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Aliases for C9orf131 Gene

Aliases for C9orf131 Gene

  • Chromosome 9 Open Reading Frame 131 2 3 5

External Ids for C9orf131 Gene

Previous GeneCards Identifiers for C9orf131 Gene

  • GC09P035034
  • GC09P034996

Summaries for C9orf131 Gene

GeneCards Summary for C9orf131 Gene

C9orf131 (Chromosome 9 Open Reading Frame 131) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf131 Gene

Genomics for C9orf131 Gene

Regulatory Elements for C9orf131 Gene

Enhancers for C9orf131 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around C9orf131 on UCSC Golden Path with GeneCards custom track

Genomic Location for C9orf131 Gene

Chromosome:
9
Start:
35,041,095 bp from pter
End:
35,045,991 bp from pter
Size:
4,897 bases
Orientation:
Plus strand

Genomic View for C9orf131 Gene

Genes around C9orf131 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
C9orf131 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for C9orf131 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf131 Gene

Proteins for C9orf131 Gene

  • Protein details for C9orf131 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VYM1-CI131_HUMAN
    Recommended name:
    Uncharacterized protein C9orf131
    Protein Accession:
    Q5VYM1
    Secondary Accessions:
    • A6NLE6
    • E9PB26
    • Q86XC6
    • Q9UF74

    Protein attributes for C9orf131 Gene

    Size:
    1079 amino acids
    Molecular mass:
    117724 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH45643.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C9orf131 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C9orf131 Gene

Proteomics data for C9orf131 Gene at MOPED

Post-translational modifications for C9orf131 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for C9orf131 Gene

Domains & Families for C9orf131 Gene

Protein Domains for C9orf131 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf131: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf131 Gene

Function for C9orf131 Gene

genes like me logo Genes that share phenotypes with C9orf131: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for C9orf131 Gene

Localization for C9orf131 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C9orf131 Gene COMPARTMENTS Subcellular localization image for C9orf131 gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C9orf131 Gene

Pathways & Interactions for C9orf131 Gene

SuperPathways for C9orf131 Gene

No Data Available

Interacting Proteins for C9orf131 Gene

Gene Ontology (GO) - Biological Process for C9orf131 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for C9orf131 Gene

Drugs & Compounds for C9orf131 Gene

No Compound Related Data Available

Transcripts for C9orf131 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf131 Gene

No ASD Table

Relevant External Links for C9orf131 Gene

GeneLoc Exon Structure for
C9orf131
ECgene alternative splicing isoforms for
C9orf131

Expression for C9orf131 Gene

mRNA expression in normal human tissues for C9orf131 Gene

mRNA differential expression in normal tissues according to GTEx for C9orf131 Gene

This gene is overexpressed in Testis (x42.6).

Protein differential expression in normal tissues from HIPED for C9orf131 Gene

This gene is overexpressed in Ovary (37.1) and Spleen (18.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C9orf131 Gene



SOURCE GeneReport for Unigene cluster for C9orf131 Gene Hs.148250

genes like me logo Genes that share expression patterns with C9orf131: view

Protein tissue co-expression partners for C9orf131 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for C9orf131 Gene

Orthologs for C9orf131 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C9orf131 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C8H9orf131 35
  • 76.65 (n)
  • 58.7 (a)
dog
(Canis familiaris)
Mammalia C11H9orf131 35
  • 79.3 (n)
  • 64.95 (a)
C9orf131 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700022I11Rik 35
  • 69.22 (n)
  • 48.72 (a)
1700022I11Rik 16
1700022I11Rik 36
  • 44 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf131 35
  • 98.63 (n)
  • 97.32 (a)
C9orf131 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC100360821 35
  • 68.73 (n)
  • 48.52 (a)
Species with no ortholog for C9orf131:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C9orf131 Gene

ENSEMBL:
Gene Tree for C9orf131 (if available)
TreeFam:
Gene Tree for C9orf131 (if available)

Paralogs for C9orf131 Gene

No data available for Paralogs for C9orf131 Gene

Variants for C9orf131 Gene

Sequence variations from dbSNP and Humsavar for C9orf131 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs615474 - 35,043,294(+) GAAGT(G/T)GTCTG reference, missense
rs10117097 - 35,043,482(+) CACTA(C/T)TCCTC reference, missense
rs35523761 - 35,043,938(-) AGAGA(C/G)CTCTG reference, missense
rs2298312 - 35,044,496(-) CTGAG(A/T)ATCAG reference, missense
rs3739871 - 35,045,375(-) GCCTG(A/G)AGATA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for C9orf131 Gene

Variant ID Type Subtype PubMed ID
nsv893043 CNV Gain 21882294

Variation tolerance for C9orf131 Gene

Residual Variation Intolerance Score: 86.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.38; 71.00% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for C9orf131 Gene

Disorders for C9orf131 Gene

Relevant External Links for C9orf131

Genetic Association Database (GAD)
C9orf131
Human Genome Epidemiology (HuGE) Navigator
C9orf131
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
C9orf131

No disorders were found for C9orf131 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C9orf131 Gene

Publications for C9orf131 Gene

  1. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PMID: 21083371) Chinn L.W. … O'Brien S.J. (J. Infect. Dis. 2010) 48 67
  2. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C9orf131 Gene

Sources for C9orf131 Gene

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