CALCOCO2 Gene
protein-coding GIFtS: 52
GCID: GC17P046908
|
|
calcium binding and coiled-coil domain 2
| |
Aliases for CALCOCO2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Calcium Binding And Coiled-Coil Domain 21 2 | | Nuclear Domain 10 Protein NDP522 3 | | NDP521 2 3 | | Nuclear Dot Protein 522 3 | | Antigen Nuclear Dot 52 KDa Protein2 3 | | MGC173181 | | Nuclear Domain 10 Protein 522 3 | | Calcium-Binding And Coiled-Coil Domain-Containing Protein 22 |
Export aliases for CALCOCO2 gene to outside databasesPrevious GC identifers: GC17P044264 GC17P042276 |
Summaries for CALCOCO2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CALCOCO2: This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a receptor forubiquitin-coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternativelyspliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, May2012) UniProtKB/Swiss-Prot: CACO2_HUMAN, Q13137Function: May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulateconstitutive secretion Gene Wiki entry for CALCOCO2
|
Genomic Views for CALCOCO2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CALCOCO2 gene promoter: HFH-3 USF1 Sp1 GATA-3 USF2 USF-1:USF-2 GATA-2 GATA-1 FOXI1 USF-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for CALCOCO2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CALCOCO2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.32 Ensembl cytogenetic band: 17q21.32 HGNC cytogenetic band: 17q21.32CALCOCO2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P046908: view genomic region
(about GC identifiers)
Start:
|
46,908,350 bp from pter |
End:
|
46,943,884 bp from pter |
Size:
|
35,535 bases |
Orientation:
|
plus strand |
|
Proteins for CALCOCO2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CACO2_HUMAN, Q13137 (See
protein sequence)Recommended Name: Calcium-binding and coiled-coil domain-containing protein 2 Size: 446 amino acids; 52254 Da
Subunit: Part of a complex consisting of CALCOCO2, TAX1BP1 and MYO6. Interacts with GEMIN4
Subcellular location: Cytoplasm, perinuclear region. Golgi apparatus. Cytoplasm, cytoskeleton. Note=According toPubMed:7540613, localizes to nuclear dots. According to PubMed:9230084 and PubMed:12869526, it is not a nucleardot-associated protein but localizes predominantly in the cytoplasm with a coarse-grained distribution preferentiallyclose to the nucleus
Miscellaneous: According to PubMed:7540613, HSV-1 infection removes CALCOCO2 from the nucleus, however, it remainsfaintly in areas shown to be domains, containing splicing components. Treatment with IFNB1/IFN-beta and IFNG/IFN-gammashow an increase in number and size of CALCOCO2-specific dots and partial redistribution to the cytoplasm. Accordingto PubMed:9230084, IFNG/IFN-gamma increases gene expression only slightly and IFNB does not increase expression
Secondary accessions: B2RBT0 B4E0C0 E7ETP5 Q53FQ5 Q53HB5 Q6IBN9 Q9BTF7Alternative splicing: 2 isoforms: Q13137-1 Q13137-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CALCOCO2: NX_Q13137
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13137 CALCOCO2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001248319.1 NP_001248320.1 NP_001248322.1 NP_001248324.1 NP_005822.1 ENSEMBL proteins: ENSP00000258947 ENSP00000424352 ENSP00000398523 ENSP00000461083 ENSP00000425692 ENSP00000425090 ENSP00000406974 ENSP00000423437 ENSP00000461184 ENSP00000422697 ENSP00000424169 ENSP00000424889 ENSP00000424083 ENSP00000429963 Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
CALCOCO2 for ontologies About GeneDecksing
CALCOCO2 Antibody Products: Assay Products for CALCOCO2: |
Protein
Domains / Families for CALCOCO2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CALCOCO2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q13137ProtoNet protein and cluster: Q13137 1 Blocks protein family: IPB012852 Coiled-coil transcriptional coactivator-like
|
Function for CALCOCO2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CACO2_HUMAN, Q13137Function: May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulateconstitutive secretion
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CALCOCO2 (NM_005831) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CALCOCO2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CALCOCO2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CALCOCO2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CALCOCO2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for CALCOCO2:
