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Set Analyses:

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CAPS Gene

protein-coding GIFtS: 52
GCID: GC19P005911

Calcyphosine

See related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Calcyphosine³
calcyphosine¹ ²
Calcyphosine 1¹ ²
Thyroid Protein P24¹ ²
CAPS1²
calcyphosin²

External Ids:	HGNC: 1487¹	Entrez Gene: 828²	Ensembl: ENSG00000105519⁷	OMIM: 114212⁵	UniProtKB: Q13938³

Export aliases for CAPS gene to outside databases

Previous GC identifers: GC19P006006 GC19P005851 GC19P005865 GC19P005673

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CAPS Gene:

This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar

protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as

R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. (provided by RefSeq,

Jul 2008)

GeneCards Summary for CAPS Gene:

CAPS (calcyphosine) is a protein-coding gene. Diseases associated with CAPS include thyroiditis, and antiphospholipid syndrome. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CAPSL.

UniProtKB/Swiss-Prot: CAYP1_HUMAN, Q13938

Function: Calcium-binding protein. May play a role in cellular signaling events (Potential)

Gene Wiki entry for CAPS Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000019.10 NT_011295.12 NC_018930.2

Regulatory elements:

Regulatory transcription factor binding sites in the CAPS gene promoter:
FAC1 AP-1 ATF-2 MIF-1 c-Jun Pax-4a C/EBPalpha
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CAPS promoter sequence

Search Chromatin IP Primers for CAPS

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAPS

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3

CAPS Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAPS gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P005911: view genomic region (about GC identifiers)

Start:	5,911,718 bp from pter	End:	5,916,222 bp from pter
Size:	4,505 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CAYP1_HUMAN, Q13938 (See protein sequence)

Recommended Name: Calcyphosin

Size: 189 amino acids; 20967 Da

Subunit: Monomer. Does not form oligomers in the presence of calcium

1 PDB 3D structure from and Proteopedia for CAPS:

3E3R (3D)

Secondary accessions: Q3MJA7 Q8WUZ3

Explore the universe of human proteins at neXtProt for CAPS: NX_Q13938

Explore proteomics data for CAPS at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See CAPS Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_004049.1 NP_542157.1

ENSEMBL proteins:

ENSP00000465883 ENSP00000222125 ENSP00000403263 ENSP00000468582

CAPS Human Recombinant Protein Products:

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CAPS Antibody Products:

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CAPS Assay Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

EFHAND: EF-hand domain containing

3 InterPro protein domains:

IPR011992 EF-hand-dom_pair

IPR002048 EF_hand_dom

IPR018247 EF_Hand_1_Ca_BS

Graphical View of Domain Structure for InterPro Entry Q13938

ProtoNet protein and cluster: Q13938

UniProtKB/Swiss-Prot: CAYP1_HUMAN, Q13938

Similarity: Contains 4 EF-hand domains

CAPS for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: CAYP1_HUMAN, Q13938

Function: Calcium-binding protein. May play a role in cellular signaling events (Potential)

Genatlas biochemistry entry for CAPS:

calcyphosine,calcium binding protein

Gene Ontology (GO): 1 molecular function term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--

CAPS for ontologies About GeneDecksing

Animal Models:

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genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CAPS

miRNA Products:		Block miRNA regulation of human, mouse, rat CAPS using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate CAPS (see all 17):
		hsa-miR-411* hsa-miR-2052 hsa-miR-323-3p hsa-miR-19b-2* hsa-miR-379* hsa-miR-631 hsa-miR-219-5p hsa-miR-3661

		SwitchGear 3'UTR luciferase reporter plasmid: CAPS 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPS

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

CAYP1_HUMAN, Q13938: Cytoplasm

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	4
plasma membrane	4
cytosol	3

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005737	cytoplasm	IDA	--
GO:0005886	plasma membrane	IDA	--

CAPS for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for CAPS
Interactions:

GeneGlobe Interaction Network for CAPS

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

Selected Interacting proteins for CAPS (ENSP00000222125⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 7)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
KIAA1549	ENSP00000242365⁴	STRING: ENSP00000242365
PIP5K1A	ENSP00000357883⁴	STRING: ENSP00000357883
RAD1	ENSP00000340879⁴	STRING: ENSP00000340879
HORMAD1	ENSP00000355167⁴	STRING: ENSP00000355167
HORMAD2	ENSP00000336984⁴	STRING: ENSP00000336984

