V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

CALCRL Gene

protein-coding GIFtS: 60

GC02M187918

calcitonin receptor-like
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CGRPR ^¹, ², ³, ⁵
CRLR ^¹, ², ⁵

Descriptions
CGRP type 1 receptor ^³
Calcitonin receptor-like receptor ^³
calcitonin receptor-like ^²

External Ids
HGNC: 16709¹
Entrez Gene: 10203²
UniProtKB: Q16602³
Ensembl: ENSG00000064989⁷

Search outside databases for aliases for CALCRL gene

Previous GC identifers: GC02M186419 GC02M186892 GC02M188171 GC02M188412 GC02M188035

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CALRL_HUMAN, Q16602

Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for

adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is

mediated by G proteins which activate adenylyl cyclase

Gene Wiki entry for CALCRL

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CALCRL gene

Entrez Gene cytogenetic band: 2q32.1 Ensembl cytogenetic band: 2q32.1 HGNC cytogenetic band: 2q21.1-q21.3

CALCRL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M187918: (about GC identifiers)

Start:	187,916,091 bp from pter
End:	188,021,432 bp from pter
Size:	105,342 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000002.10 NT_005403.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CALRL_HUMAN, Q16602 (See protein sequence)

Recommended Name: Calcitonin gene-related peptide type 1 receptor precursor

Size: 461 amino acids; 52929 Da

Subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3 (By similarity)

Subcellular location: Cell membrane; Multi-pass membrane protein

Secondary accessions: A8K6G5 A8KAD3 Q53S02 Q53TS5

REFSEQ proteins: NP_005786.1

ENSEMBL proteins:

ENSP00000376177 ENSP00000386972 ENSP00000387190 ENSP00000386599

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant CALCRL Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (CRLR)
	Human Recombinant Proteins from Abnova (CALCRL)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	7818539

About this table

Antibodies for CALCRL:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of CALCRL
	Sigma-Aldrich Antibodies for CALCRL
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (CRLR), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CALCRL)
	Novus Biologicals Antibodies for CALCRL

Assays for CALCRL:

	Invitrogen Assays for CALCRL
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q16602

ProtoNet protein and cluster: Q16602

3 Blocks protein families:

IPB000832 G-protein coupled receptors family 2 (secretin-like)

IPB003287 Calcitonin receptor family signature

IPB003289 Calcitonin gene-related peptide type 1 receptor signature

UniProtKB/Swiss-Prot: CALRL_HUMAN, Q16602

Similarity: Belongs to the G-protein coupled receptor 2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CALCRL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CALCRL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005795

Applied Biosystems Silencer® siRNAs for CALCRL

Sigma-Aldrich siRNA and siRNA Panels for CALCRL

Sigma-Aldrich shRNA Panels and shRNA for CALCRL

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Millipore Clones for the Expression of CALCRL

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005795
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005795
untagged cDNA clone in CMV expression vector: NM_005795

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005795

UniProtKB/Swiss-Prot: CALRL_HUMAN, Q16602

Function: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for

adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is

mediated by G proteins which activate adenylyl cyclase

7 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Calcrl):

	digestive/alimentary	homeostasis/metabolism	immune system	lethality-prenatal/perinatal
muscle	skin/coat/nails

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004948	calcitonin receptor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for CALCRL

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger	TAS	7818539

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for CALCRL:

Antagonist

Compounds for CALCRL available from Tocris Bioscience

Compound	Action	CAS number
CRSP-1	Endogenous central CT receptor agonist	[697327-12-1]
CGRP 8-37 (human)	CGRP1 receptor antagonist	[119911-68-1]
CGRP 8-37 (rat)	CGRP1 receptor antagonist
SUN-B 8155	Non-peptide calcitonin (CT) receptor agonist	[345893-91-6]
CGRP (rat)	Potent vasodilator	[96827-03-1]

About this table

4 Novoseek chemical compound relationships for CALCRL gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
bibn 4096 bs	89.41	4	12183333 (3)
cyclic amp	32.17	2	12630807 (1)
nitric oxide	1.31	5	9516404 (1), 14717924 (1), 19441274 (1)
potassium	0.00	1	9877154 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CALCRL)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CALCRL)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_005795

Sigma-Aldrich siRNA and siRNA Panels for CALCRL

Sigma-Aldrich shRNA Panels and shRNA for CALCRL

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005795

REFSEQ mRNAs for CALCRL gene:

NM_005795.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005795

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005795
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005795
                                 untagged cDNA clone in CMV expression vector: NM_005795

Additional cDNA sequence:

AK291630.1 AK292998.1 AY389506.1 DQ280491.1 L76380.1 U17473.1

9 DOTS entries:

DT.210868 DT.120960866 DT.99949950 DT.120960838 DT.91989109 DT.120960773 DT.120960823 DT.120960762

DT.91742361

24/77 AceView cDNA sequences (see all 77 ):

