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CACNG5 Gene

protein-coding   GIFtS: 54
GCID: GC17P064873

Calcium Channel, Voltage-Dependent, Gamma Subunit 5

  See CACNG5-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Calcium Channel, Voltage-Dependent, Gamma Subunit 51 2
Neuronal Voltage-Gated Calcium Channel Gamma-5 Subunit2 3
Transmembrane AMPAR Regulatory Protein Gamma-52 3
TARP Gamma-52 3
Voltage-Dependent Calcium Channel Gamma-5 Subunit2

External Ids:    HGNC: 14091   Entrez Gene: 270912   Ensembl: ENSG000000754297   OMIM: 6064055   UniProtKB: Q9UF023   

Export aliases for CACNG5 gene to outside databases

Previous GC identifers: GC17M063533 GC17M066599 GC17P065290 GC17P065423 GC17P062303 GC17P060262


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CACNG5 Gene:
The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs
regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse
eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members,
a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and
bipolar disorder. (provided by RefSeq, Dec 2010)

GeneCards Summary for CACNG5 Gene:
CACNG5 (calcium channel, voltage-dependent, gamma subunit 5) is a protein-coding gene. Diseases associated with CACNG5 include bipolar disorder, and schizophrenia. GO annotations related to this gene include voltage-gated calcium channel activity and ion transmembrane transporter activity. An important paralog of this gene is CACNG4.

UniProtKB/Swiss-Prot: CCG5_HUMAN, Q9UF02
Function: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating
properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific
AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize
the calcium channel in an inactivated (closed) state (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CACNG5 gene promoter:
         C/EBPbeta   Brachyury   Lmo2   IRF-1   Cdc5   RORalpha2   Evi-1   S8   ZIC2/Zic2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCACNG5 promoter sequence
   Search Chromatin IP Primers for CACNG5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CACNG5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24   Ensembl cytogenetic band:  17q24.2   HGNC cytogenetic band: 17q24

CACNG5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CACNG5 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P064873:  view genomic region     (about GC identifiers)

Start:
64,831,235 bp from pter      End:
64,881,603 bp from pter
Size:
50,369 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CCG5_HUMAN, Q9UF02 (See protein sequence)
Recommended Name: Voltage-dependent calcium channel gamma-5 subunit  
Size: 275 amino acids; 30903 Da
Subunit: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as
an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2,
GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG7 and CACNG8. Interacts with GRIA1, GRIA2, GRIA3 and
GRIA4 (By similarity)
Secondary accessions: A8K2A6 Q547R3 Q8WXS7 Q9UHM3

Explore the universe of human proteins at neXtProt for CACNG5: NX_Q9UF02

Explore proteomics data for CACNG5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CACNG5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_665810.1  
    ENSEMBL proteins: 
     ENSP00000436836   ENSP00000303092   ENSP00000169565  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CACN: Calcium channel subunits

    3 InterPro protein domains:
     IPR008368 VDCC_gsu
     IPR004031 PMP22/EMP/MP20/Claudin
     IPR008369 VDCC_g5su

    Graphical View of Domain Structure for InterPro Entry Q9UF02

    ProtoNet protein and cluster: Q9UF02

    1 Blocks protein domain: IPB008369 Voltage-dependent calcium channel gamma-5 subunit signature

    UniProtKB/Swiss-Prot: CCG5_HUMAN, Q9UF02
    Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily


    Find genes that share domains with CACNG5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCG5_HUMAN, Q9UF02
    Function: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating
    properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific
    AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize
    the calcium channel in an inactivated (closed) state (By similarity)

         Genatlas biochemistry entry for CACNG5:
    calcium channel,voltage-dependent,gamma subunit 5

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005245voltage-gated calcium channel activity TAS10613843
    GO:0005515protein binding ----
    GO:0015075ion transmembrane transporter activity TAS10613843
         
    Find genes that share ontologies with CACNG5           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CACNG5
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CACNG5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CACNG5

    miRNA
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    miRTarBase miRNAs that target CACNG5:
    hsa-mir-7-5p (MIRT025910)

