Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CA10 Gene

protein-coding   GIFtS: 53
GCID: GC17M049707

Carbonic Anhydrase X

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Carbonic Anhydrase X1 2     CARPX2 5
Carbonic Anhydrase-Related Protein X2 3     CA-RPX2
Cerebral Protein 152 3     HUCEP-152
CA-RP X2 3     Carbonic Anhydrase-Related Protein 102
CARP X2 3     Cerebral Protein-152

External Ids:    HGNC: 13691   Entrez Gene: 569342   Ensembl: ENSG000001549757   OMIM: 6046425   UniProtKB: Q9NS853   

Export aliases for CA10 gene to outside databases

Previous GC identifers: GC17U990008 GC17M052189 GC17M050049 GC17M050182 GC17M047062 GC17M045077


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CA10 Gene:
This gene encodes a protein that belongs to the carbonic anhydrase family of zinc metalloenzymes, which catalyze
the reversible hydration of carbon dioxide in various biological processes. The protein encoded by this gene is
an acatalytic member of the alpha-carbonic anhydrase subgroup, and it is thought to play a role in the central
nervous system, especially in brain development. Multiple transcript variants encoding the same protein have been
found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for CA10 Gene: 
CA10 (carbonic anhydrase X) is a protein-coding gene. Diseases associated with CA10 include periarthritis, and herpangina. GO annotations related to this gene include molecular_function. An important paralog of this gene is CA2.

UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
Function: Does not have a catalytic activity

Gene Wiki entry for CA10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010783.15  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CA10 gene promoter:
         Sox5   E2F-1   Pax-2   Egr-4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCA10 promoter sequence
   Search SABiosciences Chromatin IP Primers for CA10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q21.33   Ensembl cytogenetic band:  17q22   HGNC cytogenetic band: 17q21

CA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CA10 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M049707:  view genomic region     (about GC identifiers)

Start:
49,707,674 bp from pter      End:
50,237,377 bp from pter
Size:
529,704 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85 (See protein sequence)
Recommended Name: Carbonic anhydrase-related protein 10  
Size: 328 amino acids; 37563 Da
Developmental stage: Not expressed in fetal brain
Secondary accessions: B2R7J0

Explore the universe of human proteins at neXtProt for CA10: NX_Q9NS85

Explore proteomics data for CA10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NS85

  • CA10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CA10 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001076002.1  NP_001076003.1  NP_064563.1  

    ENSEMBL proteins: 
     ENSP00000459619   ENSP00000390666   ENSP00000461908   ENSP00000405388   ENSP00000285273  
     ENSP00000460238   ENSP00000458145   ENSP00000340363  

    Human Recombinant Protein Products for CA10: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for CA10 (Carbonic Anhydrase X/CA10)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Proteins for CA10
    OriGene Protein Over-expression Lysate for CA10
    OriGene MassSpec for CA10 
    OriGene Custom Protein Services for CA10
    GenScript Custom Purified and Recombinant Proteins Services for CA10
    Novus Biologicals CA10 Proteins
    Novus Biologicals CA10 Lysates
    Sino Biological Recombinant Protein for CA10
    Sino Biological Cell Lysate for CA10 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CA10 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    CA10 for ontologies           About GeneDecksing



    CA10 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CA10 (Carbonic Anhydrase X/CA10)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CA10
    GenScript Custom Superior Antibodies Services for CA10
    Novus Biologicals CA10 Antibodies
    Abcam antibodies for CA10
    Cloud-Clone Corp. Antibodies for CA10 
    Search ThermoFisher Antibodies for CA10
    LSBio Antibodies in human, mouse, rat for CA10 

    Assay Products for CA10: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CA10
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CA10
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CA10 
    Cloud-Clone Corp. CLIAs for CA10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CA: Carbonic anhydrases

    3 InterPro protein domains:
     IPR001148 Carbonic_anhydrase_a
     IPR023561 Carbonic_anhydrase_a-class
     IPR018423 Carbonic_anhydrase-RP_CA10

