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Aliases for C8orf58 Gene

Aliases for C8orf58 Gene

  • Chromosome 8 Open Reading Frame 58 2 3

External Ids for C8orf58 Gene

Summaries for C8orf58 Gene

GeneCards Summary for C8orf58 Gene

C8orf58 (Chromosome 8 Open Reading Frame 58) is a Protein Coding gene. An important paralog of this gene is ENSG00000248235.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for C8orf58 Gene

Genomics for C8orf58 Gene

Genomic Location for C8orf58 Gene

Start:
22,599,601 bp from pter
End:
22,604,150 bp from pter
Size:
4,550 bases
Orientation:
Plus strand

Genomic View for C8orf58 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for C8orf58 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for C8orf58 Gene

Regulatory Elements for C8orf58 Gene

Proteins for C8orf58 Gene

  • Protein details for C8orf58 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NAV2-CH058_HUMAN
    Recommended name:
    Uncharacterized protein C8orf58
    Protein Accession:
    Q8NAV2
    Secondary Accessions:
    • B4DI44

    Protein attributes for C8orf58 Gene

    Size:
    365 amino acids
    Molecular mass:
    39661 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC03795.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for C8orf58 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for C8orf58 Gene

Proteomics data for C8orf58 Gene at MOPED

Post-translational modifications for C8orf58 Gene

No Post-translational modifications

Other Protein References for C8orf58 Gene

No data available for DME Specific Peptides for C8orf58 Gene

Domains for C8orf58 Gene

Protein Domains for C8orf58 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with C8orf58: view

No data available for Gene Families and UniProtKB/Swiss-Prot for C8orf58 Gene

Function for C8orf58 Gene

Phenotypes for C8orf58 Gene

GenomeRNAi human phenotypes for C8orf58:
genes like me logo Genes that share phenotypes with C8orf58: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for C8orf58 Gene

Localization for C8orf58 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for C8orf58 Gene COMPARTMENTS Subcellular localization image for C8orf58 gene
Compartment Confidence
nucleus 4
cytoskeleton 3
mitochondrion 2
cytosol 1
extracellular 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for C8orf58 Gene

Pathways for C8orf58 Gene

SuperPathways for C8orf58 Gene

No Data Available

Interacting Proteins for C8orf58 Gene

Gene Ontology (GO) - Biological Process for C8orf58 Gene

None

No data available for Pathways by source for C8orf58 Gene

Transcripts for C8orf58 Gene

mRNA/cDNA for C8orf58 Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for C8orf58 Gene

Chromosome 8 open reading frame 58:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for C8orf58 Gene

No ASD Table

Relevant External Links for C8orf58 Gene

GeneLoc Exon Structure for
C8orf58
ECgene alternative splicing isoforms for
C8orf58

Expression for C8orf58 Gene

mRNA expression in normal human tissues for C8orf58 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for C8orf58 Gene

SOURCE GeneReport for Unigene cluster for C8orf58 Gene Hs.743508

genes like me logo Genes that share expressions with C8orf58: view

Orthologs for C8orf58 Gene

This gene was present in the common ancestor of mammals.

Orthologs for C8orf58 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 37
  • 57 (a)
OneToMany
C8H8orf58 36
  • 75.72 (n)
  • 61.5 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 63 (a)
OneToMany
C25H8orf58 36
  • 78.66 (n)
  • 67.31 (a)
mouse
(Mus musculus)
Mammalia 9930012K11Rik 36
  • 74.12 (n)
  • 63.97 (a)
9930012K11Rik 16
9930012K11Rik 37
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 40 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1308117 36
  • 74.14 (n)
  • 64.43 (a)
Species with no ortholog for C8orf58:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for C8orf58 Gene

ENSEMBL:
Gene Tree for C8orf58 (if available)
TreeFam:
Gene Tree for C8orf58 (if available)

Paralogs for C8orf58 Gene

Paralogs for C8orf58 Gene

genes like me logo Genes that share paralogs with C8orf58: view

Variants for C8orf58 Gene

Sequence variations from dbSNP and Humsavar for C8orf58 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs746011 -- 22,600,291(-) CTGAA(A/G)TGAAA intron-variant
rs755934 -- 22,599,692(+) CTGCA(G/T)TGGCC utr-variant-5-prime
rs755935 -- 22,599,693(+) TGCAT(C/T)GGCCG utr-variant-5-prime
rs900273 -- 22,601,560(+) GGCAC(C/T)ATGCC intron-variant
rs2272717 -- 22,599,793(+) GGCTC(A/C)CCCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for C8orf58 Gene

Variant ID Type Subtype PubMed ID
essv19243 CNV CNV 17122850
essv21913 CNV CNV 17122850
nsv890673 CNV Loss 21882294
dgv7762n71 CNV Loss 21882294

Relevant External Links for C8orf58 Gene

HapMap Linkage Disequilibrium report
C8orf58

Disorders for C8orf58 Gene

No disorders were found for C8orf58 Gene.

No data available for UniProtKB/Swiss-Prot for C8orf58 Gene

Publications for C8orf58 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for C8orf58 Gene

Sources for C8orf58 Gene

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