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CALM1 Gene

protein-coding GIFtS: 69

GC14P089933

calmodulin 1 (phosphorylase kinase, delta)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CALML2)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CALM ^³
CALML2 ^², ³
CAM ^³
CAM1 ^³
CAM2 ^³
CAM3 ^³
CAMB ^³
CAMC ^³
CAMI ^¹, ²
CAMIII ^³
CaM ^³
DD132 ^¹, ²
PHKD ^¹, ², ⁵

Descriptions
calmodulin 1 ^²
calmodulin 1 (phosphorylase kinase, delta) ^²
phosphorylase kinase, delta subunit ^²

External Ids
HGNC: 1442¹
Entrez Gene: 801²
UniProtKB: P62158³
Ensembl: ENSG00000198668⁷

Search outside databases for aliases for CALM1 gene

Previous GC identifers: GC14P088369 GC14P084679 GC14P088853

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CALM1:

Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members

have been found. They are identified by their occurrence in the cytosol or on membranes facing the

cytosol and by a high affinity for calcium. Calmodulin contains 149 amino acids and has 4

calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in

signal transduction and the synthesis and release of neurotransmitters.[supplied by OMIM]

UniProtKB/Swiss-Prot: CALM_HUMAN, P62158

Function: Calmodulin mediates the control of a large number of enzymes and other proteins by

Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of

protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic

pathway that regulates the centrosome cycle and progression through cytokinesis

Gene Wiki entry for CALM1 (Calmodulin_1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CALM1 gene

Entrez Gene cytogenetic band: 14q24-q31 Ensembl cytogenetic band: 14q32.11 HGNC cytogenetic band: 14q24-q31

CALM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P089933: (about GC identifiers)

Start:	89,933,126 bp from pter
End:	89,944,363 bp from pter
Size:	11,238 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CALM_HUMAN, P62158 (See protein sequence)

Recommended Name: Calmodulin

Size: 149 amino acids; 16838 Da

Subunit: Interacts with MYO1C (By similarity). Interacts with CEP97, CEP110, TTN/titin and SRY

Subcellular location: Spindle. Note=Distributed throughout the cell during interphase, but during

mitosis becomes dramatically localized to the spindle poles and the spindle microtubules

Miscellaneous: This protein has four functional calcium-binding sites

Sequence caution: Sequence=CAA36839.1; Type=Erroneous gene model prediction;

PDB structures from and Proteopedia :

1AJI (3D)

1CDL (3D)

1CLL (3D)

1CTR (3D)

1IWQ (3D)

1J7O (3D)

1J7P (3D)

1K90 (3D)

1K93 (3D)

1L7Z (3D)

1LVC (3D)

1NKF (3D)

1PK0 (3D)

1S26 (3D)

1SK6 (3D)

1SW8 (3D)

1WRZ (3D)

1XFU (3D)

1XFV (3D)

1XFW (3D)

1XFX (3D)

1XFY (3D)

1XFZ (3D)

1Y6W (3D)

1YR5 (3D)

1YRT (3D)

1YRU (3D)

1ZOT (3D)

1ZUZ (3D)

2BE6 (3D)

2F3Y (3D)

2F3Z (3D)

2HF5 (3D)

2I08 (3D)

2JZI (3D)

2K0E (3D)

2K0F (3D)

2K0J (3D)

2K61 (3D)

2R28 (3D)

2V01 (3D)

2V02 (3D)

2VAY (3D)

2WEL (3D)

3BYA (3D)

3DVE (3D)

3DVJ (3D)

3DVK (3D)

3DVM (3D)

3G43 (3D)

Secondary accessions: P02593 P70667 P99014 Q13942 Q53S29 Q61379 Q61380 Q96HK3

Post-translational modifications:

Ubiquitination results in a strongly decreased activity (By similarity)¹

Phosphorylation results in a decreased activity (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_008819.1

ENSEMBL proteins:

ENSP00000349467

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant CALM1 Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Enzo Life Sciences proteins for CALM1
	Recombinant Proteins from Abcam (Calmodulin)
	Browse Abnova for Human Recombinant Proteins

OriGene Purified Recombinant Human Protein: CALM1

Antibodies for CALM1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of CALM1
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Calmodulin), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CALM1)
	Novus Biologicals Antibody for CALM1

