Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

C9orf24 Gene

protein-coding   GIFtS: 45
GCID: GC09M034334

chromosome 9 open reading frame 24
 Explore 2 diseases affiliated with
C9orf24 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for C9orf24    

Aliases
for C9orf24 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Chromosome 9 Open Reading Frame 241 2     Testis Development Protein NYD-SP222 3
CBE11 2 3     MGC329211
NYD-SP221 2     MGC336141
SMRP11 2     Ciliated Bronchial Epithelium 12
BA573M23.41     Spermatid-Specific Manchette-Related Protein 12
Ciliated Bronchial Epithelial Protein 12 3     

External Ids:    HGNC: 199191   Entrez Gene: 846882   Ensembl: ENSG000001649727   UniProtKB: Q8NCR63   

Export aliases for C9orf24 gene to outside databases

Previous GC identifers: GC09M034548 GC09M034369


Summaries
for C9orf24 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for C9orf24:
This gene encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known
proteins. Expression of this gene is induced during the differentiation of bronchial epithelial cells, and the encoded
protein may play a role in ciliogenesis. Alternatively spliced transcript variants encoding multiple isoforms have
been observed for this gene. (provided by RefSeq, Nov 2011)

UniProtKB/Swiss-Prot: SMRP1_HUMAN, Q8NCR6
Function: May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of
ciliated cells




Genomic Views
for C9orf24 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008413.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the C9orf24 gene promoter:
         AhR   USF1   USF2   STAT5A   USF-1:USF-2   YY1   Arnt   N-Myc   USF-1   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for C9orf24

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C9orf24


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9p13.3   Ensembl cytogenetic band:  9p13.3   HGNC cytogenetic band: 9p11.2

C9orf24 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
C9orf24 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M034334:  view genomic region     (about GC identifiers)

Start:
 34,379,017 bp from pter      End:
 34,397,849 bp from pter
Size:
 18,833 bases      Orientation:
 minus strand

Proteins
for C9orf24 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: SMRP1_HUMAN, Q8NCR6 (See protein sequence)
Recommended Name: Spermatid-specific manchette-related protein 1  
Size: 262 amino acids; 30167 Da
Subunit: Interacts with alpha-tubulin (By similarity)
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Nucleus. Cytoplasm. Note=Localizes to the manchette in
elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in
the nucleus in some primary epithelial cells and in a number of cell lines
Developmental stage: Expressed during in vitro differentiation of bronchial epithelial cells. In fetal lung, expression
is barely detectable at 10 weeks post-conception but is strong in airway epithelium at 12.3 weeks post-conception
Secondary accessions: Q5T598 Q5T599 Q5T5A0 Q8N9G4 Q96KD1 Q96LN1
Alternative splicing: 5 isoforms:  Q8NCR6-1   Q8NCR6-2   Q8NCR6-3   Q8NCR6-4   Q8NCR6-5   (No experimental confirmation available. Ref.2 (AAK53410) sequence is in conflict in position: 61:C->Y)

Explore the universe of human proteins at neXtProt for C9orf24: NX_Q8NCR6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8NCR6

    • C9orf24 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001239124.1  NP_115985.2  NP_671697.1  NP_671698.1  

    ENSEMBL proteins: 
     ENSP00000297623   ENSP00000368421   ENSP00000368428   ENSP00000368422   ENSP00000368407  
     ENSP00000368419   ENSP00000389687  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: C9orf24
    OriGene Protein Over-expression Lysate: C9orf24
    OriGene Custom Protein Services for C9orf24 
    GenScript Custom Purified and Recombinant Proteins Services for C9orf24
    Novus Biologicals C9orf24 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for C9orf24

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002177manchette ISS--
    GO:0005634nucleus IDA15242845
    GO:0005737cytoplasm ----
    GO:0048471perinuclear region of cytoplasm IDA15242845


    C9orf24 for ontologies           About GeneDecksing



    C9orf24 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for C9orf24 
    GenScript Custom Superior Antibodies Services for C9orf24
    Novus Biologicals C9orf24 Antibody
    Search for Antibodies for C9orf24 at Abcam  
    Uscn Antibodies for C9orf24
    ThermoFisher Antibody for C9orf24

    Assay Products for C9orf24: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for C9orf24
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for C9orf24

    Protein Domains /
    Families
    for C9orf24 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q8NCR6

    UniProtKB/Swiss-Prot: SMRP1_HUMAN, Q8NCR6
    Similarity: Belongs to the SMRP1 family


    Function
    for C9orf24 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: SMRP1_HUMAN, Q8NCR6
    Function: May play a role in spermatogenesis (By similarity). May be involved in differentiation or function of
    ciliated cells
    Induction: Down-regulated by IL13

    miRNA
    Products:            		 OriGene 3'-UTR Clone: C9orf24
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C9orf24
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate C9orf24
    SwitchGear 3'UTR luciferase reporter plasmid: C9orf24 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C9orf24 (see all 4)
    OriGene shRNA RFP: C9orf24
    OriGene siRNA: C9orf24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C9orf24

