CA10 Gene

Aliases
for CA10 gene

Previous GC identifers: GC17U990008 GC17M052189 GC17M050049 GC17M050182 GC17M047062 GC17M045077

Summaries
for CA10 gene

Genomic Views
for CA10 gene

RefSeq DNA sequence:

NC_000017.10  NC_018928.1  NT_010783.15  

SwitchGear Promoter luciferase reporter plasmid: CA10 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CA10

CA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M049707:  view genomic region     (about GC identifiers)

Proteins
for CA10 gene

Explore the universe of human proteins at neXtProt for CA10: NX_Q9NS85

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	R&D Systems Recombinant & Natural Proteins for CA10 (Carbonic Anhydrase X/CA10)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Proteins (see all 3): CA10 OriGene Protein Over-expression Lysate (see all 5): CA10 OriGene Custom Protein Services for CA10
	GenScript Custom Purified and Recombinant Proteins Services for CA10
	Novus Biologicals CA10 Proteins Novus Biologicals CA10 Lysates
	Sino Biological Recombinant Protein for CA10
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CA10

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for CA10
	GenScript Custom Superior Antibodies Services for CA10
	Novus Biologicals CA10 Antibodies
	Search for Antibodies for CA10 at Abcam
	Uscn Antibodies for CA10
	Search ThermoFisher Antibodies for CA10

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CA10
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CA10

Protein Domains /
Families
for CA10 gene

ProtoNet protein and cluster: Q9NS85

Function
for CA10 gene

miRNA Products:		OriGene 3'-UTR Clone (see all 3): CA10 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CA10
		8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CA10 (see all 13):
		hsa-miR-30c hsa-miR-520d-5p hsa-miR-27a hsa-miR-128 hsa-miR-4306 hsa-miR-3681* hsa-miR-30d hsa-miR-30a
		SwitchGear 3'UTR luciferase reporter plasmid: CA10 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CA10 (see all 4) OriGene shRNA RFP: CA10 OriGene siRNA: CA10
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CA10

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for CA10

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CA10 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CA10 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CA10 (NM_080282)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CA10
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA10

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CA10
		Search LifeMap BioReagents cell lines for CA10

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA10

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

Pathways & Interactions
for CA10 gene

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

Drugs & Compounds
for CA10 gene

Transcripts
for CA10 gene

Expression
for CA10 gene

CA10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCCCTGTG

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	EyeInner Nuclear LayerType1 Off Cone Bipolar Cells			Bipolar, Retina
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Ventral/hypothalamic-like neurons (Generation of midbra...)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CA10 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CA10
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CA10
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CA10

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA10

Orthologs
for CA10 gene

Paralogs
for CA10 gene

Paralogs for CA10 gene

CA2²  CA12²  CA7²  CA6²  CA3²  CA11²  CA5B²  CA14²  

CA5A²  CA8²  CA4²  CA1²  CA13²  CA9²  

11 SIMAP similar genes for CA10 using alignment to 6 protein entries:     CAH10_HUMAN (see all proteins):

DKFZp686I20267    CA11    CA1    CA13    CA2    CA7

CA12    CA5A    CA3    CA5B    CA8

CA10 for paralogs           About GeneDecksing

Genomic Variants
for CA10 gene

10/9288 NCBI SNPs in CA10 are shown (see all 9288)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1914667691,2		--	49707203(+)	AATAGA/GTCTAG	3	--	ds5001		0	--	--	--	--
rs169501791,2	C,F,H,	--	49707251(+)	GATGCA/GAAAAG	3	--	ds5001		23		NA NS EA WA	2460
rs1483969691,2		--	49707328(+)	TTTTCA/GTTGTC	3	--	ds5001		0	--	--	--	--
rs733409011,2	C,F,	--	49707433(+)	GAGTGT/CGACAG	3	--	ds5001		4		WA NA	242
rs2001958621,2		--	49707475(+)	CACTG-/AACA           AACAA	3	--	ds5001		0	--	--	--	--
rs1450764931,2		--	49707517(+)	CTATAC/TGTTTT	3	--	ds5001		0	--	--	--	--
rs1501033811,2	C,	--	49707569(+)	AGGCT-/GGGTTCT	3	--	ds5001		0	--	--	--	--
rs37446631,2	C,F,H,	--	49707593(+)	GCCCCG/ATATGC	3	--	ds5001		24		NA NS EA WA CSA	2490
rs792814341,2	C	--	49707607(+)	TGCTCA/CTGCAC	3	--	ds5001		0	--	--	--	--
rs37446641,2	C,F,H,	--	49707608(+)	GCTCCT/AGCACC	3	--	ds5001		8		NS EA NA	662

HapMap Linkage Disequilibrium report for CA10 (49707674 - 49957674 bp, first 250kb of CA10)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for CA10
     4 CNVs: 67221 61576 102481 47874
     10 Indels: 88536 88532 77663 42936 77664 88531 88533 77665 88535 88534

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CA10

DNA2.0 Custom Variant and Variant Library Synthesis for CA10

Disorders / Diseases
for CA10 gene

Publications
for CA10 gene

PubMed articles for CA10 gene, integrated from 9 sources (see all 24): (articles sorted by number of sources associating them with CA10)

Utopia: connect your pdf to the dynamic world of online information

1. CCG repeats in cDNAs from human brain. (PubMed id 9921901)^{1, 2, 3} Kleiderlein J.J.... Margolis R.L. (1998)
2. cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain. (PubMed id 11311946)^{1, 2, 9} Okamoto N.... Onishi S. (2001)
3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
6. Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. (PubMed id 8673298)^{1, 3} Hewett-Emmett D. and Tashian R.E. (1996)
7. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
8. Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)¹ Elks C.E....Murray A. (2010)
9. Which carbonic anhydrases are targeted by the antiepi leptic sulfonamides and sulfamates? (PubMed id 19703035)⁷ De Simone G....Supuran C.T. (2009)
10. Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis. (PubMed id 19172221)¹ Mori S....Ikegawa S. (2009)

External Searches for CA10 gene

Genome Databases showing CA10 gene

Other Databases showing CA10 gene

Specialized Databases showing CA10 gene

Products
for CA10 gene