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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CAP2 Gene

protein-coding   GIFtS: 56
GCID: GC06P017393

CAP, adenylate cyclase-associated protein, 2 (yeast)
 Explore 2 diseases affiliated with
CAP2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CAP2    

Aliases
for CAP2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
CAP, Adenylate Cyclase-Associated Protein, 2 (Yeast)1 2
CAP 22 3
2810452G09Rik2
Adenylyl Cyclase-Associated Protein 22
PI85
SERPINB85

External Ids:    HGNC: 200391   Entrez Gene: 104862   Ensembl: ENSG000001121867   OMIM: 6016975   UniProtKB: P401233   

Export aliases for CAP2 gene to outside databases

Previous GC identifers: GC06P017451 GC06P017501 GC06P017340


Summaries
for CAP2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CAP2:
This gene was identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of
the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl
cyclase-associated protein and actin. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CAP2_HUMAN, P40123
Function: May have a regulatory bifunctional role

Gene Wiki entry for CAP2


Genomic Views
for CAP2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CAP2 gene promoter:
         ATF-2   E4BP4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CAP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CAP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.3   Ensembl cytogenetic band:  6p22.3   HGNC cytogenetic band: 6p22.3

CAP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAP2 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P017393:  view genomic region     (about GC identifiers)

Start:
 17,393,447 bp from pter      End:
 17,558,023 bp from pter
Size:
 164,577 bases      Orientation:
 plus strand

Proteins
for CAP2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CAP2_HUMAN, P40123 (See protein sequence)
Recommended Name: Adenylyl cyclase-associated protein 2  
Size: 477 amino acids; 52824 Da
Subcellular location: Cell membrane; Peripheral membrane protein (By similarity)
Secondary accessions: B2R5Y3 Q6IAY2

Explore the universe of human proteins at neXtProt for CAP2: NX_P40123

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P40123

    • CAP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006357.1  
    ENSEMBL proteins: 
     ENSP00000229922   ENSP00000417705   ENSP00000368275   ENSP00000417208   ENSP00000420615  
     ENSP00000418604   ENSP00000419906  
    Reactome Protein details: P40123
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: CAP2
    OriGene Protein Over-expression Lysate: CAP2
    OriGene Custom Protein Services for CAP2 
    GenScript Custom Purified and Recombinant Proteins Services for CAP2
    Novus Biologicals CAP2 Protein
    Novus Biologicals CAP2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CAP2

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--


    CAP2 for ontologies           About GeneDecksing



    CAP2 Antibody Products: 
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    Abcam antibodies for CAP2 
    Uscn Antibodies for CAP2
    Search ThermoFisher Antibodies for CAP2

    Assay Products for CAP2: 
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    Uscn ELISAs and CLIAs for CAP2

    Protein Domains /
    Families
    for CAP2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CAP2 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR001837 Adenylate_cyclase-assoc_CAP
     IPR013992 Adenylate_cyclase-assoc_CAP_N
     IPR017901 C-CAP_CF_C-like
     IPR016098 CAP/MinC_C
     IPR018106 CAP_CS

    Graphical View of Domain Structure for InterPro Entry P40123

    ProtoNet protein and cluster: P40123

    2 Blocks protein families:
    IPB001837 CAP protein
    IPB006599 Cyclase-associated protein


    UniProtKB/Swiss-Prot: CAP2_HUMAN, P40123
    Similarity: Belongs to the CAP family
    Similarity: Contains 1 C-CAP/cofactor C-like domain


    Function
    for CAP2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CAP2_HUMAN, P40123
    Function: May have a regulatory bifunctional role

    miRNA
    Products:            		 OriGene 3'-UTR Clone: CAP2
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CAP2
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate CAP2 (see all 9):
    hsa-miR-3910 hsa-miR-548p hsa-miR-135b hsa-miR-582-5p hsa-miR-2276 hsa-miR-15b* hsa-miR-3119 hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmid: CAP2 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAP2 (see all 7)
    OriGene shRNA RFP: CAP2
    OriGene siRNA: CAP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAP2

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CAP2

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAP2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CAP2 (NM_006366)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAP2 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CAP2
    Search LifeMap BioReagents cell lines for CAP2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAP2

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--


    CAP2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for CAP2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Axon guidance
    		Axon guidance1.00
    		Developmental Biology0.69
    2Role of Abl in Robo-Slit signaling
    		Role of Abl in Robo-Slit signaling1.00
    3Activation of Rac
    		Signaling by Robo receptor0.44

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for CAP2
        Developmental Biology
    Role of Abl in Robo-Slit signaling
    Signaling by Robo receptor
    Axon guidance



