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CABYR Gene

protein-coding   GIFtS: 50
GCID: GC18P021718

Calcium Binding Tyrosine-(Y)-Phosphorylation Regulated

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Calcium Binding Tyrosine-(Y)-Phosphorylation Regulated1 2     CABYRa2
Cancer/Testis Antigen 881 2 3     CABYRc2
FSP22 3 5     CABYRc/d2
Fibrousheathin 21 2     CABYRe2
Calcium-Binding Protein 862 3     Calcium Binding Tyrosine-(Y)-Phosphorylation Regulated (Fibrousheathin 2)2
Fibrousheathin II2 3     Calcium-Binding Tyrosine Phosphorylation-Regulated Protein2
Testis-Specific Calcium-Binding Protein CBP862 3     Calcium-Binding Tyrosine-(Y)-Phosphorylation Regulated (Fibrousheathin 2)2
CBP862 3     fibrousheathin-22
CT882 3     Fibrousheathin-23
FSP-22 3     

External Ids:    HGNC: 155691   Entrez Gene: 262562   Ensembl: ENSG000001540407   OMIM: 6121355   UniProtKB: O759523   

Export aliases for CABYR gene to outside databases

Previous GC identifers: GC18P021611 GC18P021450 GC18P019970 GC18P019972 GC18P018575


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CABYR Gene:
To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational
processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium.
The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the
fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3
has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms
have been found for this gene. (provided by RefSeq, Jul 2013)

GeneCards Summary for CABYR Gene:
CABYR (calcium binding tyrosine-(Y)-phosphorylation regulated) is a protein-coding gene. GO annotations related to this gene include protein kinase binding and calcium ion binding.

UniProtKB/Swiss-Prot: CABYR_HUMAN, O75952
Function: May function as a regulator of both motility- and head-associated functions such as capacitation and the
acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and
isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium

Gene Wiki entry for CABYR Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000018.9  NT_010966.15  NC_018929.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CABYR
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCABYR promoter sequence
   Search Chromatin IP Primers for CABYR

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CABYR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q11.2   Ensembl cytogenetic band:  18q11.2   HGNC cytogenetic band: 18q11.2

CABYR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CABYR gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P021718:  view genomic region     (about GC identifiers)

Start:
21,718,942 bp from pter      End:
21,741,567 bp from pter
Size:
22,626 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CABYR_HUMAN, O75952 (See protein sequence)
Recommended Name: Calcium-binding tyrosine phosphorylation-regulated protein  
Size: 493 amino acids; 52774 Da
Subunit: Interacts with FSCB (By similarity). Isoform 3 self-associates. Isoform 3 and isoform 5 interact with
GSK3B. Isoform 1 does not interact with GSK3B
Secondary accessions: B2R857 Q8WXW5 Q9HAY3 Q9HAY4 Q9HAY5 Q9HCY9
Alternative splicing: 6 isoforms:  O75952-1   O75952-2   O75952-3   O75952-4   O75952-5   O75952-6   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for CABYR: NX_O75952

Explore proteomics data for CABYR at MOPED

Post-translational modifications: 

  • Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are
    phosphorylated by GSK3B in vitro. Dephosphorylation affects its ability to bind calcium1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CABYR Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_036321.2  NP_619584.1  NP_619585.1  NP_722452.1  NP_722453.1  NP_722454.1  

    ENSEMBL proteins: 
     ENSP00000382419   ENSP00000431142   ENSP00000464595   ENSP00000462009   ENSP00000463737  
     ENSP00000462474   ENSP00000399973   ENSP00000463781   ENSP00000432870   ENSP00000317095  
     ENSP00000462811   ENSP00000462748   ENSP00000462947   ENSP00000382421   ENSP00000382404  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003117 cAMP_dep_PK_reg_su_I/II_a/b

    Graphical View of Domain Structure for InterPro Entry O75952

    ProtoNet protein and cluster: O75952

    UniProtKB/Swiss-Prot: CABYR_HUMAN, O75952
    Similarity: Contains 1 RIIa domain


    Find genes that share domains with CABYR           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CABYR_HUMAN, O75952
    Function: May function as a regulator of both motility- and head-associated functions such as capacitation and the
    acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and
    isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium

