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Aliases for C9orf117 Gene

Aliases for C9orf117 Gene

  • Chromosome 9 Open Reading Frame 117 2 3

External Ids for C9orf117 Gene

Previous GeneCards Identifiers for C9orf117 Gene

  • GC09P125846
  • GC09P127548
  • GC09P129509
  • GC09P130469
  • GC09P100085

Summaries for C9orf117 Gene

GeneCards Summary for C9orf117 Gene

C9orf117 (Chromosome 9 Open Reading Frame 117) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C9orf117 Gene

Genomics for C9orf117 Gene

Regulatory Elements for C9orf117 Gene

Genomic Location for C9orf117 Gene

Start:
127,706,984 bp from pter
End:
127,716,002 bp from pter
Size:
9,019 bases
Orientation:
Plus strand

Genomic View for C9orf117 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C9orf117 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C9orf117 Gene

Proteins for C9orf117 Gene

  • Protein details for C9orf117 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JU67-CI117_HUMAN
    Recommended name:
    Uncharacterized protein C9orf117
    Protein Accession:
    Q5JU67
    Secondary Accessions:
    • A5D8T9

    Protein attributes for C9orf117 Gene

    Size:
    520 amino acids
    Molecular mass:
    60533 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for C9orf117 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C9orf117 Gene

Proteomics data for C9orf117 Gene at MOPED

Post-translational modifications for C9orf117 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C9orf117 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for C9orf117 Gene

Domains for C9orf117 Gene

Protein Domains for C9orf117 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C9orf117: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for C9orf117 Gene

Function for C9orf117 Gene

Phenotypes for C9orf117 Gene

GenomeRNAi human phenotypes for C9orf117:
genes like me logo Genes that share phenotypes with C9orf117: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf117

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C9orf117 Gene

Localization for C9orf117 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C9orf117 Gene COMPARTMENTS Subcellular localization image for C9orf117 gene
Compartment Confidence
cytosol 3
nucleus 3
plasma membrane 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for C9orf117 Gene

Pathways for C9orf117 Gene

SuperPathways for C9orf117 Gene

No Data Available

Interacting Proteins for C9orf117 Gene

Gene Ontology (GO) - Biological Process for C9orf117 Gene

None

No data available for Pathways by source for C9orf117 Gene

Transcripts for C9orf117 Gene

mRNA/cDNA for C9orf117 Gene

Unigene Clusters for C9orf117 Gene

Chromosome 9 open reading frame 117:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C9orf117

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C9orf117 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d ^ 5 ^ 6
SP1:
SP2: -
SP3: - -
SP4:

Relevant External Links for C9orf117 Gene

GeneLoc Exon Structure for
C9orf117
ECgene alternative splicing isoforms for
C9orf117

Expression for C9orf117 Gene

mRNA expression in normal human tissues for C9orf117 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for C9orf117 Gene

This gene is overexpressed in Fallopian Tube (9.5), Cervix - Endocervix (7.7), Brain - Caudate (basal ganglia) (4.8), Brain - Hypothalamus (4.6), and Testis (4.3).

Protein differential expression in normal tissues for C9orf117 Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C9orf117 Gene

SOURCE GeneReport for Unigene cluster for C9orf117 Gene Hs.652519

genes like me logo Genes that share expressions with C9orf117: view

Expression partners for C9orf117 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for C9orf117 Gene

Orthologs for C9orf117 Gene

This gene was present in the common ancestor of animals.

Orthologs for C9orf117 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia C11H9orf117 35
  • 81.88 (n)
  • 71.18 (a)
C9orf117 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H9orf117 35
  • 81.88 (n)
  • 75.53 (a)
C9orf117 36
  • 71 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700019L03Rik 35
  • 77.17 (n)
  • 65.95 (a)
1700019L03Rik 16
1700019L03Rik 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C9H9orf117 35
  • 99.1 (n)
  • 98.46 (a)
C9orf117 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC499781 35
  • 76.41 (n)
  • 66.47 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia C9orf117 36
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia c9orf117 35
  • 55.8 (n)
  • 46.26 (a)
zebrafish
(Danio rerio)
Actinopterygii si:ch211-233f10.4 35
  • 51.41 (n)
  • 38.8 (a)
C5H9orf117 36
  • 36 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG17122 36
  • 17 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 36 (a)
OneToOne
Species with no ortholog for C9orf117:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for C9orf117 Gene

ENSEMBL:
Gene Tree for C9orf117 (if available)
TreeFam:
Gene Tree for C9orf117 (if available)

Paralogs for C9orf117 Gene

No data available for Paralogs for C9orf117 Gene

Variants for C9orf117 Gene

Sequence variations from dbSNP and Humsavar for C9orf117 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs497632 - 127,713,163(-) TGATA(G/T)ATGAC reference, missense, intron-variant
rs522328 -- 127,712,732(-) ACGTC(A/G)CTGTC synonymous-codon, reference
rs1756008 -- 127,706,294(+) GCCCC(C/T)GCCCC upstream-variant-2KB
rs7848745 -- 127,707,656(+) aagtg(A/G)ggaag intron-variant
rs7849115 -- 127,707,896(+) TGGGT(A/G)ACCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C9orf117 Gene

Variant ID Type Subtype PubMed ID
nsv893859 CNV Loss 21882294
nsv893860 CNV Gain 21882294
nsv893865 CNV Loss 21882294
nsv893866 CNV Gain 21882294
nsv893867 CNV Loss 21882294
nsv893868 CNV Loss 21882294
dgv8287n71 CNV Loss 21882294
nsv466571 CNV Loss 19166990

Relevant External Links for C9orf117 Gene

HapMap Linkage Disequilibrium report
C9orf117

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C9orf117 Gene

Disorders for C9orf117 Gene

No disorders were found for C9orf117 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for C9orf117 Gene

Publications for C9orf117 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PMID: 21145461) Bennett E.J. … Harper J.W. (Cell 2010) 3
  4. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for C9orf117 Gene

Sources for C9orf117 Gene

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