Assays for CALM1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P62158

ProtoNet protein and cluster: P62158

UniProtKB/Swiss-Prot: CALM_HUMAN, P62158

Similarity: Belongs to the calmodulin family

Similarity: Contains 4 EF-hand domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CALM1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CALM1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006888

Applied Biosystems Silencer® siRNAs for CALM1

Sigma-Aldrich siRNA for CALM1

Sigma-Aldrich shRNA Panels and shRNA for CALM1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006888
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006888
untagged cDNA clone in CMV expression vector: NM_006888

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006888

UniProtKB/Swiss-Prot: CALM_HUMAN, P62158

Function: Calmodulin mediates the control of a large number of enzymes and other proteins by

Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of

protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic

pathway that regulates the centrosome cycle and progression through cytokinesis

Genatlas biochemistry entry for CALM1:

calmodulin 1,calcium modulated protein

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/23 Sigma-Aldrich "Your Favorite Gene" Pathways for CALM1 (Your Favorite Gene powered by Ingenuity) (see all 23 )

Role of NFAT in Regulation of the Immune Response
CREB Signaling in Neurons
Glutamate Receptor Signaling
Chemokine Signaling
fMLP Signaling in Neutrophils

GeneDecks CALM1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for CALM1

5/118 Interacting proteins for CALM1 (P62158^{1, 2} ENSP00000349467³) via UniProtKB, MINT, and/or STRING (see all 118 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CACNA1C	Q13936¹, ENSP00000266376³	EBI-397435, EBI-1038838 STRING (score=.914)
CAMK2A	Q9UQM7¹, ENSP00000305090³	EBI-397435, EBI-1383687 STRING (score=.8)
ARRB1	P49407¹	EBI-397435, EBI-743313
ARRB2	P32121¹	EBI-397435, EBI-714559
CEP110	O43303¹	EBI-397435, EBI-1566217

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CALM1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CALM1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CALM1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006888

Sigma-Aldrich siRNA for CALM1

Sigma-Aldrich shRNA Panels and shRNA for CALM1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006888

REFSEQ mRNAs for CALM1 gene:

NM_006888.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006888

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006888
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006888
                                 untagged cDNA clone in CMV expression vector: NM_006888

Additional cDNA sequence:

AK289937.1 AY189287.1 BC000454.2 BC007965.2 BC008597.1 BC011834.2 BC042831.1 BT006818.1

BX537677.1 BX648223.1 CR590380.1 CR591035.1 CR592381.1 CR595745.1 CR604747.1 CR618763.1

CR619428.1 CR626701.1 L37715.1 M27319.1 U16850.1

24/39 DOTS entries (see all 39 ):

DT.95203091 DT.100888491 DT.92463189 DT.91929905 DT.100888511 DT.120780285 DT.95111250 DT.120780225

DT.120780237 DT.100034559 DT.95203069 DT.120780231 DT.120780232 DT.95203107 DT.100888490 DT.95203053

DT.100888476 DT.100888499 DT.120780329 DT.95203059 DT.120780148 DT.120780241 DT.120780333 DT.92463188

24/1535 AceView cDNA sequences (see all 1535 ):

BE552127 CB163664 AA236541 H77337 BQ648519 N42353 BQ644110 AI744389

F08797 AA778347 H60495 AI498635 N66809 BP374712 BI438647 BM314573

AW510546 AA460374 BU734925 AA911773 T32219 AW051407 BM838032 CN480740

highest scoring ESTs for CALM1:

AA070961 AA070962 AA082837 AA085590 AA093133 AA205309 AA216057 AA236541 AA236725 AA278819

Unigene Cluster for CALM1:

Calmodulin 1 (phosphorylase kinase, delta)

Hs.282410 [show with all ESTs]

Unigene Representative Sequence: NM_006888

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CALM1 (see all 6 )

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	^	8a	·	8b
SP1:			-		-				-				-				-				-
SP2:													-				-				-
SP3:													-				-
SP4:																					-
SP5:			-

About this scheme

ECgene alternative splicing isoforms for CALM1

1 Ensembl transcript including schematic representation:

ENST00000356978

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CALM1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CALM1

