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Aliases for C9orf153 Gene

Aliases for C9orf153 Gene

  • Chromosome 9 Open Reading Frame 153 2 3 5
  • Uncharacterized Protein C9orf153 3
  • BA507D14.1 3

External Ids for C9orf153 Gene

Previous GeneCards Identifiers for C9orf153 Gene

  • GC09M084293
  • GC09M086065
  • GC09M088026
  • GC09M088835
  • GC09M058664

Summaries for C9orf153 Gene

GeneCards Summary for C9orf153 Gene

C9orf153 (Chromosome 9 Open Reading Frame 153) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf153 Gene

Genomics for C9orf153 Gene

Regulatory Elements for C9orf153 Gene

Enhancers for C9orf153 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G086280 1.1 ENCODE 28.8 -22.7 -22703 2.8 HDGF PKNOX1 CREB3L1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 C9orf153 GAS1RR RN7SKP264 GAS1 ZCCHC6 ISCA1
GH09G086287 1.1 Ensembl ENCODE 19.7 -27.6 -27565 0.4 ATF1 ARID4B ZNF2 THRB RAD21 ZNF143 CREM THAP11 ZNF654 CEBPB C9orf153 ISCA1 GC09M086340
GH09G086256 0.3 FANTOM5 71.5 +3.6 3568 0.1 C9orf153 GOLM1 RN7SKP264 ENSG00000270688
GH09G086349 1.1 ENCODE 15.1 -93.4 -93425 6.2 HDGF PKNOX1 CREB3L1 ARNT WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 C9orf153 RN7SKP264 LOC389765 ZCCHC6 GC09M086340
GH09G086348 1.2 Ensembl ENCODE 13.6 -89.0 -89019 1.1 FOXA2 SIN3A ZNF121 GLIS2 FOS ZNF202 ZHX2 JUNB TSHZ1 ZNF518A C9orf153 GC09M086340 ZCCHC6
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around C9orf153 on UCSC Golden Path with GeneCards custom track

Genomic Location for C9orf153 Gene

Chromosome:
9
Start:
86,220,265 bp from pter
End:
86,259,657 bp from pter
Size:
39,393 bases
Orientation:
Minus strand

Genomic View for C9orf153 Gene

Genes around C9orf153 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf153 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf153 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf153 Gene

Proteins for C9orf153 Gene

  • Protein details for C9orf153 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TBE3-CI153_HUMAN
    Recommended name:
    Uncharacterized protein C9orf153
    Protein Accession:
    Q5TBE3
    Secondary Accessions:
    • Q5TBE4

    Protein attributes for C9orf153 Gene

    Size:
    101 amino acids
    Molecular mass:
    11254 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C9orf153 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C9orf153 Gene

Post-translational modifications for C9orf153 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C9orf153 Gene

No data available for DME Specific Peptides for C9orf153 Gene

Domains & Families for C9orf153 Gene

Protein Domains for C9orf153 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf153: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf153 Gene

Function for C9orf153 Gene

Phenotypes for C9orf153 Gene

GenomeRNAi human phenotypes for C9orf153:
genes like me logo Genes that share phenotypes with C9orf153: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C9orf153 Gene

Localization for C9orf153 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for C9orf153 gene
Compartment Confidence
nucleus 2
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C9orf153 Gene

Pathways & Interactions for C9orf153 Gene

SuperPathways for C9orf153 Gene

No Data Available

Interacting Proteins for C9orf153 Gene

Gene Ontology (GO) - Biological Process for C9orf153 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C9orf153 Gene

Drugs & Compounds for C9orf153 Gene

No Compound Related Data Available

Transcripts for C9orf153 Gene

Unigene Clusters for C9orf153 Gene

Chromosome 9 open reading frame 153:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf153 Gene

No ASD Table

Relevant External Links for C9orf153 Gene

GeneLoc Exon Structure for
C9orf153
ECgene alternative splicing isoforms for
C9orf153

Expression for C9orf153 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for C9orf153 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf153 Gene

This gene is overexpressed in Testis (x41.9).

NURSA nuclear receptor signaling pathways regulating expression of C9orf153 Gene:

C9orf153

SOURCE GeneReport for Unigene cluster for C9orf153 Gene:

Hs.632073
genes like me logo Genes that share expression patterns with C9orf153: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for C9orf153 Gene

Orthologs for C9orf153 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C9orf153 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf153 34
  • 98.95 (n)
C9orf153 35
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9orf153 35
  • 16 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C9orf153 35
  • 13 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 4921517D22Rik 35
  • 13 (a)
OneToOne
Species where no ortholog for C9orf153 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf153 Gene

ENSEMBL:
Gene Tree for C9orf153 (if available)
TreeFam:
Gene Tree for C9orf153 (if available)

Paralogs for C9orf153 Gene

No data available for Paralogs for C9orf153 Gene

Variants for C9orf153 Gene

Sequence variations from dbSNP and Humsavar for C9orf153 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000033238 -- 86,248,663(+) TTACA(A/C)CCCCT intron-variant
rs1000135746 -- 86,259,654(+) CCCAG(A/C)CCCAC utr-variant-5-prime
rs1000296061 -- 86,235,052(+) GGAAG(C/T)TCCTC intron-variant
rs1000375751 -- 86,253,351(+) TAAGT(A/G)AAGAA intron-variant
rs1000439547 -- 86,228,925(+) GAGCT(C/G)TGCTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf153 Gene

Variant ID Type Subtype PubMed ID
esv3620954 CNV loss 21293372
esv3620955 CNV loss 21293372
esv3891691 CNV loss 25118596
nsv1041191 CNV gain 25217958
nsv1161880 CNV deletion 26073780

Variation tolerance for C9orf153 Gene

Residual Variation Intolerance Score: 59.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.17; 39.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C9orf153 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
C9orf153

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf153 Gene

Disorders for C9orf153 Gene

Relevant External Links for C9orf153

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C9orf153

No disorders were found for C9orf153 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf153 Gene

Publications for C9orf153 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C9orf153 Gene

Sources for C9orf153 Gene

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