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CAMKV Gene

protein-coding   GIFtS: 57
GCID: GC03M049895

CaM Kinase-Like Vesicle-Associated

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CaM Kinase-Like Vesicle-Associated1 2
1G52 5
VACAMKL2
CaM Kinase-Like Vesicle-Associated Protein2
Vesicle-Associated Calmodulin-Binding Protein2

External Ids:    HGNC: 287881   Entrez Gene: 790122   Ensembl: ENSG000001640767   OMIM: 6149935   UniProtKB: Q8NCB23   

Export aliases for CAMKV gene to outside databases

Previous GC identifer: GC03M049875


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CAMKV Gene:
CAMKV (CaM kinase-like vesicle-associated) is a protein-coding gene. Diseases associated with CAMKV include schizophrenia, and cerebritis. GO annotations related to this gene include calmodulin binding and protein kinase activity. An important paralog of this gene is PNCK.

UniProtKB/Swiss-Prot: CAMKV_HUMAN, Q8NCB2
Function: Does not appear to have detectable kinase activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CAMKV gene promoter:
         AP-1   NRSF form 1   NRSF form 2   GATA-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCAMKV promoter sequence
   Search Chromatin IP Primers for CAMKV

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CAMKV


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.31

CAMKV Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAMKV gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M049895:  view genomic region     (about GC identifiers)

Start:
49,895,421 bp from pter      End:
49,907,655 bp from pter
Size:
12,235 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CAMKV_HUMAN, Q8NCB2 (See protein sequence)
Recommended Name: CaM kinase-like vesicle-associated protein  
Size: 501 amino acids; 54354 Da
Cofactor: Calcium (By similarity)
Subunit: Interacts with calmodulin, in the presence of calcium (By similarity)
Secondary accessions: A6NFD4 Q6FIB8 Q8NBS8 Q8NC85 Q8NDU4 Q8WTT8 Q9BQC9 Q9H0Q5
Alternative splicing: 3 isoforms:  Q8NCB2-1   Q8NCB2-2   Q8NCB2-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CAMKV: NX_Q8NCB2

Explore proteomics data for CAMKV at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CAMKV Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_076951.2  
    ENSEMBL proteins: 
     ENSP00000296471   ENSP00000418809   ENSP00000417614   ENSP00000419195   ENSP00000420139  
     ENSP00000420053   ENSP00000420724   ENSP00000420766   ENSP00000420000  

    CAMKV Human Recombinant Protein Products:

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    OriGene MassSpec for CAMKV
    OriGene Custom Protein Services for CAMKV
    GenScript Custom Purified and Recombinant Proteins Services for CAMKV
    Novus Biologicals CAMKV Protein
    Novus Biologicals CAMKV Lysates
    Sino Biological Recombinant Protein for CAMKV
    Sino Biological Cell Lysate for CAMKV
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CAMKV

    CAMKV Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    LSBio Antibodies in human, mouse, rat for CAMKV

    CAMKV Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for CAMKV
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    Cloud-Clone Corp. ELISAs for CAMKV
    Cloud-Clone Corp. CLIAs for CAMKV


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    IUPHAR Guide to PHARMACOLOGY protein family classification: CaM kinase-like vesicle-associated
    CAMK-unique family

    4 InterPro protein domains:
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR000719 Prot_kinase_dom
     IPR020636 Ca/CaM-dep_Ca-dep_prot_Kinase

    Graphical View of Domain Structure for InterPro Entry Q8NCB2

    ProtoNet protein and cluster: Q8NCB2

    UniProtKB/Swiss-Prot: CAMKV_HUMAN, Q8NCB2
    Domain: The protein kinase domain is predicted to be catalytically inactive
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family
    Similarity: Contains 1 protein kinase domain


    CAMKV for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAMKV_HUMAN, Q8NCB2
    Function: Does not appear to have detectable kinase activity

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005516calmodulin binding IEA--
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    CAMKV for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for CAMKV:
     Decreased substrate adherent c  Increased cell death in DLD-1   Increased colony dispersion (i  Synthetic lethal with Ras 

         1 MGI phenotypic allele for Camkv (no phenotypes)

    CAMKV for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CAMKV
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CAMKV

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CAMKV
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CAMKV

    miRNA
    Products:
        
    miRTarBase miRNAs that target CAMKV:
    hsa-mir-26a-5p (MIRT050087), hsa-mir-195-5p (MIRT044859), hsa-mir-30b-5p (MIRT046108), hsa-mir-30d-3p (MIRT038684), hsa-mir-92a-3p (MIRT048955), hsa-mir-16-5p (MIRT051070), hsa-mir-30a-5p (MIRT049929), hsa-mir-30c-5p (MIRT047834), hsa-mir-23a-3p (MIRT050386)

    Block miRNA regulation of human, mouse, rat CAMKV using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CAMKV (see all 24):
    hsa-miR-185* hsa-miR-3660 hsa-miR-2909 hsa-miR-15a hsa-miR-4267 hsa-miR-103a hsa-miR-424 hsa-miR-3649
    SwitchGear 3'UTR luciferase reporter plasmidCAMKV 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CAMKV
    Predesigned siRNA for gene silencing in human, mouse, rat CAMKV