    Graphical View of Domain Structure for InterPro Entry Q9NS85

    ProtoNet protein and cluster: Q9NS85

    1 Blocks protein domain: IPB001148 Carbonic anhydrase

    UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
    Similarity: Belongs to the alpha-carbonic anhydrase family


    CA10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CAH10_HUMAN, Q9NS85
    Function: Does not have a catalytic activity

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    CA10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CA10:
     Decreased cell number  Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CA10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CA10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CA10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CA10 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CA10
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CA10 (see all 13):
    hsa-miR-30c hsa-miR-520d-5p hsa-miR-27a hsa-miR-128 hsa-miR-4306 hsa-miR-3681* hsa-miR-30d hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidCA10 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CA10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CA10
    Sirion Biotech Customized adenovirus for overexpression of CA10

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CA10 (see all 19)
    OriGene ORF clones in mouse, rat for CA10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CA10 (NM_080282)
    Sino Biological Human cDNA Clone for CA10
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA10
    Sirion Biotech Customized lentivirus for stable overexpression of CA10 
                         Customized lentivirus expression plasmids for stable overexpression of CA10 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CA10
    Search LifeMap BioReagents cell lines for CA10
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CA10

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007420brain development NAS11311946

    CA10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CA10 (CAH10)

    1 DrugBank Compound for CA10    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    ZonisamideZonisamida [Spanish] (see all 2)68291-97-4targetinhibitor18537527 17762320 19703035 18782051 17582922

    Search CenterWatch for drugs/clinical trials and news about CA10 / CAH10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CA10 gene (3 alternative transcripts): 
    NM_001082533.1  NM_001082534.1  NM_020178.4  

    Unigene Cluster for CA10:

    Carbonic anhydrase X
    Hs.463466  [show with all ESTs]
    Unigene Representative Sequence: NM_001082533
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570565 ENST00000442502(uc002itv.4 uc002ity.4 uc002itz.2)
    ENST00000571371 ENST00000451037(uc002itw.4) ENST00000285273(uc002itx.4)
    ENST00000575181 ENST00000571918 ENST00000575097 ENST00000573294 ENST00000340813

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CA10
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate CA10 (see all 13):
    hsa-miR-30c hsa-miR-520d-5p hsa-miR-27a hsa-miR-128 hsa-miR-4306 hsa-miR-3681* hsa-miR-30d hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmidCA10 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CA10
    Clone
    Products:
         
    OriGene clones in human, mouse for CA10 (see all 19)
    OriGene ORF clones in mouse, rat for CA10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CA10 (NM_080282)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA10
    Sirion Biotech Customized lentivirus for stable overexpression of CA10 
                         Customized lentivirus expression plasmids for stable overexpression of CA10 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CA10
    OriGene qSTAR qPCR primer pairs in human, mouse for CA10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CA10
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CA10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CA10

    Additional mRNA sequence: 

    AB001597.1 AB036836.1 AF288385.1 AK294652.1 AK313001.1 AL161812.1 AY358509.1 BC020577.1 
    BC029865.1 BC047456.1 BC068462.1 CR749607.1 

    8 DOTS entries:

    DT.97816776  DT.97784104  DT.92041233  DT.446487  DT.100837832  DT.75114486  DT.92418770  DT.120993495 

    24/98 AceView cDNA sequences (see all 98):

    BX281234 BC047456 AY358509 AI470807 AI815617 AF288385 AA709457 AA063170 
    CR749607 T30964 CR609088 F06106 AA716317 BM703408 AA723288 BM723566 
    AI074499 F05437 BF934583 F11600 AI338414 Z41624 H10857 Z40949 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CA10 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                                        -     -                                             
    SP2:                                                                                                            
    SP3:                                                              -                                             
    SP4:              -     -                                                                                       
    SP5:              -     -                                                                                       


    ECgene alternative splicing isoforms for CA10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CA10 expression in normal human tissues (normalized intensities)      CA10 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCCCTGTG
    CA10 Expression
    About this image


    CA10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/11 selected tissues (see all 11) fully expand
     
     Brain (Nervous System)    fully expand to see all 11 entries
             Oligodendrocyte Precursor Cells Forebrain White Matter
             Thalamus
             cerebellum   
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             Metencephalon
     
