Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CAMSAP3 Gene

protein-coding   GIFtS: 44
GCID: GC19P007661

Calmodulin Regulated Spectrin-Associated Protein Family,...

(Previous name: KIAA1543)
(Previous symbol: KIAA1543)
  Search for CAMSAP3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Calmodulin Regulated Spectrin-Associated Protein Family, Member 31 2
KIAA15431 2 3 5
NEZHA2 5
Calmodulin-Regulated Spectrin-Associated Protein 32
Protein Nezha3

External Ids:    HGNC: 293071   Entrez Gene: 576622   Ensembl: ENSG000000768267   OMIM: 6126855   UniProtKB: Q9P1Y53   

Export aliases for CAMSAP3 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CAMSAP3 Gene:
CAMSAP3 (calmodulin regulated spectrin-associated protein family, member 3) is a protein-coding gene. GO annotations related to this gene include microtubule minus-end binding. An important paralog of this gene is CAMSAP1.

UniProtKB/Swiss-Prot: CAMP3_HUMAN, Q9P1Y5
Function: Microtubule minus-end binding protein that acts as a regulator of non-centrosomal microtubule dynamics
and organization. Specifically required for the biogenesis and the maintenance of zonula adherens by anchoring
the minus-end of microtubules to zonula adherens and by recruiting the kinesin KIFC3 to those junctional sites.
May regulate the nucleation and the polymerization of microtubules. Indirectly, through the microtubule
cytoskeleton, may regulate the organization of cellular organelles including the Golgi and the early endosomes




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CAMSAP3
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CAMSAP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAMSAP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.2   Ensembl cytogenetic band:  19p13.2   HGNC cytogenetic band: 19p13.3-p13.2

CAMSAP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAMSAP3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P007661:  view genomic region     (about GC identifiers)

Start:
7,660,788 bp from pter      End:
7,683,196 bp from pter
Size:
22,409 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CAMP3_HUMAN, Q9P1Y5 (See protein sequence)
Recommended Name: Calmodulin-regulated spectrin-associated protein 3  
Size: 1249 amino acids; 134750 Da
Subunit: Interacts with PLEKHA7. Interacts with CAMSAP2 (By similarity)
Miscellaneous: 'Nezha' is a deity in Chinese mythology
Secondary accessions: Q8NDF1
Alternative splicing: 2 isoforms:  Q9P1Y5-1   Q9P1Y5-2   

Explore the universe of human proteins at neXtProt for CAMSAP3: NX_Q9P1Y5

Explore proteomics data for CAMSAP3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CAMSAP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001073898.1  NP_065953.1  

    ENSEMBL proteins: 
     ENSP00000160298   ENSP00000416797  

    CAMSAP3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CAMSAP3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CAMSAP3
    GenScript Custom Purified and Recombinant Proteins Services for CAMSAP3
    Novus Biologicals CAMSAP3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CAMSAP3

     
    Search eBioscience for Proteins for CAMSAP3 

    CAMSAP3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CAMSAP3
    Novus Biologicals CAMSAP3 Antibody
    Abcam antibodies for CAMSAP3
    Cloud-Clone Corp. Antibodies for CAMSAP3
    Search ThermoFisher Antibodies for CAMSAP3
    LSBio Antibodies in human, mouse, rat for CAMSAP3

    CAMSAP3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CAMSAP3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CAMSAP3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CAMSAP3
    Cloud-Clone Corp. CLIAs for CAMSAP3
    Search eBioscience for ELISAs for CAMSAP3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    3 InterPro protein domains:
     IPR011033 PRC_barrel-like
     IPR001715 CH-domain
     IPR014797 CKK_domain

    Graphical View of Domain Structure for InterPro Entry Q9P1Y5

    ProtoNet protein and cluster: Q9P1Y5

    UniProtKB/Swiss-Prot: CAMP3_HUMAN, Q9P1Y5
    Domain: The CKK domain binds microtubules (By similarity)
    Similarity: Belongs to the CAMSAP1 family
    Similarity: Contains 1 CH (calponin-homology) domain
    Similarity: Contains 1 CKK domain