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for CAMKV

    Clone
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    OriGene clones in human, mouse for CAMKV (see all 7)
    OriGene ORF clones in mouse, rat for CAMKV
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CAMKV (NM_024046)
    Sino Biological Human cDNA Clone for CAMKV
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMKV
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAMKV

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CAMKV 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMKV


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CAMKV_HUMAN, Q8NCB2: Cell membrane; Peripheral membrane protein (By similarity). Cytoplasmic vesicle membrane;
    Peripheral membrane protein (By similarity). Note=Predominantly observed in association with the plasma membrane
    of soma and in neurites, both axons and dendrites. May be associated with vesicular structures (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    nucleus2
    cytoskeleton1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0030659cytoplasmic vesicle membrane IEA--

    CAMKV for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CAMKV About    
    See pathways by source

    SuperPathContained pathways About
    1EGFR Signaling Pathway
    EGFR Signaling Pathway


    1 Sino Biological Pathway for CAMKV
        EGFR Signaling Pathway


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CAMKV
    Interactions:

        Search GeneGlobe Interaction Network for CAMKV

    4 Interacting proteins for CAMKV (Q8NCB22, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TCEA2Q155603I2D: score=4 
    YWHABP319463I2D: score=1 
    --Q86VL03, 2MINT-64828 I2D: score=1 
    --Q86VL03, 2MINT-64828 I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    CAMKV for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CAMKV

    1 HMDB Compound for CAMKV    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CAMKV gene: 
    NM_024046.3  

    Unigene Cluster for CAMKV:

    CaM kinase-like vesicle-associated
    Hs.145156  [show with all ESTs]
    Unigene Representative Sequence: AL833943
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000475665(uc003cxw.1 uc003cxx.1) ENST00000296471 ENST00000488336
    ENST00000463537 ENST00000477224(uc003cxt.1 uc011bcy.1 uc003cxv.1 uc003cxu.2 uc011bcz.1 uc011bda.1 uc011bdb.1)
    ENST00000487726 ENST00000467248 ENST00000466940 ENST00000478149 ENST00000466535
    ENST00000483811 ENST00000480398 ENST00000472895 ENST00000479704 ENST00000498324
    ENST00000476105
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CAMKV using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CAMKV (see all 24):
    hsa-miR-185* hsa-miR-3660 hsa-miR-2909 hsa-miR-15a hsa-miR-4267 hsa-miR-103a hsa-miR-424 hsa-miR-3649
    SwitchGear 3'UTR luciferase reporter plasmidCAMKV 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CAMKV
    Predesigned siRNA for gene silencing in human, mouse, rat CAMKV
    Clone
    Products:
         
    OriGene clones in human, mouse for CAMKV (see all 7)
    OriGene ORF clones in mouse, rat for CAMKV
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CAMKV (NM_024046)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CAMKV
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CAMKV
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CAMKV
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMKV
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CAMKV
      QuantiTect SYBR Green Assays in human, mouse, rat CAMKV
      QuantiFast Probe-based Assays in human, mouse, rat CAMKV

    Additional mRNA sequence: 

    AK074856.1 AK074899.1 AK075294.1 AK226073.1 AK295588.1 AK297258.1 AK297437.1 AK299953.1 
    AK315525.1 AL136697.1 AL833943.1 AL834461.1 BC000497.2 BC001921.1 BC005828.2 BC017363.2 
    BC019256.1 BC033374.1 BX647074.1 CR533508.1 

    19 DOTS entries:

    DT.112558  DT.120859369  DT.100753832  DT.91765629  DT.100810646  DT.120859504  DT.120859460  DT.120859443 
    DT.100810641  DT.100810647  DT.70100518  DT.120859486  DT.97825126  DT.100810642  DT.120859330  DT.120859338 
    DT.120859458  DT.95274671  DT.100810640 

    Selected AceView cDNA sequences (see all 147):

    D51509 BC005828 CR615725 BM675995 BX094603 BX418742 AI341054 CR608102 
    AK075294 AA339026 AK074856 AL136697 BE797447 BC001921 AL833943 AW298755 
    AL534084 BC017363 CB152366 BE252841 NM_024046 AL834461 BC000497 BE254222 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CAMKV (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c · 2d ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^
    SP1:                                                        -                 -     -                                                                           
    SP2:                                                        -                 -     -                                                                           
    SP3:                                                        -                 -     -                             -     -                                       
    SP4:                                                        -                 -     -     -     -                                                               
    SP5:                                                  -     -     -     -     -     -     -                                                                     

    ExUns: 12a · 12b · 12c
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for CAMKV

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CAMKV expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGTGGGTC
    CAMKV Expression
    About this image


