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Aliases for C9orf139 Gene

Aliases for C9orf139 Gene

  • Chromosome 9 Open Reading Frame 139 2 3 5

External Ids for C9orf139 Gene

Previous GeneCards Identifiers for C9orf139 Gene

  • GC09P139041
  • GC09P139921
  • GC09P109381

Summaries for C9orf139 Gene

GeneCards Summary for C9orf139 Gene

C9orf139 (Chromosome 9 Open Reading Frame 139) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf139 Gene

Genomics for C9orf139 Gene

Regulatory Elements for C9orf139 Gene

Enhancers for C9orf139 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F136990 1.3 FANTOM5 Ensembl ENCODE 11.9 -31.1 -31070 11.6 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 CBX5 ENSG00000238268 LCN12 ABCA2 ANAPC2 PRR31 C9orf139 SNHG7 LCNL1 RABL6 CCDC183
GH09F136884 0.7 ENCODE 11.4 -141.2 -141190 3.1 HDGF PKNOX1 CREB3L1 ARID4B SIN3A DMAP1 ZNF207 ZNF143 FOS CEBPZ PHPT1 SNHG7 MAMDC4 C9orf172 C8G FBXW5 LCN12 TMEM141 PRR31 CCDC183-AS1
GH09F136881 0.2 ENCODE 11.4 -144.8 -144802 2.7 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 GLIS2 ELK1 PHPT1 MAMDC4 C9orf172 TMEM141 LCN12 PRR31 C8G FBXW5 RABL6 C9orf139
GH09F137156 0.5 ENCODE 11 +129.5 129534 1.2 KLF1 CBX3 ZNF2 ZNF324 ZFHX2 GLIS2 POLR2A PATZ1 PRDM10 KLF7 MAN1B1 ANAPC2 SSNA1 TPRN DPP7 NDOR1 TMEM203 ABCA2 C9orf139 UAP1L1
GH09F137023 1 Ensembl ENCODE 0.8 -4.1 -4064 0.4 TFAP4 NFIA NR2F1 BCL11B ZBTB7A ZIC2 NR2F2 BCL11A POLR2A NR2F6 LCNL1 C9orf139 PIR32105
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around C9orf139 on UCSC Golden Path with GeneCards custom track

Promoters for C9orf139 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001914620 836 1401 ZNF2 GLIS2 ZNF143 KLF7 SP3 SMARCB1 SMARCA4 GLIS1 MXD3 WT1

Genomic Location for C9orf139 Gene

137,027,464 bp from pter
137,037,957 bp from pter
10,494 bases
Plus strand

Genomic View for C9orf139 Gene

Genes around C9orf139 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf139 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf139 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf139 Gene

Proteins for C9orf139 Gene

  • Protein details for C9orf139 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C9orf139
    Protein Accession:
    Secondary Accessions:
    • A2RUA3
    • B9EGW2
    • Q5SPY0
    • Q8N224

    Protein attributes for C9orf139 Gene

    190 amino acids
    Molecular mass:
    20001 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC04202.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for C9orf139 Gene

Post-translational modifications for C9orf139 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C9orf139 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for C9orf139 Gene

Domains & Families for C9orf139 Gene

Protein Domains for C9orf139 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf139: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf139 Gene

Function for C9orf139 Gene

genes like me logo Genes that share phenotypes with C9orf139: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for C9orf139 Gene

Localization for C9orf139 Gene

Subcellular locations from

Jensen Localization Image for C9orf139 Gene COMPARTMENTS Subcellular localization image for C9orf139 gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C9orf139 Gene

Pathways & Interactions for C9orf139 Gene

SuperPathways for C9orf139 Gene

No Data Available

Interacting Proteins for C9orf139 Gene

Gene Ontology (GO) - Biological Process for C9orf139 Gene


No data available for Pathways by source and SIGNOR curated interactions for C9orf139 Gene

Transcripts for C9orf139 Gene

mRNA/cDNA for C9orf139 Gene

(2) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C9orf139 Gene

Chromosome 9 open reading frame 139:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf139 Gene

No ASD Table

Relevant External Links for C9orf139 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C9orf139 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for C9orf139 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf139 Gene

This gene is overexpressed in Whole Blood (x23.3) and Spleen (x4.3).

NURSA nuclear receptor signaling pathways regulating expression of C9orf139 Gene:


SOURCE GeneReport for Unigene cluster for C9orf139 Gene:

genes like me logo Genes that share expression patterns with C9orf139: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for C9orf139 Gene

Orthologs for C9orf139 Gene

Evolution for C9orf139 Gene

Gene Tree for C9orf139 (if available)
Gene Tree for C9orf139 (if available)

No data available for Orthologs for C9orf139 Gene

Paralogs for C9orf139 Gene

No data available for Paralogs for C9orf139 Gene

Variants for C9orf139 Gene

Sequence variations from dbSNP and Humsavar for C9orf139 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000324 -- 137,033,913(-) CGCGT(C/T)CTCAT intron-variant, upstream-variant-2KB
rs10732706 -- 137,032,508(+) TCCCA(C/T)GGCAG intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs111361035 -- 137,033,213(+) GACGT(C/T)CTGGA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs11145973 -- 137,031,007(+) AGTGC(A/G)TTGCG intron-variant, upstream-variant-2KB, reference, synonymous-codon
rs111533695 -- 137,035,020(+) CAGGG(G/T)CTCCC nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C9orf139 Gene

Variant ID Type Subtype PubMed ID
dgv13007n54 CNV loss 21841781
esv2422220 CNV deletion 17116639
esv2761561 CNV gain 21179565
esv3332181 CNV duplication 20981092
nsv1077200 CNV deletion 25765185
nsv1113023 CNV deletion 24896259
nsv1119617 CNV deletion 24896259
nsv469918 CNV loss 18288195
nsv513004 CNV insertion 21212237
nsv524322 CNV loss 19592680
nsv616004 CNV loss 21841781
nsv616005 CNV loss 21841781
nsv951206 CNV deletion 24416366

Variation tolerance for C9orf139 Gene

Residual Variation Intolerance Score: 95.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.09; 50.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C9orf139 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf139 Gene

Disorders for C9orf139 Gene

Relevant External Links for C9orf139

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for C9orf139 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf139 Gene

Publications for C9orf139 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for C9orf139 Gene

Sources for C9orf139 Gene

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