AA961493 N54728 AA436933 BX646999 NM_005795 AW272754 BX471114 BU677790

AA885023 AI500611 AY389506 BG546194 AI478743 AA975301 CB052425 BQ002778

AI200304 AI682490 BE858956 BX474361 BM665935 U17473 AW337575 BX494141

highest scoring ESTs for CALCRL:

L76380 AL602685 U17473 AA298025 AA298652 AA436933 AA757351 AA885023 AA961493 AA975301

Unigene Cluster for CALCRL:

Calcitonin receptor-like

Hs.470882 [show with all ESTs]

Unigene Representative Sequence: NM_005795

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for CALCRL (see all 11 )

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8a	·	8b	·	8c	^	9	^	10	^	11	^	12	^	13
SP1:							-		-				-				-
SP2:							-						-				-
SP3:							-		-		-		-				-		-		-		-
SP4:													-
SP5:							-		-		-		-				-

About this scheme

ECgene alternative splicing isoforms for CALCRL

4 Ensembl transcripts including schematic representations:

ENST00000392370 ENST00000409998 ENST00000410068 ENST00000410102

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CALCRL expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CALCRL

¹ / ² / ³

9 probe-sets matching CALCRL gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
59645_at²^{, 3}	U95-B	1	1.00	1.00	0.96	0.78	AI741128	0.20	1.00	0.72	1
34995_at²^{, 3}	U95-A	1	1.00	1.00	0.93	1.09	L76380	1.00	1.00	1.00	1
42475_at²^{, 3}	U95-B	1	0.94	1.00	0.96	1.16	T94540	0.20	1.00	0.72	1
234996_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI478743	0.20	1.00	0.72	1
206331_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005795	0.60	1.00	0.82	1
210815_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U17473	0.80	1.00	0.91	1
234996_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
206331_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
210815_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CALCRL for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.470882
Expression variation in blood from EXPOLDB for CALCRL
UniProtKB/Swiss-Prot: CALRL_HUMAN, Q16602
Tissue specificity: Predominantly expressed in the lung and heart

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CALCRL gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CALCRL¹	--	calcitonin receptor-like	90.32(n) 94.59(a)	488438 XM_545560.2 XP_545560.2
chimpanzee (Pan troglodytes)	CALCRL¹	--	calcitonin receptor-like	99.78(n) 100(a)	459810 XM_001161496.1 XP_001161496.1
cow (Bos taurus)	CALCRL¹	--	calcitonin receptor-like	90.53(n) 92.41(a)	527140 XM_605529.3 XP_605529.2
rat (Rattus norvegicus)	Calcrl¹	--	calcitonin receptor-like	86.23(n) 90.87(a)	25029 NM_012717.1 NP_036849.1
mouse (Mus musculus)	Calcrl^{1, 5}	2⁵	calcitonin receptor-like^{1, 5}	85.29(n)¹ 90.22(a)¹	54598¹ NM_018782.1¹ NP_061252.1¹ AB015595⁵ AF146525⁵ (see all 13)

About this table Species with no ortholog for CALCRL

ENSEMBL Gene Tree for CALCRL

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CALCRL gene

CALCR²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/549 NCBI SNPs in CALCRL are shown (see all 549 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 207)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs696092^1,2	A,C,F,H,O	187918459(-)	`CAATCC/TTACTT`	1	--	ut3¹		19		NA EA NS MN EU WA	3411
	rs6753700^1,2	C,F,H	187960656(+)	`TCCAGA/TCTCAA`	1	--	ut5¹ ese³		4		EU EA WA	418
	rs13391909^1,2	C,F,H	187958520(+)	`ACCATA/TAAAAA`	1	F/L	mis¹		4		EU EA WA	406
	rs860859^1,2	A,C,F	187917954(+)	`ATTCAG/ATAAAA`	1	--	ut3¹		3		NA	140
	rs34010553^1,2	C,F	187932205(-)	`TGCTAG/TAAGCT`	1	R/I	mis¹		5		NA EU EA WA	476
	rs13396869^1,2	F,H	187917388(+)	`TGTTTC/AATCCA`	1	--	ut3¹		4		EU EA WA	414
	rs1632282^1,2	A,F	187916257(+)	`TATCAA/GTGAAA`	1	--	ut3¹		1		MN	184
--	rs1511879^1,2	A,C	187915830(+)	`atgagC/Ttaaac`	1	--	ng5¹		0	--	--	--	--
	rs698577^1,2	C,H	187958546(+)	`AAAATA/TCAGGG`	1	Y/N	mis¹		8		MN EU EA WA NA	664
	rs13405040^1,2	F,H	188021827(+)	`GTTTTT/AAAATC`	1	--	ng3¹ tfbs³		4		EU EA WA	396

About this table

HapMap Linkage Disequilibrium images for CALCRL (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 114190

10/13 Novoseek disease relationships for CALCRL gene (see all 13 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pheochromocytoma	45.78	4	17102095 (2), 16178438 (1)
migraine	32.61	6	17508187 (2), 19328288 (1)
glioma	12.67	9	14747444 (4), 16719406 (2), 11943713 (1)
glioblastoma	11.04	2	11943713 (1)
glioblastoma multiforme	10.56	1	16719406 (1)
preeclampsia	4.42	7	19441274 (2), 11905404 (1), 15623815 (1)
pancreatic cancer	0.00	5	17290391 (3), 17363587 (1)
tumors	0.00	3	17020966 (1), 16166333 (1), 17363587 (1)
cardiac hypertrophy	0.00	1	15974887 (1)
heart failure	0.00	4	15300632 (1)