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    Search for qRT-PCR Assays for microRNAs that regulate CACNG5
    SwitchGear 3'UTR luciferase reporter plasmidCACNG5 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CCG5_HUMAN, Q9UF02: Membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic
    cell membrane, postsynaptic density (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    plasma membrane4
    extracellular2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0014069postsynaptic density ISS--
    GO:0016021integral component of membrane ----
    GO:0030054cell junction IEA--
    GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex ISS--
    GO:0045211postsynaptic membrane IEA--

    Find genes that share ontologies with CACNG5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CACNG5 About   (see all 22)  
    See pathways by source

    SuperPathContained pathways About
    1Hypertrophic cardiomyopathy (HCM)
    Hypertrophic cardiomyopathy (HCM)0.75
    Arrhythmogenic right ventricular cardiomyopathy (ARVC)0.54
    Dilated cardiomyopathy0.75
    Arrhythmogenic right ventricular cardiomyopathy0.54
    2TCR Signaling (Qiagen)
    PKC-Theta Pathway0.68
    Fc-EpsilonRI Pathway0.49
    TCR Signaling0.68
    PDGF Pathway0.39
    ITK and TCR Signaling0.54
    3DREAM Repression and Dynorphin Expression
    DREAM Repression and Dynorphin Expression0.44
    Caspase Cascade0.36
    BMP Pathway0.44
    Calpain Protease Regulates Cellular Mechanics0.31
    nNOS Signaling in Skeletal Muscle0.37
    4Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Cellular Effects of Sildenafil0.46
    Melatonin Signaling0.72
    5Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    PKA Signaling0.56
    cAMP Pathway0.77


    Find genes that share SuperPaths with CACNG5           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for CACNG5 (see all 37)
        Caspase Cascade
    Fc-GammaR Pathway
    Intracellular Calcium Signaling
    PDGF Pathway
    BMP Pathway

    1 GeneGo (Thomson Reuters) Pathway for CACNG5
        Transcription CREB pathway

    1 BioSystems Pathway for CACNG5
        Arrhythmogenic right ventricular cardiomyopathy


    Selected Kegg Pathways  (Kegg details for CACNG5) (see all 7):
        MAPK signaling pathway
    Cardiac muscle contraction
    Adrenergic signaling in cardiomyocytes
    Oxytocin signaling pathway
    Hypertrophic cardiomyopathy (HCM)

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CACNG5
    Interactions:

        Search GeneGlobe Interaction Network for CACNG5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CACNG5 (ENSP000001695654) via UniProtKB, MINT, STRING, and/or I2D (see all 36)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKACAENSP000003095914STRING: ENSP00000309591
    PRKACBENSP000003597194STRING: ENSP00000359719
    PRKACGENSP000003664884STRING: ENSP00000366488
    PRKXENSP000002628484STRING: ENSP00000262848
    RASGRF1ENSP000004059634STRING: ENSP00000405963
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport TAS10613843
    GO:2000311regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ISS--

    Find genes that share ontologies with CACNG5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CACNG5 (CCG5)

    1 HMDB Compound for CACNG5    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CACNG5 gene (2 alternative transcripts): 
    NM_145811.2  NM_014404.1  

    Unigene Cluster for CACNG5:

    Calcium channel, voltage-dependent, gamma subunit 5
    Hs.278907  [show with all ESTs]
    Unigene Representative Sequence: AK290171
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000533854(uc010wqi.2 uc010wqj.2) ENST00000307139 ENST00000169565

    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat CACNG5

    Additional mRNA sequence: 

    AF361351.1 AF458898.1 AK290171.1 BC101607.1 BC101633.1 

    2 DOTS entries:

    DT.97824194  DT.75104055 

    5 AceView cDNA sequences:

    NM_014404 NM_145811 AF458898 AF148220 AF361351 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CACNG5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TACAGGCCCC
    CACNG5 Expression
    About this image