¹ / ² / ³

17 probe-sets matching CALM1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41143_at²^{, 3}	U95-A	1	1.00	1.00	0.81	1.08	U12022	0.20	1.00	0.72	1
955_at²^{, 3}	U95-A	1	1.00	1.00	0.89	1.07	HG1862-HT1897	0.20	1.00	0.72	1
41288_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.98	AL036744	0.60	1.00	0.82	1
51680_at²^{, 3}	U95-C	1	1.00	1.00	0.98	1.13	AW023159	0.80	1.00	0.91	1
41144_g_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.74	U12022	0.20	1.00	0.72	1
213688_at²^{, 3}	U133-A	1	1.00	1.00	--	--	N25325	0.80	1.00	0.91	1
211985_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI653730	0.60	1.00	0.82	1
211984_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI653730	0.60	1.00	0.82	1
209563_x_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BC000454	0.80	1.00	0.91	1
200655_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_006888	0.40	1.00	0.76	1
200653_s_at²^{, 3}	U133-A	2	1.00	0.95	--	--	M27319	0.80	1.00	0.91	1
213688_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211985_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
211984_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
209563_x_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200655_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
200653_s_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--

GeneDecks CALM1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.282410
Expression variation in blood from EXPOLDB for CALM1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CALM1 gene from 5/14 species (see all 14 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CALM1¹	--	calmodulin 1 (phosphorylase kinase, delta)	95.97(n) 100(a)	480416 XM_537537.2 XP_537537.1
chimpanzee (Pan troglodytes)	CALM2¹	--	calmodulin 2 (phosphorylase kinase, delta)	85.23(n) 100(a)	459213 XM_515457.2 XP_515457.1
cow (Bos taurus)	CALM2¹	--	calmodulin 2 (phosphorylase kinase, delta)	84.34(n) 98.66(a)	326597 XM_001250668.1 XP_001250669.1
mouse (Mus musculus)	Calm1^{1, 5}	12⁵	calmodulin 1^{1, 5}	92.84(n)¹ 100(a)¹	12313¹ NM_009790.4¹ NP_033920.1¹ AI256814⁵ AI326259⁵ (see all 58)
chicken (Gallus gallus)	RCJMB04_24e7¹	--	calmodulin 2 (phosphorylase kinase, delta)	83.89(n) 98.66(a)	395855 NM_205005.1 NP_990336.1

About this table Species with no ortholog for CALM1

ENSEMBL Gene Tree for CALM1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CALM1 gene

CALM2¹ ² CALM3¹ ²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/91 NCBI SNPs in CALM1 are shown (see all 91 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 51)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs3179089^1,2	A,C,F,H	89943165(+)	`GGATCC/GTGTCT`	1	--	ut3¹ ese³		5		MN EU EA WA	596
--	rs5871^1,2	A,C,F,H	89941231(+)	`TTTGTT/CTAGTA`	1	--	ut3¹ ese³		14		NS MN EU EA WA	1100
	rs3814845^1,2	C,F,H	89942258(-)	`AACTTG/CGGAAA`	1	--	ut3¹ ese³ trp³		8		EA MN EU WA	2340
	rs1059296^1,2	C,F,H	89941896(+)	`TGGACA/GTGTAG`	1	--	ut3¹ ese³		8		MN NA EU EA WA	746
	rs3814843^1,2	C,F,H	89942766(-)	`AGCAGA/CAGCAC`	1	--	ut3¹ ese³		4		EU EA WA	402
	rs3814847^1,2	C,F,H	89931789(-)	`TTCTGG/CTTTCA`	1	--	ng5¹		4		EU EA WA	418
	rs1058903^1,2	C,F,H	89943551(+)	`TTGAGC/TGAGGC`	1	--	ut3¹		10		EA MN EU WA	2334
	rs11621831^1,2	C,H	89944791(+)	`ATTTAG/AGACCT`	1	--	ng3¹		4		EU EA WA	418
--	rs7148581^1,2	C	89932956(+)	`GCGTAG/TGGCCG`	1	--	ng5¹		0	--	--	--	--
--	rs12886342^1,2	A	89933242(+)	`GCAGCA/GGCATC`	1	--	ut5¹ ese³		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for CALM1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 114180

1 PharmGKB disease relationship for CALM1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872 12730115

About this table

Human Gene Mutation Database: CALM1
Genetic Association Database: CALM1
Human Genome Epidemiology Navigator: CALM1 (9 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/205 PubMed articles for CALM1 gene (see all 205 ):

