Aliases for CA14 Gene
External Ids for CA14 Gene
Previous GeneCards Identifiers for CA14 Gene
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XIV is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles. [provided by RefSeq, Jul 2008]
GeneCards Summary for CA14 Gene
CA14 (Carbonic Anhydrase 14) is a Protein Coding gene. Diseases associated with CA14 include Proximal Renal Tubular Acidosis. Among its related pathways are Nitrogen metabolism and Metabolism. GO annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA12.
UniProtKB/Swiss-Prot for CA14 Gene
Reversible hydration of carbon dioxide.