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CALHM2 Gene

protein-coding   GIFtS: 46
GCID: GC10M105206

Calcium Homeostasis Modulator 2

(Previous names: family with sequence similarity 26, member B)
(Previous symbol: FAM26B)
Alzheimer's & Parkinson's Diseases Congress
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Calcium Homeostasis Modulator 21 2
FAM26B1 2 3 5
Family With Sequence Similarity 26, Member B1 2
Calcium Homeostasis Modulator Protein 22
Protein FAM26B3

External Ids:    HGNC: 234931   Entrez Gene: 510632   Ensembl: ENSG000001381727   OMIM: 6122355   UniProtKB: Q9HA723   

Export aliases for CALHM2 gene to outside databases

Previous GC identifers: GC10M105197 GC10M098837


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CALHM2 Gene:
CALHM2 (calcium homeostasis modulator 2) is a protein-coding gene. Diseases associated with CALHM2 include alzheimer's disease. An important paralog of this gene is CALHM1.

UniProtKB/Swiss-Prot: CAHM2_HUMAN, Q9HA72
Function: Pore-forming subunit of a voltage-gated ion channel (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CALHM2 gene promoter:
         AhR   GR   Pax-5   GR-beta   Pax-2   LCR-F1   YY1   GATA-2   HEN1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCALHM2 promoter sequence
   Search Chromatin IP Primers for CALHM2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CALHM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.33   Ensembl cytogenetic band:  10q24.33   HGNC cytogenetic band: 10q24.33

CALHM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CALHM2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M105206:  view genomic region     (about GC identifiers)

Start:
105,206,543 bp from pter      End:
105,212,660 bp from pter
Size:
6,118 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CAHM2_HUMAN, Q9HA72 (See protein sequence)
Recommended Name: Calcium homeostasis modulator protein 2  
Size: 323 amino acids; 36175 Da
Secondary accessions: D3DR94 O95893 Q6ZUV9
Alternative splicing: 3 isoforms:  Q9HA72-1   Q9HA72-2   Q9HA72-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CALHM2: NX_Q9HA72

Explore proteomics data for CALHM2 at MOPED


See CALHM2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_057000.2  
ENSEMBL proteins: 
 ENSP00000358803   ENSP00000260743   ENSP00000376927  

CALHM2 Human Recombinant Protein Products:

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OriGene Purified Protein for CALHM2
OriGene Protein Over-expression Lysate for CALHM2
OriGene MassSpec for CALHM2
OriGene Custom Protein Services for CALHM2
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Novus Biologicals CALHM2 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for CALHM2

CALHM2 Antibody Products:

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OriGene Custom Antibody Services for CALHM2
Novus Biologicals CALHM2 Antibody
Abcam antibodies for CALHM2
Cloud-Clone Corp. Antibodies for CALHM2
Search ThermoFisher Antibodies for CALHM2
Search LSBio for Antibodies for CALHM2

CALHM2 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for CALHM2
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CALHM2
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for CALHM2
Cloud-Clone Corp. CLIAs for CALHM2


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q9HA72

UniProtKB/Swiss-Prot: CAHM2_HUMAN, Q9HA72
Similarity: Belongs to the FAM26 family


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CAHM2_HUMAN, Q9HA72
Function: Pore-forming subunit of a voltage-gated ion channel (By similarity)

Animal Models:

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CALHM2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CALHM2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CALHM2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CALHM2

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat CALHM2 using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate CALHM2:
hsa-miR-374a* hsa-miR-3163
SwitchGear 3'UTR luciferase reporter plasmidCALHM2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CALHM2
Predesigned siRNA for gene silencing in human, mouse, rat CALHM2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CALHM2

Clone
Products:
     
OriGene clones in human, mouse for CALHM2 (see all 6)
OriGene ORF clones in mouse, rat for CALHM2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CALHM2 (NM_015916)
Sino Biological Human cDNA Clone for CALHM2
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CALHM2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CALHM2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CALHM2
Browse ESI BIO Cell Lines and PureStem Progenitors for CALHM2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CALHM2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CAHM2_HUMAN, Q9HA72: Membrane; Multi-pass membrane protein (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane3
golgi apparatus2
cytosol1
mitochondrion1
nucleus1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--