Isolation and nucleotide sequence of a cDNA encoding human calmodulin. (PubMed id 6385987)^{2, 3, 4} Wawrzynczak E.J. and Perham R.N. (1984)
The CALM1 core promoter polymorphism is not associated with hip osteoarthritis in a United Kingdom Caucasian population. (PubMed id 16359877)^{3, 6} Loughlin J....Chapman K. (2006)
A functional single nucleotide polymorphism in the core promoter region of CALM1 is associated with hip osteoarthritis in Japanese. (PubMed id 15746150)^{3, 6} Mototani H....Ikegawa S. (2005)
Insights into voltage-gated calcium channel regulation from the structure of the CaV1.2 IQ domain-Ca2+/calmodulin complex. (PubMed id 16299511)^{3, 4} Van Petegem F.... Minor D.L. Jr. (2005)
Defective calmodulin-mediated nuclear transport of the sex- determining region of the Y chromosome (SRY) in XY sex reversal. (PubMed id 15746192)^{3, 4} Sim H.... Harley V.R. (2005)
Characterization of the human CALM2 calmodulin gene and comparison of the transcriptional activity of CALM1, CALM2 and CALM3. (PubMed id 9681195)^{3, 4} Toutenhoofd S.L.... Strehler E.E. (1998)
Structure of the human CALM1 calmodulin gene and identification of two CALM1-related pseudogenes CALM1P1 and CALM1P2. (PubMed id 7925473)^{3, 4} Rhyner J.A.... Strehler E.E. (1994)
Structural organization of the human CaMIII calmodulin gene. (PubMed id 2223880)^{3, 4} Koller M.... Strehler E.E. (1990)
Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)³ Luke M.M....Psaty B.M. (2009)
Association of the CALM1 core promoter polymorphism with knee osteoarthritis in patients of Greek origin. (PubMed id 18452398)³ Poulou M....Tzetis M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 801	HGNC: 1442	AceView: CALM1	Ensembl:ENSG00000198668	euGenes: HUgn801
ECgene: CALM1	H-InvDB: CALM1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CALM1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for CALM1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CALM1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CALM1-related products

	Millipore Custom Antibody & Bulk Services
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Antibodies for CALM1

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
CALM1 Gene at Home site.
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CALM1 Gene

protein-coding GIFtS: 69

Aliases &
Descriptions
for CALM1

Summaries
for CALM1

Genomic Location
for CALM1

Proteins
for CALM1

Protein Domains/
Families
for CALM1

Gene Function
for CALM1

Pathways & Interactions
for CALM1

Drugs & Compounds
for CALM1

Transcripts
for CALM1

Expression
for CALM1

Orthologs
for CALM1

Paralogs
for CALM1

SNPs/Variants
for CALM1

Disorders & Mutations
for CALM1

Medical News
for CALM1

Publications
for CALM1

Search for CALM1

Genome Databases showing CALM1

Other Databases showing CALM1

Specialized Databases showing CALM1

Licensable Technologies
for CALM1

Services
for CALM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CALM1 Gene

protein-coding GIFtS: 69

Aliases & Descriptionsfor CALM1

Summariesfor CALM1

Genomic Locationfor CALM1

Proteinsfor CALM1

Protein Domains/Familiesfor CALM1

Gene Functionfor CALM1

Pathways & Interactionsfor CALM1

Drugs & Compoundsfor CALM1

Transcriptsfor CALM1

Expression for CALM1

Orthologsfor CALM1

Paralogsfor CALM1

SNPs/Variantsfor CALM1

Disorders & Mutationsfor CALM1

Medical Newsfor CALM1

Publicationsfor CALM1

Search for CALM1

Genome Databases showing CALM1

Other Databases showing CALM1

Specialized Databases showing CALM1

Licensable Technologiesfor CALM1

Servicesfor CALM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CALM1

Summaries
for CALM1

Genomic Location
for CALM1

Proteins
for CALM1

Protein Domains/
Families
for CALM1

Gene Function
for CALM1

Pathways & Interactions
for CALM1

Drugs & Compounds
for CALM1

Transcripts
for CALM1

Expression
for CALM1

Orthologs
for CALM1

Paralogs
for CALM1

SNPs/Variants
for CALM1

Disorders & Mutations
for CALM1

Medical News
for CALM1

Publications
for CALM1

Licensable Technologies
for CALM1

Services
for CALM1