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CAPRIN2 Gene

protein-coding   GIFtS: 48
GCID: GC12M030862

Caprin Family Member 2

(Previous name: C1q domain containing 1)
(Previous symbol: C1QDC1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Caprin Family Member 21 2     RNA Granule Protein 1402 3
C1QDC11 2 3 5     KIAA18733 5
EEG12 3 5     C1q Domain Containing 11
Cytoplasmic Activation/Proliferation-Associated Protein 22 3     EEG-12
Gastric Cancer Multidrug Resistance-Associated Protein2 3     caprin-22
RNG1402 3     Protein EEG-13
C1q Domain-Containing Protein 12 3     

External Ids:    HGNC: 212591   Entrez Gene: 659812   Ensembl: ENSG000001108887   OMIM: 6103755   UniProtKB: Q6IMN63   

Export aliases for CAPRIN2 gene to outside databases

Previous GC identifers: GC12M030754 GC12M030627


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CAPRIN2 Gene:
The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative
state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis.
Several transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul
2011)

GeneCards Summary for CAPRIN2 Gene:
CAPRIN2 (caprin family member 2) is a protein-coding gene. GO annotations related to this gene include RNA binding and receptor binding. An important paralog of this gene is CBLN2.

UniProtKB/Swiss-Prot: CAPR2_HUMAN, Q6IMN6
Function: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins
involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly
proliferative state towards their terminal phase of differentiation. May be involved in apoptosis

Gene Wiki entry for CAPRIN2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_009714.18  NC_018923.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CAPRIN2
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCAPRIN2 promoter sequence
   Search Chromatin IP Primers for CAPRIN2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAPRIN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11   Ensembl cytogenetic band:  12p11.21   HGNC cytogenetic band: 12p11

CAPRIN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAPRIN2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M030862:  view genomic region     (about GC identifiers)

Start:
30,862,486 bp from pter      End:
30,907,885 bp from pter
Size:
45,400 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CAPR2_HUMAN, Q6IMN6 (See protein sequence)
Recommended Name: Caprin-2  
Size: 1127 amino acids; 125925 Da
Developmental stage: Expression is highly regulated during erythroid development with increased expression at the
stage of differentiation associated with the onset of global nuclear condensation and reduced cell proliferation
Sequence caution: Sequence=AAK83153.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: E4NKG2 Q149P6 Q149P7 Q6IMN5 Q7Z371 Q8TE70 Q8TE71 Q96RN6 Q9H667 Q9HAL4
Alternative splicing: 9 isoforms:  Q6IMN6-1   Q6IMN6-2   Q6IMN6-3   Q6IMN6-4   Q6IMN6-5   Q6IMN6-6   Q6IMN6-7   Q6IMN6-9   
Q6IMN6-10   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CAPRIN2: NX_Q6IMN6

Explore proteomics data for CAPRIN2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CAPRIN2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001002259.1  NP_001193785.1  NP_076414.2  NP_115532.3  

    ENSEMBL proteins: 
     ENSP00000443145   ENSP00000415407   ENSP00000449139   ENSP00000298892   ENSP00000403876  
     ENSP00000379150   ENSP00000391479   ENSP00000438010   ENSP00000444137   ENSP00000440785  
     ENSP00000443353   ENSP00000442295   ENSP00000441005   ENSP00000251071   ENSP00000309785  

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    Novus Biologicals CAPRIN2 Protein
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    Browse Proteins at Cloud-Clone Corp.

     
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    antibodies-online proteins for CAPRIN2 (2 products) 

     
    antibodies-online peptides for CAPRIN2

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    antibodies-online antibodies for CAPRIN2 (18 products) 

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    antibodies-online kits for CAPRIN2 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR022070 Caprin-1_C
     IPR008983 Tumour_necrosis_fac-like_dom
     IPR028816 Caprin
     IPR001073 C1q

    Graphical View of Domain Structure for InterPro Entry Q6IMN6

    ProtoNet protein and cluster: Q6IMN6

    1 Blocks protein domain: IPB001073 Complement C1q protein

    UniProtKB/Swiss-Prot: CAPR2_HUMAN, Q6IMN6
    Similarity: Belongs to the caprin family
    Similarity: Contains 1 C1q domain


    Find genes that share domains with CAPRIN2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAPR2_HUMAN, Q6IMN6
    Function: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins
    involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly
    proliferative state towards their terminal phase of differentiation. May be involved in apoptosis

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003723RNA binding IEA--
    GO:0003824catalytic activity ----
    GO:0005102receptor binding IPI18762581
    GO:0005515protein binding IPI18762581
         
    Find genes that share ontologies with CAPRIN2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CAPRIN2

    miRNA
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    miRTarBase miRNAs that target CAPRIN2:
    hsa-let-7f-5p (MIRT051382), hsa-mir-93-5p (MIRT027968), hsa-mir-124-3p (MIRT002910), hsa-mir-340-5p (MIRT019554)

