Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C9orf92 Gene

Aliases for C9orf92 Gene

  • Chromosome 9 Open Reading Frame 92 2 3 5
  • Putative Uncharacterized Protein C9orf92 3
  • Em:AL513424.1 3

External Ids for C9orf92 Gene

Previous GeneCards Identifiers for C9orf92 Gene

  • GC09U900592

Summaries for C9orf92 Gene

GeneCards Summary for C9orf92 Gene

C9orf92 (Chromosome 9 Open Reading Frame 92) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf92 Gene

Genomics for C9orf92 Gene

Regulatory Elements for C9orf92 Gene

Enhancers for C9orf92 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F016304 0.4 ENCODE 11.9 -28.2 -28175 0.2 C9orf92 GC09P016278 GC09P016344
GH09F016305 0.2 ENCODE 11.9 -27.9 -27905 0.2 C9orf92 GC09P016278 GC09P016344
GH09F016252 0.4 ENCODE 11.9 +23.5 23536 0.2 TEAD4 MAFK C9orf92 GC09P016216
GH09F016308 0.9 Ensembl ENCODE 11.9 -33.6 -33629 2.7 C9orf92 CNTLN GC09P016278 GC09P016344
GH09F016314 0.5 ENCODE 11.7 -39.8 -39784 3.3 ATF3 RAD21 YY1 C9orf92 SNAPC3 GC09P016344 GC09P016278
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C9orf92 on UCSC Golden Path with GeneCards custom track

Genomic Location for C9orf92 Gene

16,203,935 bp from pter
16,276,313 bp from pter
72,379 bases
Minus strand

Genomic View for C9orf92 Gene

Genes around C9orf92 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf92 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf92 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf92 Gene

Proteins for C9orf92 Gene

  • Protein details for C9orf92 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein C9orf92
    Protein Accession:
    Secondary Accessions:
    • A6NMF8

    Protein attributes for C9orf92 Gene

    77 amino acids
    Molecular mass:
    8520 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C9orf92 Gene


neXtProt entry for C9orf92 Gene

Post-translational modifications for C9orf92 Gene

No Post-translational modifications

Other Protein References for C9orf92 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C9orf92 Gene

Domains & Families for C9orf92 Gene

Protein Domains for C9orf92 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf92: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf92 Gene

Function for C9orf92 Gene

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C9orf92 Gene

Localization for C9orf92 Gene

Subcellular locations from

Jensen Localization Image for C9orf92 Gene COMPARTMENTS Subcellular localization image for C9orf92 gene
Compartment Confidence
cytosol 2
extracellular 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C9orf92 Gene

Pathways & Interactions for C9orf92 Gene

SuperPathways for C9orf92 Gene

No Data Available

Interacting Proteins for C9orf92 Gene

Gene Ontology (GO) - Biological Process for C9orf92 Gene


No data available for Pathways by source and SIGNOR curated interactions for C9orf92 Gene

Transcripts for C9orf92 Gene

mRNA/cDNA for C9orf92 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf92 Gene

Chromosome 9 open reading frame 92:
Representative Sequences:

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf92 Gene

No ASD Table

Relevant External Links for C9orf92 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf92 Gene

mRNA expression in normal human tissues for C9orf92 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf92 Gene

This gene is overexpressed in Prostate (x7.8).

NURSA nuclear receptor signaling pathways regulating expression of C9orf92 Gene:


SOURCE GeneReport for Unigene cluster for C9orf92 Gene:

genes like me logo Genes that share expression patterns with C9orf92: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C9orf92 Gene

Orthologs for C9orf92 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C9orf92 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC465004 34
  • 98.15 (n)
C9orf92 35
  • 97 (a)
Species where no ortholog for C9orf92 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf92 Gene

Gene Tree for C9orf92 (if available)
Gene Tree for C9orf92 (if available)

Paralogs for C9orf92 Gene

No data available for Paralogs for C9orf92 Gene

Variants for C9orf92 Gene

Sequence variations from dbSNP and Humsavar for C9orf92 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1010634 -- 16,247,126(+) ttttc(C/T)ctgtg intron-variant
rs10118247 -- 16,211,086(+) CTGAT(C/G)CTTTT intron-variant
rs10118271 -- 16,211,137(+) AGTTT(C/T)ATATC intron-variant
rs10119177 -- 16,212,181(+) CTTTA(C/G)TCCCT intron-variant
rs10121254 -- 16,239,570(+) CAATT(A/G)TGCTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf92 Gene

Variant ID Type Subtype PubMed ID
esv3619808 CNV loss 21293372
nsv520183 CNV loss 19592680
nsv523890 CNV loss 19592680
nsv6490 CNV insertion 18451855

Variation tolerance for C9orf92 Gene

Gene Damage Index Score: 2.82; 47.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C9orf92 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf92 Gene

Disorders for C9orf92 Gene

Relevant External Links for C9orf92

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C9orf92 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf92 Gene

Publications for C9orf92 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington J.J. … Ducar M. (Nat. Biotechnol. 2001) 3 4 64
  3. Fusion of the HMGA2 and C9orf92 genes in myolipoma with t(9;12)(p22;q14). (PMID: 26857357) Panagopoulos I. … Heim S. (Diagn Pathol 2016) 3 64

Products for C9orf92 Gene

Sources for C9orf92 Gene

Loading form....