Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CAMP Gene

protein-coding   GIFtS: 59
GCID: GC03P048264

Cathelicidin Antimicrobial Peptide

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cathelicidin Antimicrobial Peptide1 2     CRAMP2
FALL392 3 5     FALL-392
18 KDa Cationic Antimicrobial Protein2 3     LL372
CAP-182 3     hCAP-183
CAP182 3     

External Ids:    HGNC: 14721   Entrez Gene: 8202   Ensembl: ENSG000001640477   OMIM: 6004745   UniProtKB: P499133   

Export aliases for CAMP gene to outside databases

Previous GC identifers: GC03P048066 GC03P047547 GC03P048225 GC03P048240


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CAMP Gene:
This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal
signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is
produced by extracellular proteolysis from the C-terminus. The encoded protein has several functions in addition
to antimicrobial activity, including cell chemotaxis, immune mediator induction and inflammatory response
regulation. (provided by RefSeq, Aug 2011)

GeneCards Summary for CAMP Gene: 
CAMP (cathelicidin antimicrobial peptide) is a protein-coding gene. Diseases associated with CAMP include rosacea, and eczema herpeticum, and among its related super-pathways are Insulin receptor recycling and Regulation of Cholesterol Biosynthesis by SREBP (SREBF). GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: CAMP_HUMAN, P49913
Function: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity

Gene Wiki entry for CAMP (Cathelicidin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CAMP gene promoter:
         E2F-3a   CREB   E2F   deltaCREB   STAT3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCAMP promoter sequence
   Search SABiosciences Chromatin IP Primers for CAMP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAMP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.3   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.3

CAMP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAMP gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P048264:  view genomic region     (about GC identifiers)

Start:
48,264,837 bp from pter      End:
48,266,981 bp from pter
Size:
2,145 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CAMP_HUMAN, P49913 (See protein sequence)
Recommended Name: Cathelicidin antimicrobial peptide precursor  
Size: 170 amino acids; 19301 Da
Subcellular location: Secreted
Caution: PubMed:11238224 sequence was incorrectly assigned to originate from M.mulatta
6 PDB 3D structures from and Proteopedia for CAMP:
2FBS (3D)        2FBU (3D)        2FCG (3D)        2K6O (3D)        2LMF (3D)        4EYC (3D)    
Secondary accessions: Q71SN9

Explore the universe of human proteins at neXtProt for CAMP: NX_P49913

Explore proteomics data for CAMP at MOPED 

Post-translational modifications:

  • UniProtKB: The N-terminus is blocked
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P49913

  • CAMP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CAMP Protein Expression
    REFSEQ proteins: NP_004336.3  
    ENSEMBL proteins: 
     ENSP00000296435   ENSP00000458149  
    Reactome Protein details: P49913
    Human Recombinant Protein Products for CAMP: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CAMP
    OriGene Protein Over-expression Lysate for CAMP
    OriGene MassSpec for CAMP 
    OriGene Custom Protein Services for CAMP
    GenScript Custom Purified and Recombinant Proteins Services for CAMP
    Novus Biologicals CAMP Proteins
    Novus Biologicals CAMP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CAMP 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005618cell wall TAS--
    GO:0005829cytosol TAS--
    GO:0042581specific granule ----

    CAMP for ontologies           About GeneDecksing



    CAMP Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CAMP (CAMP/LL37/FALL39)
    OriGene Antibodies for CAMP
    OriGene Custom Antibody Services for CAMP
    GenScript Superior Antibodies for CAMP
    Novus Biologicals CAMP Antibodies
    Abcam antibodies for CAMP
    Cloud-Clone Corp. Antibodies for CAMP 
    ThermoFisher Antibodies for CAMP
    LSBio Antibodies in human, mouse, rat for CAMP 

    Assay Products for CAMP: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CAMP
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CAMP
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CAMP 
    Cloud-Clone Corp. CLIAs for CAMP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR022746 Cathlecidin_C
     IPR001894 Cathelicidin
     IPR018216 Cathelicidin_CS

    Graphical View of Domain Structure for InterPro Entry P49913

    ProtoNet protein and cluster: P49913

    1 Blocks protein domain: IPB001894 Cathelicidin

    UniProtKB/Swiss-Prot: CAMP_HUMAN, P49913
    Similarity: Belongs to the cathelicidin family


    CAMP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAMP_HUMAN, P49913
    Function: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity

         Genatlas biochemistry entry for CAMP:
    cathelicidin cationic antimicrobial peptide,cathelin family,expressed in the specific granules of neutrophils,also
    expressed in bone marrow and testis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    CAMP for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for CAMP:
     Decreased NANOG protein expres  Decreased OCT4 protein express  Decreased POU5F1-GFP protein e 