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Gene Ontology (GO): 1 biological process term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0035556	intracellular signal transduction	TAS	2540953

CAPS for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for CAPS (CAYP1)

1 HMDB Compound for CAPS About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CAPS gene (2 alternative transcripts):

NM_004058.3 NM_080590.2

Unigene Cluster for CAPS:

Calcyphosine

Hs.584744 [show with all ESTs]

Unigene Representative Sequence: AK090469

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000588776 ENST00000222125(uc002mdt.3) ENST00000452990(uc002mdu.3)

ENST00000590428 ENST00000585541 ENST00000588865

miRNA Products:		Block miRNA regulation of human, mouse, rat CAPS using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate CAPS (see all 17):
		hsa-miR-411* hsa-miR-2052 hsa-miR-323-3p hsa-miR-19b-2* hsa-miR-379* hsa-miR-631 hsa-miR-219-5p hsa-miR-3661

		SwitchGear 3'UTR luciferase reporter plasmid: CAPS 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for CAPS
		Predesigned siRNA for gene silencing in human, mouse, rat CAPS

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Primer Products:		OriGene qPCR primer pairs and template standards for CAPS OriGene qSTAR qPCR primer pairs in human, mouse for CAPS
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat CAPS
		QuantiTect SYBR Green Assays in human, mouse, rat CAPS
		QuantiFast Probe-based Assays in human, mouse, rat CAPS

Additional mRNA sequence:

AK090469.1 AK123559.1 AK226026.1 BC011961.1 BC080599.1 BC101513.1 BC104766.1 X97966.1

6 DOTS entries:

DT.312821 DT.97760083 DT.100659278 DT.99976177 DT.99975780 DT.95288317

Selected AceView cDNA sequences (see all 186):

CR601253 BM699638 AW151211 AI560810 AW510425 CA396674 BE396135 AI924700

BQ673321 AW513409 BM712749 BQ436748 BG767590 AI628545 CF128141 BG950416

BU689238 AI624988 BM716373 CK821926 CR623055 AI613142 BQ673294 BM725337

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for CAPS About this scheme

ExUns:	1a	·	1b	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b
SP1:									-
SP2:									-				-
SP3:

ECgene alternative splicing isoforms for CAPS

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CAPS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CTGACCAGAG

About this image

CAPS Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

CAPS Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.584744

Custom PCR Arrays for CAPS

Primer Products:		OriGene qPCR primer pairs and template standards for CAPS OriGene qSTAR qPCR primer pairs in human, mouse for CAPS
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat CAPS
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		QuantiFast Probe-based Assays in human, mouse, rat CAPS

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPS

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for CAPS gene from Selected species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
dog (Canis familiaris)	Mammalia	CAPS¹	calcyphosine	88.36(n) 91.01(a)		403965 NM_001003282.1 NP_001003282.1
zebrafish (Danio rerio)	Actinopterygii	capsla⁶	calcyphosine-like a	55(a)	many ↔ many	2(54479382-54485838) ENSDARG00000039341
fruit fly (Drosophila melanogaster)	Insecta	CG10126³	calcium ion binding	47(a)		87D2 --

ENSEMBL Gene Tree for CAPS (if available)
TreeFam Gene Tree for CAPS (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for CAPS gene

CAPSL² CAPS2²

5 SIMAP similar genes for CAPS using alignment to 3 protein entries: CAYP1_HUMAN (see all proteins):

FLJ00390 CAPSL CAPS2 SLC25A24 TNNC2

CAPS for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs188020531^1,2		--	5912237(+)	`GGCACA/GATCTC`	2	--	us2k¹		0	--	--	--	--
rs11882811^1,2	C,H	--	5912330(+)	`caccaC/Tgccca`	2	--	us2k¹ ese³		1		NA	2
rs274788^1,2	C,F,A	--	5912464(+)	`gccacC/Tgcacc`	2	--	us2k¹ ese³		4		NA WA	8
rs190890413^1,2		--	5912638(+)	`GAGGCA/GGGCGT`	2	--	us2k¹		0	--	--	--	--
rs274787^1,2	C,F,A	--	5912641(+)	`gcgggC/Ggtctt`	2	--	us2k¹ ese³		7		NA WA CSA	247
rs111490026^1,2	C	--	5912678(+)	`TGGTGC/TGATCA`	2	--	us2k¹		0	--	--	--	--
rs183055000^1,2		--	5912711(+)	`CCCGGA/GCTCAA`	2	--	us2k¹		0	--	--	--	--
rs274786^1,2	C,F	--	5912812(+)	`gggggG/Ttctca`	2	--	us2k¹		4		NA WA	242
rs187390423^1,2		--	5912854(+)	`GGCTCA/GAGTGA`	2	--	us2k¹		0	--	--	--	--
rs193108692^1,2		--	5912909(+)	`GCCACC/TGCGCT`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CAPS (5911718 - 5916222 bp)

