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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CAMK1G Gene

protein-coding   GIFtS: 63
GCID: GC01P209757

Calcium/Calmodulin-Dependent Protein Kinase IG

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Calcium/Calmodulin-Dependent Protein Kinase IG1 2     CLICK III2 3
CaM Kinase I Gamma2 3     EC 2.7.11.173 8
CaM Kinase IG2 3     CLICKIII2
CaM-KI Gamma2 3     caMKIG2
CaMK-Like CREB Kinase III2 3     Calcium/Calmodulin-Dependent Protein Kinase Type 1G2
CaMKI Gamma2 3     dJ272L16.12
CLICK32 3     CaMKIG3
VWS12 3     EC 2.7.118

External Ids:    HGNC: 145851   Entrez Gene: 571722   Ensembl: ENSG000000081187   OMIM: 6149945   UniProtKB: Q96NX53   

Export aliases for CAMK1G gene to outside databases

Previous GC identifers: GC01P208396 GC01P205462 GC01P206396 GC01P206836 GC01P206145 GC01P207823 GC01P180432


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CAMK1G Gene:
This gene encodes a protein similar to calcium/calmodulin dependent protein kinase, however, its exact function is
not known. (provided by RefSeq, Jul 2008)

GeneCards Summary for CAMK1G Gene: 
CAMK1G (calcium/calmodulin-dependent protein kinase IG) is a protein-coding gene. Diseases associated with CAMK1G include van der woude syndrome, and neuronitis, and among its related super-pathways are cAMP Pathway and Signaling Involved in Cardiac Hypertrophy. GO annotations related to this gene include calmodulin binding and calmodulin-dependent protein kinase activity. An important paralog of this gene is PNCK.

UniProtKB/Swiss-Prot: KCC1G_HUMAN, Q96NX5
Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade.
In vitro phosphorylates transcription factor CREB1 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_167186.1  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CAMK1G gene promoter:
         Max1   ISGF-3   AML1a   Tal-1beta   MZF-1   CP2   deltaCREB   COMP1   c-Myb   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCAMK1G promoter sequence
   Search SABiosciences Chromatin IP Primers for CAMK1G

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CAMK1G


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.2   Ensembl cytogenetic band:  1q32.2   HGNC cytogenetic band: 1q32.2

CAMK1G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CAMK1G gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P209757:  view genomic region     (about GC identifiers)

Start:
209,757,045 bp from pter      End:
209,787,284 bp from pter
Size:
30,240 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: KCC1G_HUMAN, Q96NX5 (See protein sequence)
Recommended Name: Calcium/calmodulin-dependent protein kinase type 1G  
Size: 476 amino acids; 53087 Da
Subcellular location: Cytoplasm (By similarity). Golgi apparatus membrane; Peripheral membrane protein (By
similarity). Cell membrane; Peripheral membrane protein (By similarity)
Sequence caution: Sequence=CAB41259.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CAMK1G:
2JAM (3D)    
Secondary accessions: Q86UH5 Q9Y3J7
Alternative splicing: 2 isoforms:  Q96NX5-1   Q96NX5-2   

Explore the universe of human proteins at neXtProt for CAMK1G: NX_Q96NX5

Explore proteomics data for CAMK1G at MOPED 

Post-translational modifications:

  • UniProtKB: May be prenylated on Cys-473 (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96NX5

  • 4/12 DME Specific Peptides for CAMK1G (Q96NX5) (see all 12)
     GGELFDR  ENEIAVL  YVAPEVL  QIQKNFA 

    CAMK1G Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CAMK1G Protein Expression
    REFSEQ proteins: NP_065172.1  
    ENSEMBL proteins: 
     ENSP00000009105   ENSP00000392173   ENSP00000354861  

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    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005737cytoplasm ----
    GO:0005886plasma membrane IEA--
    GO:0005954calcium- and calmodulin-dependent protein kinase complex IEA--
    GO:0012505endomembrane system ----

    CAMK1G for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    IUPHAR Guide to PHARMACOLOGY protein family classification: calcium/calmodulin-dependent protein kinase IG 
    CAMK1 family

    5/6 InterPro protein domains (see all 6):
     IPR017441 Protein_kinase_ATP_BS
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_cat_dom

    Graphical View of Domain Structure for InterPro Entry Q96NX5

    ProtoNet protein and cluster: Q96NX5

    UniProtKB/Swiss-Prot: KCC1G_HUMAN, Q96NX5
    Domain: The autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded
    state with the catalytic domain as a pseudosubstrate (By similarity)
    Similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily
    Similarity: Contains 1 protein kinase domain


    CAMK1G for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: KCC1G_HUMAN, Q96NX5
    Function: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade.
    In vitro phosphorylates transcription factor CREB1 (By similarity)
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein
    Enzyme regulation: Activated by Ca(2+)/calmodulin. Binding of calmodulin is thought to result in a conformational
    change and leads to activation through phosphorylation by CAMKK1 (By similarity)

