Aliases for CARD10 Gene
External Ids for CARD10 Gene
Previous GeneCards Identifiers for CARD10 Gene
The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008]
GeneCards Summary for CARD10 Gene
CARD10 (Caspase Recruitment Domain Family Member 10) is a Protein Coding gene. Among its related pathways are GPCR Pathway and TCR Signaling (Qiagen). GO annotations related to this gene include receptor signaling complex scaffold activity. An important paralog of this gene is CARD11.
UniProtKB/Swiss-Prot for CARD10 Gene
Activates NF-kappa-B via BCL10 and IKK.