|
Pathways & Interactions for CALCOCO2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and Autophagy | | | 2 | NF-kappaB Signaling | |
Pathway sources See GeneCards unified pathways Show all pathways
2
Cell Signaling Technology (CST) Pathways for CALCOCO2
CALCOCO2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CALCOCO2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/117 Interacting proteins for CALCOCO2 (Q131371, 2, 3 ENSP000002589474) via UniProtKB, MINT, STRING, and/or I2D (see all 117)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ABLIM1 | O146392, 3, ENSP000003381904 | MINT-67707 I2D:
score=5 STRING: ENSP00000338190 | | APEX2 | Q9UBZ42, 3, ENSP000003641264 | MINT-68260 I2D:
score=5 STRING: ENSP00000364126 | | C20orf195 | Q9BVV22, 3, ENSP000003591154 | MINT-67765 I2D:
score=5 STRING: ENSP00000359115 | | CPNE7 | Q9UBL62, 3, ENSP000002687204 | MINT-66571 I2D:
score=5 STRING: ENSP00000268720 | | FXR2 | P511162, 3, ENSP000002501134 | MINT-67257 I2D:
score=5 STRING: ENSP00000250113 | About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
CALCOCO2 for ontologies About GeneDecksing
|
Drugs & Compounds for CALCOCO2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CALCOCO2 Search CenterWatch for drugs/clinical trials and news about CALCOCO2 / CACO2 
|
Transcripts for CALCOCO2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CALCOCO2 gene (5 alternative transcripts): NM_001261390.1 NM_001261391.1 NM_001261393.1 NM_001261395.1 NM_005831.4 Unigene Cluster for CALCOCO2: Calcium binding and coiled-coil domain 2 Hs.514920 [show with all ESTs]Unigene Representative Sequence: NM_00126139018/28 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28): ENST00000258947(uc002iof.3 uc010wlp.2 uc010wlq.2 uc010wlr.2 uc010wls.2) ENST00000503463 ENST00000509507 ENST00000448105 ENST00000510356 ENST00000575560 ENST00000570513 ENST00000509415 ENST00000513119 ENST00000416445 ENST00000508679 ENST00000372317 ENST00000576582 ENST00000511697 ENST00000505071 ENST00000507076 ENST00000502761 ENST00000509014
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CALCOCO2 (NM_005831) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CALCOCO2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CALCOCO2  |
Additional cDNA sequence: AF085965.1 AK222666.1 AK223227.1 AK293137.1 AK293329.1 AK298177.1 AK303313.1 AK304024.1 AK310648.1 AK314796.1 BC004130.2 BC015893.2 CR456763.1 U22897.1 23 DOTS entries: DT.117717 DT.100016048 DT.95237406 DT.96085432 DT.97771081 DT.95237405 DT.206252 DT.99957369 DT.99986777 DT.92443486 DT.95113656 DT.97779365 DT.120949524 DT.120949531 DT.120949540 DT.92443482 DT.92443488 DT.95108827 DT.100828387 DT.91841599 DT.92443480 DT.95237415 DT.95175794 24/425 AceView cDNA sequences (see all 425): W37183 AA856598 AI263067 BM854998 AA553491 AW608180 AI568033 AI591389 AI566696 BM969054 AI263199 CB154237 AA854841 AU280407 AI283445 CA415014 BM981211 AU141952 NM_005831 AI439272 BX111525 BF794193 AI188175 BU165576 GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for CALCOCO2 (see all 11) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b | ^ | |
| SP1: | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | - |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   |
| ExUns: | 13 | ^ | 14a | · | 14b | ^ | 15 | |
| SP1: | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CALCOCO2
|
Expression for CALCOCO2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CALCOCO2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTAATTTCTC
About this image See CALCOCO2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CALCOCO2
SOURCE GeneReport for Unigene cluster: Hs.514920 UniProtKB/Swiss-Prot: CACO2_HUMAN, Q13137Tissue specificity: Expressed in all tissues tested with highest expression in skeletal muscle and lowest in brain SABiosciences Custom PCR Arrays for CALCOCO2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CALCOCO2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CALCOCO2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CALCOCO2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CALCOCO2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CALCOCO2 |
Orthologs for CALCOCO2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CALCOCO2 gene from 3/13 species (see all 13) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
CALCOCO21 |
calcium binding and coiled-coil domain 2 |
62.19(n) 51.94(a) |
  |
