CAPN8 Gene
protein-coding GIFtS: 45
GCID: GC01M223711
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calpain 8(Previous name: calpain 8 (nCL-2) )
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Aliases
for CAPN8 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Calpain 81 2 | | Calpain 8 (NCL-2)1 | | NCL-21 | | Calpain-81 | | New Calpain 22 3 | | NCL23 | | Stomach-Specific M-Type Calpain2 3 | | EC 3.4.228 | | EC 3.4.22.533 8 | | |
Export aliases for CAPN8 gene to outside databasesPrevious GC identifers: GC02U990107 GC01U901168 GC01M221871 GC01M221782 GC01M194391 |
Summaries
for CAPN8 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CAN8_HUMAN, A6NHC0Function: Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucuscells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein.Proteolytically cleaves the beta-subunit of coatomer complex (By similarity)
 summary
for CAPN8: Calpains are a group of calcium-sensitive cysteine proteases that are ubiquitously expressed in mammals.
This family contains 14 members with mu-calpain (calpain 1) and m-calpain (calpain 2) being the most
well-characterized. Structurally, calpains contain two subunits; an 80 kDa catalytic subunit and a 28 kDa
regulatory subunit that functions as a chaperone to stabilize the 80 kDa structure. Calpains are regulated
by Ca2+ concentration, phosphorylation, calpastatin and probably by altering their subcellular localization
(limiting access to substrate). These endopeptidases have numerous functions including, but not limited to,
remodeling of cytoskeletal attachments to the plasma membrane during cell fusion and cell motility,
proteolytic modification of molecules in signal transduction pathways, degradation of enzymes controlling
progression through the cell cycle, regulation of gene expression, substrate degradation in some apoptotic
pathways, and an involvement in long-term potentiation. Perturbations in calpain activity have been
associated in pathophysiological processes contributing to type II diabetes (calpain 10), Alzheimer's
disease (calpain 1), gastric cancer (calpain 9) and muscular dystrophy (calpain 3).
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Genomic Views
for CAPN8 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CAPN8 gene promoter:
Tal-1 AP-1 Tal-1beta E47 POU2F1 COMP1 POU2F1a LyF-1 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CAPN8
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN8 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q41 Ensembl cytogenetic band: 1q41 HGNC cytogenetic band: 1q41CAPN8 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M223711: view genomic region
(about GC identifiers)
Start:
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223,711,349 bp from pter |
End:
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223,853,436 bp from pter |
Size:
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142,088 bases |
Orientation:
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minus strand |
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Proteins
for CAPN8 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CAN8_HUMAN, A6NHC0 (See
protein sequence)Recommended Name: Calpain-8 Size: 703 amino acids; 79144 Da
Cofactor: Binds 2 calcium ions (Potential)
Subunit: Monomer and homooligomer. Interacts with COPS1/GPS1, COPB1, EYA2, NME2, NME4 and TOMM70A (By similarity)
Subcellular location: Cytoplasm (By similarity). Golgi apparatus (By similarity)
Secondary accessions: B2RXL2Explore the universe of human proteins at neXtProt for CAPN8: NX_A6NHC0
Post-translational modifications:
Undergoes autolytic cleavage between Ala-5 and Ala-6 which gives rise to fragments extending from Ala-6 to theC-terminus, Ala-6 to the EF-hand 2 domain and from Ala-6 to the beginning of domain III (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A6NHC0
4/13 DME Specific Peptides for CAPN8 (A6NHC0) (see all 13)
CAPN8 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001137434.1
ENSEMBL proteins: ENSP00000436371 ENSP00000409233 ENSP00000390294 ENSP00000401665 ENSP00000355838 ENSP00000434013 ENSP00000435953 ENSP00000355837
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CAPN8 for ontologies About GeneDecksing
CAPN8 Antibody Products:
Assay Products for CAPN8: |
Protein
Domains /
Families
for CAPN8 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CAPN8 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry A6NHC0ProtoNet protein and cluster: A6NHC0 UniProtKB/Swiss-Prot: CAN8_HUMAN, A6NHC0Domain: The domain III mediates oligomerization (By similarity)Similarity: Belongs to the peptidase C2 familySimilarity: Contains 1 calpain catalytic domainSimilarity: Contains 3 EF-hand domains |
Function
for CAPN8 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CAN8_HUMAN, A6NHC0Function: Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucuscells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein.Proteolytically cleaves the beta-subunit of coatomer complex (By similarity)Catalytic activity: Broad endopeptidase specificityEnzyme Numbers (IUBMB): EC 3.4.22.531 2 EC 3.4.222
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CAPN8 (NM_001143962) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN8 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN8 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN8 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004198 | calcium-dependent cysteine-type endopeptidase activity |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
CAPN8 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Capn8tm1Hiso for CAPN8
2 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Capn8):
CAPN8 for phenotypes About GeneDecksing
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Pathways & Interactions
for CAPN8 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Tocris Bioscience Pathway for CAPN8
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAPN8
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
IEA | -- |
CAPN8 for ontologies About GeneDecksing
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Drugs & Compounds
