CAPN7 Gene
protein-coding GIFtS: 57
GCID: GC03P015222
|
|
calpain 7
| |
Aliases
for CAPN7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Calpain 71 2 | | Calpain Like Protease2 | | PALBH2 3 5 | | Calpain-71 | | PalBH1 3 | | Homolog Of Aspergillus Nidulans PALB2 | | PalB Homolog2 3 | | EC 3.4.22.-3 | | CALPAIN72 | | EC 3.4.228 |
Export aliases for CAPN7 gene to outside databasesPrevious GC identifer: GC03P015177 |
Summaries
for CAPN7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CAPN7:
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins areheterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses acysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated inneurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The functionof the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge fromother family members. The mouse orthologue is thought to be calcium independent with protease activity. (provided byRefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CAN7_HUMAN, Q9Y6W3Function: Calcium-regulated non-lysosomal thiol-protease (By similarity)
 summary
for CAPN7: Calpains are a group of calcium-sensitive cysteine proteases that are ubiquitously expressed in mammals.
This family contains 14 members with mu-calpain (calpain 1) and m-calpain (calpain 2) being the most
well-characterized. Structurally, calpains contain two subunits; an 80 kDa catalytic subunit and a 28 kDa
regulatory subunit that functions as a chaperone to stabilize the 80 kDa structure. Calpains are regulated
by Ca2+ concentration, phosphorylation, calpastatin and probably by altering their subcellular localization
(limiting access to substrate). These endopeptidases have numerous functions including, but not limited to,
remodeling of cytoskeletal attachments to the plasma membrane during cell fusion and cell motility,
proteolytic modification of molecules in signal transduction pathways, degradation of enzymes controlling
progression through the cell cycle, regulation of gene expression, substrate degradation in some apoptotic
pathways, and an involvement in long-term potentiation. Perturbations in calpain activity have been
associated in pathophysiological processes contributing to type II diabetes (calpain 10), Alzheimer's
disease (calpain 1), gastric cancer (calpain 9) and muscular dystrophy (calpain 3).
|
Genomic Views
for CAPN7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_022517.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CAPN7 gene promoter:
COUP-TF1 HTF COUP Pax-2 HNF-4alpha2 Pax-2a HNF-4alpha1 YY1 COUP-TF Cart-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CAPN7
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN7 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3p24 Ensembl cytogenetic band: 3p25.1 HGNC cytogenetic band: 3p24CAPN7 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P015222: view genomic region
(about GC identifiers)
Start:
|
15,247,659 bp from pter |
End:
|
15,294,425 bp from pter |
Size:
|
46,767 bases |
Orientation:
|
plus strand |
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Proteins
for CAPN7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CAN7_HUMAN, Q9Y6W3 (See
protein sequence)Recommended Name: Calpain-7 Size: 813 amino acids; 92652 Da
Subcellular location: Nucleus
1 PDB 3D structure from  and Proteopedia  for CAPN7:2QFE (3D)
Explore the universe of human proteins at neXtProt for CAPN7: NX_Q9Y6W3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9Y6W3
2 DME Specific Peptides for CAPN7 (Q9Y6W3)
CAPN7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_055111.1
ENSEMBL proteins: ENSP00000415482 ENSP00000389786 ENSP00000253693 ENSP00000399486 ENSP00000394708
Human Recombinant Protein Products for CAPN7:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CAPN7 for ontologies About GeneDecksing
CAPN7 Antibody Products:
Assay Products for CAPN7: |
Protein
Domains /
Families
for CAPN7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CAPN7 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9Y6W3ProtoNet protein and cluster: Q9Y6W3 1 Blocks protein family: IPB001300 Calpain cysteine protease (C2) family signature
UniProtKB/Swiss-Prot: CAN7_HUMAN, Q9Y6W3Similarity: Belongs to the peptidase C2 familySimilarity: Contains 1 calpain catalytic domain |
Function
for CAPN7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CAN7_HUMAN, Q9Y6W3Function: Calcium-regulated non-lysosomal thiol-protease (By similarity)Catalytic activity: Broad endopeptidase specificity Enzyme Numbers (IUBMB): EC 3.4.222 EC 3.4.22.-1
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004198 | calcium-dependent cysteine-type endopeptidase activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- |
CAPN7 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CAPN7:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Capn7):
CAPN7 for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CAPN7 (NM_014296) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN7 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN7 |
|
Pathways & Interactions
for CAPN7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | DREAM Repression and Dynorphin Expression | | | 2 | Apoptosis Pathway | | | 3 | Integrin Pathway | | | 4 | Rho Family GTPases | | | 5 | Focal Adhesion | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CAPN7
1 Tocris Bioscience Pathway for CAPN7
1  BioSystems Pathway for CAPN7
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAPN7
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for CAPN7 (Q9Y6W32, 3 ENSP000002536934) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
CAPN7 for ontologies About GeneDecksing
|
Drugs & Compounds
for CAPN7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for CAPN7 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Calpeptin | Calpain and cathepsin L inhibitor | [117591-20-5] | | Acetyl-Calpastatin (184-210) (human) | Selective calpain inhibitor | [123714-50-1] | | MDL 28170 | Potent, selective calpain and cathepsin B inhibitor | [88191-84-8] | | MG 132 | Proteasome and calpain inhibitor. Inhibits NF-kappaB activation | [133407-82-6] | | MG 101 | Calpain inhibitor; activates p53-dependent apoptosis | [110044-82-1] |
1 HMDB Compound for CAPN7 About this table
Search CenterWatch for drugs/clinical trials and news about CAPN7 / CAN7
|
Transcripts
