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CA11 Gene

protein-coding   GIFtS: 54
GCID: GC19M049141

Carbonic Anhydrase XI

  Search for CA11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Carbonic Anhydrase XI1 2     CA-RP II2 3
Carbonic Anhydrase-Related Protein 21 2 3     CARP XI2 3
CA-RP XI1 3     CARP23 5
Carbonic Anhydrase-Related Protein XI1 2     CARPX12
CA-XI2 3     Carbonic Anhydrase-Related Protein 112
CARP-22 3     

External Ids:    HGNC: 13701   Entrez Gene: 7702   Ensembl: ENSG000000631807   OMIM: 6046445   UniProtKB: O754933   

Export aliases for CA11 gene to outside databases

Previous GC identifers: GC19M049785 GC19M049509 GC19M053817 GC19M053833 GC19M045520


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CA11 Gene:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of
carbon dioxide. They participate in a variety of biological processes, including respiration, calcification,
acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric
acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely
a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with
catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with
two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a
general role in the central nervous system. (provided by RefSeq, Jul 2008)

GeneCards Summary for CA11 Gene:
CA11 (carbonic anhydrase XI) is a protein-coding gene. GO annotations related to this gene include carbonate dehydratase activity. An important paralog of this gene is CA10.

UniProtKB/Swiss-Prot: CAH11_HUMAN, O75493
Function: Does not have a catalytic activity

Gene Wiki entry for CA11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CA11 gene promoter:
         CREB   AP-1   deltaCREB   ATF-2   Nkx2-5   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCA11 promoter sequence
   Search Chromatin IP Primers for CA11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CA11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.3

CA11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CA11 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M049141:  view genomic region     (about GC identifiers)

Start:
49,141,199 bp from pter      End:
49,149,569 bp from pter
Size:
8,371 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CAH11_HUMAN, O75493 (See protein sequence)
Recommended Name: Carbonic anhydrase-related protein 11 precursor  
Size: 328 amino acids; 36238 Da
Secondary accessions: O60596 Q6FHI1 Q9UEC4

Explore the universe of human proteins at neXtProt for CA11: NX_O75493

Explore proteomics data for CA11 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn118, Asn170, Asn260
  • Modification sites at PhosphoSitePlus

  • See CA11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001208.2  
    ENSEMBL proteins: 
     ENSP00000084798   ENSP00000469234  

    CA11 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CA11

     
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    CA11 Assay Products:

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    Search eBioscience for ELISAs for CA11 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CA: Carbonic anhydrases

    3 InterPro protein domains:
     IPR001148 Carbonic_anhydrase_a
     IPR023561 Carbonic_anhydrase_a-class
     IPR018423 CA10/11

    Graphical View of Domain Structure for InterPro Entry O75493

    ProtoNet protein and cluster: O75493

    1 Blocks protein domain: IPB001148 Carbonic anhydrase

    UniProtKB/Swiss-Prot: CAH11_HUMAN, O75493
    Similarity: Belongs to the alpha-carbonic anhydrase family


    Find genes that share domains with CA11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAH11_HUMAN, O75493
    Function: Does not have a catalytic activity

         Genatlas biochemistry entry for CA11:
    acatalytic carbonic anhydrase related peptide XI,embedded between the secretor cluster and DBP,expressed
    abundantly in the brain (moderatly in spinal cord and thyroid,cerebral cortex,cerebellum putamen)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004089NOT carbonate dehydratase activity TAS9878252
         
    Find genes that share ontologies with CA11           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Car11 (no phenotypes)

    Find genes that share phenotypes with CA11           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CA11
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CA11
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CA11

    miRNA
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    miRTarBase miRNAs that target CA11:
    hsa-mir-26b-5p (MIRT028867)

    Block miRNA regulation of human, mouse, rat CA11 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate CA11:
    hsa-miR-633 hsa-miR-204 hsa-miR-211
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CA11

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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA11

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CAH11_HUMAN, O75493: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular3
    plasma membrane2
    cytoskeleton1
    lysosome1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0016323basolateral plasma membrane IEA--

    Find genes that share ontologies with CA11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CA11
    Interactions:

        Search GeneGlobe Interaction Network for CA11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for CA11 (O754933 ENSP000000847984) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RIPK1Q135463, ENSP000002598084I2D: score=1 STRING: ENSP00000259808
    MDM2Q009873I2D: score=1 
    TP53P046373I2D: score=1 
    FLAD1ENSP000002921804STRING: ENSP00000292180
    PTGES3ENSP000002620334STRING: ENSP00000262033
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CA11 (CAH11)

    1 DrugBank Compound for CA11    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ZonisamideZonisamida [Spanish] (see all 2)68291-97-4targetinhibitor18537527 17762320 19703035 18782051 17582922

    1 Novoseek inferred chemical compound relationship for CA11 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    histidine 46.6 1 11311946 (1)



    Find genes that share compounds with CA11           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CA11 gene: 
    NM_001217.3  

    Unigene Cluster for CA11:

    Carbonic anhydrase XI
    Hs.428446  [show with all ESTs]
    Unigene Representative Sequence: NM_001217
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000084798(uc002pjz.1) ENST00000599267 ENST00000594088 ENST00000596080

