Aliases for CALB2 Gene
External Ids for CALB2 Gene
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
GeneCards Summary for CALB2 Gene
CALB2 (Calbindin 2) is a Protein Coding gene. Diseases associated with CALB2 include sex cord-gonadal stromal tumor and trisomy 22. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is SCGN.
UniProtKB/Swiss-Prot for CALB2 Gene
Calretinin is a calcium-binding protein which is abundant in auditory neurons