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Aliases for C8orf58 Gene

Aliases for C8orf58 Gene

  • Chromosome 8 Open Reading Frame 58 2 3

External Ids for C8orf58 Gene

Previous GeneCards Identifiers for C8orf58 Gene

  • GC08U900616
  • GC08P022513
  • GC08P022446
  • GC08P022457
  • GC08P020999

Summaries for C8orf58 Gene

GeneCards Summary for C8orf58 Gene

C8orf58 (Chromosome 8 Open Reading Frame 58) is a Protein Coding gene. An important paralog of this gene is ENSG00000248235.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf58 Gene

Genomics for C8orf58 Gene

Regulatory Elements for C8orf58 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for C8orf58 Gene

22,599,601 bp from pter
22,604,150 bp from pter
4,550 bases
Plus strand

Genomic View for C8orf58 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C8orf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf58 Gene

Proteins for C8orf58 Gene

  • Protein details for C8orf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein C8orf58
    Protein Accession:
    Secondary Accessions:
    • B4DI44

    Protein attributes for C8orf58 Gene

    365 amino acids
    Molecular mass:
    39661 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC03795.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C8orf58 Gene


neXtProt entry for C8orf58 Gene

Proteomics data for C8orf58 Gene at MOPED

Post-translational modifications for C8orf58 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for C8orf58 Gene

No data available for DME Specific Peptides for C8orf58 Gene

Domains & Families for C8orf58 Gene

Protein Domains for C8orf58 Gene


Suggested Antigen Peptide Sequences for C8orf58 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with C8orf58: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C8orf58 Gene

Function for C8orf58 Gene

Phenotypes for C8orf58 Gene

GenomeRNAi human phenotypes for C8orf58:
genes like me logo Genes that share phenotypes with C8orf58: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C8orf58

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for C8orf58 Gene

Localization for C8orf58 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for C8orf58 Gene

Pathways & Interactions for C8orf58 Gene

SuperPathways for C8orf58 Gene

No Data Available

Interacting Proteins for C8orf58 Gene

Gene Ontology (GO) - Biological Process for C8orf58 Gene


No data available for Pathways by source and SIGNOR curated interactions for C8orf58 Gene

Drugs & Compounds for C8orf58 Gene

No Compound Related Data Available

Transcripts for C8orf58 Gene

mRNA/cDNA for C8orf58 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C8orf58 Gene

Chromosome 8 open reading frame 58:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for C8orf58

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf58 Gene

No ASD Table

Relevant External Links for C8orf58 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for C8orf58 Gene

mRNA expression in normal human tissues for C8orf58 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for C8orf58 Gene

SOURCE GeneReport for Unigene cluster for C8orf58 Gene Hs.743508

genes like me logo Genes that share expression patterns with C8orf58: view

Protein tissue co-expression partners for C8orf58 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for C8orf58 Gene

Orthologs for C8orf58 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C8orf58 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C8H8orf58 35
  • 75.72 (n)
  • 61.5 (a)
-- 36
  • 57 (a)
(Canis familiaris)
Mammalia C25H8orf58 35
  • 78.66 (n)
  • 67.31 (a)
-- 36
  • 63 (a)
(Mus musculus)
Mammalia 9930012K11Rik 35
  • 74.12 (n)
  • 63.97 (a)
9930012K11Rik 16
9930012K11Rik 36
  • 61 (a)
(Rattus norvegicus)
Mammalia RGD1308117 35
  • 74.14 (n)
  • 64.43 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 40 (a)
Species with no ortholog for C8orf58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf58 Gene

Gene Tree for C8orf58 (if available)
Gene Tree for C8orf58 (if available)

Paralogs for C8orf58 Gene

Paralogs for C8orf58 Gene

genes like me logo Genes that share paralogs with C8orf58: view

Variants for C8orf58 Gene

Sequence variations from dbSNP and Humsavar for C8orf58 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs746011 -- 22,600,291(-) CTGAA(A/G)TGAAA intron-variant
rs755934 -- 22,599,692(+) CTGCA(G/T)TGGCC utr-variant-5-prime
rs755935 -- 22,599,693(+) TGCAT(C/T)GGCCG utr-variant-5-prime
rs900273 -- 22,601,560(+) GGCAC(C/T)ATGCC intron-variant
rs2272717 -- 22,599,793(+) GGCTC(A/C)CCCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C8orf58 Gene

Variant ID Type Subtype PubMed ID
essv19243 CNV CNV 17122850
essv21913 CNV CNV 17122850
nsv890673 CNV Loss 21882294
dgv7762n71 CNV Loss 21882294

Variation tolerance for C8orf58 Gene

Residual Variation Intolerance Score: 87.45% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.64; 45.50% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for C8orf58 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for C8orf58 Gene

Disorders for C8orf58 Gene

Relevant External Links for C8orf58

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with C8orf58: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for C8orf58 Gene

Publications for C8orf58 Gene

  1. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 67
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  3. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for C8orf58 Gene

Sources for C8orf58 Gene

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