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Camp):
     immune system  mortality/aging 

    CAMP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Camptm1Rlg for CAMP

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CAMP 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CAMP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CAMP 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CAMP 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CAMP
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CAMP
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CAMP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAMP

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CAMP
    Sirion Biotech Customized adenovirus for overexpression of CAMP

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CAMP (see all 7)
    OriGene ORF clones in mouse, rat for CAMP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CAMP (NM_004345)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAMP
    Sirion Biotech Customized lentivirus for stable overexpression of CAMP 
                         Customized lentivirus expression plasmids for stable overexpression of CAMP 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CAMP
    Search LifeMap BioReagents cell lines for CAMP
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CAMP About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Insulin receptor recycling
    Latent infection of Homo sapiens with Mycobacterium tuberculosis0.64
    Phagosomal maturation (early endosomal stage)0.64
    2Regulation of Cholesterol Biosynthesis by SREBP (SREBF)
    SREBP signalling0.37
    3Gastric acid secretion
    Salivary secretion0.34
    4Tuberculosis
    Tuberculosis
    5Disease
    Disease

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for CAMP
        SREBP signalling
    Integrated Pancreatic Cancer Pathway

    3        Reactome Pathways for CAMP
        Phagosomal maturation (early endosomal stage)
    Latent infection of Homo sapiens with Mycobacterium tuberculosis
    Disease


    2         Kegg Pathways  (Kegg details for CAMP):
        Salivary secretion
    Tuberculosis


    CAMP for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CAMP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/14 Interacting proteins for CAMP (P499131, 3 ENSP000002964354) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IGF1RP080691, 3, ENSP000002680354EBI-6378485,EBI-475981 I2D: score=2 STRING: ENSP00000268035
    CTSGP083113, ENSP000002163364I2D: score=1 STRING: ENSP00000216336
    ELANEP082463, ENSP000002636214I2D: score=1 STRING: ENSP00000263621
    PRTN3P241583, ENSP000002343474I2D: score=1 STRING: ENSP00000234347
    GAPDHP044063I2D: score=1 
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006952defense response ----
    GO:0042742defense response to bacterium IEA--
    GO:0044130negative regulation of growth of symbiont in host ----
    GO:0044140negative regulation of growth of symbiont on or near host surface IDA16177355
    GO:0050829defense response to Gram-negative bacterium ----

    CAMP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CAMP for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CAMP

    1 DrugBank Compound for CAMP    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Selenocysteine-- 4408-78-0target--17139284 17016423 10592235

    10/67 Novoseek inferred chemical compound relationships for CAMP gene (see all 67)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hbd2 85.9 12 12819054 (4), 17943185 (2), 16926414 (1), 15886266 (1) (see all 6)
    pr 39 78.1 1 17343577 (1)
    forskolin 64.3 45 15381832 (2), 14701824 (2), 8908208 (2), 15985706 (2) (see all 30)
    ibmx 52.2 19 15689414 (1), 7508195 (1), 8078306 (1), 18983503 (1) (see all 10)
    vitamin d 49.8 30 19389235 (4), 19005165 (2), 19133797 (2), 15985530 (2) (see all 9)
    pge2 49.5 40 9024261 (3), 15833737 (2), 18923446 (2), 15626689 (2) (see all 21)
    1,25 dihydroxy vitamin d3 45.8 5 15985530 (2), 19948723 (1)
    25-hydroxyvitamin d 44.1 2 19389235 (1), 16957024 (1)
    lipoteichoic acid 40.8 2 12244186 (1), 16940084 (1)
    iloprost 39.5 9 8908208 (3), 14670842 (1), 7547677 (1), 18983503 (1)

    Search CenterWatch for drugs/clinical trials and news about CAMP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CAMP gene: 
    NM_004345.4  

    Unigene Cluster for CAMP:

    Cathelicidin antimicrobial peptide
    Hs.51120  [show with all ESTs]
    Unigene Representative Sequence: BU506539
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000296435(uc003csj.2) ENST00000576243
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CAMP
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CAMP
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CAMP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAMP
    Clone
    Products:
         
    OriGene clones in human, mouse for CAMP (see all 7)
    OriGene ORF clones in mouse, rat for CAMP
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CAMP (NM_004345)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAMP
    Sirion Biotech Customized lentivirus for stable overexpression of CAMP 
                         Customized lentivirus expression plasmids for stable overexpression of CAMP 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CAMP
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMP
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAMP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAMP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAMP