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for C9orf24

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24 (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): C9orf24 (NM_147168)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C9orf24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf24 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for C9orf24
    Search LifeMap BioReagents cell lines for C9orf24

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf24

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043014alpha-tubulin binding IEA--


    C9orf24 for ontologies           About GeneDecksing



    Pathways & Interactions
    for C9orf24 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C9orf24

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    2 Interacting proteins for C9orf24 (Q8NCR63 ENSP000002976234) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SHBGP042783, ENSP000003698164I2D: score=2 STRING: ENSP00000369816
    TSC22D4Q9Y3Q83I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007283spermatogenesis IEA--
    GO:0030154cell differentiation IEA--
    GO:0043623cellular protein complex assembly IEA--


    C9orf24 for ontologies           About GeneDecksing



    Drugs & Compounds
    for C9orf24 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for C9orf24
    Search CenterWatch for drugs/clinical trials and news about C9orf24 / SMRP1 

    Transcripts
    for C9orf24 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for C9orf24 gene (4 alternative transcripts): 
    NM_001252195.1  NM_032596.3  NM_147168.1  NM_147169.2  

    Unigene Cluster for C9orf24:

    Chromosome 9 open reading frame 24
    Hs.50334  [show with all ESTs]
    Unigene Representative Sequence: BM805429
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297623(uc003zuh.1) ENST00000379126 ENST00000379133(uc003zug.1 uc022bgb.1 uc003zuf.1 uc003zui.1)
    ENST00000379127 ENST00000379112 ENST00000379124 ENST00000481295 ENST00000444429


    miRNA
    Products:             		 OriGene 3'-UTR Clone: C9orf24
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat C9orf24
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate C9orf24
    SwitchGear 3'UTR luciferase reporter plasmid: C9orf24 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C9orf24 (see all 4)
    OriGene shRNA RFP: C9orf24
    OriGene siRNA: C9orf24
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C9orf24
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24 (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24 (see all 3)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): C9orf24 (NM_147168)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for C9orf24
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf24 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C9orf24
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C9orf24
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C9orf24
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C9orf24

    Additional cDNA sequence: 

    AF367474.1 AK058087.1 AK225981.1 BC022084.1 BC029484.1 

    3 DOTS entries:

    DT.211772  DT.97838571  DT.121171376 

    24/45 AceView cDNA sequences (see all 45):

    NM_147168 BC022084 AA450085 NM_032596 NM_147169 AA338648 AI332557 AW269443 
    BQ102504 BQ709331 CB155848 CK822850 AK094751 AI220552 AA868423 BC029484 
    AA729424 BM977422 BQ711948 BQ102465 T32089 AK058087 AF367474 AW961020 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for C9orf24    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b
    SP1:                    -     -     -                       -                     
    SP2:                                                        -                     
    SP3:                                                        -                     
    SP4:                                                  -     -                     
    SP5:                                                                              


    ECgene alternative splicing isoforms for C9orf24

    Expression
    for C9orf24 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    C9orf24 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTACGAAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    C9orf24 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    8 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BoneAutopod Long BoneBone
    BoneCaudal Endochondral BonesBone
    BoneEndochondral Facial BonesBone
    BoneStylopod Long BoneBone
    BoneThoracic RibBone
    BoneZeugopod Long BoneBone
    CartilageMeckel's CartilageCartilage
    LimbAutopodLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Dorsal forebrain-like neurons (Generation of midbra...)Brain

    See C9orf24 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for C9orf24

    SOURCE GeneReport for Unigene cluster: Hs.50334

    UniProtKB/Swiss-Prot: SMRP1_HUMAN, Q8NCR6
    Tissue specificity: Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from
    subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial
    cells along the basement membrane. Strongly expressed in ciliated epithelial cells with lower levels in goblet cells
    (at protein level)

        SABiosciences Custom PCR Arrays for C9orf24
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C9orf24
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C9orf24
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C9orf24
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C9orf24
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf24

    Orthologs
    for C9orf24 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for C9orf24 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia 1110017D15Rik1 , 5 RIKEN cDNA 1110017D15 gene1, 5 83.33(n)1
    76.92(a)1    		   4 (21.70 cM)5
    737211  NM_001048005.11  NP_001041470.11 
     415050095 
    chicken
    (Gallus gallus)    		 Aves CZH9orf241 chromosome Z open reading frame, human C9orf24 59.31(n)
    48.75(a)    		   427402  XM_424976.3  XP_424976.2 
    lizard
    (Anolis carolinensis)    		 Reptilia C9orf246
    		 --
    		 44(a)
    		 1 ↔ 1
    		 GL343482.1(474782-503885)


