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Aliases for CABCOCO1 Gene

Aliases for CABCOCO1 Gene

  • Ciliary Associated Calcium Binding Coiled-Coil 1 2 3
  • C10orf107 3 4 5
  • Calcium-Binding Coiled-Coil Protein-1 2 3
  • Chromosome 10 Open Reading Frame 107 2 5
  • Uncharacterized Protein C10orf107 3
  • BA63A2.1 3

External Ids for CABCOCO1 Gene

Previous HGNC Symbols for CABCOCO1 Gene

  • C10orf107

Summaries for CABCOCO1 Gene

GeneCards Summary for CABCOCO1 Gene

CABCOCO1 (Ciliary Associated Calcium Binding Coiled-Coil 1) is a Protein Coding gene.

Additional gene information for CABCOCO1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CABCOCO1 Gene

Genomics for CABCOCO1 Gene

Regulatory Elements for CABCOCO1 Gene

Enhancers for CABCOCO1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10H061757 1.4 Ensembl ENCODE dbSUPER 35.7 +95.0 95005 1 TBL1XR1 ZSCAN4 GLI4 RAD21 BRCA1 ZEB1 RFX5 ZNF366 RCOR1 FOS CABCOCO1 GC10P061754 ENSG00000233643
GH10H061750 1.5 Ensembl ENCODE dbSUPER 24.8 +89.4 89367 3 HDGF PKNOX1 ATF1 ZNF2 CBX5 ELK1 ZNF143 ATF7 RUNX3 REST CABCOCO1 GC10P061754 ENSG00000272592
GH10H061635 0.9 Ensembl ENCODE 33.6 -27.3 -27275 2 STAT1 JUN CEBPB CEBPG EP300 JUND STAT3 FOS PRDM1 ZNF558 CABCOCO1 GC10M061462
GH10H061662 0.7 ENCODE 41.9 +0.1 91 0 ZNF202 CTCF RFX1 SIN3A ZBTB8A NR3C1 BMI1 RAD21 RFX3 ZBTB33 CABCOCO1 ENSG00000272592
GH10H061627 1.2 Ensembl ENCODE 20.3 -34.1 -34144 2 TBP PKNOX1 FOXA2 ZSCAN4 INSM2 SIN3A RAD21 BRCA1 RFX5 ZNF366 CABCOCO1 GC10M061462
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CABCOCO1 on UCSC Golden Path with GeneCards custom track

Promoters for CABCOCO1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000028679 49 799 ZNF202 CTCF RFX1 SIN3A ZBTB8A NR3C1 BMI1 RAD21 RFX3 ZBTB33

Genomic Location for CABCOCO1 Gene

Chromosome:
10
Start:
61,662,952 bp from pter
End:
61,766,766 bp from pter
Size:
103,815 bases
Orientation:
Plus strand

Genomic View for CABCOCO1 Gene

Genes around CABCOCO1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CABCOCO1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CABCOCO1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CABCOCO1 Gene

Proteins for CABCOCO1 Gene

  • Protein details for CABCOCO1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVU9-CJ107_HUMAN
    Recommended name:
    Uncharacterized protein C10orf107
    Protein Accession:
    Q8IVU9
    Secondary Accessions:
    • Q5T1B8

    Protein attributes for CABCOCO1 Gene

    Size:
    208 amino acids
    Molecular mass:
    23883 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CABCOCO1 Gene

Post-translational modifications for CABCOCO1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CABCOCO1 Gene

No data available for DME Specific Peptides for CABCOCO1 Gene

Domains & Families for CABCOCO1 Gene

Gene Families for CABCOCO1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CABCOCO1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CABCOCO1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CABCOCO1: view

No data available for UniProtKB/Swiss-Prot for CABCOCO1 Gene

Function for CABCOCO1 Gene

Phenotypes From GWAS Catalog for CABCOCO1 Gene

genes like me logo Genes that share phenotypes with CABCOCO1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CABCOCO1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CABCOCO1 Gene

