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CA9 Gene

protein-coding   GIFtS: 65

GC09P035663
carbonic anhydrase IX
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
Services    

Aliases &
Descriptions
for CA9

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CA-IX 3
CAIX 1, 2, 3
EC 4.2.1.1 3
G250 3
MN 1, 2, 3, 5
OTTHUMP00000022773 2
P54/58N 3
pMW1 3
Descriptions
Carbonate dehydratase IX 3
Membrane antigen MN 3
RCC-associated antigen G250 3
RCC-associated protein G250 2
Renal cell carcinoma-associated antigen G250 3
carbonic anhydrase IX 2, 3
carbonic dehydratase 2
External Ids
HGNC: 13831
Entrez Gene: 7682
UniProtKB: Q167903
Ensembl: ENSG000001071597
Search outside databases for aliases for CA9 gene

Previous GC identifers: GC09P035986 GC09P035843

Summaries
for CA9

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for CA9:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible
hydration of carbon dioxide. They participate in a variety of biological processes, including
respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous
humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue
distribution and in their subcellular localization. CA IX is a transmembrane protein and the only
tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell
carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved
in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ
hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq]

UniProtKB/Swiss-Prot: CAH9_HUMAN, Q16790
Function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in
the control of cell proliferation and transformation. Appears to be a novel specific biomarker for
a cervical neoplasia

Gene Wiki entry for CA9

Genomic Location
for CA9

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the CA9 gene  

Entrez Gene cytogenetic band: 9p13-p12   Ensembl cytogenetic band:  9p13.3   HGNC cytogenetic band: 9p12

CA9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P035663:     (about GC identifiers)

Start:
 35,663,853 bp from pter
End:
 35,671,152 bp from pter
Size:
 7,300 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000009.10  NT_008413.17  

Proteins
for CA9

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: CAH9_HUMAN, Q16790 (See protein sequence)
Recommended Name: Carbonic anhydrase 9 precursor  
Size: 459 amino acids; 49698 Da
Cofactor: Zinc (By similarity)
Subunit: Forms oligomers linked by disulfide bonds
Subcellular location: Nucleus. Nucleus, nucleolus. Cell membrane; Single-pass type I membrane
protein. Cell projection, microvillus membrane; Single-pass type I membrane protein. Note=Found on
the surface microvilli and in the nucleus, particularly in nucleolus
PDB structures from and Proteopedia :
2HKF (3D)    
Secondary accessions: Q5T4R1

Post-translational modifications:

  • Asn-346 bears high-mannose type glycan structures1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_001207.2  

    ENSEMBL proteins: 
    ENSP00000367608 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Browse Human Recombinant Proteins at Sigma-Aldrich  
    R&D Systems Recombinant & Natural Proteins for CA9 (Carbonic Anhydrase IX)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (Carbonic Anhydrase IX Precursor, Carbonic Anhydrase IX)
    Human Recombinant Proteins from Abnova (CA9)
                    Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 

    4 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IEA--
    GO:0005886 plasma membrane IEA--
    GO:0016021 integral to membrane TAS8661007
    GO:0042995 cell projection IEA--
    About this table

    Antibodies for CA9: 
    Browse Antibodies Central at Invitrogen
    Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Sigma-Aldrich Antibodies for CA9
    R&D Systems Antibodies for CA9 (Carbonic Anhydrase IX)
    Antibodies from Abcam (Carbonic Anhydrase IX Precursor, Carbonic Anhydrase IX), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (CA9)
    Novus Biologicals Antibodies for CAH9

    Assays for CA9: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    R&D Systems ELISAs for CA9 (Carbonic Anhydrase IX)         (see all)
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for CA9

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro domains/families:
     IPR001148 Carbonic_anhydrase_a-class_cat
     IPR018338 Carbonic_anhydrase_a-class_CS
     IPR018429 Carbonic_anhydrase_CA9