    CAP2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/87 Interacting proteins for CAP2 (P401232, 3 ENSP000002299224) via UniProtKB, MINT, STRING, and/or I2D (see all 87)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRPF40AO754002, 3MINT-61869 I2D: score=3 
    YWHAEP622583, ENSP000002643354I2D: score=3 STRING: ENSP00000264335
    PSPHP783303, ENSP000002756054I2D: score=1 STRING: ENSP00000275605
    ACTG1P632613, ENSP000003315144I2D: score=9 STRING: ENSP00000331514
    CAP1Q015183, ENSP000003618784I2D: score=3 STRING: ENSP00000361878
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000902cell morphogenesis ----
    GO:0007010cytoskeleton organization IEA--
    GO:0007163establishment or maintenance of cell polarity TAS7962207
    GO:0007165signal transduction TAS7962207
    GO:0007190activation of adenylate cyclase activity TAS7962207


    CAP2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CAP2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CAP2
    Search CenterWatch for drugs/clinical trials and news about CAP2 

    Transcripts
    for CAP2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CAP2 gene: 
    NM_006366.2  

    Unigene Cluster for CAP2:

    CAP, adenylate cyclase-associated protein, 2 (yeast)
    Hs.132902  [show with all ESTs]
    Unigene Representative Sequence: NM_006366
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000229922(uc010jpk.1 uc003ncb.3 uc011dja.2 uc011djb.2 uc011djc.2 uc011djd.2)
    ENST00000489374 ENST00000378990 ENST00000493172 ENST00000479291 ENST00000465994
    ENST00000476263

    miRNA
    Products:             		 OriGene 3'-UTR Clone: CAP2
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CAP2
    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate CAP2 (see all 9):
    hsa-miR-3910 hsa-miR-548p hsa-miR-135b hsa-miR-582-5p hsa-miR-2276 hsa-miR-15b* hsa-miR-3119 hsa-miR-205*
    SwitchGear 3'UTR luciferase reporter plasmid: CAP2 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CAP2 (see all 7)
    OriGene shRNA RFP: CAP2
    OriGene siRNA: CAP2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAP2
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CAP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CAP2
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CAP2 (NM_006366)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAP2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAP2 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CAP2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAP2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAP2

    Additional cDNA sequence: 

    AK293134.1 AK294215.1 AK295600.1 AK297538.1 AK308461.1 AK312362.1 AL832154.1 BC008481.1 
    CR457022.1 U02390.1 

    10 DOTS entries:

    DT.115804  DT.92442448  DT.101979588  DT.95108858  DT.121380640  DT.86837933  DT.95327992  DT.100660316 
    DT.100787999  DT.100788002 

    24/232 AceView cDNA sequences (see all 232):

    AA329549 AU123318 BE217938 BP361898 BM712984 W25362 CD673241 BU734637 
    NM_006366 AI468733 BE670582 F28199 AW130810 AA031399 BM676168 AV727249 
    AI754419 AI671183 AA045806 BQ024464 AW444984 BU508073 AW170782 R76800 

    GeneLoc Exon Structure


    Expression
    for CAP2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CAP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TACCAAGGTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CAP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Skeletal MuscleHyoid Arch MusclesMononuclear MyocytesSkeletal Muscle
    Skeletal MuscleMandibular Arch MusclesMononuclear MyocytesSkeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 5 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E68 (Embryonic Progenitor Cell)
    PureStem™ progenitor T42 (Embryonic Progenitor Cell)
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)
    PureStem™ progenitor U31 (Embryonic Progenitor Cell)

    See CAP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CAP2

    SOURCE GeneReport for Unigene cluster: Hs.132902
        SABiosciences Custom PCR Arrays for CAP2
    Primer
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAP2

    Orthologs
    for CAP2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CAP2 gene from 9/27 species (see all 27)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cap21 , 5 CAP, adenylate cyclase-associated protein, 2 (yeast)1, 5 85.08(n)1
    89.08(a)1    		   13 (23.83 cM)5
    672521  NM_026056.41  NP_080332.11 
     465018485 
    chicken
    (Gallus gallus)    		 Aves CAP21 CAP, adenylate cyclase-associated protein, 2 (yeast) 76.12(n)
    81.51(a)    		   420847  XM_418936.3  XP_418936.2 
    lizard
    (Anolis carolinensis)    		 Reptilia CAP26
    		 --
    		 76(a)
    		 1 ↔ 1
    		 4(59046324-59085227)
    zebrafish
    (Danio rerio)    		 Actinopterygii BC060935.12   -- 73.33(n)   393809  BC060935.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta capt3 actin filament organization actin binding 48(a)   21F2   --
    worm
    (Caenorhabditis elegans)    		 Secernentea F41G4.2a3 adenylyl cyclase-associated protein 46(a)
    (best of 4)    		   X(16838477-16844453)   --
    A. gossypii yeast
    (Ashbya gossypii)    		 Saccharomycetes AGOS_AFR061W1 AFR061Wp 44.74(n)
    35.53(a)    		   4621849  NM_210962.1  NP_985608.1 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ATCAP16
    		 cyclase associated protein 1
    		 35(a)
    		 1 → many
    		 4(16484530-16487417)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 adenylyl cyclase-associated protein, putative, exp...
    adenylyl cyclase-associated protein, putative, exp...
    		 33(a)
    31(a)
    		 many ↔ many
    many ↔ many
    		 8(21866594-21871064)
    3(29308849-29313811)


