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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CACNG3 Gene

protein-coding   GIFtS: 61
GCID: GC16P024267

Calcium Channel, Voltage-Dependent, Gamma Subunit 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Calcium Channel, Voltage-Dependent, Gamma Subunit 31 2
Neuronal Voltage-Gated Calcium Channel Gamma-3 Subunit2 3
Transmembrane AMPAR Regulatory Protein Gamma-32 3
TARP Gamma-32 3
Voltage-Dependent Calcium Channel Gamma-3 Subunit2
Voltage-Gated Calcium Channel Gamma Subunit2

External Ids:    HGNC: 14071   Entrez Gene: 103682   Ensembl: ENSG000000061167   OMIM: 6064035   UniProtKB: O603593   

Export aliases for CACNG3 gene to outside databases

Previous GC identifers: GC16P023676 GC16P024366 GC16P024194 GC16P024233 GC16P024174 GC16P022358


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CACNG3 Gene:
The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate
both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse
eight-member protein subfamily of the PMP-22/EMP/MP20 family. This gene is a susceptibility locus for childhood
absence epilepsy. (provided by RefSeq, Dec 2010)

GeneCards Summary for CACNG3 Gene: 
CACNG3 (calcium channel, voltage-dependent, gamma subunit 3) is a protein-coding gene. Diseases associated with CACNG3 include childhood absence epilepsy, and juvenile absence epilepsy, and among its related super-pathways are Hypertrophic cardiomyopathy (HCM) and PKC-Theta Pathway. GO annotations related to this gene include voltage-gated calcium channel activity. An important paralog of this gene is CACNG4.

UniProtKB/Swiss-Prot: CCG3_HUMAN, O60359
Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes
their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of
activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and
regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By
similarity)

Gene Wiki entry for CACNG3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010393.16  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CACNG3 gene promoter:
         TBP   LHX3b/Lhx3b   NRSF form 1   MyoD   Nkx2-5   LCR-F1   Tal-1beta   NRSF form 2   E47   LHX3a/Lhx3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCACNG3 promoter sequence
   Search SABiosciences Chromatin IP Primers for CACNG3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CACNG3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.1   Ensembl cytogenetic band:  16p12.1   HGNC cytogenetic band: 16p12.1

CACNG3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CACNG3 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P024267:  view genomic region     (about GC identifiers)

Start:
24,266,874 bp from pter      End:
24,374,122 bp from pter
Size:
107,249 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CCG3_HUMAN, O60359 (See protein sequence)
Recommended Name: Voltage-dependent calcium channel gamma-3 subunit  
Size: 315 amino acids; 35549 Da
Subunit: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as
an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2,
GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein

Explore the universe of human proteins at neXtProt for CACNG3: NX_O60359

Explore proteomics data for CACNG3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O60359

  • CACNG3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CACNG3 Protein Expression
    REFSEQ proteins: NP_006530.1  
    ENSEMBL proteins: 
     ENSP00000005284  
    Reactome Protein details: O60359
    Human Recombinant Protein Products for CACNG3: 
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    Novus Biologicals CACNG3 Protein
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005891voltage-gated calcium channel complex NAS10221464
    GO:0016021integral to membrane ----
    GO:0030666endocytic vesicle membrane TAS--
    GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex ISS--

    CACNG3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CACN: Calcium channel subunits

    2 InterPro protein domains:
     IPR008368 VDCC_gsu
     IPR004031 PMP22/EMP/MP20/Claudin

    Graphical View of Domain Structure for InterPro Entry O60359

    ProtoNet protein and cluster: O60359

    1 Blocks protein domain: IPB006187 Claudin family signature

    UniProtKB/Swiss-Prot: CCG3_HUMAN, O60359
    Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily


    CACNG3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CCG3_HUMAN, O60359
    Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes
    their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of
    activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and
    regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By
    similarity)

         Genatlas biochemistry entry for CACNG3:
    calcium voltage-gated channel (VDCC),L type,dihydropyridine (DPH) sensitive,gamma regulatory subunit 3,neuronal

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005245voltage-gated calcium channel activity NAS10221464
         
    CACNG3 for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cacng3):
     behavior/neurological  growth/size  homeostasis/metabolism  mortality/aging  nervous system 
     normal 