     Limb (Muscoskeletal System)    fully expand to see all 2 entries
             limb/hindlimb   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   

    See CA10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CA10

    SOURCE GeneReport for Unigene cluster: Hs.463466

    UniProtKB/Swiss-Prot: CAH10_HUMAN, Q9NS85
    Tissue specificity: Strong expression in brain and central nervous system

        SABiosciences Custom PCR Arrays for CA10
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CA10
    OriGene qSTAR qPCR primer pairs in human, mouse for CA10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CA10
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CA10
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CA10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CA10 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Car101 , 5 carbonic anhydrase 101, 5 94.51(n)1
    100(a)1
      11 (58.43 cM)5
    726051  NM_028296.31  NP_082572.11 
     930980285 
    chicken
    (Gallus gallus)
    Aves CA101 carbonic anhydrase X 86.79(n)
    99.39(a)
      417389  XM_415644.3  XP_415644.1 
    lizard
    (Anolis carolinensis)
    Reptilia CA106
    Uncharacterized protein
    99(a)
    1 ↔ 1
    2(90183325-90558440)
    zebrafish
    (Danio rerio)
    Actinopterygii wufd54f062 Transcribed sequence with moderate similarity to protein more 79.26(n)    AL915399.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG326981 CG32698 53.5(n)
    43.71(a)
      31915  NM_132353.3  NP_572581.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cah-21 Protein CAH-2 47.37(n)
    38.83(a)
      174218  NM_063166.5  NP_495567.3 


    ENSEMBL Gene Tree for CA10 (if available)
    TreeFam Gene Tree for CA10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CA10 gene
    CA22  CA122  CA72  CA32  CA62  CA112  CA5B2  CA5A2  
    CA142  CA82  CA42  CA12  CA92  CA132  
    11 SIMAP similar genes for CA10 using alignment to 6 protein entries:     CAH10_HUMAN (see all proteins):
    DKFZp686I20267    CA11    CA1    CA13    CA2    CA7
    CA12    CA5A    CA3    CA5B    CA8

    CA10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/10634 SNPs in CA10 are shown (see all 10634)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs357970911,2
    C--45377243(+) TTTGT-/CTGTTTT 3 -- int11Minor allele frequency- CT:0.00NA 2
    rs1914667691,2
    --49707203(+) AATAGA/GTCTAG 3 -- ds50010--------
    rs169501791,2
    C,F,H--49707251(+) GATGCA/GAAAAG 3 -- ds500123Minor allele frequency- G:0.04NA NS EA WA 2460
    rs1483969691,2
    --49707328(+) TTTTCA/GTTGTC 3 -- ds50010--------
    rs733409011,2
    C,F--49707433(+) GAGTGT/CGACAG 3 -- ds50014Minor allele frequency- C:0.06WA NA 242
    rs2001958621,2
    --49707475(+) CACTG-/AACA  
            
    AACAA
    3 -- ds50010--------
    rs1450764931,2
    --49707517(+) CTATAC/TGTTTT 3 -- ds50010--------
    rs1501033811,2
    C--49707569(+) AGGCT-/GGGTTCT 3 -- ds50010--------
    rs37446631,2
    C,F,H--49707593(+) GCCCCG/ATATGC 3 -- ds500124Minor allele frequency- A:0.26NA NS EA WA CSA 2490
    rs792814341,2
    C--49707607(+) TGCTCA/CTGCAC 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for CA10 (49707674 - 49957674 bp, first 250kb of CA10)

    Structural Variations
         Database of Genomic Variants (DGV) 10/20 variations for CA10 (see all 20):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716047CNV Deletion23290073
    dgv554e199CNV Deletion23128226
    esv4530CNV Deletion18987735
    esv2716046CNV Deletion23290073
    esv2670652CNV Deletion23128226
    esv2673970CNV Deletion23128226
    nsv507844CNV Insertion20534489
    esv270984CNV Insertion20981092
    esv273536CNV Insertion20981092
    esv2567906CNV Insertion19546169

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CA10
    DNA2.0 Custom Variant and Variant Library Synthesis for CA10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604642    OMIM disorders: --