for CAPN7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CAPN7 gene: NM_014296.2 Unigene Cluster for CAPN7: Calpain 7 Hs.595234 [show with all ESTs]Unigene Representative Sequence: NM_0142967 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000418994 ENST00000457023 ENST00000253693(uc003bzn.3) ENST00000415565
ENST00000443567 ENST00000463417 ENST00000472400
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CAPN7 (NM_014296) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN7 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN7 |
Additional cDNA sequence: AB028639.1 AK093742.1 AK314253.1 BC056202.1 8 DOTS entries: DT.447313 DT.40290519 DT.95163604 DT.100777683 DT.120881922 DT.75108215 DT.95192597 DT.75111990 24/152 AceView cDNA sequences (see all 152): BQ695201 AA283709 BU733879 BQ771520 AA306166 NM_014296 BX489747 BM709831 AA810513 CK819822 AI281635 AA327871 BE349584 CA944664 CA414691 AI262857 AW874050 Z45756 BM542920 AK093742 AW102566 BM141999 AI139178 AA371043
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CAPN7 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21 | ^ | 22a | · |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 22b | · | 22c |
|---|
|
| SP1: | | | | | |
| SP2: | | | | | |
| SP3: | | | | | |
| SP4: | | | | | |
| SP5: | | | | |
ECgene alternative splicing isoforms for CAPN7
|
Expression
for CAPN7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CAPN7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAAATTCCCA
About this image
See CAPN7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CAPN7
SOURCE GeneReport for Unigene cluster: Hs.595234
UniProtKB/Swiss-Prot: CAN7_HUMAN, Q9Y6W3Tissue specificity: Ubiquitous
SABiosciences Expression via Pathway-Focused PCR Array including CAPN7:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN7
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAPN7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN7 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN7 |
Orthologs
for CAPN7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CAPN7 gene from 6/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CAPN71 |
calpain 7 |
79.19(n)
83.74(a) |
|
420683 XM_418783.3 XP_418783.2 |
lizard
(Anolis carolinensis) |
Reptilia |
CAPN76 |
-- |
84(a) |
1 ↔ 1 |
6(36574448-36603520) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.157452 |
Xenopus laevis transcribed sequence with moderate similarity more |
74.23(n) |
|
BJ091178.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
capn71 |
calpain 7 |
70.44(n)
77.24(a) |
|
556792 NM_001135108.1 NP_001128580.1 |
mosquito
(Anopheles gambiae) |
Insecta |
AgaP_AGAP0108341 |
AGAP010834-PA |
51.99(n)
51.28(a) |
|
1271128 XM_309874.4 XP_309874.4 |
worm
(Caenorhabditis elegans) |
Secernentea |
clp-21 , 3 |
Calpain thiol protease3
Protein CLP-21 |
41(a)3
52.25(n)1
43.77(a)1 |
|
III(4772238-4775805)3
1756181 NM_065563.21 NP_497964.11 |
ENSEMBL Gene Tree for CAPN7 (if available)
TreeFam Gene Tree for CAPN7 (if available) |
Paralogs
for CAPN7 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CAPN7 gene
- CAPN62 CAPN82 CAPN142 CAPN132 CAPN52 CAPN92 CAPN12 CAPN32
- CAPN22 CAPN122 SOLH2 CAPN112 CAPN102
CAPN7 for paralogs About GeneDecksing
|
Genomic Variants
for CAPN7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CAPN7 (15247659 - 15294425 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CAPN7
1 CNV: 6162
1 Indel: 98242 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CAPN7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CAPN7 for disorders About GeneDecksing
OMIM gene information: 606400
OMIM disorders: --
4  diseases for CAPN7: About MalaCardsmuscular dystrophy gastric cancer alzheimer's disease malaria
Export disorders for CAPN7 gene to outside databases
|
Publications
for CAPN7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CAPN7 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with CAPN7) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning of PalBH, a mammalian homologue of the Aspergillus atypical calpain PalB. (PubMed id 11342116)1, 2, 9 Futai E.... Maeda T. (2001)
- Capn7: a highly divergent vertebrate calpain with a novel C-terminal domain. (PubMed id 10051333)1, 3 Franz T....Dear T.N. (1999)
- New era of calpain research. Discovery of tissue-specific calpains. (PubMed id 8163008)1, 3 Sorimachi H....Suzuki K. (1994)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Calpain-7 binds to CHMP1B at its second a-helical regi on and forms a ternary complex with IST1. (PubMed id 21616915)1 Maemoto Y....Maki M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT-MIM interaction. (PubMed id 20849418)1 Osako Y....Maki M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A yeast two-hybrid system reconstituting substrate recognition of the von Hippel-Lindau tumor suppressor protein. (PubMed id 17986458)1 Bex C....Buchberger A. (2007)
|
External Searches for CAPN7 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CAPN7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CAPN7 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CAPN7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CAPN7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CAPN7 gene:
Search GeneIP for patents involving CAPN7
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CAPN7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CAPN7 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAPN7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN7 | | | OriGene Protein Over-expression Lysate for CAPN7 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CAPN7 | | OriGene 3'-UTR Clone for CAPN7 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN7 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CAPN7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CAPN7 | | OriGene Custom Protein Services for CAPN7 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAPN7 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPN7 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN7 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAPN7 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN7 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN7 |
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| | | | Tocris compounds for CAPN7 |
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 | | | CAPN7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN7 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CAPN7 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN7 |
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