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CAPZA3 Gene

protein-coding   GIFtS: 50
GCID: GC12P018891

Capping Protein (Actin Filament) Muscle Z-Line, Alpha 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Capping Protein (Actin Filament) Muscle Z-Line, Alpha 31 2     Gsg32
Germ Cell-Specific Protein 32 3     F-Actin Capping Protein Alpha-3 Subunit2
CP-alpha-32 3     F-Actin-Capping Protein Subunit Alpha-32
CapZ Alpha-32 3     CAPAA33
CAPPA32 5     GSG33

External Ids:    HGNC: 242051   Entrez Gene: 936612   Ensembl: ENSG000001779387   OMIM: 6087225   UniProtKB: Q96KX23   

Export aliases for CAPZA3 gene to outside databases

Previous GC identifers: GC12P018782 GC12P018660


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CAPZA3 Gene:
This gene encodes an actin capping protein, one of the F-actin capping protein alpha subunit family. The encoded
protein is predominantly localized to the neck region of ejaculated sperm, other immunohistochemical signals were
found in the tail and postacrosomal regions. The encoded protein may also form heterodimers of alpha and beta
subunits. This protein may be important in determining sperm architecture and male fertility. (provided by
RefSeq, Jul 2008)

GeneCards Summary for CAPZA3 Gene:
CAPZA3 (capping protein (actin filament) muscle Z-line, alpha 3) is a protein-coding gene. GO annotations related to this gene include actin binding. An important paralog of this gene is CAPZA1.

UniProtKB/Swiss-Prot: CAZA3_HUMAN, Q96KX2
Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments
(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as
gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of
spermatid (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_009714.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the CAPZA3 gene promoter:
         AML1a   Nkx2-2   HSF1 (long)   Cdc5   NF-AT   HOXA5   FOXJ2 (long isoform)   HSF1short   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCAPZA3 promoter sequence
   Search Chromatin IP Primers for CAPZA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAPZA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12.3   Ensembl cytogenetic band:  12p12.3   HGNC cytogenetic band: 12p12.3

CAPZA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAPZA3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P018891:  view genomic region     (about GC identifiers)

Start:
18,891,045 bp from pter      End:
18,892,122 bp from pter
Size:
1,078 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CAZA3_HUMAN, Q96KX2 (See protein sequence)
Recommended Name: F-actin-capping protein subunit alpha-3  
Size: 299 amino acids; 35025 Da
Subunit: Heterodimer of an alpha and a beta subunit (By similarity). Component of the WASH complex, composed of
F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB),
WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and
CCDC53
Secondary accessions: Q969J0

Explore the universe of human proteins at neXtProt for CAPZA3: NX_Q96KX2

Explore proteomics data for CAPZA3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CAPZA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_201585.1  
    ENSEMBL proteins: 
     ENSP00000326238  

    CAPZA3 Human Recombinant Protein Products:

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    Novus Biologicals CAPZA3 Proteins
    Novus Biologicals CAPZA3 Lysates
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CAPZA3 

    CAPZA3 Antibody Products:

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    LSBio Antibodies in human, mouse, rat for CAPZA3

    CAPZA3 Assay Products:

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    Browse ELISAs at Cloud-Clone Corp.
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    Search eBioscience for ELISAs for CAPZA3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR017865 F-actin_cap_asu_CS
     IPR002189 CapZ_alpha

    Graphical View of Domain Structure for InterPro Entry Q96KX2

    ProtoNet protein and cluster: Q96KX2

    1 Blocks protein domain: IPB002189 F-actin capping protein

    UniProtKB/Swiss-Prot: CAZA3_HUMAN, Q96KX2
    Similarity: Belongs to the F-actin-capping protein alpha subunit family


    Find genes that share domains with CAPZA3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAZA3_HUMAN, Q96KX2
    Function: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments
    (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as
    gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of
    spermatid (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
         
    Find genes that share ontologies with CAPZA3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CAPZA3:
     Increased G1 DNA content 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Capza3):
     reproductive system 

    Find genes that share phenotypes with CAPZA3           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CAPZA3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CAPZA3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CAPZA3
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    Predesigned siRNA for gene silencing in human, mouse, rat CAPZA3

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPZA3

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001669acrosomal vesicle IEA--
    GO:0008290F-actin capping protein complex IEA--
    GO:0016020membrane IEA--
    GO:0030863cortical cytoskeleton IEA--
    GO:0071203WASH complex IEA--

    Find genes that share ontologies with CAPZA3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CAPZA3 About    
    See pathways by source

    SuperPathContained pathways About
    1Cytoplasmic microtubules
    Cytoplasmic microtubules0.32
    Cytoskeleton remodeling Neurofilaments0.32
    2Cell cycle Spindle assembly and chromosome separation
    Cell cycle Spindle assembly and chromosome separation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 GeneGo (Thomson Reuters) Pathways for CAPZA3
        Cell cycle Spindle assembly and chromosome separation
    Cytoskeleton remodeling Neurofilaments


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CAPZA3
    Interactions:

        Search GeneGlobe Interaction Network for CAPZA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CAPZA3 (Q96KX23 ENSP000003262384) via UniProtKB, MINT, STRING, and/or I2D (see all 72)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAPZA2P477553, ENSP000003549474I2D: score=1 STRING: ENSP00000354947
    ACTG1P632613, ENSP000003315144I2D: score=1 STRING: ENSP00000331514
    CAP1ENSP000003618784STRING: ENSP00000361878
    CAP2ENSP000002299224STRING: ENSP00000229922
    ADD1ENSP000002647584STRING: ENSP00000264758
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007286spermatid development IEA--
    GO:0030036actin cytoskeleton organization IEA--
    GO:0051693actin filament capping IEA--