    CACNG5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Hyoid Arch Muscles
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
    CACNG5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CACNG5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.278907
        Custom PCR Arrays for CACNG5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CACNG5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CACNG5 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cacng51 , 5 calcium channel, voltage-dependent, gamma subunit 51, 5 89.45(n)1
    97.09(a)1
      11 (70.44 cM)5
    1407231  NM_001199301.11  NP_001186230.11 
     1078746055 
    chicken
    (Gallus gallus)
    Aves LOC1008596141 voltage-dependent calcium channel gamma-5 subunit-like 83.15(n)
    93.82(a)
      100859614  XM_003642343.2  XP_003642391.2 
    lizard
    (Anolis carolinensis)
    Reptilia CACNG56
    calcium channel, voltage-dependent, gamma subunit ...
    83(a)
    1 ↔ 1
    GL343250.1(37503-73260)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003311161 voltage-dependent calcium channel gamma-5 subunit-like 80.48(n)
    90.18(a)
      100331116  XM_002661274.2  XP_002661320.1 


    ENSEMBL Gene Tree for CACNG5 (if available)
    TreeFam Gene Tree for CACNG5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CACNG5 gene
    CACNG42  CACNG72  CACNG22  CACNG82  CACNG32  
    3 SIMAP similar genes for CACNG5 using alignment to 1 protein entry:     CCG5_HUMAN:
    CACNG7    CACNG4    CACNG8

    Find genes that share paralogs with CACNG5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CACNG5 (see all 276)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1147724491,2
    F--64871431(+) TTTCAT/CTTCTC 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1914289601,2
    --64871543(+) AGCCAA/GTATAT 1 -- us2k10--------
    rs1507727361,2
    --64871625(+) GCCAGC/TGTGCA 1 -- us2k10--------
    rs1154728311,2
    F--64871677(+) CTCTCC/TTCCTA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs37602651,2
    C,F,A,H--64871721(-) AAATGG/AACAGA 1 -- us2k126Minor allele frequency- A:0.32EA NS NA WA CSA 3961
    rs1146439561,2
    F--64871863(+) CCCAAA/GCATCA 1 -- us2k11Minor allele frequency- G:0.03WA 118
    rs728433661,2
    C,F--64871868(+) ACATCA/GCTAAC 1 -- us2k12Minor allele frequency- G:0.08WA NA 238
    rs98900011,2
    C,F--64871902(+) TTGCAA/GTATTG 1 -- us2k12Minor allele frequency- G:0.05WA 120
    rs1843286291,2
    --64871906(+) AATATA/TGCAAG 1 -- us2k10--------
    rs1897408891,2
    --64871930(+) ATGCCA/GACAGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CACNG5 (64831235 - 64881603 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CACNG5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833521CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CACNG5
    DNA2.0 Custom Variant and Variant Library Synthesis for CACNG5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606405    OMIM disorders: --

    2 diseases for CACNG5:    
    About MalaCards
    bipolar disorder    schizophrenia


    Find genes that share disorders with CACNG5           About GenesLikeMe

    Genetic Association Database (GAD): CACNG5
    Human Genome Epidemiology (HuGE) Navigator: CACNG5 (1 document)

    Export disorders for CACNG5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CACNG5 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CACNG5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. (PubMed id 10613843)1, 2, 3 Burgess D.L.... Noebels J.L. (Genome Res. 1999)
    2. Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes. (PubMed id 21057379)1, 4 Curtis D....Gurling H.M. (Psychiatr. Genet. 2011)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The novel product of a five-exon stargazin-related gene abolishes CaV2.2 calcium channel expression. (PubMed id 11927536)1, 2 Moss F.J.... Dolphin A.C. (EMBO J. 2002)
    5. Calcium channel gamma subunits provide insights into the evolution of this gene family. (PubMed id 11738816)1, 2 Chu P.-J.... Best P.M. (Gene 2001)
    6. Calcium channel gamma subunits: a functionally diverse protein family. (PubMed id 17652770)1 Chen R.S....Best P.M. (Cell Biochem. Biophys. 2007)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. (PubMed id 11170751)1 Burgess D.L.... Noebels J.L. (Genomics 2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27091 HGNC: 1409 AceView: CACNG5 Ensembl:ENSG00000075429 euGenes: HUgn27091
    ECgene: CACNG5 Kegg: 27091 H-InvDB: CACNG5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CACNG5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CACNG5 gene:
    Search GeneIP for patents involving CACNG5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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