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Aliases for C9orf170 Gene

Aliases for C9orf170 Gene

  • Chromosome 9 Open Reading Frame 170 2 3 5

External Ids for C9orf170 Gene

Previous GeneCards Identifiers for C9orf170 Gene

  • GC09P088954
  • GC09P089763
  • GC09P059590

Summaries for C9orf170 Gene

GeneCards Summary for C9orf170 Gene

C9orf170 (Chromosome 9 Open Reading Frame 170) is a Protein Coding gene.

Additional gene information for C9orf170 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf170 Gene

Genomics for C9orf170 Gene

Regulatory Elements for C9orf170 Gene

Enhancers for C9orf170 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H087266 1.6 FANTOM5 Ensembl ENCODE dbSUPER 14.2 +120.6 120610 5.6 ZSCAN4 FEZF1 ZNF2 ZNF302 FOS EGR2 OVOL3 TSHZ1 ZEB2 ZNF398 LOC494127 ELF2P3 ENSG00000232211 FBP2P1 ENSG00000229288 LOC102724080 C9orf170 GAS1RR GAS1 ENSG00000212421
GH09H087370 1.4 Ensembl ENCODE dbSUPER 10 +225.0 224965 6.9 FOXA2 SIN3A FEZF1 BATF RAD21 RARA YY1 GTF3C2 ZNF302 RCOR1 DAPK1 C9orf170 GC09P087380 GC09P087368 GC09P087367 GC09P087366 GC09P087365
GH09H087146 1 ENCODE dbSUPER 9 +0.0 46 3.4 ATF1 ZBTB40 BRCA1 RAD21 YY1 POLR2A SCRT2 NFE2 ATF7 CREM C9orf170 GAS1RR GC09P087261
GH09H087122 0.7 Ensembl ENCODE 12 -25.2 -25228 1.7 JUND POLR2A C9orf170 ENSG00000212421 GAS1RR GC09P087131 LOC494127
GH09H086720 1.3 Ensembl ENCODE dbSUPER 5.4 -426.4 -426403 3.1 GTF2F1 TBP PKNOX1 JUN MAX RAD21 BRCA1 RFX5 YY1 POLR2A C9orf170 DAPK1 GC09M086730 LOC105376124
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C9orf170 on UCSC Golden Path with GeneCards custom track

Promoters for C9orf170 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000237194 -44 401 CTCF ATF1 ZBTB40 BRCA1 RAD21 YY1 NFE2 ATF7 CREM CHD2

Genomic Locations for C9orf170 Gene

Genomic Locations for C9orf170 Gene
11,083 bases
Plus strand

Genomic View for C9orf170 Gene

Genes around C9orf170 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf170 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf170 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf170 Gene

Proteins for C9orf170 Gene

  • Protein details for C9orf170 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C9orf170
    Protein Accession:

    Protein attributes for C9orf170 Gene

    121 amino acids
    Molecular mass:
    13369 Da
    Quaternary structure:
    No Data Available

neXtProt entry for C9orf170 Gene

Post-translational modifications for C9orf170 Gene

No Post-translational modifications

Other Protein References for C9orf170 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C9orf170 Gene

Domains & Families for C9orf170 Gene

Protein Domains for C9orf170 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf170: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf170 Gene

Function for C9orf170 Gene

Phenotypes for C9orf170 Gene

GenomeRNAi human phenotypes for C9orf170:
genes like me logo Genes that share phenotypes with C9orf170: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C9orf170 Gene

Localization for C9orf170 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C9orf170 gene
Compartment Confidence
mitochondrion 3
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for C9orf170 Gene

Pathways & Interactions for C9orf170 Gene

SuperPathways for C9orf170 Gene

No Data Available

Interacting Proteins for C9orf170 Gene

Gene Ontology (GO) - Biological Process for C9orf170 Gene


No data available for Pathways by source and SIGNOR curated interactions for C9orf170 Gene

Drugs & Compounds for C9orf170 Gene

No Compound Related Data Available

Transcripts for C9orf170 Gene

mRNA/cDNA for C9orf170 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf170 Gene

Chromosome 9 open reading frame 170:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf170 Gene

No ASD Table

Relevant External Links for C9orf170 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf170 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C9orf170 Gene

NURSA nuclear receptor signaling pathways regulating expression of C9orf170 Gene:


SOURCE GeneReport for Unigene cluster for C9orf170 Gene:

genes like me logo Genes that share expression patterns with C9orf170: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C9orf170 Gene

Orthologs for C9orf170 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for C9orf170 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C9H9orf170 33
  • 97.8 (n)
C9orf170 34
  • 93 (a)
Species where no ortholog for C9orf170 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf170 Gene

Gene Tree for C9orf170 (if available)
Gene Tree for C9orf170 (if available)

Paralogs for C9orf170 Gene

No data available for Paralogs for C9orf170 Gene

Variants for C9orf170 Gene

Sequence variations from dbSNP and Humsavar for C9orf170 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000969197 -- 87,157,956(+) AACGA(A/C)CTACT utr-variant-3-prime
rs1001281339 -- 87,155,275(+) CTGCT(G/T)GGCTT intron-variant
rs1001486842 -- 87,148,655(+) GCCAG(A/C)GAGAG utr-variant-5-prime
rs1001492486 -- 87,157,248(+) ATATG(A/T)GGACT utr-variant-3-prime
rs1002228033 -- 87,149,600(+) CTGTT(A/G)TCAAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf170 Gene

Variant ID Type Subtype PubMed ID
nsv614785 CNV loss 21841781
nsv466430 CNV loss 19166990

Variation tolerance for C9orf170 Gene

Residual Variation Intolerance Score: 71.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.39; 8.67% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C9orf170 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf170 Gene

Disorders for C9orf170 Gene

Relevant External Links for C9orf170

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C9orf170 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf170 Gene

Publications for C9orf170 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PMID: 20889312) Wang KS … Aragam N (Schizophrenia research 2010) 45 60
  4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel DP … Karasik D (BMC medical genetics 2007) 45 60
  5. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr RH … Cho JH (Science (New York, N.Y.) 2006) 45 60

Products for C9orf170 Gene

Sources for C9orf170 Gene

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