene from 2/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia CARD146
    --
    56(a)
    1 ↔ 1
    2(100563961-100582077)
    zebrafish
    (Danio rerio)
    Actinopterygii CR854963.36
    --
    35(a)
    1 ↔ 1
    6(19563810-19611703)


    ENSEMBL Gene Tree for CARD14 (if available)
    TreeFam Gene Tree for CARD14 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CARD14 gene
    CARD112  CARD102  CARD92  
    1 SIMAP similar gene for CARD14 using alignment to 7 protein entries:     CAR14_HUMAN (see all proteins):
    CARD11

    CARD14 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/951 NCBI SNPs in CARD14 are shown (see all 951    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs285290651,2
    C,F--73607225(+) GGGGAC/ACCGAT 1 -- int12Minor allele frequency- A:0.50NA WA 4
    rs1165256441,2
    C,F,--78141824(+) ACAGGG/ATCCTT 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs1160875001,2
    --78141884(+) GTTCCG/AGGATA 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs121501181,2
    C,F,--78141919(+) TACATA/GAGTAG 1 -- us2k110Minor allele frequency- G:0.38NA WA CSA EA 255
    rs1823123421,2
    --78141947(+) TTGCTA/TCACCT 1 -- us2k10--------
    rs126003901,2
    H--78141966(+) atcacC/Ttaggt 1 -- us2k10--------
    rs116498971,2
    C,H--78142086(+) ttcagC/Ttccca 1 -- us2k10--------
    rs797120471,2
    C,--78142129(+) CTGTTC/ACCATG 1 -- us2k12Minor allele frequency- A:0.06WA 120
    rs1869649321,2
    --78142191(+) CCCTTC/GATTCC 1 -- us2k10--------
    rs1436186211,2
    --78142222(+) CTATTC/TCTATG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CARD14 (78143791 - 78183130 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for CARD14
         3 CNVs: 2235 8853 3154
         1 Indel: 40209
    Human Gene Mutation Database (HGMD): CARD14

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CARD14 for disorders           About GeneDecksing

    OMIM gene information: 607211    OMIM disorders: --

    UniProtKB/Swiss-Prot: CAR14_HUMAN, Q9BXL6
  • Defects in CARD14 are the cause of susceptibility to psoriasis type 2 (PSORS2) [MIM:602723]. A common, chronic
  • inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found
    on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of
    inflammatory cells into the dermis and epidermis
  • Defects in CARD14 are the cause of pityriasis rubra pilaris (PRP) [MIM:173200]. A rare, papulosquamous skin
  • disease characterized by the appearance of keratotic follicular papules, well-demarcated salmon-colored erythematous
    plaques covered with fine powdery scales interspersed with distinct islands of uninvolved skin, and palmoplantar
    keratoderma. Most cases are sporadic. The rare familial cases show autosomal dominant inheritance with incomplete
    penetrance and variable expression. Familial PRP usually presents at birth or appears during the first years of life
    and runs a chronic course. It is characterized by prominent follicular hyperkeratosis, diffuse palmoplantar
    keratoderma, and erythema

    5 diseases for CARD14:    About MalaCards
    pityriasis rubra pilaris    moyamoya disease    hepatitis b    hepatitis
    psoriasis

    Human Genome Epidemiology (HuGE) Navigator: CARD14 (4 documents)

    Export disorders for CARD14 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CARD14 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with CARD14)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with Bcl10 and activate NF-kappaB. (PubMed id 11278692)1, 2, 3 Bertin J.... Alnemri E.S. (2001)
    2. Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation. (PubMed id 11356195)1, 2, 3 Gaide O.... Tschopp J. (2001)
    3. Rare and Common Variants in CARD14, Encoding an Epidermal Regulator of NF-kappaB, in Psoriasis. (PubMed id 22521419)1, 2 Jordan C.T.... Bowcock A.M. (2012)
    4. PSORS2 is due to mutations in CARD14. (PubMed id 22521418)1, 2 Jordan C.T.... Bowcock A.M. (2012)
    5. Familial pityriasis rubra pilaris is caused by mutations in CARD14. (PubMed id 22703878)1, 2 Fuchs-Telem D.... Sprecher E. (2012)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Alternative splicing of CARMA2/CARD14 transcripts gen erates protein variants with differential effect on NF-I_B activation and endopl asmic reticulum stress-induced cell death. (PubMed id 21302310)1 Scudiero I....Stilo R. (2011)
    8. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    9. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1 Oguri M....Yamada Y. (2010)
    10. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1 Yoshida T....Yamada Y. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79092 HGNC: 16446 AceView: CARD14 Ensembl:ENSG00000141527 euGenes: HUgn79092
    ECgene: CARD14 H-InvDB: CARD14

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CARD14 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CARD14 gene:
    Search GeneIP for patents involving CARD14

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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