Aliases for CACNG6 Gene
External Ids for CACNG6 Gene
Previous GeneCards Identifiers for CACNG6 Gene
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010]
GeneCards Summary for CACNG6 Gene
CACNG6 (Calcium Channel, Voltage-Dependent, Gamma Subunit 6) is a Protein Coding gene. Diseases associated with CACNG6 include arrhythmogenic right ventricular cardiomyopathy and asthma. Among its related pathways are MAPK signaling pathway and ERK Signaling. GO annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is CACNG1.
UniProtKB/Swiss-Prot for CACNG6 Gene
Thought to stabilize the calcium channel in an inactivated (closed) state.