    Block miRNA regulation of human, mouse, rat CAPRIN2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CAPRIN2 (see all 27):
    hsa-miR-181c hsa-miR-106a hsa-miR-301a hsa-miR-519a hsa-miR-1304 hsa-miR-374c hsa-miR-93 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidCAPRIN2 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CAPR2_HUMAN, Q6IMN6: Isoform 1: Cytoplasm
    CAPR2_HUMAN, Q6IMN6: Isoform 2: Mitochondrion. Cytoplasm. Note=Expressed throughout the cytoplasm
    CAPR2_HUMAN, Q6IMN6: Isoform 5: Mitochondrion. Note=Colocalizes with aggregated mitochondria
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    cytosol2
    nucleus2
    cytoskeleton1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IDA14593112
    GO:0005813centrosome IDA--
    GO:0043235receptor complex IDA18762581

    Find genes that share ontologies with CAPRIN2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CAPRIN2
    Interactions:

        Search GeneGlobe Interaction Network for CAPRIN2

    1 Interacting protein for CAPRIN2 (Q6IMN61) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRP5O751971EBI-6918449,EBI-2466421
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0017148negative regulation of translation IEA--
    GO:0030308negative regulation of cell growth IDA14593112
    GO:0032092positive regulation of protein binding IDA18762581
    GO:0033138positive regulation of peptidyl-serine phosphorylation IDA18762581
    GO:0044237cellular metabolic process ----

    Find genes that share ontologies with CAPRIN2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CAPRIN2 (CAPR2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CAPRIN2 gene (4 alternative transcripts): 
    NM_001002259.2  NM_001206856.2  NM_023925.4  NM_032156.4  

    Unigene Cluster for CAPRIN2:

    Caprin family member 2
    Hs.234355  [show with all ESTs]
    Unigene Representative Sequence: NM_032156
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000537553(uc001rjg.1 uc001rjm.1) ENST00000433722 ENST00000548676
    ENST00000298892(uc001rjh.1) ENST00000454014(uc001rjj.1) ENST00000395805
    ENST00000417045 ENST00000537108 ENST00000553026(uc001rjn.1) ENST00000538387
    ENST00000534897 ENST00000541765 ENST00000543380 ENST00000546129 ENST00000542550
    ENST00000540436 ENST00000540584 ENST00000251071(uc001rjf.1 uc001rjk.4 uc001rji.1 uc001rjl.4)

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CAPRIN2 (see all 27):
    hsa-miR-181c hsa-miR-106a hsa-miR-301a hsa-miR-519a hsa-miR-1304 hsa-miR-374c hsa-miR-93 hsa-miR-526b*
    SwitchGear 3'UTR luciferase reporter plasmidCAPRIN2 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat CAPRIN2

    Additional mRNA sequence: 

    AF326778.1 AF525416.1 AK021453.1 AK026222.1 AL834212.1 AY074490.1 BC007520.1 BC025420.2 
    BC066295.1 BC111007.1 BC117672.1 BC117673.1 BX538080.1 NR_038177.1 

    21 DOTS entries:

    DT.95173435  DT.117389  DT.101984456  DT.95173431  DT.100784670  DT.101984457  DT.100648279  DT.121174684 
    DT.100784678  DT.40108441  DT.101966185  DT.70105353  DT.95076149  DT.121174648  DT.92038217  DT.100711371 
    DT.100784674  DT.100784679  DT.40210376  DT.102832165  DT.95173430 

    Selected AceView cDNA sequences (see all 222):

    AL834212 AA683171 AY074491 BQ010043 BQ007954 AA903168 AI689091 AI540847 
    BF589574 BM693772 AW473992 BK001103 BM706099 BC025420 T23044 F04485 
    BU738211 BM928143 AA403070 BC007520 NM_023925 Z41690 AA497072 NM_001002259 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CAPRIN2 (see all 25)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b · 14c · 14d ^
    SP1:                                                        -                 -                                                                             -   
    SP2:                                                        -                 -                                                                             -   
    SP3:                                                        -                 -                                                                             -   
    SP4:                                                        -                 -                             -                                               -   
    SP5:                                                                                                                                                        -   

    ExUns: 15a · 15b · 15c ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20a · 20b · 20c · 20d ^ 21 ^ 22a · 22b ^ 23 ^ 24 ^ 25 ^ 26a · 26b · 26c
    SP1:                                            -                 -     -     -     -                       -           -               
    SP2:                                            -                 -     -     -     -                       -           -               
    SP3:                                            -     -           -     -     -     -                       -           -               
    SP4:                                            -                 -     -     -     -                       -           -               
    SP5:                                            -                 -     -     -     -                                   -               


    ECgene alternative splicing isoforms for CAPRIN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CAPRIN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CAPRIN2 Expression
    About this image