    Find genes that share domains with CAMSAP3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAMP3_HUMAN, Q9P1Y5
    Function: Microtubule minus-end binding protein that acts as a regulator of non-centrosomal microtubule dynamics
    and organization. Specifically required for the biogenesis and the maintenance of zonula adherens by anchoring
    the minus-end of microtubules to zonula adherens and by recruiting the kinesin KIFC3 to those junctional sites.
    May regulate the nucleation and the polymerization of microtubules. Indirectly, through the microtubule
    cytoskeleton, may regulate the organization of cellular organelles including the Golgi and the early endosomes

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008017microtubule binding ----
    GO:0051011microtubule minus-end binding IDA19041755
         
    Find genes that share ontologies with CAMSAP3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CAMSAP3:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CAMSAP3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CAMSAP3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CAMSAP3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CAMSAP3

    miRNA
    Products:
        
    miRTarBase miRNAs that target CAMSAP3:
    hsa-mir-10b-5p (MIRT047421), hsa-mir-16-5p (MIRT051280), hsa-mir-186-5p (MIRT044980), hsa-mir-99b-5p (MIRT044191), hsa-mir-615-3p (MIRT040427)

    Block miRNA regulation of human, mouse, rat CAMSAP3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CAMSAP3
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CAMSAP3
    Predesigned siRNA for gene silencing in human, mouse, rat CAMSAP3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CAMSAP3

    Clone
    Products:
         
    OriGene clones in human, mouse for CAMSAP3 (see all 10)
    OriGene ORF clones in mouse, rat for CAMSAP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CAMSAP3
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMSAP3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CAMSAP3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CAMSAP3
    Browse ESI BIO Cell Lines and PureStem Progenitors for CAMSAP3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMSAP3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CAMP3_HUMAN, Q9P1Y5: Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton. Note=Scattered in the
    cytoplasm, associated with the minus-end of microtubules and also detected at the centrosomes. Localizes along
    zonula adherens only at mature cell-cell contacts

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA19041755
    GO:0005813colocalizes with centrosome IDA--
    GO:0005874microtubule IEA--
    GO:0005915zonula adherens IDA19041755

    Find genes that share ontologies with CAMSAP3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for CAMSAP3 About    
    See pathways by source

    SuperPathContained pathways About
    1Stabilization and expansion of the E-cadherin adherens junction
    Stabilization and expansion of the E-cadherin adherens junction


    1 BioSystems Pathway for CAMSAP3
        Stabilization and expansion of the E-cadherin adherens junction


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CAMSAP3
    Interactions:

        Search GeneGlobe Interaction Network for CAMSAP3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    Selected Interacting proteins for CAMSAP3 (Q9P1Y52, 3 ENSP000004167974) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GSK3BP498412, 3MINT-8257383 I2D: score=2 
    ENSG00000258947Q135093I2D: score=1 
    PLEKHA7Q6IQ233, ENSP000003478834I2D: score=1 STRING: ENSP00000347883
    TUBB3Q135093I2D: score=1 
    TUBB4AP043503, ENSP000002640714I2D: score=1 STRING: ENSP00000264071
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IMP--
    GO:0010923negative regulation of phosphatase activity IDA19389623
    GO:0033043regulation of organelle organization IMP--
    GO:0034453microtubule anchoring IMP19041755
    GO:0045218zonula adherens maintenance IMP19041755

    Find genes that share ontologies with CAMSAP3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CAMSAP3 (CAMP3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CAMSAP3 gene (2 alternative transcripts): 
    NM_001080429.2  NM_020902.1  

    Unigene Cluster for CAMSAP3:

    Calmodulin regulated spectrin-associated protein family, member 3
    Hs.17686  [show with all ESTs]
    Unigene Representative Sequence: NM_001080429
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000160298(uc002mgv.4 uc002mgw.3) ENST00000446248(uc002mgu.4)
    ENST00000595692 ENST00000593434
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CAMSAP3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CAMSAP3
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CAMSAP3
    Predesigned siRNA for gene silencing in human, mouse, rat CAMSAP3
    Clone
    Products:
         