    ENSEMBL Gene Tree for CAP2 (if available)
    TreeFam Gene Tree for CAP2 (if available) 

    Paralogs
    for CAP2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CAP2 gene
    CAP12  
    2 SIMAP similar genes for CAP2 using alignment to 7 protein entries:     CAP2_HUMAN (see all proteins):
    DKFZp686D0714    CAP1

    CAP2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CAP2
    PGOHUM00000247881


    Genomic Variants
    for CAP2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2959 NCBI SNPs in CAP2 are shown (see all 2959)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs9749481,2
    		C,A,H,--17391759(+) GTCCAA/GTTGGA 1 -- us2k110Minor allele frequency- G:0.49MN WA NA CSA EA 551
    rs1846789831,2
    		--17391773(+) TATGGA/GCAATA 1 -- us2k10--------
    rs9749491,2
    		C,F,A,H,--17391785(+) GTATCA/CAAGAG 1 -- us2k119Minor allele frequency- C:0.21MN NS EA WA NA CSA 2514
    rs766853921,2
    		C,F,--17391905(+) GGCTCG/ATTACT 1 -- us2k11Minor allele frequency- A:0.06WA 118
    rs1408210921,2
    		--17391949(+) GATTTC/TCCTGC 1 -- us2k10--------
    rs119651991,2
    		C,F,A,H,--17391992(+) CCAAAC/TTAACC 1 -- us2k19Minor allele frequency- T:0.41NA WA CSA EA 368
    rs119683121,2
    		C,F,H,--17391999(+) AACCAT/CTGCTA 1 -- us2k16Minor allele frequency- C:0.49NA WA CSA 127
    rs21434471,2
    		C,F,A,--17392039(+) TCCCCC/AAGTGC 1 -- us2k19Minor allele frequency- A:0.20NA WA CSA EA 370
    rs1899493731,2
    		--17392098(+) CAGCCA/GGGGCC 1 -- us2k10--------
    rs69374631,2
    		C,F,A,--17392147(+) TCCAGC/GTAAAC 1 -- us2k18Minor allele frequency- G:0.19WA NA CSA EA 368

    HapMap Linkage Disequilibrium report for CAP2 (17393447 - 17558023 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 14 variations for CAP2
         6 CNVs: 93511 64440 44243 99439 6480 93510
         8 Indels: 28227 28226 93512 99440 42824 62477 47075 40836

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CAP2
    DNA2.0 Custom Variant and Variant Library Synthesis for CAP2

    Disorders / Diseases
    for CAP2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CAP2 for disorders           About GeneDecksing

    OMIM gene information: 601697    OMIM disorders: --

    2 diseases for CAP2:    About MalaCards
    tongue cancer    malaria


    Export disorders for CAP2 gene to outside databases

    Publications
    for CAP2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CAP2 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with CAP2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Comparison of human CAP and CAP2, homologs of the yeast adenylyl cyclase-associated proteins. (PubMed id 7962207)1, 2, 3, 9 Yu G.... Young D. (1994)
    2. Mammalian CAP interacts with CAP, CAP2, and actin. (PubMed id 8761950)1, 3, 9 Hubberstey A....Young D. (1996)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Overexpression of cyclase-associated protein 2 in multistage hepatocarcinogenesis. (PubMed id 17000669)1, 9 Shibata R....Sakamoto M. (2006)
    5. Involvement of hepatocellular carcinoma biomarker, cyc lase-associated protein 2 in zebrafish body development and cancer progression. (PubMed id 23022774)1 Effendi K....Sakamoto M. (2013)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (2010)
    10. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1 Gudbjartsson D.F....Stefansson K. (2008)

    External Searches for CAP2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing CAP2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10486 HGNC: 20039 AceView: CAP2 Ensembl:ENSG00000112186 euGenes: HUgn10486
    ECgene: CAP2 H-InvDB: CAP2

    Other Databases showing CAP2 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CAP2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CAP2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CAP2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CAP2 gene:
    Search GeneIP for patents involving CAP2

    GeneCards and IP:
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