for CAPN8 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for CAPN8 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Calpeptin | Calpain and cathepsin L inhibitor | [117591-20-5] | | Acetyl-Calpastatin (184-210) (human) | Selective calpain inhibitor | [123714-50-1] | | MDL 28170 | Potent, selective calpain and cathepsin B inhibitor | [88191-84-8] | | MG 132 | Proteasome and calpain inhibitor. Inhibits NF-kappaB activation | [133407-82-6] | | MG 101 | Calpain inhibitor; activates p53-dependent apoptosis | [110044-82-1] |
1 HMDB Compound for CAPN8 About this table
Search CenterWatch for drugs/clinical trials and news about CAPN8 / CAN8
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Transcripts
for CAPN8 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CAPN8 gene: NM_001143962.1 Unigene Cluster for CAPN8: Calpain 8 Hs.291487 [show with all ESTs]Unigene Representative Sequence: NM_00114396211 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000484873 ENST00000442247 ENST00000430824 ENST00000482401 ENST00000482183
ENST00000419193 ENST00000366873 ENST00000467384 ENST00000465098 ENST00000525760
ENST00000366872(uc009xee.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CAPN8 (NM_001143962) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN8 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN8 |
Additional cDNA sequence: BC157893.1 9 DOTS entries: DT.92417858 DT.206669 DT.97835005 DT.95264161 DT.70104332 DT.75128792 DT.121339980 DT.86845546 DT.86858095 3 AceView cDNA sequences: BM825948 BM759585 BM839499
GeneLoc Exon Structure
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Expression
for CAPN8 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CAPN8 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTCAGCTCT
About this image
See CAPN8 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CAPN8
SOURCE GeneReport for Unigene cluster: Hs.291487
UniProtKB/Swiss-Prot: CAN8_HUMAN, A6NHC0Tissue specificity: Stomach
SABiosciences Custom PCR Arrays for CAPN8
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN8
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAPN8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN8 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN8 |
Orthologs
for CAPN8 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CAPN8 gene from 7/20 species (see all 20) About this table
ENSEMBL Gene Tree for CAPN8 (if available)
TreeFam Gene Tree for CAPN8 (if available) |
Paralogs
for CAPN8 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CAPN8 gene
- CAPN62 CAPN142 CAPN132 CAPN52 CAPN92 CAPN12 CAPN32 CAPN22
- CAPN72 CAPN122 SOLH2 CAPN112 CAPN102
15 SIMAP similar genes for CAPN8 using alignment to 8 protein entries: CAN8_HUMAN (see all proteins):CAPN2 CAPN1 CAPN11 CAPNS2 CAPN3 CAPN9
CAPN12 CAPN14 CAPNS1 CAPN13 CAPN5 SRI
GCA CAPN6 CAPN10
CAPN8 for paralogs About GeneDecksing
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Genomic Variants
for CAPN8 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for CAPN8
3 CNVs: 84863 47889 71318
2 Indels: 24081 44513 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for CAPN8 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CAPN8 for disorders About GeneDecksing
6  diseases for CAPN8: About MalaCardsmuscular dystrophy gastric cancer alzheimer's disease ceroid lipofuscinosis
neuronal ceroid-lipofuscinosis neuronitis
1 disease from the University of Copenhagen DISEASES database for CAPN8:Neuronal ceroid lipofuscinosis Export disorders for CAPN8 gene to outside databases
|
Publications
for CAPN8 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CAPN8 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with CAPN8) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Both the conserved and the unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution. (PubMed id 11523006)1, 2 Hata S.... Suzuki K. (2001)
- Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1, 3 Hillier L.D....Marra M. (1996)
- A novel tissue-specific calpain species expressed predominantly in the stomach comprises two alternative splicing products with and without Ca(2+)-binding domain. (PubMed id 7690035)1, 3 Sorimachi H....Suzuki K. (1993)
- Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains. (PubMed id 17646163)1 Hata S....Sorimachi H. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The calpain family and human disease. (PubMed id 11516996)1 Huang Y. and Wang K.K. (2001)
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External Searches for CAPN8 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CAPN8 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CAPN8 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CAPN8 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CAPN8 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CAPN8 gene:
Search GeneIP for patents involving CAPN8
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CAPN8 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CAPN8 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAPN8 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN8 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CAPN8 | | OriGene 3'-UTR Clone for CAPN8 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN8 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CAPN8 | | OriGene Custom Protein Services for CAPN8 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAPN8 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPN8 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN8 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAPN8 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN8 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN8 |
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 |  |  |  | |
| | | | Tocris compounds for CAPN8 |
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 | | | CAPN8 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN8 |
|  |  |  | | | | Search ThermoFisher Antibodies for CAPN8 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN8 |
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