Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CAGE1 Gene

Aliases for CAGE1 Gene

  • Cancer Antigen 1 2 3
  • Cancer/Testis Antigen 3 2 3 4
  • Cancer/Testis Antigen 95 2 3
  • CTAG3 3 4
  • CT3 3 4
  • Cancer-Associated Gene 1 Protein 3
  • Cancer/Testis Antigen Gene 1 3
  • BA69L16.7 3
  • CTAG3, 6
  • CAGE-1 4
  • CT95 3

External Ids for CAGE1 Gene

Previous HGNC Symbols for CAGE1 Gene

  • CTAG3

Previous GeneCards Identifiers for CAGE1 Gene

  • GC06M007312
  • GC06M007273

Summaries for CAGE1 Gene

GeneCards Summary for CAGE1 Gene

CAGE1 (Cancer Antigen 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CAGE1 Gene

Genomics for CAGE1 Gene

Regulatory Elements for CAGE1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CAGE1 Gene

Start:
7,326,654 bp from pter
End:
7,389,743 bp from pter
Size:
63,090 bases
Orientation:
Minus strand

Genomic View for CAGE1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CAGE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CAGE1 Gene

Proteins for CAGE1 Gene

  • Protein details for CAGE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TC20-CAGE1_HUMAN
    Recommended name:
    Cancer-associated gene 1 protein
    Protein Accession:
    Q8TC20
    Secondary Accessions:
    • D6RCT9
    • Q5TAM0
    • Q86TM4
    • Q8N7R5

    Protein attributes for CAGE1 Gene

    Size:
    777 amino acids
    Molecular mass:
    90250 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI16451.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for CAGE1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CAGE1 Gene

Proteomics data for CAGE1 Gene at MOPED

Post-translational modifications for CAGE1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CAGE1 Gene

Domains for CAGE1 Gene

Protein Domains for CAGE1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CAGE1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CAGE1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CAGE1 Gene

Function for CAGE1 Gene

Gene Ontology (GO) - Molecular Function for CAGE1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CAGE1: view

Animal Model Products

miRNA for CAGE1 Gene

miRTarBase miRNAs that target CAGE1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CAGE1 Gene

Localization for CAGE1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CAGE1 Gene COMPARTMENTS Subcellular localization image for CAGE1 gene
Compartment Confidence
cytosol 3
nucleus 3
golgi apparatus 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CAGE1 Gene

Pathways for CAGE1 Gene

SuperPathways for CAGE1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CAGE1 Gene

None

No data available for Pathways by source for CAGE1 Gene

Transcripts for CAGE1 Gene

mRNA/cDNA for CAGE1 Gene

Unigene Clusters for CAGE1 Gene

Cancer antigen 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CAGE1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CAGE1 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c
SP1: - - -
SP2: -
SP3: - -
SP4: - - - - - -

Relevant External Links for CAGE1 Gene

GeneLoc Exon Structure for
CAGE1
ECgene alternative splicing isoforms for
CAGE1

Expression for CAGE1 Gene

mRNA expression in normal human tissues for CAGE1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CAGE1 Gene

This gene is overexpressed in Testis (49.4).

Protein differential expression in normal tissues for CAGE1 Gene

This gene is overexpressed in Islet of Langerhans (43.6) and Urine (25.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CAGE1 Gene

SOURCE GeneReport for Unigene cluster for CAGE1 Gene Hs.721486

mRNA Expression by UniProt/SwissProt for CAGE1 Gene

Q8TC20-CAGE1_HUMAN
Tissue specificity: Testis-specific expression in normal tissues, but wide expression among cancer tissues and cell lines
genes like me logo Genes that share expressions with CAGE1: view

Expression partners for CAGE1 Gene

In Situ Assay Products

Orthologs for CAGE1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CAGE1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CAGE1 35
  • 80.26 (n)
  • 66.23 (a)
CAGE1 36
  • 62 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CAGE1 35
  • 77.2 (n)
  • 64.04 (a)
CAGE1 36
  • 56 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cage1 35
  • 73.15 (n)
  • 60.35 (a)
Cage1 16
Cage1 36
  • 57 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CAGE1 35
  • 99.44 (n)
  • 99.05 (a)
CAGE1 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cage1 35
  • 72.5 (n)
  • 58.56 (a)
oppossum
(Monodelphis domestica)
Mammalia CAGE1 36
  • 45 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CAGE1 36
  • 39 (a)
OneToOne
Species with no ortholog for CAGE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CAGE1 Gene

ENSEMBL:
Gene Tree for CAGE1 (if available)
TreeFam:
Gene Tree for CAGE1 (if available)

Paralogs for CAGE1 Gene

No data available for Paralogs for CAGE1 Gene

Variants for CAGE1 Gene

Sequence variations from dbSNP and Humsavar for CAGE1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs754699 -- 7,361,499(-) ACTTA(C/T)ATGCA intron-variant
rs879294 -- 7,341,603(+) GTCCA(C/T)AGCAA intron-variant
rs942664 -- 7,328,920(-) ATATA(C/T)ACACA intron-variant, downstream-variant-500B
rs1324502 -- 7,368,684(-) AGGTA(C/T)TATAT intron-variant
rs1325030 -- 7,332,612(-) AAAAG(C/T)TGGGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CAGE1 Gene

Variant ID Type Subtype PubMed ID
nsv462623 CNV Gain 19166990
nsv470797 CNV Gain 18288195
nsv883433 CNV Gain 21882294

Relevant External Links for CAGE1 Gene

HapMap Linkage Disequilibrium report
CAGE1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CAGE1 Gene

Disorders for CAGE1 Gene

No disorders were found for CAGE1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CAGE1 Gene

Publications for CAGE1 Gene

  1. Identification and characterization of a novel cancer/testis antigen gene CAGE-1. (PMID: 12531476) Park S. … Jeoung D.I. (Biochim. Biophys. Acta 2003) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas. (PMID: 16964403) Kunze E. … Schlott T. (Int. J. Mol. Med. 2006) 3

Products for CAGE1 Gene

Sources for CAGE1 Gene

Back to Top

Content