Aliases for C9orf142 Gene
External Ids for C9orf142 Gene
Previous GeneCards Identifiers for C9orf142 Gene
The protein encoded by this gene plays a role in the nonhomologous end joining (NHEJ) pathway of DNA double-strand break repair. The encoded protein may function to stabilize the Ku70/Ku80 heterodimer to facilitate the assembly and maintain the stability of the NHEJ complex. [provided by RefSeq, Jul 2016]
GeneCards Summary for C9orf142 Gene
C9orf142 (Chromosome 9 Open Reading Frame 142) is a Protein Coding gene. GO annotations related to this gene include protein homodimerization activity.
UniProtKB/Swiss-Prot for C9orf142 Gene
Involved in non-homologous end joining (NHEJ), a major pathway to repair double-strand breaks in DNA. May act as a scaffold required to stabilize the Ku heterodimer, composed of XRCC5/Ku80 and XRCC6/Ku70, at double-strand break sites and promote the assembly and/or stability of the NHEJ machinery.