         Gene Ontology (GO): Selected molecular function terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IDA11820818
    GO:0005515protein binding ----
    GO:0017124SH3 domain binding NAS11820818
    GO:0019899enzyme binding IPI--
    GO:0019901protein kinase binding IEA--
         
    Find genes that share ontologies with CABYR           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CABYR:
     Increased cell number in G2M,  

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CABYR

    miRNA
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    hsa-mir-221-3p (MIRT046975), hsa-mir-222-3p (MIRT046835)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CABYR_HUMAN, O75952: Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localized to fibrous
    sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella
    CABYR_HUMAN, O75952: Isoform 1: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to
    PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic
    CABYR_HUMAN, O75952: Isoform 3: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to
    PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic
    CABYR_HUMAN, O75952: Isoform 5: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to
    PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus5
    cytosol2
    mitochondrion2
    peroxisome1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005730nucleolus ----
    GO:0005737cytoplasm IDA11820818
    GO:0005856cytoskeleton IEA--
    GO:0031514motile cilium IDA18421703

    Find genes that share ontologies with CABYR           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CABYR
    Interactions:

        GeneGlobe Interaction Network for CABYR

    2 Interacting proteins for CABYR (O759523) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    JUNP054123I2D: score=2 
    GSK3BP498413I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001539cilium or flagellum-dependent cell motility IDA18421703
    GO:0048240sperm capacitation NAS11820818

    Find genes that share ontologies with CABYR           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CABYR

    1 HMDB Compound for CABYR    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CABYR gene (6 alternative transcripts): 
    NM_012189.3  NM_138643.2  NM_138644.2  NM_153768.2  NM_153769.2  NM_153770.2  

    Unigene Cluster for CABYR:

    Calcium binding tyrosine-(Y)-phosphorylation regulated
    Hs.511983  [show with all ESTs]
    Unigene Representative Sequence: NM_012189
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000399496(uc021uig.1 uc002kuy.3 uc002kuz.3 uc002kvb.3)
    ENST00000486759(uc010xbb.1 uc002kux.3 uc002kva.3) ENST00000579956
    ENST00000584752 ENST00000585037 ENST00000581872 ENST00000415309 ENST00000577705
    ENST00000463087(uc010dlw.3) ENST00000327201 ENST00000581397 ENST00000579102
    ENST00000582229 ENST00000399499(uc002kvc.3) ENST00000399481
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    Additional mRNA sequence: 

    AF088868.1 AF295037.1 AF295038.1 AF295039.1 AF329634.1 AK225858.1 AK301889.1 AK313243.1 
    AY007205.1 BC011996.1 HM594163.1 HM594167.1 HM594168.1 HM594169.1 HQ659768.1 

    12 DOTS entries:

    DT.303549  DT.95275802  DT.97838128  DT.100779091  DT.75172436  DT.95275804  DT.100021714  DT.40281528 
    DT.97838127  DT.121098002  DT.40254349  DT.100773392 

    Selected AceView cDNA sequences (see all 65):

    AI953149 CD358658 AY007205 NM_138643 AF295038 BM554487 NM_153770 AF295039 
    NM_012189 NM_153769 NM_138644 NM_153768 BI827166 BC011996 AL710861 BI458089 
    BU603004 BX118244 AI656941 BG717462 AA383746 BI560911 AI962197 CD557443 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CABYR (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f · 10g · 10h ^ 11a · 11b ^
    SP1:                                -     -     -                       -     -     -     -     -                                         -     -               
    SP2:                                            -                       -     -     -     -     -                                         -     -               
    SP3:                                -     -     -                       -     -           -     -                                                               
    SP4:                                -     -     -                       -     -                                                                                 
    SP5:                                -     -     -                       -     -                 -                                                               

    ExUns: 12a · 12b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for CABYR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CABYR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAAGCATAAA
    CABYR Expression
    About this image


    CABYR expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Eye (Sensory Organs)
             Retina
    CABYR Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CABYR Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.511983

