CAPZB Gene
protein-coding GIFtS: 63
GCID: GC01M019665
|
|
capping protein (actin filament) muscle Z-line, beta
| |
Aliases for CAPZB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Capping Protein (Actin Filament) Muscle Z-Line, Beta1 2 | | CapZ Beta2 3 | | CAPPB2 5 | | CAPB2 | | CAPZ2 | | F-Actin-Capping Protein Subunit Beta2 |
| External Ids: | HGNC: 14911 | Entrez Gene: 8322 | Ensembl: ENSG000000775497 | OMIM: 6015725 | UniProtKB: P477563 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n410721 | |
Export aliases for CAPZB gene to outside databasesPrevious GC identifers: GC01M019225 GC01M018690 GC01M018811 GC01M019135 GC01M019134 GC01M019410 GC01M019537 GC01M017911
Summaries for CAPZB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CAPZB: This gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin cappingprotein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly anddisassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well asin stabilizing actin filament lengths in muscle and nonmuscle cells. Multiple alternatively spliced transcriptvariants encoding different isoforms have been found.(provided by RefSeq, Apr 2011) UniProtKB/Swiss-Prot: CAPZB_HUMAN, P47756Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolinand severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology andcytoskeletal organization Gene Wiki entry for CAPZB
|
Genomic Views for CAPZB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CAPZB gene promoter: AML1a MEF-2 Ik-3 MZF-1 MEF-2A FAC1 Ik-2 POU2F1 POU2F1a aMEF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for CAPZB
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPZB |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.1 Ensembl cytogenetic band: 1p36.13 HGNC cytogenetic band: 1p36.1CAPZB Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M019665: view genomic region
(about GC identifiers)
Start:
|
19,665,267 bp from pter |
End:
|
19,812,066 bp from pter |
Size:
|
146,800 bases |
Orientation:
|
minus strand |
|
Proteins for CAPZB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CAPZB_HUMAN, P47756 (See
protein sequence)Recommended Name: F-actin-capping protein subunit beta Size: 277 amino acids; 31350 Da
Subunit: Heterodimer of an alpha and a beta subunit. Interacts with ARHGAP17 and RCSD1/CAPZIP. Component of the WASHcomplex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunitbeta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033,KIAA0196 and CCDC53
Subcellular location: Cytoplasm, cytoskeleton (By similarity)
Secondary accessions: Q32Q68 Q5U0L4 Q8TB49 Q9NUC4Alternative splicing: 3 isoforms: P47756-1 P47756-2 P47756-3 Explore the universe of human proteins at neXtProt for CAPZB: NX_P47756
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P47756 CAPZB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001193469.1 NP_004921.1 ENSEMBL proteins: ENSP00000264203 ENSP00000364286 ENSP00000364284 ENSP00000401010 ENSP00000392781 ENSP00000400757 ENSP00000383862 ENSP00000264202 Reactome Protein details: P47756 Human Recombinant Protein Products:
Gene Ontology (GO): 5/9 cellular component terms (GO ID links to tree view) (see all 9): About this table
CAPZB for ontologies About GeneDecksing
CAPZB Antibody Products: Assay Products for CAPZB: |
Protein
Domains / Families for CAPZB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CAPZB for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P47756ProtoNet protein and cluster: P47756 1 Blocks protein family: IPB001698 F-actin capping protein
UniProtKB/Swiss-Prot: CAPZB_HUMAN, P47756Similarity: Belongs to the F-actin-capping protein beta subunit family |
Function for CAPZB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CAPZB_HUMAN, P47756Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolinand severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology andcytoskeletal organization Genatlas biochemistry entry for CAPZB:actin-capping protein Z,beta subunit 1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CAPZB (NM_004930) | |  | Sino Biological Human cDNA Clone for CAPZB | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPZB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPZB  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPZB |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CAPZB for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CAPZB: Animal Models: 3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Capzb):
CAPZB for phenotypes About GeneDecksing
|