CALHM2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CALHM2
Interactions:

    Search GeneGlobe Interaction Network for CALHM2

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for CALHM2 (Q9HA723 ENSP000002607434) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
MAPK3P273613, ENSP000002630254I2D: score=1 STRING: ENSP00000263025
PLSCR1O151623I2D: score=1 
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006811ion transport IEA--

CALHM2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CALHM2 (CAHM2)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CALHM2 gene: 
NM_015916.4  

Unigene Cluster for CALHM2:

Calcium homeostasis modulator 2
Hs.241545  [show with all ESTs]
Unigene Representative Sequence: AK125276
8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000369788(uc001kxc.3 uc001kxb.3) ENST00000260743(uc001kxa.3)
ENST00000494180 ENST00000463878 ENST00000480642 ENST00000461631 ENST00000474797
ENST00000393235(uc001kxd.1)

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CALHM2 using miScript Target Protectors
2 qRT-PCR Assays for microRNAs that regulate CALHM2:
hsa-miR-374a* hsa-miR-3163
SwitchGear 3'UTR luciferase reporter plasmidCALHM2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CALHM2
Predesigned siRNA for gene silencing in human, mouse, rat CALHM2
Clone
Products:
     
OriGene clones in human, mouse for CALHM2 (see all 6)
OriGene ORF clones in mouse, rat for CALHM2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CALHM2 (NM_015916)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CALHM2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CALHM2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CALHM2
OriGene qSTAR qPCR primer pairs in human, mouse for CALHM2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CALHM2
  QuantiTect SYBR Green Assays in human, mouse, rat CALHM2
  QuantiFast Probe-based Assays in human, mouse, rat CALHM2

Additional mRNA sequence: 

AF131810.1 AK022195.1 AK125276.1 BC000039.2 NR_024552.1 NR_046344.1 

11 DOTS entries:

DT.315666  DT.95284754  DT.101958092  DT.91752949  DT.121299076  DT.100784236  DT.100784240  DT.91666285 
DT.95170314  DT.97844790  DT.203101 

Selected AceView cDNA sequences (see all 176):

AU098407 AI086876 CD365394 BQ029260 AK125276 AI283783 BQ005206 BM693426 
AI005028 AI247576 BG697889 BU625595 CF265181 BP376649 BP377505 AI697515 
BP873141 CA432041 BP380146 BM719626 AL602592 CF272443 BC000039 BM551755 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for CALHM2 (see all 13)    About this scheme

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d · 2e · 2f · 2g ^ 3a · 3b · 3c · 3d ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c · 6d · 6e ^ 7
SP1:              -     -     -     -     -                 -     -                 -     -     -                                                               
SP2:                                                        -     -     -           -     -     -     -     -     -     -                                       
SP3:                                                        -                       -     -     -     -     -     -     -                                       
SP4:                                                        -     -     -           -     -     -     -     -     -     -                             -         
SP5:              -     -     -     -     -     -     -     -     -     -                                                                                       


ECgene alternative splicing isoforms for CALHM2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CALHM2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TATCTAGCTG
CALHM2 Expression
About this image

