C8orf47 Gene
protein-coding GIFtS: 37
GCID: GC08P099076
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chromosome 8 open reading frame 47
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Aliases
for C8orf47 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Chromosome 8 Open Reading Frame 471 2 | | FLJ395531 | | Uncharacterized Protein C8orf472 |
Export aliases for C8orf47 gene to outside databasesPrevious GC identifers: GC08P099146 GC08P094280 |
Summaries
for C8orf47 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for C8orf47 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the C8orf47 gene promoter:
USF1 Sox5 Pbx1a AML1a FOXO3 FOXO3b USF-1 FOXO3a Chx10 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for C8orf47
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat C8orf47 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q22.2 Ensembl cytogenetic band: 8q22.2 HGNC cytogenetic band: 8q22.2C8orf47 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P099076: view genomic region
(about GC identifiers)
Start:
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99,076,539 bp from pter |
End:
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99,105,838 bp from pter |
Size:
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29,300 bases |
Orientation:
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plus strand |
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Proteins
for C8orf47 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CH047_HUMAN, Q6P6B1 (See
protein sequence)Recommended Name: Uncharacterized protein C8orf47 Size: 374 amino acids; 39936 Da
Secondary accessions: Q8N1L8Explore the universe of human proteins at neXtProt for C8orf47: NX_Q6P6B1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6P6B1
C8orf47 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001164277.1 NP_775820.2
ENSEMBL proteins: ENSP00000315614 ENSP00000440297
Human Recombinant Protein Products for C8orf47:
C8orf47 Antibody Products:
Assay Products for C8orf47: |
Protein
Domains /
Families
for C8orf47 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6P6B1 |
Function
for C8orf47 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): C8orf47 (NM_173549) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C8orf47 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C8orf47 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C8orf47 |
|
Pathways & Interactions
for C8orf47 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for C8orf47
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for C8orf47 (ENSP000003156144) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for C8orf47 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for C8orf47
Search CenterWatch for drugs/clinical trials and news about C8orf47 / CH047
|
Transcripts
for C8orf47 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for C8orf47 gene (2 alternative transcripts): NM_001170806.1 NM_173549.2 Unigene Cluster for C8orf47: Chromosome 8 open reading frame 47 Hs.171455 [show with all ESTs]Unigene Representative Sequence: NM_1735492 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000318528(uc003yih.1) ENST00000545282(uc022ayz.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): C8orf47 (NM_173549) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for C8orf47 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C8orf47 |
Additional cDNA sequence: AK096872.1 BC062359.1 2 DOTS entries: DT.40305140 DT.100746717 22 AceView cDNA sequences: AI567174 BU076117 AK096872 CR621279 BC062359 BM719936 CA950710 NM_173549 BX382911 CD675217 CA950956 BX491612 BU072133 BM676791 AI697720 CB241309 BI115894 BX390635 BX330776 AA312199 AW576772 BF727092
GeneLoc Exon Structure
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Expression
for C8orf47 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| C8orf47 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGAAGGATGT
About this image
See C8orf47 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for C8orf47
SOURCE GeneReport for Unigene cluster: Hs.171455
SABiosciences Custom PCR Arrays for C8orf47
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C8orf47
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat C8orf47 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat C8orf47 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat C8orf47 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C8orf47 |
Orthologs
for C8orf47 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for C8orf47 gene from 1/6 species (see all 6) About this table
ENSEMBL Gene Tree for C8orf47 (if available)
TreeFam Gene Tree for C8orf47 (if available) |
Paralogs
for C8orf47 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for C8orf47 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for C8orf47 (99076539 - 99105838 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for C8orf47: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing C8orf47 |
|
Disorders
/ Diseases
for C8orf47 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
C8orf47 for disorders About GeneDecksing
1  disease for C8orf47: About MalaCardsesophagitis
Export disorders for C8orf47 gene to outside databases
|
Publications
for C8orf47 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for C8orf47 gene integrated from 9 sources:
(articles sorted by number of sources associating them with C8orf47) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Common variants at 5q22 associate with pediatric eosi nophilic esophagitis. (PubMed id 20208534)1 Rothenberg M.E....Hakonarson H. (2010)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
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External Searches for C8orf47 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing C8orf47 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing C8orf47 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing C8orf47 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for C8orf47 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for C8orf47 gene:
Search GeneIP for patents involving C8orf47
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for C8orf47 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for C8orf47 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for C8orf47 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for C8orf47 | | | OriGene Protein Over-expression Lysate for C8orf47 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for C8orf47 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for C8orf47 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for C8orf47 | | OriGene Custom Protein Services for C8orf47 | | | OriGene Custom Immunoassay Development | | |
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| | | | Search Tocris compounds for C8orf47 |
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 | | | C8orf47 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for C8orf47 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for C8orf47 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat C8orf47 |
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