Structural Variations
Database of Genomic Variants (DGV) 5 variations for CAPS: About this table

Variant ID	Type	Subtype	PubMed ID
nsv910905	CNV	Loss	21882294
nsv910906	CNV	Loss	21882294
nsv910904	CNV	Loss	21882294
nsv910907	CNV	Loss	21882294
dgv3693n71	CNV	Loss	21882294

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing CAPS

DNA2.0 Custom Variant and Variant Library Synthesis for CAPS

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 114212 OMIM disorders: --

3 diseases for CAPS: About MalaCards

thyroiditis antiphospholipid syndrome anorexia nervosa

CAPS for disorders About GeneDecksing

Genetic Association Database (GAD): CAPS
Human Genome Epidemiology (HuGE) Navigator: CAPS (43 documents)

Export disorders for CAPS gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CAPS gene, integrated from 10 sources (see all 17):
(articles sorted by number of sources associating them with CAPS)

Utopia: connect your pdf to the dynamic
world of online information

Cloning and sequence analysis of human calcyphosine complementary DNA. (PubMed id 9224948)^{1, 2, 3, 9} el Housni H.... Christophe D. (Biochim. Biophys. Acta 1997)
Localization of human calcyphosine gene (CAPS) to the p13.3 region of chromosome 19 by in situ hybridization. (PubMed id 2265558)^{1, 3, 9} Lefort A....Mattei M.G. (Cytogenet. Cell Genet. 1990)
Association study of 182 candidate genes in anorexia nervosa. (PubMed id 20468064)^{1, 4} Pinheiro A.P....Woodside D.B. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family. (PubMed id 18775726)^{1, 2} Dong H....Rao Z. (J. Mol. Biol. 2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)^{1, 2} Grimwood J.... Lucas S.M. (Nature 2004)
Crystallization and preliminary crystallographic analysis of recombinant human calcyphosine. (PubMed id 19275752)¹ Dong H....Bartlam M. (Protein Pept. Lett. 2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (amp 2008)
Prognostic evaluation of epidermal fatty acid-binding protein and calcyphosine, two proteins implicated in endometrial cancer using a proteomic approach. (PubMed id 18729184)¹ Li Z....Zhao X. (Int. J. Cancer 2008)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 828	HGNC: 1487	AceView: CAPSandVMAC	Ensembl:ENSG00000105519	euGenes: HUgn828
ECgene: CAPS	H-InvDB: CAPS

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CAPS	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CAPS gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CAPS gene:
Search GeneIP for patents involving CAPS

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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	EMD Millipore genomic analysis products

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	Browse ELISpot/FluoroSpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Luminex Assays
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Recombinant/Natural Proteins		Browse Stem Cell Products
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for CAPS
	OriGene qPCR primer pairs and template standards for CAPS		OriGene Protein Over-expression Lysate for CAPS
	OriGene MassSpec something-or-other for CAPS		OriGene clones in human, mouse for CAPS
	OriGene qSTAR qPCR primer pairs in human, mouse for CAPS		OriGene Purified Protein for CAPS
	Browse OriGene ORF clones		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for CAPS		OriGene Custom Protein Services for CAPS

	Block miRNA regulation of human, mouse, rat CAPS using miScript Target Protectors		SeqTarget long-range PCR primers for resequencing CAPS
	DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAPS		Predesigned siRNA for gene silencing in human, mouse, rat CAPS
	QuantiFast Probe-based Assays in human, mouse, rat CAPS		QuantiTect SYBR Green Assays in human, mouse, rat CAPS
	Custom PCR Arrays for CAPS		Search Chromatin IP Primers for CAPS
	Pre-validated RT² qPCR Primer Assay in human, mouse / rat CAPS		GeneGlobe Interaction Network for CAPS
	Regulatory tfbs in CAPS promoter

