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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CACHD1 Gene

protein-coding GIFtS: 49
GCID: GC01P064936

cache domain containing 1

(Previous name: von Willebrand factor type A and cache domain containing...)
(Previous symbol: VWCD1)

Search for CACHD1
in

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our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Cache Domain Containing 1¹ ²		Cache Domain-Containing Protein 1² ³
Von Willebrand Factor Type A And Cache Domain Containing 1¹ ²		RP4-655E10.1²
KIAA1573¹ ³		VWFA And Cache Domain-Containing Protein 1²
VWCD1¹ ³

External Ids:	HGNC: 29314¹	Entrez Gene: 57685²	Ensembl: ENSG00000158966⁷	UniProtKB: Q5VU97³

Export aliases for CACHD1 gene to outside databases

Previous GC identifers: GC01P064685 GC01P063045

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CAHD1_HUMAN, Q5VU97

Function: May regulate voltage-dependent calcium channels (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_032977.9

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CACHD1 gene promoter:
NF-1 Pax-2 Pax-2a Nkx2-5 C/EBPalpha GATA-2 MZF-1 S8
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CACHD1 promoter sequence

Search SABiosciences Chromatin IP Primers for CACHD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CACHD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p31.3 Ensembl cytogenetic band: 1p31.3 HGNC cytogenetic band: 1p31.3

CACHD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CACHD1 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P064936: view genomic region (about GC identifiers)

Start:	64,936,428 bp from pter	End:	65,158,741 bp from pter
Size:	222,314 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CAHD1_HUMAN, Q5VU97 (See protein sequence)

Recommended Name: VWFA and cache domain-containing protein 1 precursor

Size: 1274 amino acids; 142290 Da

Subcellular location: Membrane; Single-pass type I membrane protein (Potential)

Sequence caution: Sequence=BAB14105.1; Type=Erroneous initiation; Sequence=BAB14860.1; Type=Erroneous initiation;

Sequence=CAH70309.1; Type=Erroneous initiation; Sequence=CAI22137.1; Type=Erroneous initiation;

Secondary accessions: Q49AE9 Q658T4 Q7Z3P2 Q9H7W4 Q9H9W3 Q9HCJ9

Alternative splicing: 2 isoforms: Q5VU97-1 Q5VU97-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CACHD1: NX_Q5VU97

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5VU97

CACHD1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065976.2

ENSEMBL proteins:

ENSP00000290039 ENSP00000360113

Human Recombinant Protein Products for CACHD1:

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	Uscn Proteins for CACHD1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

CACHD1 for ontologies About GeneDecksing

CACHD1 Antibody Products:

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	Novus Biologicals CACHD1 Antibodies
	Abcam antibodies for CACHD1
	Uscn Antibodies for CACHD1
	Search ThermoFisher Antibodies for CACHD1

Assay Products for CACHD1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for CACHD1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CACHD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CACHD1 for domains About GeneDecksing

3 InterPro domains/families:

IPR004010 Cache_domain

IPR013608 VWA_N

IPR002035 VWF_A

Graphical View of Domain Structure for InterPro Entry Q5VU97

ProtoNet protein and cluster: Q5VU97

1 Blocks protein family: IPB004010 Cache domain

UniProtKB/Swiss-Prot: CAHD1_HUMAN, Q5VU97

Similarity: Belongs to the calcium channel subunit alpha-2/delta family

Similarity: Contains 2 cache domains

Similarity: Contains 1 VWFA domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: CAHD1_HUMAN, Q5VU97

Function: May regulate voltage-dependent calcium channels (By similarity)

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CACHD1

miRNA Products:		OriGene 3'-UTR Clone: CACHD1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CACHD1
		8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate CACHD1 (see all 30):
		hsa-miR-30c hsa-miR-579 hsa-miR-429 hsa-miR-411 hsa-miR-30d hsa-miR-500a hsa-miR-144 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: CACHD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CACHD1 (see all 4) OriGene shRNA RFP: CACHD1 Browse OriGene siRNA
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		Sirion Biotech Custom design and validation of potent shRNA sequences against CACHD1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for CACHD1
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CACHD1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CACHD1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CACHD1 (NM_020925)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CACHD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CACHD1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CACHD1
		Search LifeMap BioReagents cell lines for CACHD1
		Sirion Biotech Customized stable knockdown cell line services for CACHD1 Sirion Biotech Customized inducible knockdown cell line services for CACHD1 Sirion Biotech Customized stable overexpressing cell line services for CACHD1 Sirion Biotech Customized inducible overexpressing cell line services for CACHD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CACHD1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CACHD1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/52 Interacting proteins for CACHD1 (Q5VU97^{2, 3} ENSP00000290039⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 52)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RANBP10	Q6VN20³, ENSP00000316589⁴	I2D: score=3 STRING: ENSP00000316589
XAB2	Q9HCS7³, ENSP00000351137⁴	I2D: score=3 STRING: ENSP00000351137
ZMIZ1	Q9ULJ6³, ENSP00000334474⁴	I2D: score=2 STRING: ENSP00000334474
GLTSCR1L	Q6AI39³, ENSP00000313933⁴	I2D: score=3 STRING: ENSP00000313933
PEBP1	P30086³, ENSP00000261313⁴	I2D: score=1 STRING: ENSP00000261313

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006816	calcium ion transport	IEA	--

CACHD1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CACHD1

1 HMDB Compound for CACHD1 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

Search CenterWatch for drugs/clinical trials and news about CACHD1 / CAHD1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CACHD1 gene:

NM_020925.2

Unigene Cluster for CACHD1:

Cache domain containing 1

Hs.443891 [show with all ESTs]

Unigene Representative Sequence: BX537603

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000290039(uc001dbo.1) ENST00000495994(uc001dbp.1) ENST00000470527(uc001dbq.1 uc010opa.1)