Pathways & Interactions for CAPZB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cytoskeleton remodeling Neurofilaments | | | 2 | Cell cycle_Spindle assembly and chromosome separation | | | 3 | Factors involved in megakaryocyte development and platelet production | | | 4 | Platelet activation, signaling and aggregation | |
Pathway sources See GeneCards unified pathways Show all pathways
3 EMD Millipore Pathways for CAPZB
2 GeneGo (Thomson Reuters) Pathways for CAPZB 2
Reactome Pathways for CAPZB
CAPZB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAPZB
5/105 Interacting proteins for CAPZB (P477562, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 105)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
CAPZB for ontologies About GeneDecksing
|
Drugs & Compounds for CAPZB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CAPZB Search CenterWatch for drugs/clinical trials and news about CAPZB 
|
Transcripts for CAPZB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CAPZB gene (3 alternative transcripts): NM_001206540.1 NM_004930.3 NM_001206541.1 Unigene Cluster for CAPZB: Capping protein (actin filament) muscle Z-line, beta Hs.432760 [show with all ESTs]Unigene Representative Sequence: NR_03812511 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264203(uc009vpk.3) ENST00000375144 ENST00000375142 ENST00000433834 ENST00000413711 ENST00000459967 ENST00000457768 ENST00000489607 ENST00000482808 ENST00000401084(uc010ocz.2 uc001bce.3 uc021ohr.1) ENST00000264202
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CAPZB (NM_004930) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPZB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPZB  |
Additional cDNA sequence: AK125085.1 AK301442.1 AK313113.1 BC008095.1 BC012305.1 BC024601.1 BC107752.1 BC109241.1 BC109242.1 BT019470.1 BT019471.1 NR_038125.1 U03271.1 24/38 DOTS entries (see all 38): DT.97863846 DT.92461301 DT.85104988 DT.95279935 DT.100881833 DT.100881810 DT.100881814 DT.100881835 DT.85101948 DT.95115140 DT.95137668 DT.121420932 DT.40200863 DT.100881832 DT.40116293 DT.95220605 DT.97760109 DT.100881812 DT.100881825 DT.121421089 DT.40116290 DT.95187152 DT.95220509 DT.100881816 24/819 AceView cDNA sequences (see all 819): BF876422 CB153755 BX423008 BQ649251 AA430524 AW193131 BU623792 AI567992 AA909820 BU151117 BF970705 BQ959244 BI856646 CR622250 CR595642 BI916209 BC008095 CR615786 BQ057928 CD364764 CR615877 CR609341 BU179541 CD557935 GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for CAPZB (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | |
| SP1: | |   | |   | |   | - |   | - |   | - |   | |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |
| SP2: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |
| SP3: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 19a | · | 19b | · | 19c | |
| SP1: | |   | |   | |   | |
| SP2: | |   | |   | |   | |
| SP3: | |   | |   | |   | |
| SP4: | |   | |   | |   | |
| SP5: | |   | |   | |   |
ECgene alternative splicing isoforms for CAPZB
|
Expression for CAPZB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CAPZB expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CTAACCAGAC
About this image See CAPZB Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CAPZB
SOURCE GeneReport for Unigene cluster: Hs.432760 SABiosciences Custom PCR Arrays for CAPZB
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPZB Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAPZB | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPZB | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPZB | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPZB |
Orthologs for CAPZB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CAPZB gene from 10/36 species (see all 36) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Capzb1 , 5 |
capping protein (actin filament) muscle Z-line, beta1, 5 |
92.77(n)1 100(a)1 |
  |
4 (70.59 cM)5 123451 NM_009798.31 NP_033928.11 1391928995 |
chicken (Gallus gallus) |
Aves |
CAPZB1 |
capping protein (actin filament) muscle Z-line, beta |
88.07(n) 99.26(a) |
  |
396418 NM_001173529.1 NP_001167000.1 |
lizard (Anolis carolinensis) |
Reptilia |
CAPZB6 |
-- |
97(a) |
1 ↔ 1 |
GL343959.1(15482-15577) |
African clawed frog (Xenopus laevis) |
Amphibia |
capzb-prov2 |
capping protein beta 1 |
83.86(n) |
  |
BC041233.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufk65f062 |
wufk65f06 |
78.97(n) |
  |
335083 BC055514.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
cpb1 , 3 |
F-actin capping3 capping protein beta1 |