	GenScript Custom Purified and Recombinant Proteins Services for CAPS		GenScript cDNA clones with any tag delivered in your preferred vector for CAPS
	GenScript Custom Assay Services for CAPS		GenScript Custom overexpressing Cell Line Services for CAPS
	CloneReady with Over 120,000 Genes		Gene Synthesis: Any Gene in Any Vector
	Vector-based siRNA and miRNA, Ready for Transfection		Gene Mutant Library, Variants up to 10^11
	Plasmid Preparation		Custom Peptide Services

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Search Tocris compounds for CAPS (CAYP1)

	Browse Sino Biological Proteins
	Browse Sino Biological Cell Lysates
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	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	CAPS antibodies
	CAPS proteins
	CAPS lysates

	Antibodies for CAPS
	See all of Abcam's Antibodies, Kits and Proteins for CAPS
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Recombinant Protein for CAPS

	Proteins for CAPS
	Antibodies for CAPS
	ELISAs for CAPS
	CLIAs for CAPS

Browse ESI BIO Cell Lines and PureStem Progenitors for CAPS

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPS

	SwitchGear 3'UTR luciferase reporter plasmids for CAPS
	SwitchGear Promoter luciferase reporter plasmids for CAPS

Search ThermoFisher Antibodies for CAPS

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPS

	inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CAPS
	inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CAPS

LSBio Antibodies in human, mouse, rat for CAPS

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

Browse compounds at ApexBio

GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes CAPS gene at Home site.

Version: 3.12.136 22 July 2014
hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4

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CAPS Gene

Calcyphosine

Aliases
for CAPS gene

Summaries
for CAPS gene

Genomic Views
for CAPS gene

Proteins
for CAPS gene

CAPS Human Recombinant Protein Products:

CAPS Antibody Products:

CAPS Assay Products:

Domains /
Families
for CAPS gene

Function
for CAPS gene

Localization
for CAPS gene

Pathways & Interactions
for CAPS gene

Drugs & Compounds
for CAPS gene

Transcripts
for CAPS gene

Expression
for CAPS gene

Orthologs
for CAPS gene

Paralogs
for CAPS gene

Genomic Variants
for CAPS gene

Disorders / Diseases
for CAPS gene

Publications
for CAPS gene

External Searches for CAPS gene

Genome Databases showing CAPS gene

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Specialized Databases showing CAPS gene

Intellectual Property
for CAPS gene

Products
for CAPS gene

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Export list of displayed genes

CAPS Gene

Calcyphosine

Aliasesfor CAPS gene

Summariesfor CAPS gene

Genomic Viewsfor CAPS gene

Proteinsfor CAPS gene

CAPS Human Recombinant Protein Products:

CAPS Antibody Products:

CAPS Assay Products:

Domains /Familiesfor CAPS gene

Functionfor CAPS gene

Localizationfor CAPS gene

Pathways & Interactionsfor CAPS gene

Drugs & Compoundsfor CAPS gene

Transcriptsfor CAPS gene

Expression for CAPS gene

Orthologsfor CAPS gene

Paralogsfor CAPS gene

Genomic Variantsfor CAPS gene

Disorders / Diseasesfor CAPS gene

Publicationsfor CAPS gene

External Searches for CAPS gene

Genome Databases showing CAPS gene

Other Databases showing CAPS gene

Specialized Databases showing CAPS gene

Intellectual Propertyfor CAPS gene

Productsfor CAPS gene

View Random Gene

Aliases
for CAPS gene

Summaries
for CAPS gene

Genomic Views
for CAPS gene

Proteins
for CAPS gene

Domains /
Families
for CAPS gene

Function
for CAPS gene

Localization
for CAPS gene

Pathways & Interactions
for CAPS gene

Drugs & Compounds
for CAPS gene

Transcripts
for CAPS gene

Expression
for CAPS gene

Orthologs
for CAPS gene

Paralogs
for CAPS gene

Genomic Variants
for CAPS gene

Disorders / Diseases
for CAPS gene

Publications
for CAPS gene

Intellectual Property
for CAPS gene

Products
for CAPS gene