    Find genes that share ontologies with CAPZA3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CAPZA3 (CAZA3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CAPZA3 gene: 
    NM_033328.2  

    Unigene Cluster for CAPZA3:

    Capping protein (actin filament) muscle Z-line, alpha 3
    Hs.131288  [show with all ESTs]
    Unigene Representative Sequence: BM553031
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000317658(uc001rdy.3)
    miRNA
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CAPZA3 (NM_033328)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAPZA3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPZA3
    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat CAPZA3
      QuantiFast Probe-based Assays in human, mouse, rat CAPZA3

    Additional mRNA sequence: 

    AB053259.1 AK058174.1 BC016745.2 

    1 DOTS entry:

    DT.406966 

    20 AceView cDNA sequences:

    CD359623 AK058174 NM_033328 BP370577 BC016745 BM554108 AB053259 AI798168 
    BG772483 BM553031 BI462232 AI018424 AI214488 AI654717 AA923335 AI018423 
    AI027287 AA973833 BU569656 BP371336 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CAPZA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGAGAAAAA
    CAPZA3 Expression
    About this image


    CAPZA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 14 entries
             Multinuclear Myocytes Lumbar Back Muscles
     
     Limb (Muscoskeletal System)    fully expand to see all 4 entries
             Multinuclear Myocytes Forelimb Dorsal Muscles
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Elongated Spermatid Seminiferous Tubules
             sperm   
     
     Gonad
             Elongated Spermatid Seminiferous Tubules
    CAPZA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CAPZA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.131288

    UniProtKB/Swiss-Prot: CAZA3_HUMAN, Q96KX2
    Tissue specificity: Expressed exclusively in testis and sperm. Highest expression is found in the neck region of
    ejaculated sperm with lower levels found in the tail and postacrosome region

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPZA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CAPZA3 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Capza31 , 5 capping protein (actin filament) muscle Z-line, alpha more1, 5 84.73(n)1
    91.3(a)1
      6 (69.77 cM)5
    123441  NM_007605.41  NP_031631.31 
     1400415575 
    chicken
    (Gallus gallus)
    Aves CAPZA31 capping protein (actin filament) muscle Z-line, alpha more 54.7(n)
    39.93(a)
      427929  NM_001278118.1  NP_001265047.1 
    lizard
    (Anolis carolinensis)
    Reptilia CAPZA36
    capping protein (actin filament) muscle Z-line, al...
    39(a)
    1 ↔ 1
    5(9512913-9513740)
    zebrafish
    (Danio rerio)
    Actinopterygii capza1a6
    capza1b6
    capping protein (actin filament) muscle Z-line, al...
    capping protein (actin filament) muscle Z-line, al...
    34(a)
    34(a)
    many → 1
    many → 1
    6(48263842-48287992) ENSDARG00000034240
    8(28660917-28669785) ENSDARG00000056090
    fruit fly
    (Drosophila melanogaster)
    Insecta cpa6
    capping protein alpha
    31(a)
    1 → many
    2R(16945276-16947388)
    worm
    (Caenorhabditis elegans)
    Secernentea cap-16
    Protein CAP-1 (cap-1) mRNA, complete cds
    28(a)
    1 → many
    IV(7228337-7230223) WBGene00000292
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CAP16
    Alpha subunit of the capping protein (CP) heterodi...
    23(a)
    1 → many
    XI(429302-430108) YKL007W


    ENSEMBL Gene Tree for CAPZA3 (if available)
    TreeFam Gene Tree for CAPZA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CAPZA3 gene
    CAPZA12  CAPZA22  
    2 SIMAP similar genes for CAPZA3 using alignment to 1 protein entry:     CAZA3_HUMAN:
    CAPZA1    CAPZA2

    Find genes that share paralogs with CAPZA3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    1 SNPs for CAPZA3    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs768404441,2
    C,F--18661613(+) AAAAAT/CCTAGC 1 -- ds50011Minor allele frequency- C:0.05EA 120

    HapMap Linkage Disequilibrium report for CAPZA3 (18891045 - 18892122 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CAPZA3: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CAPZA3
    DNA2.0 Custom Variant and Variant Library Synthesis for CAPZA3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608722    OMIM disorders: --


    Find genes that share disorders with CAPZA3           About GenesLikeMe

    Genetic Association Database (GAD): CAPZA3
    Human Genome Epidemiology (HuGE) Navigator: CAPZA3 (3 documents)

    Export disorders for CAPZA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CAPZA3 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with CAPZA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of the human orthologue of male germ cell-specific actin capping protein alpha3 (cpalpha3). (PubMed id 12029070)1, 2, 3, 9 Miyagawa Y.... Nishimune Y. (Mol. Hum. Reprod. 2002)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Genome-wide association study of the five-factor model of personality in young Korean women. (PubMed id 23903073)1 Kim H.N....Kim H.L. (J. Hum. Genet. 2013)
    6. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    7. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    8. The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex. (PubMed id 19922875)2 Derivery E.... Gautreau A. (Dev. Cell 2009)
    9. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)4 Levy D....Mitchell G.F. (BMC Med. Genet. 2007)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 93661 HGNC: 24205 AceView: CAPZA3 Ensembl:ENSG00000177938 euGenes: HUgn93661
    ECgene: CAPZA3 H-InvDB: CAPZA3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CAPZA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CAPZA3 gene:
    Search GeneIP for patents involving CAPZA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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