    OriGene clones in human, mouse for CAMSAP3 (see all 10)
    OriGene ORF clones in mouse, rat for CAMSAP3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CAMSAP3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMSAP3
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CAMSAP3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMSAP3
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CAMSAP3
      QuantiTect SYBR Green Assays in human, mouse, rat CAMSAP3
      QuantiFast Probe-based Assays in human, mouse, rat CAMSAP3

    Additional mRNA sequence: 

    AB040976.1 AF289580.1 AL833927.1 BC020431.1 BC035808.1 BC036935.1 BC064490.1 BC128201.1 
    BC128202.1 

    6 DOTS entries:

    DT.101981726  DT.446004  DT.75190293  DT.121467090  DT.92420568  DT.100751941 

    Selected AceView cDNA sequences (see all 128):

    BM824663 AI149820 BI761904 BF062442 BF591242 AI393938 AW611992 AA446272 
    BC020431 AW665069 CD672448 BM709036 BM702449 AI500651 AI972630 BE222659 
    BC036935 AL833927 AI014629 BM709565 AI222838 AB040976 AW952299 BF940312 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CAMSAP3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CAMSAP3 Expression
    About this image

    CAMSAP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CAMSAP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.17686
        Custom PCR Arrays for CAMSAP3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMSAP3
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CAMSAP3
    QuantiTect SYBR Green Assays in human, mouse, rat CAMSAP3
    QuantiFast Probe-based Assays in human, mouse, rat CAMSAP3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMSAP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for CAMSAP3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Camsap31 , 5 calmodulin regulated spectrin-associated protein family, more1, 5 82.82(n)1
    89.87(a)1
      8 (1.92 cM)5
    696971  NM_001163749.11  NP_001157221.11 
     35874505 
    lizard
    (Anolis carolinensis)
    Reptilia CAMSAP36
    calmodulin regulated spectrin-associated protein f...
    56(a)
    1 ↔ 1
    2(103087494-103140662)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG363856.12   -- 71.65(n)    BG363856.1 
    zebrafish
    (Danio rerio)
    Actinopterygii camsap31 calmodulin regulated spectrin-associated protein family, more 55.59(n)
    53.77(a)
      556256  XM_005163767.1  XP_005163824.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Patronin6
    Patronin
    14(a)
    1 → many
    2R(13406529-13423371)
    worm
    (Caenorhabditis elegans)
    Secernentea ptrn-16
    Protein PTRN-1, isoform b (ptrn-1) mRNA, complete ...
    17(a)
    1 → many
    X(17021812-17030219) WBGene00004121


    ENSEMBL Gene Tree for CAMSAP3 (if available)
    TreeFam Gene Tree for CAMSAP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CAMSAP3 gene
    CAMSAP12  CAMSAP22  

    Find genes that share paralogs with CAMSAP3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CAMSAP3 (see all 1265)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs72572971,2
    C,F--7304562(+) gcaggA/Gcaccg 2 -- int15Minor allele frequency- G:0.24NA CSA WA 243
    rs1170323481,2
    C,F--7304640(+) TGACGC/TACACA 2 -- int11Minor allele frequency- T:0.03EA 120
    rs1856358061,2
    --7304642(+) ACGCAC/GACACC 2 -- int10--------
    rs1415430441,2
    --7304690(+) GCGGTC/GCTGCT 2 -- int10--------
    rs1904908991,2
    --7304719(+) GCTCCG/TGGGTG 2 -- int10--------
    rs1929668461,2
    --7304731(+) AGCTTC/TGCTGA 2 -- int10--------
    rs72546881,2
    C,F,H--7304803(+) TTGTCG/CTTTAG 2 -- int19Minor allele frequency- C:0.12NS EA NA WA CSA 505
    rs1842514651,2
    --7304904(+) TCATGC/TCTGTA 2 -- int10--------
    rs72464101,2
    C,F--7305038(+) ggtggG/Tcgcct 2 -- int15Minor allele frequency- T:0.22NA CSA 9
    rs581239711,2
    C,F--7305082(+) GAATCG/ACTTGA 2 -- int14Minor allele frequency- A:0.25NA WA 8

