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Aliases for C9orf57 Gene

Aliases for C9orf57 Gene

  • Chromosome 9 Open Reading Frame 57 2 3

External Ids for C9orf57 Gene

Previous GeneCards Identifiers for C9orf57 Gene

  • GC09M070123
  • GC09M070113
  • GC09M071895
  • GC09M073856
  • GC09M074666
  • GC09M044488

Summaries for C9orf57 Gene

GeneCards Summary for C9orf57 Gene

C9orf57 (Chromosome 9 Open Reading Frame 57) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf57 Gene

Genomics for C9orf57 Gene

Regulatory Elements for C9orf57 Gene

Genomic Location for C9orf57 Gene

72,051,376 bp from pter
72,072,721 bp from pter
21,346 bases
Minus strand

Genomic View for C9orf57 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C9orf57 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf57 Gene

Proteins for C9orf57 Gene

  • Protein details for C9orf57 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C9orf57
    Protein Accession:
    Secondary Accessions:
    • A1L456

    Protein attributes for C9orf57 Gene

    161 amino acids
    Molecular mass:
    18115 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C9orf57 Gene


neXtProt entry for C9orf57 Gene

Proteomics data for C9orf57 Gene at MOPED

Post-translational modifications for C9orf57 Gene

No Post-translational modifications

Other Protein References for C9orf57 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for C9orf57 Gene

Domains for C9orf57 Gene

Protein Domains for C9orf57 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf57: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf57 Gene

Function for C9orf57 Gene

Phenotypes for C9orf57 Gene

GenomeRNAi human phenotypes for C9orf57:
genes like me logo Genes that share phenotypes with C9orf57: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf57

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C9orf57 Gene

Localization for C9orf57 Gene

Subcellular locations from UniProtKB/Swiss-Prot for C9orf57 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for C9orf57 Gene COMPARTMENTS Subcellular localization image for C9orf57 gene
Compartment Confidence
plasma membrane 3
cytosol 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for C9orf57 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with C9orf57: view

Pathways for C9orf57 Gene

SuperPathways for C9orf57 Gene

No Data Available

Interacting Proteins for C9orf57 Gene

Gene Ontology (GO) - Biological Process for C9orf57 Gene


No data available for Pathways by source for C9orf57 Gene

Transcripts for C9orf57 Gene

mRNA/cDNA for C9orf57 Gene

(5) Additional mRNA sequences :
(2) REFSEQ mRNAs :
(12) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf57 Gene

Chromosome 9 open reading frame 57:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf57

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf57 Gene

No ASD Table

Relevant External Links for C9orf57 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf57 Gene

mRNA expression in normal human tissues for C9orf57 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf57 Gene

This gene is overexpressed in Testis (51.1).

SOURCE GeneReport for Unigene cluster for C9orf57 Gene Hs.371235

genes like me logo Genes that share expressions with C9orf57: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for C9orf57 Gene

Orthologs for C9orf57 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C9orf57 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia C9orf57 36
  • 59 (a)
(Mus musculus)
Mammalia Gm3443 36
  • 59 (a)
(Pan troglodytes)
Mammalia C9orf57 36
  • 98 (a)
Species with no ortholog for C9orf57:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf57 Gene

Gene Tree for C9orf57 (if available)
Gene Tree for C9orf57 (if available)

Paralogs for C9orf57 Gene

No data available for Paralogs for C9orf57 Gene

Variants for C9orf57 Gene

Sequence variations from dbSNP and Humsavar for C9orf57 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1010121 -- 72,055,451(-) tgaga(C/T)catgt intron-variant
rs1570638 -- 72,052,854(+) GGAGG(C/T)GTATG intron-variant
rs1570639 -- 72,053,196(+) GGTAA(A/C)AGCTA intron-variant
rs3192907 -- 72,051,480(-) GAAGA(A/G)TACTG utr-variant-3-prime
rs3858112 -- 72,055,686(-) ATGCC(C/T)GTGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf57 Gene

Variant ID Type Subtype PubMed ID
nsv831618 CNV Loss 17160897
nsv893445 CNV Gain 21882294
esv22526 CNV Gain 19812545
esv2667732 CNV Deletion 23128226

Relevant External Links for C9orf57 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf57 Gene

Disorders for C9orf57 Gene

No disorders were found for C9orf57 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C9orf57 Gene

Publications for C9orf57 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3

Products for C9orf57 Gene

Sources for C9orf57 Gene

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