    CAMKV expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebellum
             Ventral/hypothalamic-like neurons
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 3 entries
             Human embryonic stem cells (family)
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Mesenchymal Condensate Cells Zeugopod
             Autopod Long Bone
     
     Neurons
             Glycinergic Amacrine Cells Inner Nuclear Layer
             Ventral/hypothalamic-like neurons
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
    CAMKV Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CAMKV Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.145156
        Custom PCR Arrays for CAMKV
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CAMKV
    OriGene qSTAR qPCR primer pairs in human, mouse for CAMKV
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CAMKV
    QuantiTect SYBR Green Assays in human, mouse, rat CAMKV
    QuantiFast Probe-based Assays in human, mouse, rat CAMKV
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMKV

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CAMKV gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Camkv1 , 5 CaM kinase-like vesicle-associated1, 5 88.82(n)1
    93.41(a)1
      9 (59.07 cM)5
    2356041  NM_145621.21  NP_663596.11 
     1079359205 
    chicken
    (Gallus gallus)
    Aves CAMKV1 CaM kinase-like vesicle-associated 80.05(n)
    87.05(a)
      770854  XM_001234174.3  XP_001234175.3 
    lizard
    (Anolis carolinensis)
    Reptilia CAMKV6
    CaM kinase-like vesicle-associated
    73(a)
    1 ↔ 1
    2(147612574-147675985)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.264662 Xenopus laevis transcribed sequence with moderate similarity more 76.76(n)    CD361415.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc635062 hypothetical protein MGC63506 77.19(n)   393422  BC055127.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CaMKII6
    Calcium/calmodulin-dependent protein kinase II
    25(a)
    1 → many
    4(1055914-1074329)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-436
    Protein UNC-43, isoform r (unc-43) mRNA, complete ...
    20(a)
    1 → many
    IV(10324317-10350217) WBGene00006779


    ENSEMBL Gene Tree for CAMKV (if available)
    TreeFam Gene Tree for CAMKV (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CAMKV gene
    PNCK2  CAMK1G2  PSKH22  DCX2  DCLK22  CAMK2A2  CAMK1D2  DCLK12  
    PSKH12  CAMK42  CAMK2D2  DCLK32  CAMK2G2  CAMK2B2  CAMK12  
    Selected SIMAP similar genes for CAMKV using alignment to 8 protein entries:     CAMKV_HUMAN (see all proteins) (see all similar genes):
    CAMK1    CAMK1D    MARK4    MARK3    PHKG2    DAPK1
    PSKH1    STK36    MGC45428    STK17A    PNCK    CAMK1G
    PHKG1    CAMK4    RPS6KA1    CAMK2A    HUNK    PSKH2

    CAMKV for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CAMKV (see all 245)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0413374
    A colorectal adenocarcinoma sample4--see VAR_0413372 R W mis40--------
    VAR_0413384
    An ovarian serous carcinoma sample4--see VAR_0413382 G S mis40--------
    VAR_0413394
    A colorectal adenocarcinoma sample4--see VAR_0413392 R W mis40--------
    rs1816308641,2
    --49896046(+) GCAGCC/TCACTG 1 -- ut310--------
    rs1858051531,2
    --49896060(+) GACTCA/GGAAAG 1 -- ut310--------
    rs1888022381,2
    --49896065(+) GGAAAA/GGCAGG 1 -- ut310--------
    rs1812637971,2
    --49896416(+) GGCAAA/GAAGGG 1 -- ut310--------
    rs67975001,2
    C,F,A,H--49896618(+) CTAGTT/AATGCC 1 -- ut3113Minor allele frequency- A:0.08NA NS EA WA 896
    rs1427819861,2
    --49896695(+) CCCCTC/TATCCA 1 -- ut310--------
    rs1112722051,2
    C--49896727(+) CCCTGC/-CCCCC 1 -- ut311Minor allele frequency- -:0.50CSA 2

    HapMap Linkage Disequilibrium report for CAMKV (49895421 - 49907655 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CAMKV:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv876766CNV Loss21882294
    nsv834688CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CAMKV
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614993    OMIM disorders: --

    3 diseases for CAMKV:    
    About MalaCards
    schizophrenia    cerebritis    neuronitis


    CAMKV for disorders           About GeneDecksing

    Genetic Association Database (GAD): CAMKV
    Human Genome Epidemiology (HuGE) Navigator: CAMKV (1 document)

    Export disorders for CAMKV gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CAMKV gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with CAMKV)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population. (PubMed id 19367581)1, 4 So H.C....Sham P.C. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    6. 1G5: a calmodulin-binding, vesicle-associated, protein kinase-like protein enriched in forebrain neurites. (PubMed id 8283228)1, 9 Godbout M....Sutcliffe J.G. (J. Neurosci. 1994)
    7. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79012 HGNC: 28788 AceView: MGC8407 Ensembl:ENSG00000164076 euGenes: HUgn79012
    ECgene: CAMKV H-InvDB: CAMKV

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CAMKV Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CAMKV gene:
    Search GeneIP for patents involving CAMKV

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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