C9orf3 Gene
protein-coding GIFtS: 49
GCID: GC09P097488
|
|
chromosome 9 open reading frame 3
| |
Aliases
for C9orf3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 9 Open Reading Frame 31 2 | | ONPEP2 3 | | AP-O1 2 3 | | FLJ146751 | | AOPEP1 2 | | Aminopeptidase O2 | | APO1 2 | | EC 3.4.11.-3 | | C90RF31 2 | | |
Export aliases for C9orf3 gene to outside databasesPrevious GC identifers: GC09U990106 GC09P092831 GC09P094568 GC09P096528 |
Summaries
for C9orf3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for C9orf3:
This gene encodes a member of the M1 zinc aminopeptidase family. The encoded protein is a zinc-dependentmetallopeptidase that catalyzes the removal of an amino acid from the amino terminus of a protein or peptide. Thisprotein may play a role in the generation of angiotensin IV. Alternate splicing results in multiple transcriptvariants. (provided by RefSeq, Oct 2010)
UniProtKB/Swiss-Prot: AMPO_HUMAN, Q8N6M6Function: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or proteinsubstrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensinpathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing ofbioactive peptides in tissues such as testis and heart
|
Genomic Views
for C9orf3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C9orf3 gene promoter:
HNF-4alpha2 HNF-4alpha1 Pax-3 PPAR-gamma1 POU2F1 POU2F1a HFH-1 Zic3 Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for C9orf3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C9orf3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q22.32 Ensembl cytogenetic band: 9q22.32 HGNC cytogenetic band: 9q22C9orf3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P097488: view genomic region
(about GC identifiers)
Start:
|
97,488,886 bp from pter |
End:
|
97,849,500 bp from pter |
Size:
|
360,615 bases |
Orientation:
|
plus strand |
|
Proteins
for C9orf3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: AMPO_HUMAN, Q8N6M6 (See
protein sequence)Recommended Name: Aminopeptidase O Size: 819 amino acids; 93572 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Subcellular location: Cytoplasm (Potential)
Sequence caution: Sequence=AAH20194.1; Type=Erroneous initiation; Sequence=BAB55210.1; Type=Erroneous initiation;
Secondary accessions: Q5T9B1 Q5T9B3 Q5T9B4 Q8WUL6 Q96M23 Q96SS1Alternative splicing: 4 isoforms: Q8N6M6-1 Q8N6M6-2 Q8N6M6-3 Q8N6M6-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for C9orf3: NX_Q8N6M6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N6M6
C9orf3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001180258.1 NP_001180260.1 NP_116212.3
ENSEMBL proteins: ENSP00000277198 ENSP00000297979 ENSP00000387736 ENSP00000402171 ENSP00000401854 ENSP00000411451 ENSP00000413927 ENSP00000431923 ENSP00000364464 ENSP00000378763 ENSP00000411815 ENSP00000399365
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
C9orf3 for ontologies About GeneDecksing
C9orf3 Antibody Products:
Assay Products for C9orf3: |
Protein
Domains /
Families
for C9orf3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
C9orf3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N6M6ProtoNet protein and cluster: Q8N6M6 1 Blocks protein family: IPB001930 Membrane alanyl dipeptidase (M1) family signature
UniProtKB/Swiss-Prot: AMPO_HUMAN, Q8N6M6Similarity: Belongs to the peptidase M1 family |
Function
for C9orf3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: AMPO_HUMAN, Q8N6M6Function: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or proteinsubstrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensinpathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing ofbioactive peptides in tissues such as testis and heartEnzyme regulation: Strongly inhibited by ophenanthroline, a metalloprotease inhibitor. Inhibited by arphamenine A, apotent inhibitor of aminopeptidases. Not affected by AEBSF and E-64, which are common inhibitors of serine- andcysteine-proteases, respectivelyBiophysicochemical properties: Kinetic parameters: KM=6 uM for Asn-AMC;Enzyme Number (IUBMB): EC 3.4.11.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for C9orf3 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C9orf3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf3 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
C9orf3 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for C9orf3:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for 2010111I01Rik):
C9orf3 for phenotypes About GeneDecksing
|
Pathways & Interactions
for C9orf3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C9orf3
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C9orf3 (ENSP000002979794) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
C9orf3 for ontologies About GeneDecksing
|
Drugs & Compounds
for C9orf3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
C9orf3 for compounds About GeneDecksing
 Browse Tocris compounds for C9orf3
1 Novoseek chemical compound relationship for C9orf3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| calcium |
0.78 |
1 |
1331470 (1) |
Search CenterWatch for drugs/clinical trials and news about C9orf3 / AMPO
|
Transcripts
for C9orf3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C9orf3 gene (4 alternative transcripts): NM_001193329.1 NM_001193331.2 NM_032823.5 NM_001193330.1 Unigene Cluster for C9orf3: Chromosome 9 open reading frame 3 Hs.434253 [show with all ESTs]Unigene Representative Sequence: NM_00119333118/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25): ENST00000277198(uc011lui.2) ENST00000297979(uc004auz.1 uc004auy.3)
ENST00000427193 ENST00000489318 ENST00000424143 ENST00000428313 ENST00000488186
ENST00000473778(uc004aux.2 uc004avb.2) ENST00000462125 ENST00000479161
ENST00000451893 ENST00000460573 ENST00000478603 ENST00000471978 ENST00000445181
ENST00000478473 ENST00000496567 ENST00000463372
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for C9orf3 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C9orf3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf3 |