CALHM2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CALHM2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.241545
    Custom PCR Arrays for CALHM2
Primer
Products:
OriGene qPCR primer pairs and template standards for CALHM2
OriGene qSTAR qPCR primer pairs in human, mouse for CALHM2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CALHM2
QuantiTect SYBR Green Assays in human, mouse, rat CALHM2
QuantiFast Probe-based Assays in human, mouse, rat CALHM2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CALHM2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for CALHM2 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Calhm21 , 5 calcium homeostasis modulator 21, 5 87.33(n)1
92.83(a)1
  19 (39.28 cM)5
726911  NM_133746.51  NP_598507.31 
 471053535 
chicken
(Gallus gallus)
Aves CALHM21 calcium homeostasis modulator 2 77.74(n)
79.62(a)
  770753  XM_004942259.1  XP_004942316.1 
lizard
(Anolis carolinensis)
Reptilia CALHM26
calcium homeostasis modulator 2
73(a)
1 ↔ 1
3(40697056-40700518)
tropical clawed frog
(Xenopus tropicalis)
Amphibia MGC761652 hypothetical protein MGC76165 74.27(n)    BC063213.1 
zebrafish
(Danio rerio)
Actinopterygii calhm21 calcium homeostasis modulator 2 60.85(n)
60.4(a)
  368657  NM_001003458.1  NP_001003458.1 
worm
(Caenorhabditis elegans)
Secernentea clhm-16
Protein CLHM-1 (clhm-1) mRNA, complete cds
21(a)
1 → many
II(6868942-6870839) WBGene00016626


ENSEMBL Gene Tree for CALHM2 (if available)
TreeFam Gene Tree for CALHM2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CALHM2 gene
CALHM12  CALHM32  FAM26D2  FAM26F2  FAM26E2  
4 SIMAP similar genes for CALHM2 using alignment to 1 protein entry:     CAHM2_HUMAN:
FAM26D    CALHM1    CALHM3    FAM26F

CALHM2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CALHM2 (see all 134)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 10 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1403594331,2
--105206551(+) TTTTAA/GTAAGA 3 -- ut31 nc-transcript-variant0--------
rs1847155481,2
--105206633(+) CACTGC/TTGCGC 3 -- ut31 nc-transcript-variant0--------
rs65801,2
C,F,O,A,H--105206874(+) CCAAGC/TAGTGC 3 -- ut31 nc-transcript-variantese325Minor allele frequency- N:0.00MN EA NA NS CSA WA EU 3327
rs2014272431,2
C--105206948(+) GGGGCC/TGCGCC 4 A syn10--------
rs617449461,2
F--105207094(+) AATCAC/GTTCCT 4 L V mis11Minor allele frequency- G:0.44NS 18
rs2004583231,2
--105207101(+) TCCTCA/GTCATC 4 D syn10--------
rs22326631,2
C,F,A,H--105207176(-) ACGGCC/TGAGGT 4 A syn1 ese318Minor allele frequency- T:0.09NS EA NA CSA WA EU 7259
rs1998349451,2
--105207183(+) CCGTGC/TGCTGG 4 H R mis10--------
rs1439536191,2
C,F--105207194(+) AACAGC/TTGGTC 4 Q syn12Minor allele frequency- T:0.00NA EU 5875
rs1996969921,2
C--105207196(+) CAGCTA/GGTCCT 4 Q * stg10--------

HapMap Linkage Disequilibrium report for CALHM2 (105206543 - 105212660 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CALHM2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv524966CNV Loss19592680
nsv518987CNV Loss19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CALHM2
DNA2.0 Custom Variant and Variant Library Synthesis for CALHM2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612235    OMIM disorders: --

1 disease for CALHM2:    
About MalaCards
alzheimer's disease


CALHM2 for disorders           About GeneDecksing


Congresses - knowledge worth sharing:
Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
Genetic Association Database (GAD): CALHM2
Human Genome Epidemiology (HuGE) Navigator: CALHM2 (2 documents)

Export disorders for CALHM2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CALHM2 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with CALHM2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. (PubMed id 18585350)1, 2, 3 Dreses-Werringloer U....Marambaud P. (Cell 2008)
  2. Genetic association between CALHM1, 2, and 3 polymorphisms and Alzheimer's disease in a Japanese population. (PubMed id 20164573)1, 4 Shibata N....Arai H. (J. Alzheimers Dis. 2010)
  3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
  7. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
  8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1 Yu W.... Gibbs R.A. (Genome Res. 1997)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 51063 HGNC: 23493 AceView: FAM26B Ensembl:ENSG00000138172 euGenes: HUgn51063
ECgene: CALHM2 H-InvDB: CALHM2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CALHM2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CALHM2 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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