    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate CA11:
    hsa-miR-633 hsa-miR-204 hsa-miR-211
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    GenScript: all cDNA clones in your preferred vector: CA11 (NM_001217)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA11
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    OriGene qSTAR qPCR primer pairs in human, mouse for CA11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CA11
      QuantiTect SYBR Green Assays in human, mouse, rat CA11
      QuantiFast Probe-based Assays in human, mouse, rat CA11

    Additional mRNA sequence: 

    AB018195.1 AF050106.1 AF067662.1 AY358967.1 BC002662.2 BT007265.1 CR541772.1 

    10 DOTS entries:

    DT.312205  DT.121440152  DT.91690588  DT.99932490  DT.121440146  DT.40109796  DT.91984130  DT.100832429 
    DT.91974646  DT.92423172 

    Selected AceView cDNA sequences (see all 97):

    BF205943 CK906061 BC002662 AA324885 AA297730 BQ639350 NM_001217 T34770 
    AI379560 AA297055 AI424443 BQ677430 AA378501 CB305582 AA297064 BQ884221 
    BI962646 BU733354 Z40177 BI789168 AI219818 AF067662 AY358967 BM548491 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CA11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCGCTGAGA
    CA11 Expression
    About this image


    CA11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Metencephalon
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Myoblasts Mandibular Arch Muscles
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
    CA11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CA11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.428446

    UniProtKB/Swiss-Prot: CAH11_HUMAN, O75493
    Tissue specificity: Expressed abundantly in the brain with moderate expression also present in spinal cord and
    thyroid

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CA11 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Car111 , 5 carbonic anhydrase 111, 5 90.24(n)1
    96.95(a)1
      7 (29.44 cM)5
    123481  NM_009800.41  NP_033930.11 
     456998435 
    lizard
    (Anolis carolinensis)
    Reptilia CA116
    carbonic anhydrase XI
    67(a)
    1 ↔ 1
    GL343279.1(1013841-1031491)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004938841 carbonic anhydrase-related protein 10-like 61.87(n)
    62.42(a)
      100493884  XM_002938122.2  XP_002938168.2 
    zebrafish
    (Danio rerio)
    Actinopterygii CA116
    carbonic anhydrase XI
    50(a)
    1 ↔ 1
    3(35005106-35066969) ENSDARG00000009568
    fruit fly
    (Drosophila melanogaster)
    Insecta CG326986
    CG14026
    --
    34(a)
    32(a)
    many ↔ many
    many ↔ many
    X(9682396-9743259)
    X(7720474-7734718)
    worm
    (Caenorhabditis elegans)
    Secernentea cah-23 Carbonic anhydrase 35(a)   II(7480790-7482468)   --


    ENSEMBL Gene Tree for CA11 (if available)
    TreeFam Gene Tree for CA11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CA11 gene
    CA102  
    8 SIMAP similar genes for CA11 using alignment to 2 protein entries:     CAH11_HUMAN (see all proteins):
    CA10    DKFZp686I20267    CA1    CA2    CA5A    CA7
    CA13    CA3

    Find genes that share paralogs with CA11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    3 SNPs for CA11    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs575902631,2
    C--45530844(+) AAAAA-/AGAAAG 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1892701071,2
    --45530905(+) CACACA/GCATCT 1 -- us2k10--------
    rs349530751,2
    ----45530827(+) ATCTC-/AAAAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CA11 (49141199 - 49149569 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CA11:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv3967n71CNV Loss21882294
    nsv912225CNV Loss21882294
    dgv3966n71CNV Loss21882294
    nsv9739CNV Gain+Loss18304495

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604644    OMIM disorders: --


    Find genes that share disorders with CA11           About GenesLikeMe


    Export disorders for CA11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CA11 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with CA11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related protein XI contains a sequence motif present in the neuropeptide sauvagine: the human CA-RP XI gene (CA11) is embedded between the secretor gene cluster and the DBP gene at 19q13.3. (PubMed id 9878252)1, 2, 3, 9 Lovejoy D.A.... Tashian R.E. (Genomics 1998)
    2. cDNA sequence, mRNA expression, and chromosomal localization of human carbonic anhydrase-related protein, CA-RP XI. (PubMed id 10350627)1, 2, 9 Fujikawa-Adachi K.... Onishi S. (Biochim. Biophys. Acta 1999)
    3. Sequence and tissue expression of a novel human carbonic anhydrase- related protein, CARP-2, mapping to chromosome 19q13.3. (PubMed id 9878543)1, 2, 9 Bellingham J.... Gregory-Evans C.Y. (Biochem. Biophys. Res. Commun. 1998)
    4. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (J. Proteome Res. 2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    7. cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain. (PubMed id 11311946)1, 9 Okamoto N.... Onishi S. (Biochim. Biophys. Acta 2001)
    8. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and I+ fetoprotein and their associations with cancer risk. (PubMed id 23300138)1 He M....Wu T. (Gut 2014)
    9. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (PubMed id 21926972)1 (Nat. Genet. 2011)
    10. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. (PubMed id 21060863)1 Ikram M.K....Wong T.Y. (PLoS Genet. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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    Free Text  

      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 770 HGNC: 1370 AceView: CA11 Ensembl:ENSG00000063180 euGenes: HUgn770
    ECgene: CA11 H-InvDB: CA11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CA11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CA11 gene:
    Search GeneIP for patents involving CA11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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