Free for academic non-profit institutions. Other users need a Commercial license

Aliases for C9orf173 Gene

Aliases for C9orf173 Gene

  • Chromosome 9 Open Reading Frame 173 2 3

External Ids for C9orf173 Gene

Previous GeneCards Identifiers for C9orf173 Gene

  • GC09P139267
  • GC09P140145
  • GC09P109605

Summaries for C9orf173 Gene

GeneCards Summary for C9orf173 Gene

C9orf173 (Chromosome 9 Open Reading Frame 173) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf173 Gene

Genomics for C9orf173 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C9orf173 Gene

137,250,840 bp from pter
137,253,483 bp from pter
2,644 bases
Plus strand

Genomic View for C9orf173 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C9orf173 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf173 Gene

No data available for Regulatory Elements for C9orf173 Gene

Proteins for C9orf173 Gene

  • Protein details for C9orf173 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C9orf173
    Protein Accession:
    Secondary Accessions:
    • A2RU24
    • B7ZM72
    • B7ZM76
    • Q8NEA3

    Protein attributes for C9orf173 Gene

    389 amino acids
    Molecular mass:
    42877 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C9orf173 Gene


neXtProt entry for C9orf173 Gene

Proteomics data for C9orf173 Gene at MOPED

Post-translational modifications for C9orf173 Gene

No Post-translational modifications

No data available for DME Specific Peptides for C9orf173 Gene

Domains & Families for C9orf173 Gene

Protein Domains for C9orf173 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf173: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf173 Gene

Function for C9orf173 Gene

genes like me logo Genes that share phenotypes with C9orf173: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf173

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C9orf173 Gene

Localization for C9orf173 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C9orf173 Gene

Pathways & Interactions for C9orf173 Gene

SuperPathways for C9orf173 Gene

No Data Available

Interacting Proteins for C9orf173 Gene

Gene Ontology (GO) - Biological Process for C9orf173 Gene


No data available for Pathways by source and SIGNOR curated interactions for C9orf173 Gene

Drugs & Compounds for C9orf173 Gene

No Compound Related Data Available

Transcripts for C9orf173 Gene

mRNA/cDNA for C9orf173 Gene

(6) REFSEQ mRNAs :
(10) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf173 Gene

Chromosome 9 open reading frame 173:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf173

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf173 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP1: - -
SP2: -
SP3: - - -

Relevant External Links for C9orf173 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf173 Gene

mRNA expression in normal human tissues for C9orf173 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf173 Gene

This gene is overexpressed in Testis (x30.1).

SOURCE GeneReport for Unigene cluster for C9orf173 Gene Hs.372640

genes like me logo Genes that share expression patterns with C9orf173: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for C9orf173 Gene

Orthologs for C9orf173 Gene

This gene was present in the common ancestor of chordates.

Orthologs for C9orf173 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia 4933433C11Rik 35
  • 74.75 (n)
  • 67.11 (a)
4933433C11Rik 16
4933433C11Rik 36
  • 55 (a)
(Pan troglodytes)
Mammalia C9H9orf173 35
  • 99.03 (n)
  • 98.38 (a)
C9orf173 36
  • 98 (a)
(Rattus norvegicus)
Mammalia LOC499746 35
  • 73.93 (n)
  • 67 (a)
(Canis familiaris)
Mammalia C9orf173 36
  • 59 (a)
(Monodelphis domestica)
Mammalia C9orf173 36
  • 40 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 18 (a)
Species with no ortholog for C9orf173:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf173 Gene

Gene Tree for C9orf173 (if available)
Gene Tree for C9orf173 (if available)

Paralogs for C9orf173 Gene

(1) SIMAP similar genes for C9orf173 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with C9orf173: view

No data available for Paralogs for C9orf173 Gene

Variants for C9orf173 Gene

Sequence variations from dbSNP and Humsavar for C9orf173 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
VAR_039898 -

Structural Variations from Database of Genomic Variants (DGV) for C9orf173 Gene

Variant ID Type Subtype PubMed ID
nsv894387 CNV Gain 21882294
esv2422220 CNV Deletion 17116639
dgv8412n71 CNV Loss 21882294
dgv8416n71 CNV Loss 21882294
nsv524322 CNV Loss 19592680
dgv8423n71 CNV Loss 21882294
nsv894502 CNV Loss 21882294
nsv894521 CNV Loss 21882294
dgv8442n71 CNV Loss 21882294
dgv8445n71 CNV Loss 21882294
dgv8446n71 CNV Loss 21882294
dgv8450n71 CNV Loss 21882294
nsv894603 CNV Gain+Loss 21882294
dgv8452n71 CNV Gain+Loss 21882294
dgv8453n71 CNV Gain 21882294
dgv8454n71 CNV Gain 21882294
dgv8455n71 CNV Gain+Loss 21882294
nsv894631 CNV Loss 21882294
dgv8457n71 CNV Gain 21882294
nsv894637 CNV Loss 21882294
nsv894642 CNV Loss 21882294

Variation tolerance for C9orf173 Gene

Residual Variation Intolerance Score: 84.27% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.34; 63.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C9orf173 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf173 Gene

Disorders for C9orf173 Gene

Relevant External Links for C9orf173

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C9orf173: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf173 Gene

Publications for C9orf173 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for C9orf173 Gene

Sources for C9orf173 Gene

Back to Top