Aliases for CACYBP Gene
External Ids for CACYBP Gene
Previous GeneCards Identifiers for CACYBP Gene
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CACYBP Gene
CACYBP (Calcyclin Binding Protein) is a Protein Coding gene. Diseases associated with CACYBP include gastric cancer and neuroblastoma. Among its related pathways are Wnt / Hedgehog / Notch and Wnt signaling pathway (KEGG). GO annotations related to this gene include protein homodimerization activity.
UniProtKB/Swiss-Prot for CACYBP Gene
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).