       GeneDecks  CA9 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q16790

    ProtoNet protein and cluster: Q16790

    1 Blocks protein family: IPB001148 Carbonic anhydrase

    UniProtKB/Swiss-Prot: CAH9_HUMAN, Q16790
    Similarity: Belongs to the alpha-carbonic anhydrase family

    Gene Function
    for CA9

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CA9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (CA9)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001216

                  Applied Biosystems Silencer® siRNAs for CA9

                  Sigma-Aldrich siRNA and siRNA Panels for CA9  
                         Sigma-Aldrich shRNA for CA9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for CA9
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001216
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001216
                                     untagged cDNA clone in CMV expression vector: NM_001216 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_001216

    UniProtKB/Swiss-Prot: CAH9_HUMAN, Q16790
    Function: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in
    the control of cell proliferation and transformation. Appears to be a novel specific biomarker for
    a cervical neoplasia
    Catalytic activity: H(2)CO(3) = CO(2) + H(2)O
    Induction: By hypoxia
    Enzyme Number (IUBMB): EC 4.2.1.1 

    Genatlas biochemistry entry for CA9:
    carbonic anhydrase 9,MN/CA antigen expressed in Hela cells and some human carcinomas

    3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Car9):

    digestive/alimentaryendocrine/exocrine glandlethality-prenatal/perinatal

    4 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004089 carbonate dehydratase activity TAS8661007
    GO:0008270 zinc ion binding IEA--
    GO:0016829 lyase activity IEA--
    GO:0046872 metal ion binding IEA--
    About this table

    Pathways & Interactions
    for CA9

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    1 Sigma-Aldrich "Your Favorite Gene" Pathway for  CA9  (Your Favorite Gene powered by Ingenuity) 
     Nitrogen Metabolism

       GeneDecks  CA9 for the pathways selected above  
    About GeneDecksing

    1 Kegg Pathway  (Kegg details for CA9):
     hsa00910 Nitrogen metabolism

       GeneDecks  CA9 for the pathways selected above  
    About GeneDecksing
     Gene Network CentralTM Interacting Genes and Proteins Network for  CA9 


    5/13 Interacting proteins for CA9 (ENSP000003676083) via UniProtKB, MINT, and/or STRING (see all 13 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIF1AENSP000003380183STRING (score=.982)
    SETD2ENSP000003324153STRING (score=.953)
    ARNTENSP000003156373STRING (score=.937)
    HIF1ANENSP000002991633STRING (score=.867)
    SILVENSP000003539403STRING (score=.852)
    About this table

    3 Gene Ontology (GO) biological process terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002009 morphogenesis of an epithelium IEA--
    GO:0006730 one-carbon compound metabolic process IEA--
    GO:0046903 secretion IEA--
    About this table

    Drugs & Compounds
    for CA9

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Sigma-Aldrich Small Molecules for CA9:
    Inhibitor

    Browse Tocris compounds for CA9
    10/13 Novoseek chemical compound relationships for CA9 gene (see all 13 )
    Compound   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    pimonidazole 88.77 45 16618579 (5), 16242253 (4), 12460928 (4), 16024110 (4) (see all 16)
    bicarbonate 42.98 10 17652430 (2), 15010840 (2), 11310605 (1), 15500003 (1) (see all 7)
    carbon dioxide 42.21 10 16310354 (1), 15951534 (1), 15500003 (1), 14567991 (1) (see all 8)
    oxygen 34.66 20 16098620 (2), 17512623 (2), 16243791 (2), 12937836 (2) (see all 12)
    glucose 26.86 38 17382701 (4), 15010840 (2), 14520462 (1), 16098620 (1) (see all 26)
    p003 5.71 1 12618881 (1)
    tyrosine 4.44 2 16310354 (2)
    calcium 3.10 3 15322093 (1), 18381358 (1), 14567991 (1)
    hydrogen 0.00 3 14712082 (1), 11676494 (1)
    progesterone 0.00 3 18194560 (2), 17085655 (1)
    About this table