         Genatlas biochemistry entry for CAMK1G:
    rat calcium/calmodulin dependent protein kinase 1,gamma homolog

         Enzyme Numbers (IUBMB): EC 2.7.11.171 2 EC 2.7.112

         Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004672protein kinase activity ----
    GO:0004674protein serine/threonine kinase activity ----
    GO:0004683calmodulin-dependent protein kinase activity IEA--
    GO:0004713protein tyrosine kinase activity ----
    GO:0005516calmodulin binding IEA--
         
    CAMK1G for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CAMK1G:
     Decreased substrate adherent c  Increased apoptosis 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Camk1g):
     nervous system 

    CAMK1G for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CAMK1G 
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    SwitchGear 3'UTR luciferase reporter plasmidCAMK1G 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CAMK1G About   (see all 8)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    cAMP Pathway0.77
    2NFAT and Cardiac Hypertrophy
    NFAT and Cardiac Hypertrophy0.42
    IGF1R Signaling0.37
    3GPCR Pathway
    Breast Cancer Regulation by Stathmin10.58
    4ErbB signaling pathway
    EGFR Inhibitor Pathway, Pharmacodynamics0.49
    5Neuropathic Pain-Signaling in Dorsal Horn Neurons
    Neuropathic Pain-Signaling in Dorsal Horn Neurons0.47

    5/8 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CAMK1G (see all 8)
        Breast Cancer Regulation by Stathmin1
    Neuropathic Pain-Signaling in Dorsal Horn Neurons
    IGF1R Signaling
    cAMP Pathway
    Activation of cAMP-Dependent PKA

    1 Sino Biological Pathway for CAMK1G 
        EGFR Signaling Pathway

    1 PharmGKB Pathway for CAMK1G
        EGFR Inhibitor Pathway, Pharmacodynamics

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CAMK1G

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/7 Interacting proteins for CAMK1G (Q96NX53 ENSP000000091054) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARRB2P321213I2D: score=1 
    CAMK1DENSP000003681244STRING: ENSP00000368124
    CAMK2BENSP000002586824STRING: ENSP00000258682
    CAMK2DENSP000003397404STRING: ENSP00000339740
    CAMK2GENSP000003190604STRING: ENSP00000319060
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation ----

    CAMK1G for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for CAMK1G (KCC1G)

    3 HMDB Compounds for CAMK1G    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for CAMK1G    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE-- --target--10592235

    Search CenterWatch for drugs/clinical trials and news about CAMK1G / KCC1G

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CAMK1G gene: 
    NM_020439.2  

    Unigene Cluster for CAMK1G:

    Calcium/calmodulin-dependent protein kinase IG
    Hs.199068  [show with all ESTs]
    Unigene Representative Sequence: AK095713
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000009105(uc001hhf.4 uc001hhd.3 uc001hhe.3) ENST00000423146
    ENST00000361322 ENST00000494990
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    Additional mRNA sequence: 

    AF428261.1 AK095713.1 AK289675.1 AL049688.1 AY212935.1 BC032787.1 

    6 DOTS entries:

    DT.40231309  DT.100018751  DT.97784123  DT.100749520  DT.121437584  DT.91965199 

    24/32 AceView cDNA sequences (see all 32):

    AY212935 NM_020439 BI821474 CB154014 BM547443 BI824483 BG170935 BX493511 
    AL049688 BI834635 BU149661 BC032787 AW016039 CK822988 AK095713 BM921532 
    CK822987 BI772626 BQ086330 BQ102407 AF428261 BI753035 BM807335 BI084101 

    GeneLoc Exon Structure

    5/10 Alternative Splicing Database (ASD) splice patterns (SP) for CAMK1G (see all 10)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b · 11c ·
    SP1:                                      -                       -           -                       -                 -                                       
    SP2:              -                       -                       -           -                       -                 -                                       
    SP3:                                      -                       -           -                       -                 -                                       
    SP4:              -                       -                       -           -                       -     -           -                                       
    SP5:              -                       -                                   -                                                                                 

    ExUns: 11d ^ 12 ^ 13
    SP1:  -               
    SP2:  -               
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for CAMK1G

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CAMK1G expression in normal human tissues (normalized intensities)      CAMK1G embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCAGTGTTG
    CAMK1G Expression
    About this image


    CAMK1G expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/31 selected tissues (see all 31) fully expand
     
     Brain (Nervous System)    fully expand to see all 21 entries
             Thalamus
             postcentral gyrus   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Pancreas (Endocrine System)    fully expand to see all 3 entries
             Islets of Langerhans
             Posterior foregut-like cells ( A scalable, suspension protocol for derivation of...
             pancreas ; exocrine glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             colon ; peripheral nerve/ganglion   
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   

