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Aliases for CAMTA2 Gene

Aliases for CAMTA2 Gene

  • Calmodulin Binding Transcription Activator 2 2 3
  • KIAA0909 4 6

External Ids for CAMTA2 Gene

Previous GeneCards Identifiers for CAMTA2 Gene

  • GC17M005290
  • GC17M004816
  • GC17M005071
  • GC17M004812
  • GC17M004871

Summaries for CAMTA2 Gene

Entrez Gene Summary for CAMTA2 Gene

  • The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmodulin-binding domain. The encoded protein may be a transcriptional coactivator of genes involved in cardiac growth. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]

GeneCards Summary for CAMTA2 Gene

CAMTA2 (Calmodulin Binding Transcription Activator 2) is a Protein Coding gene. Diseases associated with CAMTA2 include muscle hypertrophy. GO annotations related to this gene include chromatin binding and histone deacetylase binding. An important paralog of this gene is CAMTA1.

UniProtKB/Swiss-Prot for CAMTA2 Gene

  • Transcription activator. May act as tumor suppressor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CAMTA2 Gene

Genomics for CAMTA2 Gene

Regulatory Elements for CAMTA2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CAMTA2 Gene

4,967,992 bp from pter
4,987,673 bp from pter
19,682 bases
Minus strand

Genomic View for CAMTA2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CAMTA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CAMTA2 Gene

Proteins for CAMTA2 Gene

  • Protein details for CAMTA2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Calmodulin-binding transcription activator 2
    Protein Accession:
    Secondary Accessions:
    • B9EGL0
    • D3DTL5
    • E7EWU5
    • Q7Z6M8
    • Q8N3V0
    • Q8NDG4
    • Q96G17

    Protein attributes for CAMTA2 Gene

    1202 amino acids
    Molecular mass:
    131530 Da
    Quaternary structure:
    • May interact with calmodulin.
    • Sequence=AAH16163.1; Type=Frameshift; Positions=865; Evidence={ECO:0000305}; Sequence=BAA74932.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for CAMTA2 Gene

neXtProt entry for CAMTA2 Gene

Proteomics data for CAMTA2 Gene at MOPED

Post-translational modifications for CAMTA2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CAMTA2 Gene

Domains for CAMTA2 Gene

Protein Domains for CAMTA2 Gene

Graphical View of Domain Structure for InterPro Entry



  • O94983
  • Contains 1 CG-1 DNA-binding domain.
  • Contains 1 IPT/TIG domain.
  • Contains 2 IQ domains.
  • Belongs to the CAMTA family.
  • Contains 3 ANK repeats.
genes like me logo Genes that share domains with CAMTA2: view

No data available for Gene Families for CAMTA2 Gene

Function for CAMTA2 Gene

Molecular function for CAMTA2 Gene

UniProtKB/Swiss-Prot Function: Transcription activator. May act as tumor suppressor.

Gene Ontology (GO) - Molecular Function for CAMTA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IDA 16678093
GO:0005515 protein binding IPI 16678093
GO:0008134 transcription factor binding IGI 16678093
GO:0042826 histone deacetylase binding IDA 16678093
genes like me logo Genes that share ontologies with CAMTA2: view

Phenotypes for CAMTA2 Gene

MGI mutant phenotypes for CAMTA2:
inferred from 1 alleles
GenomeRNAi human phenotypes for CAMTA2:
genes like me logo Genes that share phenotypes with CAMTA2: view

Animal Models for CAMTA2 Gene

MGI Knock Outs for CAMTA2:

Animal Model Products

CRISPR Products

miRNA for CAMTA2 Gene

miRTarBase miRNAs that target CAMTA2

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CAMTA2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for CAMTA2 Gene

Localization for CAMTA2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CAMTA2 Gene

Subcellular locations from

Jensen Localization Image for CAMTA2 Gene COMPARTMENTS Subcellular localization image for CAMTA2 gene
Compartment Confidence
nucleus 5
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CAMTA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 16678093
genes like me logo Genes that share ontologies with CAMTA2: view

Pathways for CAMTA2 Gene

SuperPathways for CAMTA2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CAMTA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IDA 16678093
GO:0014898 cardiac muscle hypertrophy in response to stress IDA 16678093
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IGI 16678093
genes like me logo Genes that share ontologies with CAMTA2: view