    Additional mRNA sequence: 

    AY162210.1 AY251531.1 BC055089.1 CR457083.1 CR541961.1 U19970.1 X89658.1 Z38026.1 

    1 DOTS entry:

    DT.210451 

    24/45 AceView cDNA sequences (see all 45):

    NM_004345 BM712116 BM670409 AW574631 BX280365 CR541961 BF893660 CR457083 
    AA770349 U19970 BF893640 BC055089 AY162210 AY251531 BF893650 X89658 
    AJ706901 AJ706514 AJ706132 AJ706351 BP370445 AW404163 BF902396 BU599019 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CAMP expression in normal human tissues (normalized intensities)      CAMP embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGACCCAAA
    CAMP Expression
    About this image


    CAMP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 8 entries
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
             Bone Marrow CD105+ Cells   
             neutrophils   
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Bone Marrow
             bone marrow   
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Granulosa Cells Primary Follicle
     
     Spleen (Hematopoietic System)
             spleen ; cells in red pulp   

    See CAMP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CAMP

    SOURCE GeneReport for Unigene cluster: Hs.51120

    UniProtKB/Swiss-Prot: CAMP_HUMAN, P49913
    Tissue specificity: Expressed in bone marrow and testis and neutrophils

        SABiosciences Expression via Pathway-Focused PCR Arrays including CAMP: 
              Innate & Adaptive Immune Responses in human mouse rat
              Antibacterial Response in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CAMP
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMP
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CAMP
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAMP
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAMP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CAMP gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Camp1 , 5 cathelicidin antimicrobial peptide1, 5 71.95(n)1
    56.71(a)1
      9 (59.80 cM)5
    127961  NM_009921.21  NP_034051.21 
     1098473755 
    lizard
    (Anolis carolinensis)
    Reptilia CAMP6
    cathelicidin antimicrobial peptide
    28(a)
    1 ↔ 1
    GL343332.1(1009461-1011648)


    ENSEMBL Gene Tree for CAMP (if available)
    TreeFam Gene Tree for CAMP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/109 SNPs in CAMP are shown (see all 109)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1403039321,2
    --48263002(+) TTTATC/TTCTCC 1 -- us2k10--------
    rs1868337361,2
    --48263096(+) GAGGTA/CGAATC 1 -- us2k10--------
    rs1453425111,2
    --48263229(+) AAAGAG/TCAGGA 1 -- us2k10--------
    rs1130068661,2
    C--48263273(+) TGACAT/GTCTGG 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1915941451,2
    --48263474(+) AGGTGA/GAGTCT 1 -- us2k10--------
    rs1837606431,2
    C--48263517(+) ATGGCA/GGCAGG 1 -- us2k10--------
    rs767211261,2
    C,F--48263656(+) GGGACG/ATTCAT 1 -- us2k12Minor allele frequency- A:0.17CSA WA 120
    rs779938281,2
    C,F--48263782(+) GTGACC/TCCACA 1 -- us2k11Minor allele frequency- T:0.03NA 120
    rs1888797051,2
    --48263933(+) ACCAGA/GCTTGA 1 -- us2k10--------
    rs1932365631,2
    --48264021(+) AGAAGC/GGTAGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CAMP (48264837 - 48266981 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CAMP:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv834682CNV Gain17160897


    Human Gene Mutation Database (HGMD): CAMP
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CAMP
    DNA2.0 Custom Variant and Variant Library Synthesis for CAMP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 600474    OMIM disorders: --

    20/55 diseases for CAMP (see all 55):    About MalaCards
    rosacea    eczema herpeticum    catecholaminergic polymorphic ventricular tachycardia    eczema
    cardiovascular disease risk factor )    periodontal disease    cellulitis    severe congenital neutropenia
    disseminated intravascular coagulation    polycystic kidney disease    cholera    kidney disease
    neutropenia    shigellosis    acne    cystic fibrosis
    vaccinia    skin disease    acute promyelocytic leukemia    periodontitis