    ENSEMBL Gene Tree for C9orf24 (if available)
    TreeFam Gene Tree for C9orf24 (if available) 

    Paralogs
    for C9orf24 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for C9orf24 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/264 NCBI SNPs in C9orf24 are shown (see all 264)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1864594421,2
    		--34378900(+) GAAGGG/TCCCAG 4 -- ds50010--------
    rs1925842521,2
    		--34378944(+) TTGAAG/TGGGTT 4 -- ds50010--------
    rs38188301,2
    		C,F,A,H,--34378999(-) TGTCCA/TTACCC 4 -- ds500114Minor allele frequency- N:0.00EA NA NS WA 2340
    rs1855561811,2
    		C,--34379050(+) CTGCCC/TCCTTG 4 -- ut310--------
    rs1494638481,2
    		C--34379084(+) AGCAAC/TGATAG 6 H R mis1 ut311Minor allele frequency- T:0.00NA 4550
    rs1170284341,2
    		C,F,--34379108(+) CAGACA/GCAAAC 6 A V mis1 ut311Minor allele frequency- G:0.00NA 4550
    rs1472334001,2
    		C,--34379129(+) TAACAC/TAGTTG 6 Y C mis1 ut310--------
    rs1486402221,2
    		F--34379172(+) ACTTGT/CGTCCC 6 /T /A ut31 mis11Minor allele frequency- C:0.00NA 4550
    rs1421604351,2
    		F--34379176(+) GTGTCC/ACATCT 6 /W /C mis1 ut311Minor allele frequency- A:0.00NA 4550
    rs1121614031,2
    		C,--34379225(+) GTCAAC/AGTGAA 4 -- int11Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for C9orf24 (34379017 - 34397849 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for C9orf24: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C9orf24
    DNA2.0 Custom Variant and Variant Library Synthesis for C9orf24

    Disorders / Diseases
    for C9orf24 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    C9orf24 for disorders           About GeneDecksing

    2 diseases for C9orf24:    About MalaCards
    prostatitis    asthma


    Export disorders for C9orf24 gene to outside databases

    Publications
    for C9orf24 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for C9orf24 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with C9orf24)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development. (PubMed id 19213785)1, 2, 9 Haitchi H.M....Davies D.E. (2009)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Characterization of ciliated bronchial epithelium 1, a ciliated cell-associated gene induced during mucociliary differentiation. (PubMed id 15242845)1, 2 Yoshisue H....Holloway J.W. (2004)
    4. Identification of testis development and spermatogenesis-related genes in human and mouse testes using cDNA arrays. (PubMed id 12029067)1, 3 Sha J....Zhou K. (2002)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    6. Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin. (PubMed id 15862967)1 Pope S.N. and Lee I.R. (2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    8. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    External Searches for C9orf24 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing C9orf24 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84688 HGNC: 19919 AceView: C9orf24 Ensembl:ENSG00000164972 euGenes: HUgn84688
    ECgene: C9orf24 H-InvDB: C9orf24

    Other Databases showing C9orf24 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing C9orf24 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for C9orf24 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for C9orf24 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for C9orf24 gene:
    Search GeneIP for patents involving C9orf24

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for C9orf24 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for C9orf24  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C9orf24   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C9orf24  
     OriGene Protein Over-expression Lysate for C9orf24   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for C9orf24   OriGene 3'-UTR Clone for C9orf24  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C9orf24  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for C9orf24   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for C9orf24   OriGene Custom Protein Services for C9orf24  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat C9orf24
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C9orf24
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C9orf24
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat C9orf24
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C9orf24
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C9orf24
     GenScript Custom Purified and Recombinant Proteins Services for C9orf24 GenScript cDNA clones with any tag delivered in your preferred vector for C9orf24
     GenScript Custom Assay Services for C9orf24 GenScript Custom Superior Antibodies Services for C9orf24
     GenScript Custom overexpressing Cell Line Services for C9orf24 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in C9orf24 promoter
     Search Chromatin IP Primers for C9orf24
     RT2 qPCR Primer Assay in human, mouse, rat C9orf24
     Search GNC Networks for C9orf24
     SABiosciences Custom PCR Arrays for C9orf24
     Search Tocris compounds for C9orf24
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     C9orf24 antibodies
     C9orf24 lysates
     Search for Antibodies for C9orf24 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for C9orf24
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     C9orf24 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for C9orf24
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C9orf24
     SwitchGear 3'UTR luciferase reporter plasmids for C9orf24
     Browse SwitchGear Promoter luciferase reporter plasmids for C9orf24
     ThermoFisher Antibody for C9orf24
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C9orf24
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      C9orf24 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4