No data available for Pathways by source for CAMTA2 Gene

Transcripts for CAMTA2 Gene

Unigene Clusters for CAMTA2 Gene

Calmodulin binding transcription activator 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CAMTA2

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CAMTA2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CAMTA2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b ^ 20a · 20b ^ 21a · 21b ^
SP1: - - -
SP2: -
SP5: -

ExUns: 22a · 22b · 22c

Relevant External Links for CAMTA2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CAMTA2 Gene

mRNA expression in normal human tissues for CAMTA2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CAMTA2 Gene

SOURCE GeneReport for Unigene cluster for CAMTA2 Gene Hs.632242

mRNA Expression by UniProt/SwissProt for CAMTA2 Gene

Tissue specificity: Detected in brain. Expressed at constant levels throughout the cell cycle in neuroblastoma cell lines.
genes like me logo Genes that share expressions with CAMTA2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for CAMTA2 Gene

Orthologs for CAMTA2 Gene

This gene was present in the common ancestor of animals.

Orthologs for CAMTA2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CAMTA2 35
  • 99.03 (n)
  • 99 (a)
  • 99 (a)
(Bos Taurus)
Mammalia CAMTA2 35
  • 91.77 (n)
  • 95.73 (a)
  • 92 (a)
(Canis familiaris)
Mammalia CAMTA2 35
  • 89.49 (n)
  • 92.31 (a)
  • 88 (a)
(Mus musculus)
Mammalia Camta2 35
  • 88.73 (n)
  • 92.51 (a)
Camta2 16
Camta2 36
  • 89 (a)
(Monodelphis domestica)
Mammalia CAMTA2 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 80 (a)
(Rattus norvegicus)
Mammalia Camta2 35
  • 88.87 (n)
  • 92.67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.1392 35
(Danio rerio)
Actinopterygii CAMTA2 36
  • 39 (a)
zgc56118 35
fruit fly
(Drosophila melanogaster)
Insecta Camta 36
  • 14 (a)
(Caenorhabditis elegans)
Secernentea camt-1 36
  • 13 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 30 (a)
Species with no ortholog for CAMTA2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CAMTA2 Gene

Gene Tree for CAMTA2 (if available)
Gene Tree for CAMTA2 (if available)

Paralogs for CAMTA2 Gene

Paralogs for CAMTA2 Gene

Selected SIMAP similar genes for CAMTA2 Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with CAMTA2: view

Variants for CAMTA2 Gene

Sequence variations from dbSNP and Humsavar for CAMTA2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs171133 -- 4,975,630(+) CACTC(A/G)GGCTT intron-variant
rs238228 -- 4,975,665(+) GAGGC(A/G)AAACT intron-variant
rs238229 -- 4,973,825(+) TTGAG(A/G)TGGCC intron-variant
rs238230 -- 4,972,271(+) TCCTC(C/T)GGAGC reference, synonymous-codon
rs238231 -- 4,983,477(-) tgaaa(C/T)cctgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CAMTA2 Gene

Variant ID Type Subtype PubMed ID
nsv833349 CNV Loss 17160897
nsv907619 CNV Loss 21882294
nsv907620 CNV Loss 21882294
nsv833350 CNV Loss 17160897

Relevant External Links for CAMTA2 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CAMTA2 Gene

Disorders for CAMTA2 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for CAMTA2 Gene including...

Search for CAMTA2 Gene in MalaCards »
genes like me logo Genes that share disorders with CAMTA2: view

No data available for UniProtKB/Swiss-Prot for CAMTA2 Gene

Publications for CAMTA2 Gene

  1. A novel family of calmodulin-binding transcription activators in multicellular organisms. (PMID: 11925432) Bouche N. … Fromm H. (J. Biol. Chem. 2002) 2 3 4
  2. CAMTA in cardiac hypertrophy. (PMID: 16678087) Schwartz R.J. … Schneider M.D. (Cell 2006) 3 23
  3. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10048485) Nagase T. … Ohara O. (DNA Res. 1998) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for CAMTA2 Gene

Sources for CAMTA2 Gene

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