    CAMP for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

    10/38 Novoseek inferred disease relationships for CAMP gene (see all 38)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    eczema vaccinatum 63.9 1 14734759 (1)
    skin infection 59.7 3 15728389 (1), 15587410 (1)
    psoriasis 54 30 12374875 (3), 16100459 (3), 19645825 (3), 15587410 (3) (see all 11)
    dermatitis atopic 52.7 12 12374875 (2), 16100459 (2), 19808939 (1), 18573153 (1) (see all 8)
    skin diseases 49.4 7 16034119 (2), 20190140 (1), 16100459 (1), 10225921 (1)
    bacterial infections 49.3 9 19605696 (1), 12454100 (1), 12819054 (1), 16751768 (1) (see all 9)
    cholera 45.7 12 17697117 (3), 15345481 (1), 15689414 (1), 11956020 (1) (see all 10)
    inflammation 44.2 30 16740661 (2), 19075071 (2), 16340000 (1), 19309368 (1) (see all 22)
    cystic fibrosis 44 5 7529238 (1), 11053013 (1), 15463886 (1), 9736536 (1) (see all 5)
    arpkd 32.6 1 16767405 (1)

    Human Genome Epidemiology (HuGE) Navigator: CAMP (166 documents)

    Export disorders for CAMP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CAMP gene, integrated from 9 sources (see all 463):
    (articles sorted by number of sources associating them with CAMP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human CAP18: a novel antimicrobial lipopolysaccharide-binding protein. (PubMed id 7890387)1, 2, 9 Larrick J.W.... Wright S.C. (1995)
    2. Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles. (PubMed id 18818205)1, 2 Wang G. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Rhesus monkey (Macaca mulatta) mucosal antimicrobial peptides are close homologues of human molecules. (PubMed id 11238224)1, 2 Bals R.... Wilson J.M. (2001)
    5. The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. (PubMed id 8681941)1, 2 Gudmundsson G.H....Salcedo R. (1996)
    6. Structural, functional analysis and localization of the human CAP18 gene. (PubMed id 8946956)1, 2 Larrick J.W....Balint R.F. (1996)
    7. hCAP-18, a cathelin/pro-bactenecin-like protein of human neutrophil specific granules. (PubMed id 7615076)1, 2 Cowland J.B.... Borregaard N. (1995)
    8. Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. (PubMed id 7624374)1, 3 Gudmundsson G.H....Boman H.G. (1995)
    9. FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. (PubMed id 7529412)1, 2 Agerberth B....Gudmundsson G.H. (1995)
    10. LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypert onic saline. (PubMed id 19542465)1, 9 Bergsson G....McElvaney N.G. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 820 HGNC: 1472 AceView: CAMP Ensembl:ENSG00000164047 euGenes: HUgn820
    ECgene: CAMP Kegg: 820 H-InvDB: CAMP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CAMP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CAMP gene:
    Search GeneIP for patents involving CAMP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for CAMP (CAMP/LL37/FALL39)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CAMP   OriGene RNAi products in human, mouse, rat for CAMP  
     OriGene qPCR primer pairs and template standards for CAMP   OriGene Protein Over-expression Lysate for CAMP  
     OriGene MassSpec something-or-other for CAMP   OriGene clones in human, mouse for CAMP  
     OriGene qSTAR qPCR primer pairs in human, mouse for CAMP   OriGene Purified Protein for CAMP  
     OriGene ORF clones in mouse, rat for CAMP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CAMP   OriGene Custom Protein Services for CAMP  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CAMP
     QIAGEN SeqTarget long-range PCR primers for resequencing CAMP
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAMP
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CAMP
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CAMP
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CAMP
     GenScript Custom Purified and Recombinant Proteins Services for CAMP GenScript cDNA clones with any tag delivered in your preferred vector for CAMP
     GenScript Custom Assay Services for CAMP GenScript Superior Antibodies for CAMP
     GenScript Custom overexpressing Cell Line Services for CAMP CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CAMP promoter
     Search Chromatin IP Primers for CAMP
     RT2 qPCR Primer Assay in human, mouse, rat CAMP
     GNC Network for CAMP
     SABiosciences PCR Arrays including human, mouse, rat CAMP
     Search Tocris compounds for CAMP
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CAMP antibodies
     CAMP proteins
     CAMP lysates
     Antibodies for CAMP
     See all of Abcam's Antibodies, Kits and Proteins for CAMP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for CAMP
     Antibodies for CAMP
     ELISAs for CAMP
     CLIAs for CAMP
     Search LifeMap BioReagents cell lines for CAMP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMP
     Browse SwitchGear 3'UTR luciferase reporter plasmids for CAMP
     SwitchGear Promoter luciferase reporter plasmids for CAMP
     ThermoFisher Antibodies for CAMP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAMP
     inGenious Targeting Laboratory - Custom generated mouse model solutions for CAMP
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CAMP
    Customized:
     lentivirus for stable overexpression of CAMP
     lentivirus expression plasmids for stable overexpression of CAMP
     adenovirus for overexpression of CAMP
     LSBio Antibodies in human, mouse, rat for CAMP
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CAMP gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4