419993 XM_418115.3 XP_418115.2 |
lizard (Anolis carolinensis) |
Reptilia |
CALCOCO26 |
-- |
44(a) |
1 ↔ 1 |
6(75917254-75934026) |
zebrafish (Danio rerio) |
Actinopterygii |
calcoco21 |
calcium binding and coiled-coil domain 2 |
47.79(n) 33.33(a) |
  |
553776 NM_001020741.1 NP_001018577.1 |
ENSEMBL Gene Tree for CALCOCO2 (if available) TreeFam Gene Tree for CALCOCO2 (if available)  |
Paralogs for CALCOCO2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CALCOCO2 gene
- TAX1BP12 CALCOCO12
18/65 SIMAP similar genes for CALCOCO2 using alignment to 13 protein entries: CACO2_HUMAN (see all proteins)
(see all similar genes):C14orf105 DCAF17 IK RHBG SLC24A1 HDGFRP2 MTO1 ARL6IP5 DUSP3 HEXDC TAF2 FRG1 ZNF559 ASPSCR1 CSPP1 TUBA1C TMX3 C1orf143
CALCOCO2 for paralogs About GeneDecksing
|
Genomic Variants for CALCOCO2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CALCOCO2 (46908350 - 46943884 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for CALCOCO2 2 CNVs: 67216 0208  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CALCOCO2 |
|
Disorders
/ Diseases for CALCOCO2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CALCOCO2 for disorders About GeneDecksing
OMIM gene information: 604587
OMIM disorders: --
1 disease for CALCOCO2: About MalaCardsherpes simplex Export disorders for CALCOCO2 gene to outside databases
|
Publications for CALCOCO2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CALCOCO2 gene, integrated from 9 sources (see all 31): (articles sorted by number of sources associating them with CALCOCO2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular characterization of NDP52, a novel protein of the nuclear domain 10, which is redistributed upon virus infection and interferon treatment. (PubMed id 7540613)1, 2, 3 Korioth F.... Frey J. (1995)
- T6BP and NDP52 are myosin VI binding partners with potential roles in cytokine signalling and cell adhesion. (PubMed id 17635994)1, 2 Morriswood B.... Buss F. (2007)
- HCC-associated protein HCAP1, a variant of GEMIN4, interacts with zinc-finger proteins. (PubMed id 12869526)1, 2 Di Y.... Gu J. (2003)
- Cellular localization, expression, and structure of the nuclear dot protein 52. (PubMed id 9230084)1, 2 Sternsdorf T.... Will H. (1997)
- Selective autophagy degrades DICER and AGO2 and regula tes miRNA activity. (PubMed id 23143396)1 Gibbings D....Voinnet O. (2012)
- LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy. (PubMed id 23022382)1 von Muhlinen N....Randow F. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Regulation of Toll-like receptor signaling by NDP52-me diated selective autophagy is normally inactivated by A20. (PubMed id 21964925)1 Inomata M....Into T. (2012)
- Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for CALCOCO2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CALCOCO2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CALCOCO2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CALCOCO2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for CALCOCO2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CALCOCO2 gene: Search GeneIP for patents involving CALCOCO2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CALCOCO2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for CALCOCO2 | | OriGene shRNA RFP for CALCOCO2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CALCOCO2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CALCOCO2 | | OriGene Protein Over-expression Lysate for CALCOCO2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CALCOCO2 | | OriGene 3'-UTR Clone for CALCOCO2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CALCOCO2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for CALCOCO2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CALCOCO2 | | OriGene Custom Protein Services for CALCOCO2 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CALCOCO2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CALCOCO2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CALCOCO2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CALCOCO2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CALCOCO2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CALCOCO2 |
| |
 |  |  |  | |
| | | |  |  |  |  | | | | |
 |
 |
 |
 | | CALCOCO2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CALCOCO2 |
|  |  |  | | | Search ThermoFisher Antibodies for CALCOCO2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CALCOCO2 |
|
|
|
|