    UniProtKB/Swiss-Prot: CABYR_HUMAN, O75952
    Tissue specificity: Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed
    in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CABYR gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cabyr1 , 5 calcium-binding tyrosine-(Y)-phosphorylation regulated more1, 5 78.65(n)1
    64.49(a)1
      18 (6.77 cM)5
    711321  NM_001042418.11  NP_001035883.11 
     127413245 
    lizard
    (Anolis carolinensis)
    Reptilia CABYR6
    calcium binding tyrosine-(Y)-phosphorylation regul...
    49(a)
    1 ↔ 1
    4(37884322-37900360)


    ENSEMBL Gene Tree for CABYR (if available)
    TreeFam Gene Tree for CABYR (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CABYR gene

    Find genes that share paralogs with CABYR           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CABYR
    PGOHUM00000237632


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CABYR (see all 612)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1150567031,2
    C,F--21716963(+) CAAGTG/TGGAAT 5 -- us2k11Minor allele frequency- T:0.06WA 118
    rs37605961,2
    C,F,H--21717035(+) CATAGG/AGTAAG 5 -- us2k116Minor allele frequency- A:0.38EA NS NA WA 2340
    rs1399233031,2
    --21717075(+) AGGTAC/GATTTG 5 -- us2k10--------
    rs768066121,2
    C,F--21717159(+) GAAACC/TACATC 5 -- us2k12Minor allele frequency- T:0.15WA EA 238
    rs794938771,2
    C,F--21717220(+) AATTCT/CTGGTT 5 -- us2k11Minor allele frequency- C:0.11WA 118
    rs1132245051,2
    C--21717269(+) TCAGCCAAA/-  
            
    CAGTC
    5 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs16633521,2
    C,H--21717271(+) AGCCAA/C/GACAGT 5 -- us2k15MN NS EA 554
    rs1827462161,2
    --21717411(+) CCAAAA/CGACAC 5 -- us2k10--------
    rs1176776431,2
    C,F--21717450(+) AGCTCA/GGTTCA 6 -- us2k11Minor allele frequency- G:0.01NA 120
    rs1169214701,2
    F--21717455(+) AGTTCA/TTTATG 6 -- us2k11Minor allele frequency- T:0.01NA 120

    HapMap Linkage Disequilibrium report for CABYR (21718942 - 21741567 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CABYR:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv909459CNV Gain21882294
    nsv909460CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612135    OMIM disorders: --


    Find genes that share disorders with CABYR           About GenesLikeMe

    Genetic Association Database (GAD): CABYR
    Human Genome Epidemiology (HuGE) Navigator: CABYR (1 document)

    Export disorders for CABYR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CABYR gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with CABYR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Translation and assembly of CABYR coding region B in fibrous sheath and restriction of calcium binding to coding region A. (PubMed id 16139264)1, 2, 3, 9 Kim Y.-H.... Herr J.C. (Dev. Biol. 2005)
    2. CABYR, a novel calcium-binding tyrosine phosphorylation-regulated fibrous sheath protein involved in capacitation. (PubMed id 11820818)1, 2, 3, 9 Naaby-Hansen S.... Herr J.C. (Dev. Biol. 2002)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. CABYR is a novel cancer-testis antigen in lung cancer. (PubMed id 17317841)1, 3 Luo C....He D. (Clin. Cancer Res. 2007)
    5. Characterization of two non-testis-specific CABYR variants that bind to GSK3beta with a proline-rich extensin-like domain. (PubMed id 15752768)1, 2 Hsu H.-C....Hong Y.-R. (Biochem. Biophys. Res. Commun. 2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    8. The expression and effects the CABYR-c transcript of CABYR gene in hepatocellular carcinoma. (PubMed id 22285430)1 Li H....Shen L. (Bull Cancer 2012)
    9. Expression of the sperm fibrous sheath protein CABYR in human cancers and identification of I+-enolase as an interacting partner of CABYR-a. (PubMed id 21274509)1 Tseng Y.T....Yang C.Y. (Oncol. Rep. 2011)
    10. CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath. (PubMed id 21240291)1 Li Y.F....Herr J.C. (Asian J. Androl. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26256 HGNC: 15569 AceView: CABYR Ensembl:ENSG00000154040 euGenes: HUgn26256
    ECgene: CABYR H-InvDB: CABYR

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CABYR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CABYR gene:
    Search GeneIP for patents involving CABYR

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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