Aliases for CA1 Gene
External Ids for CA1 Gene
Previous GeneCards Identifiers for CA1 Gene
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
GeneCards Summary for CA1 Gene
CA1 (Carbonic Anhydrase 1) is a Protein Coding gene. Diseases associated with CA1 include occlusion precerebral artery and intracranial abscess. Among its related pathways are Nitrogen metabolism and O2/CO2 exchange in erythrocytes. GO annotations related to this gene include carbonate dehydratase activity and hydro-lyase activity. An important paralog of this gene is CA14.
UniProtKB/Swiss-Prot for CA1 Gene
Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.