    CACNG3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cacng3tm1Ran for CACNG3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CACNG3 
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    SwitchGear 3'UTR luciferase reporter plasmidCACNG3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CACNG3 About   (see all 22)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Hypertrophic cardiomyopathy (HCM)
    Hypertrophic cardiomyopathy (HCM)0.75
    Arrhythmogenic right ventricular cardiomyopathy (ARVC)0.54
    Dilated cardiomyopathy0.75
    Arrhythmogenic right ventricular cardiomyopathy0.53
    2PKC-Theta Pathway
    TCR Signaling0.68
    Fc-EpsilonRI Pathway0.49
    PKC-Theta Pathway0.68
    PDGF Pathway0.39
    ITK and TCR Signaling0.54
    3DREAM Repression and Dynorphin Expression
    DREAM Repression and Dynorphin Expression0.44
    Caspase Cascade0.36
    BMP Pathway0.44
    Calpain Protease Regulates Cellular Mechanics0.31
    nNOS Signaling in Skeletal Muscle0.37
    4Transmission across Chemical Synapses
    Transmission across Chemical Synapses0.72
    Neuronal System0.67
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell0.72
    5Sweet Taste Signaling
    Sweet Taste Signaling0.72
    Cellular Effects of Sildenafil0.46
    Melatonin Signaling0.72

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for CACNG3
        Transcription CREB pathway

    5/37 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CACNG3 (see all 37)
        Caspase Cascade
    Fc-GammaR Pathway
    Intracellular Calcium Signaling
    PDGF Pathway
    BMP Pathway

    1 GeneGo (Thomson Reuters) Pathway for CACNG3
        Transcription CREB pathway

    1 BioSystems Pathway for CACNG3
        Arrhythmogenic right ventricular cardiomyopathy


    5        Reactome Pathways for CACNG3
        Trafficking of AMPA receptors
    Transmission across Chemical Synapses
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
    Neuronal System
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell


    5         Kegg Pathways  (Kegg details for CACNG3):
        MAPK signaling pathway
    Cardiac muscle contraction
    Hypertrophic cardiomyopathy (HCM)
    Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    Dilated cardiomyopathy


    CACNG3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CACNG3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/74 Interacting proteins for CACNG3 (O603593 ENSP000000052844) via UniProtKB, MINT, STRING, and/or I2D (see all 74)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AP4M1O001893, ENSP000003526034I2D: score=1 STRING: ENSP00000352603
    CACNA1DENSP000002881394STRING: ENSP00000288139
    CACNA1FENSP000003654414STRING: ENSP00000365441
    CACNA2D1ENSP000003493204STRING: ENSP00000349320
    CACNB3ENSP000003010504STRING: ENSP00000301050
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006816calcium ion transport NAS10221464
    GO:0007268synaptic transmission TAS--
    GO:2000311regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity ISS--

    CACNG3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CACNG3 (CCG3)

    1 HMDB Compound for CACNG3    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about CACNG3 / CCG3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CACNG3 gene: 
    NM_006539.3  

    Unigene Cluster for CACNG3:

    Calcium channel, voltage-dependent, gamma subunit 3
    Hs.7235  [show with all ESTs]
    Unigene Representative Sequence: AK095553
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000005284(uc002dmf.3)
    miRNA
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    Additional mRNA sequence: 

    AF100346.1 AF114832.1 AF134640.1 AK055453.1 AK095553.1 AK315150.1 BC033741.1 BC037899.1 
    BC040005.1 

    2 DOTS entries:

    DT.310823  DT.101982910 

    24/54 AceView cDNA sequences (see all 54):

    AK055453 CR623650 BP346488 NM_006539 CB153595 AF114832 BX464317 BM672265 
    AF100346 BC037899 AK095553 BC033741 BC040005 BX280569 AF134640 BI821441 
    BP350289 BQ186344 BX422744 T23680 BG705097 BI546513 BI754521 BX091682 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CACNG3 expression in normal human tissues (normalized intensities)      CACNG3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATTAAAGG
    CACNG3 Expression
    About this image


    CACNG3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 18 entries
             Thalamus
             Septum   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Dorsal Horn   
     
     Eye (Sensory Organs)
             Mature Horizontal Cells Inner Nuclear Layer

    See CACNG3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CACNG3

    SOURCE GeneReport for Unigene cluster: Hs.7235
        SABiosciences Custom PCR Arrays for CACNG3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CACNG3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CACNG3 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cacng31 , 5 calcium channel, voltage-dependent, gamma subunit 31, 5 90.58(n)1
    98.73(a)1
      7 (66.81 cM)5
    543761  NM_019430.21  NP_062303.21 
     1226704925 
    chicken
    (Gallus gallus)
    Aves CACNG31 calcium channel, voltage-dependent, gamma subunit 3 79.72(n)
    89.81(a)
      395378  NM_204660.1  NP_989991.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5648831 voltage-dependent calcium channel gamma-3 subunit-like 73.27(n)
    82.14(a)
      564883  XM_688207.3  XP_693299.1 


