Aliases for CACNB3 Gene
External Ids for CACNB3 Gene
Previous HGNC Symbols for CACNB3 Gene
Previous GeneCards Identifiers for CACNB3 Gene
This gene encodes a regulatory beta subunit of the voltage-dependent calcium channel. Beta subunits are composed of five domains, which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport. [provided by RefSeq, Oct 2011]
GeneCards Summary for CACNB3 Gene
CACNB3 (Calcium Voltage-Gated Channel Auxiliary Subunit Beta 3) is a Protein Coding gene. Among its related pathways are NFAT and Cardiac Hypertrophy and Myometrial Relaxation and Contraction Pathways. GO annotations related to this gene include protein kinase binding and high voltage-gated calcium channel activity. An important paralog of this gene is CACNB4.
UniProtKB/Swiss-Prot for CACNB3 Gene
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.