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CARD10 Gene

protein-coding GIFtS: 57

GC22M036210

caspase recruitment domain family, member 10
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
BIMP1 ^¹, ², ⁵
CARMA3 ^¹, ², ³, ⁵
MGC142219 ^²

Descriptions
Bcl10 binding protein and activator of NFKB ^²
CARD-containing MAGUK 3 protein ^²
CARD-containing MAGUK protein 3 ^³
Carma 3 ^³
caspase recruitment domain family, member 10 ^²
caspase recruitment domain protein 10 ^²

External Ids
HGNC: 16422¹
Entrez Gene: 29775²
UniProtKB: Q9BWT7³
Ensembl: ENSG00000100065⁷

Search outside databases for aliases for CARD10 gene

Previous GC identifers: GC22M034500 GC22M036129

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CARD10:

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel

alpha helices. It participates in apoptosis signaling through highly specific protein-protein

homophilic interactions. Like several other CARD proteins, CARD10 belongs to the

membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM

164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM]

UniProtKB/Swiss-Prot: CAR10_HUMAN, Q9BWT7

Function: Activates NF-kappa-B via BCL10 and IKK

Gene Wiki entry for CARD10

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CARD10 gene

Entrez Gene cytogenetic band: 22q13.1 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13.1

CARD10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 22 GeneLoc Exon Structure

GeneLoc location for GC22M036210: (about GC identifiers)

Start:	36,216,346 bp from pter
End:	36,245,495 bp from pter
Size:	29,150 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000022.9 NT_011520.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CAR10_HUMAN, Q9BWT7 (See protein sequence)

Recommended Name: Caspase recruitment domain-containing protein 10

Size: 1032 amino acids; 115931 Da

Subunit: CARD10 and BCL10 bind to each other by CARD-CARD interaction. They both participate in a

complex with MALT1, where MALT1 binds to BCL10 (By similarity)

Subcellular location: Cytoplasm (By similarity)

Caution: Supposed to contain a SH3, a PDZ and a guanylate kinase-like domain. But none of these 3

domains are detected by PROSITE, Pfam or SMART

Secondary accessions: Q14CQ8 Q5TFG6 Q9UGR5 Q9UGR6 Q9Y3H0

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_055365.2

ENSEMBL proteins:

ENSP00000385799 ENSP00000384570 ENSP00000251973

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CARD10)
	Human Recombinant Proteins from Abnova (CARD10)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--
GO:0005737	cytoplasm	NAS	11259443
GO:0032449	CBM complex	NAS	15125833

About this table

Antibodies for CARD10:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for CARD10
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (CARD10), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibody for CARD10

Assays for CARD10:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9BWT7

ProtoNet protein and cluster: Q9BWT7

1 Blocks protein family: IPB001315 CARD interaction domain

UniProtKB/Swiss-Prot: CAR10_HUMAN, Q9BWT7

Similarity: Contains 1 CARD domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CARD10)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014550

Applied Biosystems Silencer® siRNAs for CARD10

Sigma-Aldrich siRNA for CARD10

Sigma-Aldrich shRNA for CARD10

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_014550
Myc/DDK tagged cDNA clone in CMV expression vector: NM_014550
untagged cDNA clone in CMV expression vector: NM_014550

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_014550

UniProtKB/Swiss-Prot: CAR10_HUMAN, Q9BWT7

Function: Activates NF-kappa-B via BCL10 and IKK

4 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Card10):

craniofacial

lethality-prenatal/perinatal

nervous system

skeleton

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	11259443
GO:0030159	receptor signaling complex scaffold activity	NAS	11259443

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for CARD10 (Your Favorite Gene powered by Ingenuity)

NF-&kappa
B Cell Receptor Signaling

GeneDecks CARD10 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for CARD10

5/7 Interacting proteins for CARD10 (ENSP00000251973³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
BCL10	ENSP00000271015³	STRING (score=.999)
MALT1	ENSP00000319279³	STRING (score=.996)
IKBKG	ENSP00000358622³	STRING (score=.972)
GUK1	ENSP00000355680³	STRING (score=.935)
IKBKB	ENSP00000339151³	STRING (score=.89)

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006461	protein complex assembly	NAS	11259443
GO:0007250	activation of NF-kappaB-inducing kinase activity	IDA	11259443
GO:0042981	regulation of apoptosis	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CARD10

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CARD10)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_014550

Sigma-Aldrich siRNA for CARD10

Sigma-Aldrich shRNA for CARD10

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_014550

REFSEQ mRNAs for CARD10 gene:

NM_014550.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_014550

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_014550
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_014550
                                 untagged cDNA clone in CMV expression vector: NM_014550