    See CAMK1G Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CAMK1G

    SOURCE GeneReport for Unigene cluster: Hs.199068

    UniProtKB/Swiss-Prot: KCC1G_HUMAN, Q96NX5
    Tissue specificity: Mainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver.
    Strongly expressed in forebrain neocortex, striatum and limbic system

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CAMK1G

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CAMK1G gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Camk1g1 , 5 calcium/calmodulin-dependent protein kinase I gamma1, 5 87.89(n)1
    92.23(a)1
      1 (97.74 cM)5
    2153031  NM_144817.21  NP_659066.11 
     1933463465 
    chicken
    (Gallus gallus)
    Aves CAMK1G1 calcium/calmodulin-dependent protein kinase IG 74.02(n)
    79.69(a)
      419859  XM_417986.3  XP_417986.3 
    lizard
    (Anolis carolinensis)
    Reptilia CAMK1G6
    Uncharacterized protein
    64(a)
    1 ↔ 1
    4(125834990-125893150)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc731552 hypothetical protein MGC73155 75.74(n)   393802  BC060911.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CaMKI3 protein amino acid phosphorylation
    calmodulin-dependent more
    57(a)   102C1   --
    worm
    (Caenorhabditis elegans)
    Secernentea cmk-13   -- 57(a)   IV(1824532-1833603)   --


    ENSEMBL Gene Tree for CAMK1G (if available)
    TreeFam Gene Tree for CAMK1G (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CAMK1G gene
    PNCK2  PSKH22  PHKG22  CAMK2A2  CAMK1D2  PSKH12  CAMK42  CAMK2D2  
    PHKG12  CAMKV2  CAMK2G2  CAMK2B2  CAMK12  
    18/60 SIMAP similar genes for CAMK1G using alignment to 2 protein entries:     KCC1G_HUMAN (see all proteins) (see all similar genes):
    CAMK1D    CAMK1    PNCK    BRSK2    PSKH2    NUAK1
    PSKH1    RPS6KA4    DCLK3    PRKAA2    PRKAA1    MYLK
    CAMK4    CHEK2    RPS6KA5    RPS6KA1    MARK2    MARK1

    CAMK1G for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/789 SNPs in CAMK1G are shown (see all 789)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0406014
    A breast infiltrating ductal carcinoma sample4--see VAR_0406012 A T mis40--------
    rs741579801,2
    C--209755157(+) AATTCG/ATAGAA 1 -- us2k14Minor allele frequency- A:0.10WA NA EA 360
    rs1827418481,2
    --209755185(+) TCCCCA/GTATAG 1 -- us2k10--------
    rs557093811,2
    C,F--209755202(+) GGGCAG/ATGCAG 1 -- us2k14Minor allele frequency- A:0.14CSA WA NA EA 359
    rs1116136991,2
    F--209755230(+) TATAAG/AGGCAC 1 -- us2k12Minor allele frequency- A:0.04CSA WA 120
    rs1873725181,2
    --209755245(+) TCCATC/TCACAA 1 -- us2k10--------
    rs1436765741,2
    C--209755273(+) CTTCAC/TCACCT 1 -- us2k10--------
    rs1481122461,2
    C--209755316(+) TGGTGA/GTTAGC 1 -- us2k10--------
    rs1418668411,2
    --209755364(+) AGACTA/GTGGCA 1 -- us2k10--------
    rs561654131,2
    C,F--209755450(+) GTCTCG/ACTCCA 1 -- us2k15Minor allele frequency- A:0.14NA CSA WA EA 361

    HapMap Linkage Disequilibrium report for CAMK1G (209757045 - 209787284 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CAMK1G:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2672471CNV Deletion23128226

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 614994    OMIM disorders: --

    3 diseases for CAMK1G:    About MalaCards
    van der woude syndrome    neuronitis    breast cancer


    CAMK1G for disorders           About GeneDecksing

    Genetic Association Database (GAD): CAMK1G
    Human Genome Epidemiology (HuGE) Navigator: CAMK1G (3 documents)

    Export disorders for CAMK1G gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CAMK1G gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with CAMK1G)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of CLICK-III/CaMKIgamma, a novel membrane-anchored neuronal Ca2+/calmodulin-dependent protein kinase (CaMK). (PubMed id 12637513)1, 2, 3 Takemoto-Kimura S.... Bito H. (2003)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. A preliminary gene map for the Van der Woude syndrome critical region derived from 900 kb of genomic sequence at 1q32-q41. (PubMed id 10645953)1, 2 Schutte B.C....Murray J.C. (2000)
    6. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    7. Genome-wide association analyses in Han Chinese identi fy two new susceptibility loci for amyotrophic lateral sclerosis. (PubMed id 23624525)1 Deng M....Zhang X. (2013)
    8. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    9. Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 57172 HGNC: 14585 AceView: CAMK1G Ensembl:ENSG00000008118 euGenes: HUgn57172
    ECgene: CAMK1G H-InvDB: CAMK1G

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CAMK1G Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CAMK1G gene:
    Search GeneIP for patents involving CAMK1G

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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