Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CABP2 Gene

protein-coding   GIFtS: 48
GCID: GC11M067286

calcium binding protein 2

 Explore 5 diseases affiliated with
CABP2 via our new
 Human Malady Compendium 
Biological research products
for CABP2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Calcium Binding Protein 21 2
DFNB932
Calcium-Binding Protein 22
CaBP23

External Ids:    HGNC: 13851   Entrez Gene: 514752   Ensembl: ENSG000001677917   OMIM: 6073145   UniProtKB: Q9NPB33   

Export aliases for CABP2 gene to outside databases

Previous GC identifers: GC11M069809 GC11M068982 GC11M067536 GC11M067061 GC11M067043 GC11M063615


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CABP2:
This gene belongs to a subfamily of calcium binding proteins that share similarity to calmodulin. Like calmodulin,
these family members can likely stimulate calmodulin-dependent kinase II and the protein phosphatase calcineurin.
Calcium binding proteins are an important component of calcium mediated cellular signal transduction.(provided by
RefSeq, Nov 2010)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CABP2 gene promoter:
         Egr-3   Spz1   Elk-1   Pax-5   AP-2gamma   Evi-1   PPAR-alpha   PPAR-gamma1   PPAR-gamma2   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCABP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CABP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CABP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.1   Ensembl cytogenetic band:  11q13.2   HGNC cytogenetic band: 11q13.1

CABP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CABP2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M067286:  view genomic region     (about GC identifiers)

Start:
67,286,409 bp from pter      End:
67,290,899 bp from pter
Size:
4,491 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CABP2_HUMAN, Q9NPB3 (See protein sequence)
Recommended Name: Calcium-binding protein 2  
Size: 220 amino acids; 24482 Da
Subcellular location: Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus
Alternative splicing: 2 isoforms:  Q9NPB3-1   Q9NPB3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CABP2: NX_Q9NPB3

CABP2 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins: NP_057450.2  
ENSEMBL proteins: 
 ENSP00000312037   ENSP00000294288   ENSP00000446180  

Human Recombinant Protein Products: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein: CABP2
OriGene Protein Over-expression Lysate: CABP2
OriGene Custom Protein Services for CABP2 
GenScript Custom Purified and Recombinant Proteins Services for CABP2
Novus Biologicals CABP2 Lysate
Browse Sino Biological Recombinant Proteins
Browse ProSpec Recombinant Proteins
Uscn Proteins for CABP2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005794Golgi apparatus IDA19338761
GO:0005886plasma membrane IDA19338761
GO:0048471perinuclear region of cytoplasm IEA--


CABP2 for ontologies           About GeneDecksing



CABP2 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for CABP2 
GenScript Custom Superior Antibodies Services for CABP2
Search for Antibodies for CABP2 at Abcam  
Uscn Antibodies for CABP2
Search ThermoFisher Antibodies for CABP2

Assay Products for CABP2: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Immunoassay Development
Browse OriGene Fluorogenic Cell Assay Kits
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CABP2
Browse Enzo Life Sciences for kits & assays
Uscn ELISAs and CLIAs for CABP2


(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CABP2 for domains           About GeneDecksing

5 InterPro domains/families:
 IPR018247 EF_Hand_1_Ca_BS
 IPR011992 EF-hand-like_dom
 IPR002048 EF_hand_Ca-bd
 IPR018248 EF-hand
 IPR015754 Ca_binding_pro

Graphical View of Domain Structure for InterPro Entry Q9NPB3

ProtoNet protein and cluster: Q9NPB3

UniProtKB/Swiss-Prot: CABP2_HUMAN, Q9NPB3
Similarity: Contains 4 EF-hand domains


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA
Products:
    
Browse 3'-UTR reporter clones for miRNA target validation
Browse MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CABP2
1 QIAGEN miScript miRNA Assays for microRNA that regulate CABP2:
hsa-miR-3714
SwitchGear 3'UTR luciferase reporter plasmidCABP2 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CABP2 (see all 4)
OriGene shRNA RFP: CABP2
OriGene siRNA: CABP2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CABP2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CABP2

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CABP2 (NM_016366)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CABP2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CABP2 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CABP2
Search LifeMap BioReagents cell lines for CABP2

In Situ Assay
Products:
   

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CABP2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005509calcium ion binding IEA--


CABP2 for ontologies           About GeneDecksing



(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1Visual Cycle in Retinal Rods
Visual Cycle in Retinal Rods1.00

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for CABP2
    Visual Cycle in Retinal Rods


Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CABP2

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

4 Interacting proteins for CABP2 (Q9NPB33 ENSP000002942884) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
NMT1P304193, ENSP000002589604I2D: score=2 STRING: ENSP00000258960
PPP3R1P630983, ENSP000002343104I2D: score=2 STRING: ENSP00000234310
CAMK2GENSP000003190604STRING: ENSP00000319060
--Q132803I2D: score=1 
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007165signal transduction TAS10625670


CABP2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CABP2
Search CenterWatch for drugs/clinical trials and news about CABP2 

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CABP2 gene (2 alternative transcripts): 
NM_016366.2  NM_031204.2  

Unigene Cluster for CABP2:

Calcium binding protein 2
Hs.278984  [show with all ESTs]
Unigene Representative Sequence: AB593136
3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000353903 ENST00000294288 ENST00000545205(uc001omc.1 uc001ome.1)


miRNA
Products:
     
Browse 3'-UTR reporter clones for miRNA target validation
Browse OriGene MicroRNA Expression Plasmids
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CABP2
1 QIAGEN miScript miRNA Assays for microRNA that regulate CABP2:
hsa-miR-3714
SwitchGear 3'UTR luciferase reporter plasmidCABP2 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CABP2 (see all 4)
OriGene shRNA RFP: CABP2
OriGene siRNA: CABP2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CABP2
Clone
Products:
     
OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
GenScript: all cDNA clones in your preferred vector: CABP2 (NM_016366)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CABP2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CABP2 
Primer
Products:
    
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CABP2
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CABP2
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CABP2
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CABP2

Additional cDNA sequence: 

AB593136.1 AF169154.1 BC018476.1 

1 DOTS entry:

DT.91657280 

7 AceView cDNA sequences:

BC018476 BX280663 NM_016366 NM_031204 AF169154 BE780276 BM686898 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for CABP2    About this scheme

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1:                                                      
SP2:                                                      


ECgene alternative splicing isoforms for CABP2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CABP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTCCTTGAAG

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)

About this image

CABP2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell 
Tissue Anatomical Compartment CellCategory (developmental path)
EyeInner Nuclear LayerType1 Off Cone Bipolar CellsBipolar, Retina
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See CABP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CABP2

SOURCE GeneReport for Unigene cluster: Hs.278984

UniProtKB/Swiss-Prot: CABP2_HUMAN, Q9NPB3
Tissue specificity: Retina

    SABiosciences Custom PCR Arrays for CABP2
Primer
Products:
OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CABP2
Browse OriGene validated miRNA SYBR primer pairs
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CABP2
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CABP2
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CABP2
In Situ
Assay Products:
 

 
Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CABP2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CABP2 gene from 4/10 species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chicken
(Gallus gallus)
Aves CABP41 calcium binding protein 4 76.95(n)
73.36(a)
  429967  XM_427524.3  XP_427524.3 
lizard
(Anolis carolinensis)
Reptilia CABP46
--
46(a)
1 → many
1(93363954-93379594)
zebrafish
(Danio rerio)
Actinopterygii zgc:1123001 zgc:112300 73.3(n)
75.57(a)
  572226  NM_001030268.1  NP_001025439.1 
fruit fly
(Drosophila melanogaster)
Insecta CG135266
--
27(a)
1 → many
2R(18642745-18643401)


ENSEMBL Gene Tree for CABP2 (if available)
TreeFam Gene Tree for CABP2 (if available) 

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CABP2 gene
CALML32  CABP52  CABP12  TNNC12  CALM32  CABP42  CALM12  TNNC22  
CALML62  CALML52  CALML42  CABP72  CALN12  CALM22  
18/25 SIMAP similar genes for CABP2 using alignment to 3 protein entries:     CABP2_HUMAN (see all proteins) (see all similar genes):
CABP5    CABP1    CALN1    CALM3    CABP4    CALM1
CALML3    CALM2    S100Z    CALML5    TNNC1    CETN1
TNNC2    CETN2    MYL9    MYL1    PPP3R1    MYL6

CABP2 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/125 NCBI SNPs in CABP2 are shown (see all 125    About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs800963311,2
F,--63615267(+) CAAGCT/CTGGGA 1 -- ds50011Minor allele frequency- C:0.02WA 118
rs6522211,2
H--63616026(-) TGTTTT/GTCCCC 1 -- int1 trp34Minor allele frequency- G:0.00NS EA 418
rs6853501,2
--63616679(+) AGCCCC/TTCACT 1 -- int10--------
rs753154901,2
F--63617303(+) CATTGT/ACACTC 1 -- int11Minor allele frequency- A:0.33NA 6
rs797620211,2
--63617636(+) CTGGAC/GTGCTT 1 -- int10--------
rs22761191,2
C,H--63617658(-) CCCCCG/ACTGGG 1 -- int12Minor allele frequency- A:0.01NS NA 172
rs1129720691,2
--63618884(+) TGGGCC/TGTCCT 1 -- int12Minor allele frequency- T:0.03CSA WA 120
rs735060741,2
C,--63620163(+) AGATCG/AGGGGC 1 -- us2k12Minor allele frequency- A:0.24WA 120
rs122815051,2
C,H--63620208(+) GGGTCC/ATAATC 1 -- us2k14Minor allele frequency- A:0.00NS EA 406
rs1153681621,2
C,--63620770(+) TCCCAT/CTGGAC 1 -- us2k11Minor allele frequency- C:0.01WA 118