Additional cDNA sequence: AJ560639.1 AK027581.1 AK057450.1 AK098242.1 AK300486.1 AL137535.1 BC020194.1 BC029616.1 BX648970.1 XR_108980.3 XR_113239.3 XR_171798.1 24/37 DOTS entries (see all 37): DT.40248026 DT.100756509 DT.100027770 DT.416755 DT.121205361 DT.311933 DT.86843432 DT.40297749 DT.100756511 DT.121205280 DT.40257308 DT.100756507 DT.40189138 DT.435162 DT.92031635 DT.97845123 DT.95189992 DT.110871 DT.86839700 DT.100840792 DT.110872 DT.121205441 DT.100845153 DT.121205306 24/314 AceView cDNA sequences (see all 314): BM709075 AA243805 CK821156 CA421709 BQ439422 H02989 CR626738 CR626537 CK818950 AK057450 BX398348 BM126351 CR592311 BU621588 AA889182 AK027581 BC029616 AW292077 BU624536 BI826009 BM783016 AW662567 BF969144 AL711395
GeneLoc Exon Structure
5/28 Alternative Splicing Database (ASD) splice patterns (SP) for C9orf3 (see all 28) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | - | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | |
| ExUns: | 21a | · | 21b | · | 21c | · | 21d | · | 21e | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · | 24b | ^ | 25 | ^ | 26 | ^ | 27a | · | 27b | · | 27c | · | 27d | · | 27e | · | 27f | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | · | 31c | ^ | 32a | · | 32b | · |
|---|
|
| SP1: | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | |
| SP2: | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | |
| SP3: | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | |
| SP4: | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | | |
| SP5: | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | - | | | | | |
| ExUns: | 32c | ^ | 33 | ^ | 34a | · | 34b | · | 34c | · | 34d | ^ | 35 | ^ | 36a | · | 36b | · | 36c | · | 36d | · | 36e |
|---|
|
| SP1: | - | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP2: | - | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP3: | - | | - | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for C9orf3
|
Expression
for C9orf3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C9orf3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGGATGCG
About this image
See C9orf3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C9orf3
SOURCE GeneReport for Unigene cluster: Hs.434253
UniProtKB/Swiss-Prot: AMPO_HUMAN, Q8N6M6Tissue specificity: Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level inbrain, lung and kidney
SABiosciences Custom PCR Arrays for C9orf3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C9orf3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C9orf3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C9orf3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C9orf3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf3 |
Orthologs
for C9orf3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for C9orf3 gene from 9/26 species (see all 26) About this table
ENSEMBL Gene Tree for C9orf3 (if available)
TreeFam Gene Tree for C9orf3 (if available) |
Paralogs
for C9orf3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for C9orf3 gene
- LTA4H2 RNPEPL12 RNPEP2
1 SIMAP similar gene for C9orf3 using alignment to 6 protein entries: B4DKT1_HUMAN (see all proteins):AOPEP
C9orf3 for paralogs About GeneDecksing
|
Genomic Variants
for C9orf3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for C9orf3 (97488886 - 97738886 bp, first 250kb of C9orf3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for C9orf3
2 Indels: 60760 60759 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C9orf3 |
|
Disorders
/ Diseases
for C9orf3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C9orf3 for disorders About GeneDecksing
5  diseases for C9orf3: About MalaCardsnewborn respiratory distress syndrome root resorption prostate cancer prostatitis
malaria
1 disease from the University of Copenhagen DISEASES database for C9orf3:Newborn respiratory distress syndrome Human Genome Epidemiology (HuGE) Navigator: C9orf3 (1 document)
Export disorders for C9orf3 gene to outside databases
|
Publications
for C9orf3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C9orf3 gene, integrated from 9 sources (see all 19):
(articles sorted by number of sources associating them with C9orf3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase. (PubMed id 15687497)1, 2, 9 Diaz-Perales A.... Lopez-Otin C. (2005)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Meta-analysis identifies six new susceptibility loci f or atrial fibrillation. (PubMed id 22544366)1 Ellinor P.T....Kaab S. (2012)
- Genome-wide association study identifies eight new ris k loci for polycystic ovary syndrome. (PubMed id 22885925)1 Shi Y....Chen Z.J. (2012)
- LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins. (PubMed id 22632968)1 Sosa B.A....Schwartz T.U. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genome-wide association study to identify single nucl eotide polymorphisms (SNPs) associated with the development of erectile dysfunc tion in African-American men after radiotherapy for prostate cancer. (PubMed id 20932654)1 Kerns S.L....Rosenstein B.S. (2010)
|
External Searches for C9orf3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C9orf3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C9orf3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C9orf3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C9orf3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C9orf3 gene:
Search GeneIP for patents involving C9orf3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for C9orf3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C9orf3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C9orf3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C9orf3 | | | OriGene Protein Over-expression Lysate for C9orf3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C9orf3 | | OriGene 3'-UTR Clone for C9orf3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for C9orf3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C9orf3 | | OriGene Custom Protein Services for C9orf3 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C9orf3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C9orf3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C9orf3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C9orf3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C9orf3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C9orf3 |
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| | | | Search Tocris compounds for C9orf3 |
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 | | | C9orf3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf3 |
|  |  |  | | | | Search ThermoFisher Antibodies for C9orf3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf3 |
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