CAPN13 Gene
protein-coding GIFtS: 51
GCID: GC02M030945
|
|
calpain 13
| |
Aliases
for CAPN13 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Calpain 131 2 | | Calcium-Activated Neutral Proteinase 132 3 | | CANP 132 3 | | FLJ235231 | | Calpain-131 | | EC 3.4.22.-3 |
Export aliases for CAPN13 gene to outside databasesPrevious GC identifers: GC02M030860 GC02M031061 GC02M030938 GC00U916966 GC02M030857 GC02M030799 GC02M030683 |
Summaries
for CAPN13 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CAPN13:
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammaliancalpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist ofheterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This geneencodes a member of the calpain large subunit family. (provided by RefSeq, Jun 2012)
UniProtKB/Swiss-Prot: CAN13_HUMAN, Q6MZZ7Function: Probable non-lysosomal thiol-protease (By similarity)
 summary
for CAPN13: Calpains are a group of calcium-sensitive cysteine proteases that are ubiquitously expressed in mammals.
This family contains 14 members with mu-calpain (calpain 1) and m-calpain (calpain 2) being the most
well-characterized. Structurally, calpains contain two subunits; an 80 kDa catalytic subunit and a 28 kDa
regulatory subunit that functions as a chaperone to stabilize the 80 kDa structure. Calpains are regulated
by Ca2+ concentration, phosphorylation, calpastatin and probably by altering their subcellular localization
(limiting access to substrate). These endopeptidases have numerous functions including, but not limited to,
remodeling of cytoskeletal attachments to the plasma membrane during cell fusion and cell motility,
proteolytic modification of molecules in signal transduction pathways, degradation of enzymes controlling
progression through the cell cycle, regulation of gene expression, substrate degradation in some apoptotic
pathways, and an involvement in long-term potentiation. Perturbations in calpain activity have been
associated in pathophysiological processes contributing to type II diabetes (calpain 10), Alzheimer's
disease (calpain 1), gastric cancer (calpain 9) and muscular dystrophy (calpain 3).
|
Genomic Views
for CAPN13 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_022184.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CAPN13 gene promoter:
NF-1 ATF-2 STAT5A c-Ets-1 HNF-1A E2F E2F-1 POU2F1 HNF-1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CAPN13
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN13 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2p22-p21 Ensembl cytogenetic band: 2p23.1 HGNC cytogenetic band: 2p22-p21CAPN13 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M030945: view genomic region
(about GC identifiers)
Start:
|
30,945,637 bp from pter |
End:
|
31,043,408 bp from pter |
Size:
|
97,772 bases |
Orientation:
|
minus strand |
|
Proteins
for CAPN13 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CAN13_HUMAN, Q6MZZ7 (See
protein sequence)Recommended Name: Calpain-13 Size: 669 amino acids; 76696 Da
Caution: It is unlikely that this protein binds calcium as none of the 2 EF-hand domains seem to contain a canonicalcalcium-binding site
1 PDB 3D structure from  and Proteopedia  for CAPN13:2I7A (3D)
Secondary accessions: Q17RF0 Q580X1 Q8TE80Alternative splicing: 2 isoforms: Q6MZZ7-1 Q6MZZ7-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CAPN13: NX_Q6MZZ7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6MZZ7
CAPN13 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_653176.2
ENSEMBL proteins: ENSP00000403180 ENSP00000295055 ENSP00000416191 ENSP00000440723 ENSP00000431298
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
IEA | -- |
CAPN13 for ontologies About GeneDecksing
CAPN13 Antibody Products:
Assay Products for CAPN13: |
Protein
Domains /
Families
for CAPN13 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CAPN13 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6MZZ7ProtoNet protein and cluster: Q6MZZ7 1 Blocks protein family: IPB001300 Calpain cysteine protease (C2) family signature
UniProtKB/Swiss-Prot: CAN13_HUMAN, Q6MZZ7Similarity: Belongs to the peptidase C2 familySimilarity: Contains 1 calpain catalytic domainSimilarity: Contains 2 EF-hand domains |
Function
for CAPN13 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CAN13_HUMAN, Q6MZZ7Function: Probable non-lysosomal thiol-protease (By similarity)Enzyme Number (IUBMB): EC 3.4.22.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CAPN13 (NM_144575) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN13 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN13 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN13 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004198 | calcium-dependent cysteine-type endopeptidase activity |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
CAPN13 for ontologies About GeneDecksing
|
Pathways & Interactions
for CAPN13 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Tocris Bioscience Pathway for CAPN13
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAPN13
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for CAPN13 (ENSP000002950554) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
IEA | -- |
CAPN13 for ontologies About GeneDecksing
|
Drugs & Compounds
for CAPN13 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for CAPN13 available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Calpeptin | Calpain and cathepsin L inhibitor | [117591-20-5] | | Acetyl-Calpastatin (184-210) (human) | Selective calpain inhibitor | [123714-50-1] | | MDL 28170 | Potent, selective calpain and cathepsin B inhibitor | [88191-84-8] | | MG 132 | Proteasome and calpain inhibitor. Inhibits NF-kappaB activation | [133407-82-6] | | MG 101 | Calpain inhibitor; activates p53-dependent apoptosis | [110044-82-1] |
1 HMDB Compound for CAPN13 About this table
Search CenterWatch for drugs/clinical trials and news about CAPN13 / CAN13
|
Transcripts
for CAPN13 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CAPN13 gene: NM_144575.2 Unigene Cluster for CAPN13: Calpain 13 Hs.660911 [show with all ESTs]Unigene Representative Sequence: BX6476788 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000450650(uc002rnm.3) ENST00000295055(uc021vfn.1 uc021vfm.1)