    ENSEMBL Gene Tree for CACNG3 (if available)
    TreeFam Gene Tree for CACNG3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CACNG3 gene
    CACNG42  CACNG72  CACNG52  CACNG22  CACNG82  
    3 SIMAP similar genes for CACNG3 using alignment to 1 protein entry:     CCG3_HUMAN:
    CACNG2    CACNG4    CACNG8

    CACNG3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2417 SNPs in CACNG3 are shown (see all 2417)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1855969621,2
    --24264981(+) ACCTTA/CATCTA 1 -- us2k10--------
    rs1424384031,2
    --24265007(+) CTTTTA/CCCCCA 1 -- us2k10--------
    rs1509366461,2
    C--24265073(+) GTAGAA/GCTAAG 1 -- us2k10--------
    rs1496945931,2
    --24265156(+) AGCCCA/GAAGCT 1 -- us2k10--------
    rs1467063131,2
    C--24265215(+) ACTTCA/TATCCA 1 -- us2k10--------
    rs1905126961,2
    --24265222(+) TCCAAA/GCAAGA 1 -- us2k10--------
    rs1932660011,2
    C--24265251(+) TGAAAC/TGACTG 1 -- us2k10--------
    rs1842327441,2
    --24265321(+) TTTGCC/TAACTG 1 -- us2k10--------
    rs37601051,2
    C,F,H--24265411(-) TCCTGC/TCTTGA 1 -- us2k131Minor allele frequency- T:0.24EA NA NS CSA WA 4618
    rs1889410521,2
    --24265543(+) GCTGGC/GCCCAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CACNG3 (24266874 - 24374122 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for CACNG3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2714112CNV Deletion23290073
    esv2714113CNV Deletion23290073
    esv1634914CNV Deletion17803354
    esv2714111CNV Deletion23290073
    esv2714110CNV Deletion23290073
    esv272515CNV Insertion20981092
    esv271292CNV Insertion20981092
    esv34056CNV Loss18971310
    nsv833174CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606403    OMIM disorders: --

    8 diseases for CACNG3:    About MalaCards
    childhood absence epilepsy    juvenile absence epilepsy    idiopathic generalized epilepsy    age related macular degeneration
    macular degeneration    neuronitis    hypertrophic cardiomyopathy    dilated cardiomyopathy

    2 diseases from the University of Copenhagen DISEASES database for CACNG3:
    Juvenile absence epilepsy     Idiopathic generalized epilepsy

    CACNG3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CACNG3
    Human Genome Epidemiology (HuGE) Navigator: CACNG3 (2 documents)

    Export disorders for CACNG3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CACNG3 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with CACNG3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cloning of putative human neuronal voltage-gated calcium channel gamma-2 and gamma-3 subunits: neurologic implications. (PubMed id 10221464)1, 2, 3, 9 Black J.L. III and Lennon V.A. (1999)
    2. Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PubMed id 10493829)1, 2, 3 Loftus B.J.... Adams M.D. (1999)
    3. Linkage and association analysis of CACNG3 in childhood absence epilepsy. (PubMed id 17264864)1, 4 Everett K.V....Gardiner M. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Dissection of chromosome 16p12 linkage peak suggests a possible role for CACNG3 variants in age-related macular degeneration suscept ibility. (PubMed id 21169531)1 Spencer K.L....Haines J.L. (2011)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. TARPs differentially decorate AMPA receptors to speci fy neuropharmacology. (PubMed id 20219255)1 Kato A.S....Bredt D.S. (2010)
    8. Functional modulation of AMPA receptors by transmembrane AMPA receptor regulatory proteins. (PubMed id 18304745)1 Sager C....Hollmann M. (2009)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Calcium channel gamma subunits: a functionally divers e protein family. (PubMed id 17652770)1 Chen R.S....Best P.M. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10368 HGNC: 1407 AceView: CACNG3 Ensembl:ENSG00000006116 euGenes: HUgn10368
    ECgene: CACNG3 Kegg: 10368 H-InvDB: CACNG3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CACNG3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CACNG3 gene:
    Search GeneIP for patents involving CACNG3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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