    8 diseases for CA10:    About MalaCards
    periarthritis    herpangina    retrograde amnesia    mouth disease
    cerebritis    aseptic meningitis    chondroblastoma    meningitis

    3 diseases from the University of Copenhagen DISEASES database for CA10:
    hand, foot and mouth disease     Retrograde amnesia     Herpangina

    CA10 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CA10
    Human Genome Epidemiology (HuGE) Navigator: CA10 (5 documents)

    Export disorders for CA10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CA10 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with CA10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CCG repeats in cDNAs from human brain. (PubMed id 9921901)1, 2, 3 Kleiderlein J.J.... Margolis R.L. (1998)
    2. cDNA sequence of human carbonic anhydrase-related protein, CA-RP X: mRNA expressions of CA-RP X and XI in human brain. (PubMed id 11311946)1, 2, 9 Okamoto N.... Onishi S. (2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. Thirty new loci for age at menarche identified by a m eta-analysis of genome-wide association studies. (PubMed id 21102462)1, 4 Elks C.E....Murray A. (2010)
    5. Nucleotide variations in genes encoding carbonic anhydrase 8 and 10 associated with femoral bone mineral density in Japanese female with osteoporosis. (PubMed id 19172221)1, 4 Mori S....Ikegawa S. (2009)
    6. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    9. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    10. Functional diversity, conservation, and convergence in the evolution of the alpha-, beta-, and gamma-carbonic anhydrase gene families. (PubMed id 8673298)1, 3 Hewett-Emmett D. and Tashian R.E. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56934 HGNC: 1369 AceView: CA10 Ensembl:ENSG00000154975 euGenes: HUgn56934
    ECgene: CA10 H-InvDB: CA10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CA10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CA10 gene:
    Search GeneIP for patents involving CA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for CA10 (Carbonic Anhydrase X/CA10)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Recombinant/Natural Proteins for CA10 (Carbonic Anhydrase X/CA10)  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CA10  
     OriGene qPCR primer pairs and template standards for CA10   OriGene Protein Over-expression Lysate for CA10  
     OriGene MassSpec something-or-other for CA10   OriGene clones in human, mouse for CA10  
     OriGene qSTAR qPCR primer pairs in human, mouse for CA10   OriGene Purified Protein for CA10  
     OriGene ORF clones in mouse, rat for CA10   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CA10   OriGene Custom Protein Services for CA10  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CA10
     QIAGEN SeqTarget long-range PCR primers for resequencing CA10
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CA10
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CA10
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CA10
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CA10
     GenScript Custom Purified and Recombinant Proteins Services for CA10 GenScript cDNA clones with any tag delivered in your preferred vector for CA10
     GenScript Custom Assay Services for CA10 GenScript Custom Superior Antibodies Services for CA10
     GenScript Custom overexpressing Cell Line Services for CA10 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CA10 promoter
     Search Chromatin IP Primers for CA10
     RT2 qPCR Primer Assay in human, mouse, rat CA10
     Search GNC Networks for CA10
     SABiosciences Custom PCR Arrays for CA10
     Search Tocris compounds for CA10 (CAH10)
     Proteins and Antibodies for CA10
     Cell Lysates for CA10
     cDNA Clones for CA10
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CA10 antibodies
     CA10 proteins
     CA10 lysates
     Antibodies for CA10
     See all of Abcam's Antibodies, Kits and Proteins for CA10
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for CA10
     Antibodies for CA10
     ELISAs for CA10
     CLIAs for CA10
     Search LifeMap BioReagents cell lines for CA10
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CA10
     SwitchGear 3'UTR luciferase reporter plasmids for CA10
     SwitchGear Promoter luciferase reporter plasmids for CA10
     Search ThermoFisher Antibodies for CA10
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CA10
     inGenious Targeting Laboratory - Custom generated mouse model solutions for CA10
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CA10
    Customized:
     lentivirus for stable overexpression of CA10
     lentivirus expression plasmids for stable overexpression of CA10
     adenovirus for overexpression of CA10
     LSBio Antibodies in human, mouse, rat for CA10
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CA10 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4