Localization for CABCOCO1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CABCOCO1 gene
Compartment Confidence
nucleus 2
cytosol 2
mitochondrion 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Centrosome (1)
  • Cytosol (1)
  • Nucleoplasm (1)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CABCOCO1 Gene

Pathways & Interactions for CABCOCO1 Gene

SuperPathways for CABCOCO1 Gene

No Data Available

Interacting Proteins for CABCOCO1 Gene

Gene Ontology (GO) - Biological Process for CABCOCO1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CABCOCO1 Gene

Drugs & Compounds for CABCOCO1 Gene

No Compound Related Data Available

Transcripts for CABCOCO1 Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CABCOCO1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CABCOCO1 Gene

No ASD Table

Relevant External Links for CABCOCO1 Gene

GeneLoc Exon Structure for
CABCOCO1
ECgene alternative splicing isoforms for
CABCOCO1

Expression for CABCOCO1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of CABCOCO1 Gene:

CABCOCO1
genes like me logo Genes that share expression patterns with CABCOCO1: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CABCOCO1 Gene

Orthologs for CABCOCO1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CABCOCO1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C10H10orf107 33
  • 98.56 (n)
C10orf107 34
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C4H10orf107 33
  • 88.94 (n)
C10orf107 34
  • 60 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C28H10orf107 33
  • 88.67 (n)
C10ORF107 34
  • 47 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia RGD1306739 33
  • 78.53 (n)
mouse
(Mus musculus)
Mammalia 1700040L02Rik 33 16 34
  • 77.56 (n)
oppossum
(Monodelphis domestica)
Mammalia C10orf107 34
  • 46 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C10orf107 34
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves C6H10ORF107 33
  • 61.05 (n)
C10orf107 34
  • 36 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 54 (a)
OneToMany
-- 34
  • 34 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100486238 33
  • 59.35 (n)
zebrafish
(Danio rerio)
Actinopterygii zgc:194508 33
  • 49.75 (n)
C12H10orf107 34
  • 17 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 17 (a)
OneToOne
Species where no ortholog for CABCOCO1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CABCOCO1 Gene

ENSEMBL:
Gene Tree for CABCOCO1 (if available)
TreeFam:
Gene Tree for CABCOCO1 (if available)

Paralogs for CABCOCO1 Gene

No data available for Paralogs for CABCOCO1 Gene

Variants for CABCOCO1 Gene

Sequence variations from dbSNP and Humsavar for CABCOCO1 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000039755 -- 61,737,358(+) GAGTG(C/T)AAATT intron-variant
rs1000039827 -- 61,683,659(+) TAAGT(A/C)TAGTA intron-variant
rs1000067522 -- 61,687,162(+) ATAAT(A/G)TCATA intron-variant
rs1000071909 -- 61,758,845(+) TCAAT(A/G)CAAAA intron-variant
rs1000115368 -- 61,729,374(+) TGTTC(A/C/T)ATGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CABCOCO1 Gene

Variant ID Type Subtype PubMed ID
dgv42n21 CNV loss 19592680
esv1510214 CNV insertion 17803354
esv2737507 CNV deletion 23290073
esv3623486 CNV loss 21293372
nsv1113304 CNV deletion 24896259
nsv1140453 CNV tandem duplication 24896259

Variation tolerance for CABCOCO1 Gene

Residual Variation Intolerance Score: 47.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.63; 13.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CABCOCO1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CABCOCO1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CABCOCO1 Gene

Disorders for CABCOCO1 Gene

Relevant External Links for CABCOCO1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CABCOCO1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CABCOCO1

No disorders were found for CABCOCO1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CABCOCO1 Gene

Publications for CABCOCO1 Gene

  1. CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum. (PMID: 26990073) Kawashima A … Okamura N (Molecular reproduction and development 2016) 2 3 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie AG … Butte NF (PloS one 2012) 3 60

Products for CABCOCO1 Gene

Sources for CABCOCO1 Gene

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