About this table

Genetic Association Database: CALCRL
Human Genome Epidemiology Navigator: CALCRL (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/209 PubMed articles for CALCRL gene (see all 209 ):

A cDNA encoding the calcitonin gene-related peptide type 1 receptor. (PubMed id 8626685)^{2, 3, 4} Aiyar N....Li Y. (1996)
A human orphan calcitonin receptor-like structure. (PubMed id 7818539)^{2, 3, 4} Fluehmann B.... Born W. (1995)
Association study of calcitonin-receptor-like receptor gene in essential hypertension. (PubMed id 15797661)^{1, 3, 6} Sano M....Kokubun S. (2005)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{3, 4} Zhang Z. and Henzel W.J. (2004)
Glycosylation of human CRLR at Asn123 is required for ligand binding and signaling. (PubMed id 11389975)^{1, 3} Kamitani S. and Sakata T. (2001)
Receptor activity modifying proteins interaction with human and porcine calcitonin receptor-like receptor (CRLR) in HEK-293 cells. (PubMed id 11693189)^{1, 3} Aiyar N....Nambi P. (2001)
Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins. (PubMed id 11387328)^{1, 3} Hilairet S....Bouvier M. (2001)
Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalization and recycling. (PubMed id 10882736)^{1, 3} Kuwasako K....Sakata T. (2000)
Assembly and signaling of CRLR and RAMP1 complexes assessed by BRET. (PubMed id 17503773)^{1, 3} Heroux M....Bouvier M. (2007)
The extracellular domain of receptor activity-modifying protein 1 is sufficient for calcitonin receptor-like receptor function. (PubMed id 12574158)^{1, 3} Fitzsimmons T.J....Wank S.A. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10203	HGNC: 16709	AceView: CALCRL	Ensembl:ENSG00000064989	euGenes: HUgn10203
ECgene: CALCRL	H-InvDB: CALCRL

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for CALCRL
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CALCRL:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CALCRL-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CALCRL		Antibodies for CALCRL
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CALCRL		Small molecules for CALCRL
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CALCRL)
	Antibodies (CALCRL)
	Chimera RNAi (CALCRL)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (CRLR)
	Antibodies (CRLR)

Search OriGene for CALCRL

Tocris compounds for CALCRL

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CALCRL

GeneCards Homepage - Last full update: 1 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
CALCRL Gene at Home site.
Version 2.41.1
server5.xennexinc.com

CALCRL Gene

protein-coding GIFtS: 60

Aliases &
Descriptions
for CALCRL

Summaries
for CALCRL

Genomic Location
for CALCRL

Proteins
for CALCRL

Protein Domains/
Families
for CALCRL

Gene Function
for CALCRL

Pathways & Interactions
for CALCRL

Drugs & Compounds
for CALCRL

Transcripts
for CALCRL

Expression
for CALCRL

Orthologs
for CALCRL

Paralogs
for CALCRL

SNPs/Variants
for CALCRL

Disorders & Mutations
for CALCRL

Medical News
for CALCRL

Publications
for CALCRL

Search for CALCRL

Genome Databases showing CALCRL

Other Databases showing CALCRL

Specialized Databases showing CALCRL

Licensable Technologies
for CALCRL

Services
for CALCRL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CALCRL Gene

protein-coding GIFtS: 60

Aliases & Descriptionsfor CALCRL

Summariesfor CALCRL

Genomic Locationfor CALCRL

Proteinsfor CALCRL

Protein Domains/Familiesfor CALCRL

Gene Functionfor CALCRL

Pathways & Interactionsfor CALCRL

Drugs & Compoundsfor CALCRL

Transcriptsfor CALCRL

Expression for CALCRL

Orthologsfor CALCRL

Paralogsfor CALCRL

SNPs/Variantsfor CALCRL

Disorders & Mutationsfor CALCRL

Medical Newsfor CALCRL

Publicationsfor CALCRL

Search for CALCRL

Genome Databases showing CALCRL

Other Databases showing CALCRL

Specialized Databases showing CALCRL

Licensable Technologiesfor CALCRL

Servicesfor CALCRL

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CALCRL

Summaries
for CALCRL

Genomic Location
for CALCRL

Proteins
for CALCRL

Protein Domains/
Families
for CALCRL

Gene Function
for CALCRL

Pathways & Interactions
for CALCRL

Drugs & Compounds
for CALCRL

Transcripts
for CALCRL

Expression
for CALCRL

Orthologs
for CALCRL

Paralogs
for CALCRL

SNPs/Variants
for CALCRL

Disorders & Mutations
for CALCRL

Medical News
for CALCRL

Publications
for CALCRL

Licensable Technologies
for CALCRL

Services
for CALCRL