Additional cDNA sequence:

AF086324.1 AK074906.1 AK296176.1 AY028896.1 AY032928.1 BC032058.1 BC113659.1 BC117403.1

10 DOTS entries:

DT.309950 DT.95272280 DT.101961630 DT.100028856 DT.100028855 DT.120648630 DT.120648667 DT.91814521

DT.99971659 DT.95272279

24/113 AceView cDNA sequences (see all 113 ):

AW024347 AI829451 BQ690010 BI764337 AI739413 AW138129 BM980824 BE906442

BI792107 AI948904 BQ691608 AW612524 AW137435 BE048709 AI948914 AW969602

BQ688908 AA397734 BE465866 AA513369 CA489572 CD625764 AF086324 BU145814

highest scoring ESTs for CARD10:

AY028896 AY032928 BG717357 CA489572 AA113168 AA397734 AA399648 AA513369 AA609085 AA642933

Unigene Cluster for CARD10:

Caspase recruitment domain family, member 10

Hs.57973 [show with all ESTs]

Unigene Representative Sequence: AY028896

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for CARD10 (see all 12 )

ExUns:	1	^	2a	·	2b	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15a	·	15b	·	15c	^	16a	·	16b	·	16c	^	17a	·	17b	^	18a	·	18b	^
SP1:																																							-		-
SP2:
SP3:																	-
SP4:																															-		-						-		-
SP5:

ExUns:	19	^	20a	·	20b	·	20c	^	21	^	22a	·	22b	^	23	^	24a	·	24b
SP1:			-
SP2:			-
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for CARD10

3 Ensembl transcripts including schematic representations:

ENST00000406271 ENST00000403299 ENST00000251973

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CARD10 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CARD10

¹ / ² / ³

6 probe-sets matching CARD10 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41816_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.90	AL049851	0.20	1.00	0.72	1
41817_g_at²^{, 3}	U95-A	2	1.00	0.97	0.92	1.10	AL049851	0.20	1.00	0.72	1
210026_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AY028896	0.80	1.00	0.91	1
210025_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AW205153	0.60	1.00	0.82	1
210026_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
210025_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGAATGTACG

SOURCE GeneReport for Unigene cluster: Hs.57973
Expression variation in blood from EXPOLDB for CARD10
UniProtKB/Swiss-Prot: CAR10_HUMAN, Q9BWT7
Tissue specificity: Detected in adult heart, kidney and liver; lower levels in intestine, placenta,
muscle and lung. Also found in fetal lung, liver and kidney

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CARD10 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CARD10¹	--	caspase recruitment domain family, member 10	89.79(n) 93(a)	481268 XM_538389.2 XP_538389.2
chimpanzee (Pan troglodytes)	CARD10¹	--	caspase recruitment domain family, member 10	98.8(n) 98.83(a)	458812 XM_001160660.1 XP_001160660.1
cow (Bos taurus)	CARD10¹	--	caspase recruitment domain family, member 10	89.54(n) 92.57(a)	535188 XM_615197.3 XP_615197.3
rat (Rattus norvegicus)	Card10¹	--	caspase recruitment domain family, member 10	85.75(n) 91.08(a)	315120 XM_243622.4 XP_243622.4
mouse (Mus musculus)	Card10^{1, 5}	15⁵	caspase recruitment domain family, member 10^{1, 5}	86.67(n)¹ 91.67(a)¹	105844¹ NM_130859.2¹ NP_570929.1¹ AF363456⁵ AI449026⁵ (see all 10)

About this table Species with no ortholog for CARD10

ENSEMBL Gene Tree for CARD10

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CARD10 gene

CARD14² CARD11² CARD9²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/271 NCBI SNPs in CARD10 are shown (see all 271 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 94)

AB	SNP ID	Valid	Chr 22 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs9610775^1,2	A,C,F,H	36236208(+)	`TCAGCC/TGCTGG`	1	R/Q	mis¹ ese³		4		EU EA WA	416
	rs7290274^1,2	A,C,F,H	36245861(+)	`GGGGCT/CTTCTG`	1	--	ng3¹		4		EA WA	474
--	rs5750441^1,2	A,C,F	36216474(+)	`AGGCAT/CAGGCA`	1	--	ut3¹ ese³		1		--	836
	rs3817805^1,2	A,C,F,H	36230708(+)	`GAATGG/AGAGGA`	1	S/S	syn¹		4		EU EA WA	412
	rs3817803^1,2	A,C,F,H	36230222(+)	`AGCCGA/GTTGAT`	1	N/N	syn¹ ese³		14		EA EU WA NA	2734
	rs3817802^1,2	C,F	36230189(+)	`GAGCCG/AGCACT`	1	A/A	syn¹		1		EA	1500
	rs5756709^1,2	H	36241988(+)	`TGCCAG/AGCGCA`	1	L/L	syn¹ ese³		4		EU EA WA	416
--	rs7287804^1,2	A	36245046(+)	`AGCCGA/GTGCCG`	1	H/H	syn¹ ese³		0	--	--	--	--
	rs932326^1,2	A,C,F,H,O	36234903(+)	`GTTCAC/GCCAGG`	1	--	int¹		12		EU EA WA NA	1050
	rs5750442^1,2	A,C,F,H	36222036(+)	`GGCCAA/TAGACA`	1	--	int¹		5		EU EA WA	1254