81(a)3 71(n)1 81.78(a)1 |
  |
2 22B13 333461 NM_057657.41 NP_477005.11 |
worm (Caenorhabditis elegans) |
Secernentea |
cap-21 , 3 |
F-actin capping protein beta subunit3 Protein CAP-21 |
66(a)3 62.55(n)1 67.04(a)1 |
  |
II(10869140-10870324)3 1746731 NM_063935.51 NP_496336.11 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
CAP2(YIL034C)4 CAP21 |
Beta subunit of the capping protein (CP) heterodimer more4 Cap2p1 |
52.02(n)1 51.14(a)1 |
  |
9(290089-289226)4 8547771, 4 NP_012230.31 NP_012230.14 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT1G717901 |
capping protein (actin filament) muscle Z-line, beta |
56.84(n) 54.7(a) |
  |
843509 NM_105837.3 NP_177324.2 |
rice (Oryza sativa) |
Liliopsida |
Os.157642 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
75.41(n) |
  |
AK061302.1 |
ENSEMBL Gene Tree for CAPZB (if available) TreeFam Gene Tree for CAPZB (if available)  |
Paralogs for CAPZB gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for CAPZB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CAPZB (19665267 - 19812066 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 4 variations for CAPZB 4 Indels: 10859 41589 60804 44486  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPZB |
|
Disorders
/ Diseases for CAPZB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CAPZB for disorders About GeneDecksing
OMIM gene information: 601572
OMIM disorders: --
10 diseases for CAPZB: About MalaCardsposterior uveitis chronic lymphocytic leukemia lymphocytic leukemia goiter uveitis choroiditis leukemia retinitis thyroiditis malaria Human Genome Epidemiology (HuGE) Navigator: CAPZB (2 documents) Export disorders for CAPZB gene to outside databases
|
Publications for CAPZB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CAPZB gene, integrated from 9 sources (see all 56): (articles sorted by number of sources associating them with CAPZB) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sequence analysis and chromosomal localization of human Cap Z. Conserved residues within the actin-binding domain may link Cap Z to gelsolin/severin and profilin protein families. (PubMed id 7665558)1, 2, 9 Barron-Casella E.A.... Casella J.F. (1995)
- The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. (PubMed id 19922875)1, 2 Derivery E.... Gautreau A. (2009)
- A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. (PubMed id 16678097)1, 2 Wells C.D.... Pawson T. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Sp1 phosphorylation by cyclin-dependent kinase 1/cycli n B1 represses its DNA-binding activity during mitosis in cancer cells. (PubMed id 22266860)1 Chuang J.Y....Hung J.J. (2012)
- Meta-analysis of two genome-wide association studies i dentifies four genetic loci associated with thyroid function. (PubMed id 22494929)1 Rawal R....Homuth G. (2012)
|
External Searches for CAPZB gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CAPZB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CAPZB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CAPZB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for CAPZB gene: Search GeneIP for patents involving CAPZB
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for CAPZB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for CAPZB | | OriGene shRNA RFP for CAPZB | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAPZB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPZB | | OriGene Protein Over-expression Lysate for CAPZB | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CAPZB | | OriGene 3'-UTR Clone for CAPZB | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPZB | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for CAPZB | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CAPZB | | OriGene Custom Protein Services for CAPZB | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAPZB | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPZB | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPZB | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAPZB | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPZB | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPZB |
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| | | Search Tocris compounds for CAPZB |
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 | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPZB |
|  |  |  | | | ThermoFisher Antibody for CAPZB |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPZB |
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