HapMap Linkage Disequilibrium report for CABP2 (67286409 - 67290899 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CABP2
     1 CNV: 5275
Human Gene Mutation Database (HGMD): CABP2

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CABP2
DNA2.0 Custom Variant and Variant Library Synthesis for CABP2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CABP2 for disorders           About GeneDecksing

OMIM gene information: 607314    OMIM disorders: --

UniProtKB/Swiss-Prot: CABP2_HUMAN, Q9NPB3
  • Defects in CABP2 are the cause of deafness, autosomal recessive, 93 (DFNB93) [MIM:614899]. A form of
  • non-syndromic deafness characterized by stable, bilateral, symmetric, prelingual moderate to severe deafness. Hearing
    impairment is slightly more pronounced in the mid-frequencies, resulting in a distinctive shallow U-shaped audiogram

    5 diseases for CABP2:    About MalaCards
    non-hodgkin lymphoma    amebiasis    hodgkin's lymphoma    pulmonary function
    retinitis

    1 disease from the University of Copenhagen DISEASES database for CABP2:
    Amebiasis

    Export disorders for CABP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CABP2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with CABP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin. (PubMed id 10625670)1, 2, 3 Haeseleer F....Palczewski K. (2000)
    2. Membrane targeting of the EF-hand containing calcium-sensing proteins CaBP7 and CaBP8. (PubMed id 19338761)1, 2 McCue H.V.... Haynes L.P. (2009)
    3. Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease. (PubMed id 11108966)1, 2 Sokal I....Palczewski K. (2000)
    4. A mutation in CABP2, expressed in cochlear hair cells, causes autosomal-recessive hearing impairment. (PubMed id 22981119)2 Schrauwen I.... Van Camp G. (2012)
    5. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)1 Oshikawa M.... Kato S. (2011)
    6. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Functional roles and efficiencies of the thioredoxin boxes of calcium-binding proteins 1 and 2 in protein folding. (PubMed id 11415439)1 Kramer B....Soling H.D. (2001)
    9. Secreted modular calcium-binding protein 2 haplotypes are associated with pulmonary function. (PubMed id 17204727)9 Wilk J.B....Karamohamed S. (2007)
    10. Xenopus SMOC-1 Inhibits bone morphogenetic protein si gnaling downstream of receptor binding and is essential for postgastrulation de velopment in Xenopus. (PubMed id 19414592)9 Thomas J.T....Moos M. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51475 HGNC: 1385 AceView: CABP2 Ensembl:ENSG00000167791 euGenes: HUgn51475
    ECgene: CABP2 H-InvDB: CABP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CABP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CABP2 gene:
    Search GeneIP for patents involving CABP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for CABP2  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CABP2   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CABP2  
     OriGene Protein Over-expression Lysate for CABP2   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for CABP2   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CABP2  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for CABP2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CABP2   OriGene Custom Protein Services for CABP2  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CABP2
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CABP2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CABP2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CABP2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CABP2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CABP2
     GenScript Custom Purified and Recombinant Proteins Services for CABP2 GenScript cDNA clones with any tag delivered in your preferred vector for CABP2
     GenScript Custom Assay Services for CABP2 GenScript Custom Superior Antibodies Services for CABP2
     GenScript Custom overexpressing Cell Line Services for CABP2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CABP2 promoter
     Search Chromatin IP Primers for CABP2
     RT2 qPCR Primer Assay in human, mouse, rat CABP2
     Search GNC Networks for CABP2
     SABiosciences PCR Arrays including human, mouse, rat CABP2
     Search Tocris compounds for CABP2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CABP2 lysates
     Search for Antibodies for CABP2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for CABP2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     CABP2 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for CABP2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for CABP2
     SwitchGear 3'UTR luciferase reporter plasmids for CABP2
     SwitchGear Promoter luciferase reporter plasmids for CABP2
     Search ThermoFisher Antibodies for CABP2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CABP2
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CABP2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4