About this table

HapMap Linkage Disequilibrium images for CARD10 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 607209

Human Genome Epidemiology Navigator: CARD10 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/17 PubMed articles for CARD10 gene (see all 17 ):

CARD10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with Bcl10 and activates NF-kappa B. (PubMed id 11259443)^{2, 3, 4} Wang L.... Bertin J. (2001)
Carma1, a CARD-containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation. (PubMed id 11356195)^{2, 3, 4} Gaide O....Tschopp J. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 22. (PubMed id 10591208)^{3, 4} Dunham I....O'Brien K.P. (1999)
CARMA3 mediates lysophosphatidic acid-stimulated cytokine secretion by bronchial epithelial cells. (PubMed id 18757306)^{1, 3} Medoff B.D....Xavier R.J. (2009)
A20 is a negative regulator of BCL10- and CARMA3-mediated activation of NF-kappaB. (PubMed id 18349075)^{1, 3} Stilo R....Vito P. (2008)
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complex. (PubMed id 19112107)³ Martin D....Gutkind J.S. (2009)
Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)³ Hosgood H.D....Lan Q. (2008)
Protein kinase C alpha-CARMA3 signaling axis links Ras to NF-kappa B for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. (PubMed id 17724468)³ Mahanivong C....Huang S. (2008)
CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cells. (PubMed id 17101977)³ McAllister-Lucas L.M....Lucas P.C. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 29775	HGNC: 16422	AceView: CARD10	Ensembl:ENSG00000100065	euGenes: HUgn29775
ECgene: CARD10	H-InvDB: CARD10

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for CARD10
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CARD10:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CARD10-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CARD10		Antibodies for CARD10
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CARD10		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CARD10)
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	Custom Service for Rabbit Pab from Full-length Protein

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Search OriGene for CARD10

Search Tocris compounds for CARD10

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CARD10

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

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CARD10 Gene at Home site.
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CARD10 Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for CARD10

Summaries
for CARD10

Genomic Location
for CARD10

Proteins
for CARD10

Protein Domains/
Families
for CARD10

Gene Function
for CARD10

Pathways & Interactions
for CARD10

Drugs & Compounds
for CARD10

Transcripts
for CARD10

Expression
for CARD10

Orthologs
for CARD10

Paralogs
for CARD10

SNPs/Variants
for CARD10

Disorders & Mutations
for CARD10

Medical News
for CARD10

Publications
for CARD10

Search for CARD10

Genome Databases showing CARD10

Other Databases showing CARD10

Specialized Databases showing CARD10

Licensable Technologies
for CARD10

Services
for CARD10

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CARD10 Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor CARD10

Summariesfor CARD10

Genomic Locationfor CARD10

Proteinsfor CARD10

Protein Domains/Familiesfor CARD10

Gene Functionfor CARD10

Pathways & Interactionsfor CARD10

Drugs & Compoundsfor CARD10

Transcriptsfor CARD10

Expression for CARD10

Orthologsfor CARD10

Paralogsfor CARD10

SNPs/Variantsfor CARD10

Disorders & Mutationsfor CARD10

Medical Newsfor CARD10

Publicationsfor CARD10

Search for CARD10

Genome Databases showing CARD10

Other Databases showing CARD10

Specialized Databases showing CARD10

Licensable Technologiesfor CARD10

Servicesfor CARD10

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CARD10

Summaries
for CARD10

Genomic Location
for CARD10

Proteins
for CARD10

Protein Domains/
Families
for CARD10

Gene Function
for CARD10

Pathways & Interactions
for CARD10

Drugs & Compounds
for CARD10

Transcripts
for CARD10

Expression
for CARD10

Orthologs
for CARD10

Paralogs
for CARD10

SNPs/Variants
for CARD10

Disorders & Mutations
for CARD10

Medical News
for CARD10

Publications
for CARD10

Licensable Technologies
for CARD10

Services
for CARD10