    Transcripts
    for CA9

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (CA9)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (CA9)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001216

                  Sigma-Aldrich siRNA and siRNA Panels for CA9  
                         Sigma-Aldrich shRNA for CA9  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_001216  

    REFSEQ mRNAs for CA9 gene: 

    NM_001216.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_001216  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_001216
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_001216
                                     untagged cDNA clone in CMV expression vector: NM_001216 

    Additional cDNA sequence: 

    AJ010588.1 BC014950.1 CR590646.1 CR597234.1 CR616345.1 CR620502.1 EF122496.1 X66839.1 

    7 DOTS entries:

    DT.208212  DT.100745009  DT.97826490  DT.97837714  DT.100751488  DT.121152882  DT.91730964 

    24/78 AceView cDNA sequences (see all 78 ):

    BM052971 CK903817 BM052696 BM052891 BM052647 CR616345 AL542336 NM_001216 
    AW449513 CR590646 BI964215 X66839 AI307631 AI925646 AI791726 AL558378 
    CR597234 BI963901 AL554705 BM826222 AW136118 CR620502 BG386425 AI769526 

    highest scoring ESTs for CA9:

    X66839 AA879425 AI023541 AI032380 AI241681 AI318570 AI400286 AI538585 AI760914 AI769526 

    Unigene Cluster for CA9:

    Carbonic anhydrase IX
    Hs.63287  [show with all ESTs]
    Unigene Representative Sequence: BC014950


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CA9

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11
    SP1:                                                                                    
    SP2:                                      -                                             
    SP3:                                                        -                           
    SP4:        -                                                                           

    About this scheme

    ECgene alternative splicing isoforms for CA9

    1 Ensembl transcript including schematic representation:
    ENST00000378357  

    Expression
    for CA9

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    CA9 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for CA9

    1 / 2 / 3

    3 probe-sets matching CA9 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		40309_at2, 3 U95-A 1 1.00 1.00 1.00 1.00 X66839 1.00 1.00 1.00 1

    		205199_at2, 3 U133-A 1 1.00 1.00 -- -- NM_001216 0.60 1.00 0.82 1

    		205199_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: GCTCCCCTGT

    SOURCE GeneReport for Unigene cluster: Hs.63287

    Expression variation in blood from EXPOLDB for CA9

    UniProtKB/Swiss-Prot: CAH9_HUMAN, Q16790
    Tissue specificity: Expressed primarily in carcinoma cells lines. Expression is restricted to very
    few normal tissues and the most abundant expression is found in the epithelial cells of gastric
    mucosa

    Orthologs
    for CA9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for CA9 gene from 5/9 species (see all 9 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 CA91   -- carbonic anhydrase IX 85.91(n)
    82.35(a)    		 611933  XM_849656.1  XP_854749.1 
    chimpanzee
    (Pan troglodytes)    		 CA91   -- carbonic anhydrase IX 99.26(n)
    99.12(a)    		 473223  XM_528593.2  XP_528593.2 
    cow
    (Bos taurus)    		 CA91   -- carbonic anhydrase IX 84.94(n)
    83(a)    		 511923  XM_866456.2  XP_871549.2 
    rat
    (Rattus norvegicus)    		 Car91   -- carbonic anhydrase 9 80.61(n)
    75.17(a)    		 313495  XM_233380.4  XP_233380.4 
    mouse
    (Mus musculus)    		 Car91, 5 45
    		 carbonic anhydrase 91, 5 79.54(n)1
    73.56(a)1    		 2300991  NM_139305.21  NP_647466.21 
     AB0863225  AJ2458575  (see all 14)
    About this table        Species with no ortholog for CA9

    ENSEMBL Gene Tree for CA9

    Paralogs
    for CA9

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for CA9 gene
    CA122  CA62  CA142  