    HapMap Linkage Disequilibrium report for CAMSAP3 (7660788 - 7683196 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for CAMSAP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2673205CNV Deletion23128226
    esv993190CNV Deletion20482838
    esv2656803CNV Deletion23128226
    nsv910970CNV Loss21882294
    nsv910979CNV Loss21882294
    nsv833730CNV Loss17160897
    nsv833731CNV Loss17160897
    dgv3712n71CNV Loss21882294
    esv2751809CNV Gain17911159

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CAMSAP3
    DNA2.0 Custom Variant and Variant Library Synthesis for CAMSAP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 612685    OMIM disorders: --


    Find genes that share disorders with CAMSAP3           About GenesLikeMe


    Export disorders for CAMSAP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CAMSAP3 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with CAMSAP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts. (PubMed id 19041755)1, 2, 3 Meng W.... Takeichi M. (Cell 2008)
    2. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    3. The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins. (PubMed id 19508979)1, 3 Baines A.J.... Phillips G.W. (Mol. Biol. Evol. 2009)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2. (PubMed id 11318610)1, 3 Acierno J.S. Jr....Slaugenhaupt S.A. (Genomics 2001)
    7. The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. (PubMed id 23084401)1 Singh G....Moore M.J. (Cell 2012)
    8. Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules. (PubMed id 23169647)2 Tanaka N.... Takeichi M. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 57662 HGNC: 29307 AceView: KIAA1543 Ensembl:ENSG00000076826 euGenes: HUgn57662
    ECgene: CAMSAP3 H-InvDB: CAMSAP3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA1543

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CAMSAP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CAMSAP3 gene:
    Search GeneIP for patents involving CAMSAP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CAMSAP3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for CAMSAP3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CAMSAP3  
     OriGene qSTAR qPCR primer pairs in human, mouse for CAMSAP3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for CAMSAP3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CAMSAP3   OriGene Custom Protein Services for CAMSAP3  

     
     
     Block miRNA regulation of human, mouse, rat CAMSAP3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CAMSAP3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAMSAP3 Predesigned siRNA for gene silencing in human, mouse, rat CAMSAP3
     QuantiFast Probe-based Assays in human, mouse, rat CAMSAP3 QuantiTect SYBR Green Assays in human, mouse, rat CAMSAP3
     Custom PCR Arrays for CAMSAP3 Search Chromatin IP Primers for CAMSAP3
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CAMSAP3 Search GeneGlobe Interaction Network for CAMSAP3
     Search Regulatory tfbs for CAMSAP3
     GenScript Custom Purified and Recombinant Proteins Services for CAMSAP3 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for CAMSAP3
     GenScript Custom Assay Services for CAMSAP3 GenScript Custom overexpressing Cell Line Services for CAMSAP3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CAMSAP3 (CAMP3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CAMSAP3 antibodies
     CAMSAP3 lysates
     Antibodies for CAMSAP3
     See all of Abcam's Antibodies, Kits and Proteins for CAMSAP3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CAMSAP3
     Antibodies for CAMSAP3
     ELISAs for CAMSAP3
     CLIAs for CAMSAP3



     Browse ESI BIO Cell Lines and PureStem Progenitors for CAMSAP3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMSAP3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for CAMSAP3
     Browse SwitchGear Promoter luciferase reporter plasmids for CAMSAP3
     Search ThermoFisher Antibodies for CAMSAP3
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CAMSAP3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CAMSAP3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CAMSAP3
     LSBio Antibodies in human, mouse, rat for CAMSAP3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for CAMSAP3
      Search eBioscience for proteins for CAMSAP3
      Search eBioscience for elisas for CAMSAP3
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CAMSAP3 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4