ENST00000486580 ENST00000371073

miRNA Products:		OriGene 3'-UTR Clone: CACHD1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CACHD1
		8/30 QIAGEN miScript miRNA Assays for microRNAs that regulate CACHD1 (see all 30):
		hsa-miR-30c hsa-miR-579 hsa-miR-429 hsa-miR-411 hsa-miR-30d hsa-miR-500a hsa-miR-144 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: CACHD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CACHD1 (see all 4) OriGene shRNA RFP: CACHD1 Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CACHD1
		Sirion Biotech Custom design and validation of potent shRNA sequences against CACHD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CACHD1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CACHD1 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CACHD1 (NM_020925)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CACHD1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CACHD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CACHD1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CACHD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CACHD1

Additional cDNA sequence:

AB046793.1 AK022571.1 AK024256.1 AK026777.1 AK126515.1 AK131297.1 AK299361.1 AL833000.1

BC039301.1 BX537603.1

7 DOTS entries:

DT.95264455 DT.111061 DT.100816081 DT.102826802 DT.97807869 DT.121391215 DT.121391247

24/110 AceView cDNA sequences (see all 110):

N79114 AK022571 AW292961 AU132649 AK126515 AI290002 AB046793 AA385638

AU131750 AU130699 AU132933 AL833000 BX101292 CB130379 AK024256 AI312901

BF724338 BU160602 BC039301 BG035210 AU124132 BU940193 AA598639 H48360

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for CACHD1 About this scheme

ExUns:	1	^	2	^	3a	·	3b	·	3c	·	3d	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14	^	15	^	16a	·	16b	^	17a	·	17b	^	18	^	19	^	20	^
SP1:																																							-
SP2:															-																								-
SP3:															-				-
SP4:
SP5:

ExUns:	21	^	22	^	23	^	24	^	25	^	26	^	27	^	28
SP1:
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for CACHD1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CACHD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTAAAGAATG

About this image

CACHD1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

5 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Adipose

Visceral White Adipose

Adipose

Brain

Cerebral Cortex

Brain

Neural Tube

Mesencephalic Ventricular Zone

Neural Tube

Metencephalon

Neural Tube

Telencephalon

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CACHD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CACHD1

SOURCE GeneReport for Unigene cluster: Hs.443891

SABiosciences Custom PCR Arrays for CACHD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CACHD1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CACHD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CACHD1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CACHD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CACHD1 gene from 5/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CACHD1¹	cache domain containing 1	82.64(n) 95.91(a)		424693 XM_422524.3 XP_422524.3
lizard (Anolis carolinensis)	Reptilia	CACHD1⁶	--	95(a)	1 ↔ 1	4(98572308-98669815)
African clawed frog (Xenopus laevis)	Amphibia	Xl.10935²	Xenopus laevis transcribed sequences	79.61(n)		CB206631.1
zebrafish (Danio rerio)	Actinopterygii	Dr.15338²	Transcribed sequences	81.7(n)		AL925090.1
fruit fly (Drosophila melanogaster)	Insecta	CG16868¹	CG16868	46.56(n) 34.42(a)		37298 NM_137625.1 NP_611469.1

ENSEMBL Gene Tree for CACHD1 (if available)
TreeFam Gene Tree for CACHD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CACHD1 gene

CACNA2D4² CACNA2D2² CACNA2D1² CACNA2D3²

CACHD1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs6656877^1,2	C	--	64934635(+)	`catggC/Tgaaac`	1	--	us2k¹		0	--	--	--	--
rs192865340^1,2		--	64934792(+)	`GCTGTA/GAAATG`	1	--	us2k¹		0	--	--	--	--
rs145692410^1,2		--	64934797(+)	`AAATG-/AAAAAG`	1	--	us2k¹		0	--	--	--	--
rs185023254^1,2		--	64934869(+)	`TTAACA/CTTCCA`	1	--	us2k¹		0	--	--	--	--
rs72673303^1,2	C	--	64934918(+)	`CACACA/GGGGCT`	1	--	us2k¹		0	--	--	--	--
rs115014911^1,2	F	--	64935034(+)	`GGAAGG/ATTAAC`	1	--	us2k¹		1		WA	118
rs146040943^1,2		--	64935114(+)	`TTTCTC/TGCTTT`	1	--	us2k¹		0	--	--	--	--
rs116205551^1,2	F	--	64935192(+)	`CCTTGG/CAGTAA`	1	--	us2k¹		1		WA	118
rs189434672^1,2		--	64935202(+)	`AGACTG/TGTGCT`	1	--	us2k¹		0	--	--	--	--
rs148688254^1,2		--	64935310(+)	`GATACA/GTACCT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for CACHD1 (64936428 - 65158741 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CACHD1
1 Indel: 44602
Human Gene Mutation Database (HGMD): CACHD1

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CACHD1

DNA2.0 Custom Variant and Variant Library Synthesis for CACHD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CACHD1 for disorders About MalaCards

CACHD1 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: CACHD1 (1 document)

Export disorders for CACHD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CACHD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CACHD1)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)^{1, 2, 3} Nagase T.... Ohara O. (2000)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Proteomic identification of common SCF ubiquitin ligas e FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)¹ Liu B....Wang L.S. (2012)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs. (PubMed id 12421765)¹ Nakayama M....Ohara O. (2002)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57685	HGNC: 29314	AceView: KIAA1573	Ensembl:ENSG00000158966	euGenes: HUgn57685
ECgene: CACHD1	H-InvDB: CACHD1

(According to HUGE)
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HUGE: KIAA1573

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CACHD1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CACHD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CACHD1 gene:
Search GeneIP for patents involving CACHD1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CACHD1

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CACHD1

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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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