ENST00000490786 ENST00000458085(uc002rno.3 uc002rnp.1) ENST00000465450
ENST00000465960 ENST00000485248 ENST00000534090
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CAPN13 (NM_144575) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CAPN13 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN13 |
Additional cDNA sequence: AK026692.1 AK027176.1 AK074418.1 AK290298.1 AK308037.1 BC117345.1 BC117347.1 BX640793.1 BX647678.1 4 DOTS entries: DT.100018100 DT.97834587 DT.99965032 DT.75106867 24/51 AceView cDNA sequences (see all 51): AI821843 BM975637 BF509997 AW088283 NM_144575 AW295620 BM975419 AI687048 AI868165 AI821097 BF509494 BU688648 AI554394 AI682008 AK074418 CB850799 BM127385 BU579691 BF222311 AI762355 AW006402 AA554255 BQ130549 BM127691
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CAPN13 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | |
| ExUns: | 22 | ^ | 23 |
|---|
|
| SP1: | | | | | |
| SP2: | | | | | |
| SP3: | | | | | |
| SP4: | | | | | |
| SP5: | | | | |
ECgene alternative splicing isoforms for CAPN13
|
Expression
for CAPN13 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CAPN13 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATCTGCAA
About this image
See CAPN13 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CAPN13
SOURCE GeneReport for Unigene cluster: Hs.660911
UniProtKB/Swiss-Prot: CAN13_HUMAN, Q6MZZ7Tissue specificity: Weakly expressed in lung and testis. Weakly or not expressed in other tissues
SABiosciences Custom PCR Arrays for CAPN13
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN13
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAPN13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN13 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN13 |
Orthologs
for CAPN13 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CAPN13 gene from 5/15 species (see all 15) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CAPN131 |
calpain 13 |
55.64(n)
45.21(a) |
|
421304 XM_419369.3 XP_419369.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CAPN136 |
-- |
36(a) |
1 ↔ 1 |
1(250013064-250111113) |
zebrafish
(Danio rerio) |
Actinopterygii |
capn126 |
calpain 12 |
26(a) |
possible ortholog |
18(35004491-35073668) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATDEK16 |
calpain-type cysteine protease |
5(a) |
1 → many |
1(20653820-20665095) |
rice
(Oryza sativa) |
Liliopsida |
-- |
calpain, putative, expressed |
5(a) |
1 → many |
2(29335385-29352022) |
ENSEMBL Gene Tree for CAPN13 (if available)
TreeFam Gene Tree for CAPN13 (if available) |
Paralogs
for CAPN13 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CAPN13 gene
- CAPN62 CAPN82 CAPN142 CAPN52 CAPN92 CAPN12 CAPN32 CAPN22
- CAPN72 CAPN122 SOLH2 CAPN112 CAPN102
8 SIMAP similar genes for CAPN13 using alignment to 4 protein entries: CAN13_HUMAN (see all proteins):CAPNS1 CAPN8 CAPN1 CAPN14 CAPN11 CAPN9
CAPN2 CAPN3
CAPN13 for paralogs About GeneDecksing
|
Genomic Variants
for CAPN13 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CAPN13 (30945637 - 31043408 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CAPN13
1 Indel: 60293
Human Gene Mutation Database (HGMD): CAPN13
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPN13 |
|
Disorders
/ Diseases
for CAPN13 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CAPN13 for disorders About GeneDecksing
OMIM gene information: 610228
OMIM disorders: --
7  diseases for CAPN13: About MalaCardsmuscular dystrophy limb-girdle muscular dystrophy gastric cancer alzheimer's disease
neurodegeneration hypertension neuronitis
Human Genome Epidemiology (HuGE) Navigator: CAPN13 (2 documents)
Export disorders for CAPN13 gene to outside databases
|
Publications
for CAPN13 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CAPN13 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CAPN13) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characterization of two novel calpain large subunit genes. (PubMed id 11675017)1, 2, 3 Dear T.N. and Boehm T. (2001)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Gene-environment interaction for hypertension among A frican American women across generations. (PubMed id 20591971)1 Taylor J.Y....Kardia S.L. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
- Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family. (PubMed id 10964513)1 Dear T.N....Boehm T. (2000)
|
External Searches for CAPN13 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CAPN13 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CAPN13 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CAPN13 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CAPN13 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CAPN13 gene:
Search GeneIP for patents involving CAPN13
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CAPN13 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAPN13 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAPN13 | | | OriGene Protein Over-expression Lysate for CAPN13 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CAPN13 | | OriGene 3'-UTR Clone for CAPN13 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAPN13 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CAPN13 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CAPN13 | | OriGene Custom Protein Services for CAPN13 | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAPN13 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAPN13 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAPN13 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAPN13 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAPN13 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAPN13 |
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 | | | CAPN13 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAPN13 |
|  |  |  | | | | Search ThermoFisher Antibodies for CAPN13 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAPN13 |
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