Aliases for CA5A Gene
External Ids for CA5A Gene
Previous HGNC Symbols for CA5A Gene
Previous GeneCards Identifiers for CA5A Gene
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2. [provided by RefSeq, Jul 2008]
GeneCards Summary for CA5A Gene
CA5A (Carbonic Anhydrase 5A) is a Protein Coding gene. Diseases associated with CA5A include hyperammonemia due to carbonic anhydrase va deficiency and hyperammonemic encephalopathy due to carbonic anhydrase va deficiency. Among its related pathways are Metabolism and Nitrogen metabolism. GO annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA14.
UniProtKB/Swiss-Prot for CA5A Gene
Reversible hydration of carbon dioxide. Low activity.