    CAPRIN2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CAPRIN2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.234355

    UniProtKB/Swiss-Prot: CAPR2_HUMAN, Q6IMN6
    Tissue specificity: Detected in all tissues tested with highest levels of expression in brain and spleen

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPRIN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CAPRIN2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Caprin21 , 5 caprin family member 21, 5 85.33(n)1
    82.38(a)1
      6 (78.62 cM)5
    2325601  NM_181541.31  NP_853519.21 
     1488424925 
    chicken
    (Gallus gallus)
    Aves CAPRIN21 caprin family member 2 73.17(n)
    73.23(a)
      418141  XM_004937902.1  XP_004937959.1 
    lizard
    (Anolis carolinensis)
    Reptilia CAPRIN26
    caprin family member 2
    61(a)
    1 ↔ 1
    5(10826630-10865875)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.37692 Xenopus laevis transcribed sequence with strong similarity more 77.96(n)    BQ384065.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj80b022 Danio rerio cDNA clone IMAGE5411740, partial cds 73.86(n)    BC057503.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Capr6
    Caprin
    20(a)
    1 → many
    3L(18661253-18666260)


    ENSEMBL Gene Tree for CAPRIN2 (if available)
    TreeFam Gene Tree for CAPRIN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CAPRIN2 gene
    CBLN22  C1QL32  CBLN12  C1QTNF32  CAPRIN12  ENSG000002732942  C1QL22  CBLN32  
    C1QL12  CBLN42  C1QL42  
    7 SIMAP similar genes for CAPRIN2 using alignment to 12 protein entries:     CAPR2_HUMAN (see all proteins):
    DKFZp686D159    KIAA1873    CAPRIN1    CBLN2    CBLN1    CBLN4
    CBLN3

    Find genes that share paralogs with CAPRIN2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CAPRIN2 (see all 1092)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs681069411,2
    C--30658573(+) AAAAA-/TTATAA 5 -- int10--------
    rs1393583231,2
    --30729128(+) TTCTCA/TAAGAT 5 -- int10--------
    rs754961871,2
    C,F--30729180(+) TGCCTG/AACCAC 5 -- int13Minor allele frequency- A:0.07CSA WA NA 240
    rs1816266981,2
    --30729279(+) GCCAGC/TAGTAT 5 -- int10--------
    rs792756771,2
    C,F--30729301(+) CTCCTA/GTTGTA 5 -- int12Minor allele frequency- G:0.23CSA WA 120
    rs1122310751,2
    F--30729308(+) TGTATG/ATTACT 5 -- int11Minor allele frequency- A:0.50CSA 2
    rs1454004891,2
    --30729315(+) TACTAC/TACATG 5 -- int10--------
    rs779166111,2
    C,F--30729326(+) TAGTAG/TCTACC 5 -- int11Minor allele frequency- T:0.19WA 118
    rs1488015511,2
    C--30729333(+) TACCCA/GAAGAT 5 -- int10--------
    rs1862481041,2
    --30729405(+) ATTTGA/GCCCAT 5 -- int10--------

    HapMap Linkage Disequilibrium report for CAPRIN2 (30862486 - 30907885 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CAPRIN2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2745706CNV Deletion23290073
    nsv832361CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CAPRIN2
    DNA2.0 Custom Variant and Variant Library Synthesis for CAPRIN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610375    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for CAPRIN2:
    Beckwith-Wiedemann syndrome

    Find genes that share disorders with CAPRIN2           About GenesLikeMe

    Genetic Association Database (GAD): CAPRIN2

    Export disorders for CAPRIN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CAPRIN2 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with CAPRIN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins. (PubMed id 14764709)1, 2, 3 Grill B....Schrader J.W. (J. Immunol. 2004)
    2. RNA granule protein 140 (RNG140), a paralog of RNG105 localized to distinct RNA granules in neuronal dendrites in the adult vertebrate brain. (PubMed id 20516077)1, 2 Shiina N. and Tokunaga M. (J. Biol. Chem. 2010)
    3. Cloning and characterization of a gene expressed during terminal differentiation that encodes a novel inhibitor of growth. (PubMed id 14593112)1, 2 Aerbajinai W.... Miller J.L. (J. Biol. Chem. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    6. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    7. Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation. (PubMed id 18762581)1 Ding Y....Li L. (J. Cell Biol. 2008)
    8. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PubMed id 17903306)4 Newton-Cheh C....Larson M.G. (BMC Med. Genet. 2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 65981 HGNC: 21259 AceView: C1QDC1 Ensembl:ENSG00000110888 euGenes: HUgn65981
    ECgene: CAPRIN2 H-InvDB: CAPRIN2

    (According to HUGE)
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    HUGE: KIAA1873

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CAPRIN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CAPRIN2 gene:
    Search GeneIP for patents involving CAPRIN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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