    SNPs/Variants
    for CA9

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/55 NCBI SNPs in CA9 are shown (see all 55 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 48)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 9 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs15385351,2
    		A,C,F,H,O35671299(+) TGTTCC/TTCCTT 1 -- ng318Minor allele frequency- N:0.00EA NA EU WA 634
    rs20716761,2
    		A,C,F,H35664053(+) TTCTGG/ATGCCT 1 M/V mis18Minor allele frequency- A:0.41EA EU WA NA 2050
    rs20716751,2
    		C,F,H35663891(+) ACCCAG/ACTCTC 1 -- ng51 ese312Minor allele frequency- A:0.23EA NA EU WA 2446
    rs37636291,2
    		C,F,H35671200(+) GGTATT/CTGAAT 1 -- ng3111Minor allele frequency- C:0.06NA EU EA WA 978
    rs48799241,2
    		C,F,H35671368(+) CTCCTT/CGTCTC 1 -- ng318Minor allele frequency- C:0.15EU EA WA 824
    rs38290781,2
    		C,F,H35669251(+) CTTCCA/GATATG 1 Q/R mis18Minor allele frequency- G:0.04EU EA WA 838
    --
    rs10486381,2
    		C,F35671122(+) ACTGCC/AAAGAA 1 -- ut319Minor allele frequency- A:0.10MN EA NA EU WA 820
    --
    rs48786261,2
    		A,C35662236(+) gctacC/Tcagga 1 -- ng510--------
    rs125531731,2
    		A,C,F,H35664101(+) CCCCCT/CTGGGA 1 L/L syn14Minor allele frequency- C:0.21EU EA WA 412
    --
    rs23013701,2
    		C35665852(+) CCGGCC/GCTGCG 1 A/A syn1 ese30--------
    About this table

    HapMap Linkage Disequilibrium images for CA9 (up to first 250kb)

    Disorders & Mutations
    for CA9

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 603179

    10/43 Novoseek disease relationships for CA9 gene (see all 43 )

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    renal clear cell carcinoma 81.66 21 17382701 (3), 15126876 (2), 17947723 (2), 18695901 (2) (see all 11)
    carcinoma renal cell 76.25 34 17382701 (2), 16905977 (2), 16042714 (1), 15717944 (1) (see all 28)
    tumors 64.63 353 16024110 (8), 11522632 (7), 19074859 (6), 16428489 (6) (see all 99)
    metastatic renal cell carcinoma 63.41 2 12941820 (1), 16648493 (1)
    aggressiveness 60.84 1 15935515 (1)
    renal cancer 60.22 12 15897568 (4), 12576453 (2), 16310354 (1), 18430120 (1) (see all 5)
    carcinoma 51.01 48 14572156 (3), 18941400 (3), 9395919 (2), 15754010 (2) (see all 27)
    solid tumor 50.62 5 12154057 (1), 16416108 (1), 17724612 (1)
    neck cancer 49.50 2 11705854 (2)
    cervical carcinoma 47.91 6 12687273 (3), 14654550 (1), 18055005 (1)
    About this table

    Human Genome Epidemiology Navigator: CA9 (1 document)

    Medical News
    for CA9

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for CA9

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/298 PubMed articles for CA9 gene (see all 298 ):

    Search for CA9

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CA9

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 768 HGNC: 1383 AceView: CA9 Ensembl:ENSG00000107159 euGenes: HUgn768
    ECgene: CA9 H-InvDB: CA9

    Other Databases showing CA9

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing CA9

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for CA9 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for CA9

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for CA9

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for CA9:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
      Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for CA9-related products

     Millipore Custom Antibody & Bulk Services
     Millipore Preclinical / Clinical Development Services
     Millipore Immunoassay Services
     Millipore Target Screening & Profiling Services


     Predesigned and custom siRNAs for CA9 Antibodies for CA9
     Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
     Lentivirus-delivered shRNAs for CA9 Small molecules for CA9
     "Your Favorite Gene" Pathwaysfeedback


      
     Antibodies   Primer Pairs  
     Cell Culture Products   ELISAs  
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